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Table 2 Rates of correct classification (%, bold characters) as a function of diagnostic means in population #1.

From: Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C

 

Significant fibrosis (FM ≥ 2)

Fibrosis degree a

p b

Local pathologists

85.9

64.4

< 10-3

Expert pathologist

91.4

82.2

< 10-3

Fibrotest (FT)

74.2

34.3

< 10-3

FibroMeter2G (FM2G)

75.3

76.3

0.860

FibroMeter3G (FM3G)

75.5

89.0

< 10-3

Comparison b:

p

p

-

   All

< 10-3

< 10-3

-

   Local pathologist vs. expert

0.184

< 10-3

-

   Local pathologist vs. FT

0.003

< 10-3

-

   Local pathologist vs. FM2G

0.005

0.007

-

   Local pathologist vs. FM3G

0.004

< 10-3

-

   Expert pathologist vs. FT

< 10-3

< 10-3

-

   Expert pathologist vs. FM2G

< 10-3

0.092

-

   Expert pathologist vs. FM3G

< 10-3

0.126

-

   FT vs. FM2G

0.839

< 10-3

-

   FT vs. FM3G

0.878

< 10-3

-

   FM2G vs. FM3G

1

< 10-3

-

  1. The reference is consensus reading of liver biopsy.
  2. a Metavir staging for pathologist or fibrosis class classification for blood tests
  3. b By McNemar test (pair) or Friedman test (all)
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BMC Gastroenterology

ISSN: 1471-230X

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