Table 1 Effects of berberine on intestinal tumor multiplicity in Apc ^min/+ mice ( $\overline{x}\pm S$ , n = 10)

30.63 ± 1.69

18.50 ± 1.51*

11.50 ± 2.05^{$, &}

28.00 ± 2.00

16.69 ± 1.03*

10.50 ± 1.77^{$, &}

8.38 ± 1.51

5.25 ± 1.16*

3.88 ± 0.64^{$, §}

9.50 ± 1.77

5.56 ± 0.50*

4.25 ± 1.04^$

10.13 ± 1.55

5.88 ± 0.83*

2.38 ± 0.92^{$, &}

8.13 ± 0.83

6.81 ± 0.65^#

5.25 ± 1.04^{$, §}

10.13 ± 1.36

6.19 ± 0.84*

3.25 ± 0.46^{$, &}

9.75 ± 2.05

3.69 ± 1.03*

2.00 ± 0.76^{$, §}

2.63 ± 0.74

1.81 ± 0.65^#

1.00 ± 0.46^{$, §}