Table 3 Number of 16S rRNA gene copies detected.
IBS* | IBS-D** | ||||||
|---|---|---|---|---|---|---|---|
qPCR assay | (m) | Probiotic (n = 22) | Placebo (n = 20) | P | Probiotic (n = 11) | Placebo (n = 8) | P |
Bacteroides intestinalis-like | 0 | 2.33 ± 0.69 | 2.65 ± 0.77 | 0.61 | 2.21 ± 0.80 | 1.52 ± 0.37 | 0.24 |
3 | 2.49 ± 0.81 | 2.02 ± 0.60 | 0.52 | 2.38 ± 1.12 | 1.43 ± 0.60 | 0.20 | |
6 | 2.53 ± 0.81 | 2.30 ± 0.74 | 0.92 | 2.45 ± 1.14 | 1.19 ± 0.51 | 0.11 | |
Clostridium cocleatum 88% | 0 | 5.17 ± 0.73 | 4.98 ± 0.95 | 0.72 | 5.03 ± 1.03 | 4.07 ± 1.66 | 0.23 |
3 | 5.06 ± 0.79 | 5.11 ± 0.95 | 0.93 | 5.07 ± 1.03 | 4.52 ± 1.81 | 0.53 | |
6 | 5.14 ± 0.72 | 4.92 ± 0.85 | 0.72 | 5.39 ± 0.99 | 4.56 ± 1.65 | 0.33 | |
Clostridium thermosuccinogenes 85% | 0 | 4.00 ± 0.55 | 3.94 ± 0.52 | 0.63 | 3.79 ± 0.63 | 3.52 ± 0.80 | 0.29 |
3 | 5.05 ± 0.37 | 3.46 ± 0.39 | 0.00 | 4.88 ± 0.53 | 3.64 ± 0.47 | 0.01 | |
6 | 4.87 ± 0.41 | 3.91 ± 0.46 | 0.02 | 4.71 ± 0.67 | 3.54 ± 0.53 | 0.05 | |
Collinsella aerofaciens-like | 0 | 4.57 ± 0.63 | 4.14 ± 0.69 | 0.35 | 4.36 ± 0.96 | 3.13 ± 1.00 | 0.06 |
3 | 4.33 ± 0.72 | 4.10 ± 0.71 | 0.70 | 3.91 ± 1.15 | 3.01 ± 0.96 | 0.25 | |
6 | 4.32 ± 0.68 | 4.45 ± 0.68 | 0.71 | 3.92 ± 1.06 | 3.79 ± 1.12 | 0.91 | |
Coprococcus eutactus 97% | 0 | 2.62 ± 0.73 | 2.99 ± 0.69 | 0.84 | 2.95 ± 1.26 | 2.49 ± 0.53 | 0.28 |
3 | 2.75 ± 0.65 | 2.94 ± 0.69 | 0.94 | 3.42 ± 1.10 | 2.63 ± 1.02 | 0.20 | |
6 | 2.77 ± 0.60 | 3.03 ± 0.64 | 0.85 | 3.15 ± 0.97 | 2.53 ± 0.78 | 0.22 | |
Ruminococcus torques 91% | 0 | 4.29 ± 0.36 | 4.27 ± 0.32 | 0.93 | 4.17 ± 0.44 | 4.36 ± 0.47 | 0.60 |
3 | 4.22 ± 0.28 | 4.34 ± 0.40 | 0.64 | 4.10 ± 0.42 | 4.54 ± 0.70 | 0.23 | |
6 | 4.05 ± 0.39 | 4.05 ± 0.40 | 1.00 | 3.73 ± 0.61 | 4.21 ± 0.53 | 0.19 | |
Ruminococcus torques 93% | 0 | 5.17 ± 0.20 | 5.39 ± 0.17 | 0.19 | 5.04 ± 0.27 | 5.45 ± 0.30 | 0.09 |
3 | 5.25 ± 0.17 | 4.42 ± 0.26 | 0.00 | 5.37 ± 0.28 | 4.70 ± 0.41 | 0.00 | |
6 | 5.00 ± 0.36 | 4.50 ± 0.20 | 0.00 | 4.73 ± 0.64 | 4.57 ± 0.15 | 0.50 | |
Ruminococcus torques 94% | 0 | 3.54 ± 0.61 | 4.14 ± 0.53 | 0.10 | 3.69 ± 0.87 | 4.75 ± 0.49 | 0.04 |
3 | 3.48 ± 0.60 | 3.97 ± 0.57 | 0.30 | 3.48 ± 0.92 | 4.42 ± 0.90 | 0.14 | |
6 | 3.06 ± 0.61 | 4.07 ± 0.43 | 0.02 | 2.72 ± 0.90 | 4.41 ± 0.66 | 0.01 |