Figure 3

Profile of creatinine, ammonia, lactate and endotoxin in control and dummy device group. The chart demonstrates the course of the selected laboratory values creatinine, A, ammonia, B, lactate, C and endotoxin, D of the control (grey line) and dummy device group (black line) animals. A statistical significance (p < 0.05) could be detected for blood lactate starting from 16 hours, serum creatinine from 40 hours and arterial ammonia from 48 hours after hepatectomy. At time of death no differences were noticed for creatinine, ammonia and lactate, but a statistically significant (p < 0.05) rise of endotoxin serum levels indicated severe sepsis in 60% of the animals surviving beyond 60 hours from hepatectomy. Values are given as mean ± SEM in relation to time after hepatectomy (in hours). Bold marks indicate connection cycles to the dummy device.