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Table 2 The association between NAFLD and serum testosterone levels in the 495 subjects included in the study

From: A low level of serum total testosterone is independently associated with nonalcoholic fatty liver disease

 

Model 1*

Model 2†

Model 3‡

Total testosterone (ng/mL)

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

1st quintile (0.11–3.17),

5.12 (2.43–10.77)

0.0004

4.99 (2.36–10.57)

0.0006

4.52 (2.09–9.80)

0.0040

2nd quintile (3.18–3.88)

2.62 (1.28–5.38)

2.48 (1.20–5.12)

2.31 (1.09–4.88)

3rd quintile (3.92–4.78)

3.39 (1.68–6.84)

3.33 (1.65–6.75)

2.72 (1.31–5.65)

4th quintile (4.80–5.70)

2.30 (1.12–4.70)

2.22 (1.09–4.57)

2.01 (0.96–4.23)

5th quintile (5.71–13.43)

1

1

1

p for the trend

< 0.001

 

< 0.001

 

< 0.001

 
  1. a Multiple logistic regression was used to analyze the associations between NAFLD and serum total testosterone levels.
  2. b p value: tested by the Wald test.
  3. * Model 1: adjusted for age, smoking, diabetes, exercise, BMI, TGs, and HDL-C.
  4. † Model 2: Model 1 + HOMA-IR and hs-CRP.
  5. ‡ Model 3: Model 2 + VAT (as the continuous variable).
  6. OR, odds ratio; CI, confidence interval.