Table 1 Key features of liver inflammation and fibrosis stages*
Liver inflammation stages(G) | Liver fibrosis stages(S) | |||
|---|---|---|---|---|
Stage | Portal area | In lobule | Stage | Fibrosis |
0 | None | None | 0 | None |
1 | Lymphopoiesis within portal area | Hepatocyte hydropic or ballooning degeneration, with/without spotty or focal necrosis | 1 | Mild fibrosis without septa |
2 | Mild piecemeal necrosis | Spotty or focal necrosis, formation of acidophilic bodies | 2 | Moderate fibrosis with few septa |
3 | Moderate piecemeal necrosis | Severe degeneration and necrosis,with formation of necrosis bridge | 3 | Severe fibrosis with numerous septa, but with no sign of false lobules |
4 | Severe piecemeal necrosis | Severe necrosis bridge,multiple lobular necrosis | 4 | Formation of false lobules |