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  1. The body is dependent on the exogenous supply of omega-3 polyunsaturated fatty acids (n3-PUFA). These essential fatty acids are key players in regulating metabolic signaling but also exert anti-inflammatory an...

    Authors: Michael Linecker, Perparim Limani, Florin Botea, Irinel Popescu, Ruslan Alikhanov, Michail Efanov, Pavel Kim, Igor Khatkov, Dimitri Aristotele Raptis, Christoph Tschuor, Beatrice Beck-Schimmer, John Bonvini, Andrea Wirsching, Philipp Kron, Ksenija Slankamenac, Bostjan Humar…
    Citation: BMC Gastroenterology 2015 15:102
  2. Unchanged substrate in a negative rapid urease test may be reused to detect Helicobacter pylori (H. pylori). This could potentially reduce costs and wastage in low prevalence and resource-poor settings. We thus a...

    Authors: Shahidi Jamaludin, Nazri Mustaffa, Nor Aizal Che Hamzah, Syed Hassan Syed Abdul Aziz and Yeong Yeh Lee
    Citation: BMC Gastroenterology 2015 15:101
  3. Obesity has become one of the most serious social problems in developed countries, including Japan. The relationship between the gut microbiota and obesity has recently attracted the attention of many research...

    Authors: Chika Kasai, Kazushi Sugimoto, Isao Moritani, Junichiro Tanaka, Yumi Oya, Hidekazu Inoue, Masahiko Tameda, Katsuya Shiraki, Masaaki Ito, Yoshiyuki Takei and Kojiro Takase
    Citation: BMC Gastroenterology 2015 15:100
  4. Adenomyomatosis of gallbladder is an acquired hyperplastic lesion, characterized by focal or diffuse thickening of the gallbladder with intramural cysts or echogenic areas with comet tail on ultrasonography. B...

    Authors: ShaoShan Tang, LiPing Huang, Yao Wang and YiJiao Wang
    Citation: BMC Gastroenterology 2015 15:99
  5. The combination of sofosbuvir (SOF), ribavirin (RBV) and peg-interferon-alfa-2a (peg-IFN-alfa-2a) as well as the combination of SOF and RBV for the treatment of patients infected with hepatitis c virus (HCV) h...

    Authors: Niels Steinebrunner, Martin F. Sprinzl, Tim Zimmermann, Marcus A. Wörns, Thomas Zimmerer, Peter R. Galle, Wolfgang Stremmel, Christoph Eisenbach, Kerstin Stein, Christoph Antoni, Jörn M. Schattenberg and Anita Pathil
    Citation: BMC Gastroenterology 2015 15:97
  6. Transarterial-chemo-embolization (TACE) is used for palliation of unresectable hepatocellular carcinoma (HCC). We studied the tolerability of TACE in a cohort of patients with NASH and alcoholic cirrhosis rela...

    Authors: Rohan Chaminda Siriwardana, Madunil Anuk Niriella, Anuradha Supun Dassanayake, Chandika Anuradha Habarakada Liyanage, Angappulige Upasena, Chandra Sirigampala and Hithanadura Janaka de Silva
    Citation: BMC Gastroenterology 2015 15:96
  7. The grade of gastric mucosa atrophy caused by Helicobacter pylori (H. pylori) infection is closely associated with the risk of gastric cancer, especially of the intestinal type. Interobserver and intraobserver ag...

    Authors: Tomohiro Miwata, Duc Trong Quach, Toru Hiyama, Rika Aoki, Huy Minh Le, Phuong Luu Ngoc Tran, Masanori Ito, Shinji Tanaka, Koji Arihiro, Naomi Uemura and Kazuaki Chayama
    Citation: BMC Gastroenterology 2015 15:95
  8. The NF-kB signaling, regulated by IKK1-p52/RelB and IKK2-p65, is activated by various stresses to protect or damage the liver, in context-specific manners. Two previous studies of liver-specific expression of ...

    Authors: Hong Lu, Xiaohong Lei and Qinghao Zhang
    Citation: BMC Gastroenterology 2015 15:94
  9. Many patients with inflammatory bowel disease strongly believe that food or certain food products heavily influence the symptoms or even trigger acute flare-ups. Unfortunately, there is no generalizable inform...

    Authors: Alexander Palant, Janka Koschack, Simone Rassmann, Gabriele Lucius-Hoene, Michael Karaus and Wolfgang Himmel
    Citation: BMC Gastroenterology 2015 15:93
  10. Autoimmune hepatitis causes chronic hepatitis and often leads to cirrhosis and death without treatment. We wanted to see if having access to primary care or insurance prior to diagnosis is associated with bett...

    Authors: Daniel Kim, Daniel Eshtiaghpour, Joel Alpern, Anuj Datta, Viktor E. Eysselein and Hal F. Yee
    Citation: BMC Gastroenterology 2015 15:91
  11. Congenital lactase deficiency is an extremely rare gastrointestinal disorder characterized by neonatal-onset watery diarrhoea and failure to thrive. We present the first genetically confirmed case of congenita...

    Authors: Walid Fazeli, Sigrid Kaczmarek, Martin Kirschstein and René Santer
    Citation: BMC Gastroenterology 2015 15:90
  12. For endoscopic interventions, heparin bridging therapy is recommended in patients who are at high risk from interruption of antithrombotic therapy. Although heparin bridging has been reported to be effective i...

    Authors: Mio Matsumoto, Katsuhiro Mabe, Momoko Tsuda, Masayoshi Ono, Saori Omori, Masakazu Takahashi, Takeshi Yoshida, Shoko Ono, Manabu Nakagawa, Soichi Nakagawa, Yuichi Shimizu, Takahiko Kudo, Naoya Sakamoto and Mototsugu Kato
    Citation: BMC Gastroenterology 2015 15:89
  13. Coffee consumption has been associated with reduced risk of developing type 2 diabetes mellitus (T2DM) however, the mechanism for this association has yet to be elucidated. Non-alcoholic fatty liver disease (N...

    Authors: J. C. Dickson, A. D. Liese, C. Lorenzo, S. M. Haffner, S. M. Watkins, S. J. Hamren, J. K. Stiles, L. E. Wagenknecht and A. J. Hanley
    Citation: BMC Gastroenterology 2015 15:88
  14. Studies concerning clinical course and outcome of acute pancreatitis (AP) according to etiologies were rare, especially after year 2000. This study was designed to investigate the difference between the clinic...

    Authors: Joon Hyun Cho, Tae Nyeun Kim and Sung Bum Kim
    Citation: BMC Gastroenterology 2015 15:87
  15. Signet ring cell carcinoma of the colon and rectum is rare, and most cases are detected at an advanced stage. We present a case of primary signet ring cell carcinoma detected at an early stage by magnifying en...

    Authors: Ken Ohnita, Hajime Isomoto, Taro Akashi, Keiichi Hashiguchi, Kayoko Matsushima, Hitomi Minami, Yuko Akazawa, Naoyuki Yamaguchi, Fuminao Takeshima, Kazuo To, Hiroaki Takeshita, Haruna Yasui, Kuniko Abe and Kazuhiko Nakao
    Citation: BMC Gastroenterology 2015 15:86
  16. Acute pancreatitis is the most common major complication after endoscopic retrograde cholangiopancreatography (ERCP). Many drugs have been evaluated for prophylaxis, including nonsteroidal anti-inflammatory dr...

    Authors: Víctor Fernando Andrade-Dávila, Mariana Chávez-Tostado, Carlos Dávalos-Cobián, Jesús García-Correa, Alejandro Montaño-Loza, Clotilde Fuentes-Orozco, Michel Dassaejv Macías-Amezcua, Jesús García-Rentería, Jorge Rendón-Félix, José Antonio Cortés-Lares, Gabriela Ambriz-González, Ana Olivia Cortés-Flores, Andrea del Socorro Alvarez-Villaseñor and Alejandro González-Ojeda
    Citation: BMC Gastroenterology 2015 15:85
  17. Desmoid tumors are a group of benign, invasive, solid tumors that are relatively rare in the general population, but can occur in up to 21 % of patients with Familial Adenomatous Polyposis (FAP). They can be d...

    Authors: Voytek Slowik, Thomas Attard, Hongying Dai, Raj Shah and Seth Septer
    Citation: BMC Gastroenterology 2015 15:84
  18. Our previous studies indicated that heat stress can cause significant damage to the intestinal epithelium and induce differential expression of many genes in rat small intestine. The transcription factors AP-1...

    Authors: Yonghong Zhang, Hong Zhao, Tao Liu, Changrong Wan, Xiaoxi Liu, Zhimin Gao, Xiaolin Hou, Linshu Jiang and Fenghua Liu
    Citation: BMC Gastroenterology 2015 15:83
  19. Large colonic polyps are associated with advanced dysplasia, but prevalence and characteristics of synchronous polyps in patients with large flat colonic polyps are poorly investigated. This study aims to char...

    Authors: Tianzuo Zhan, Felix Hahn, Thomas Hielscher, Johannes Betge, Georg Kähler, Matthias P. Ebert and Sebastian Belle
    Citation: BMC Gastroenterology 2015 15:82
  20. Standards in treatment of acute cholecystitis (AC) in the elderly and high-risk patients has not been established. Our study evaluated the efficacy and safety of B-mode ultrasound-guided percutaneous transhepa...

    Authors: Yi-Ren Hu, Jiang-Hua Pan, Xiao-Chun Tong, Ke-Qin Li, Sen-Rui Chen and Yi Huang
    Citation: BMC Gastroenterology 2015 15:81
  21. Carbonic anhydrase IX (CA9) is a transmembrane glycoprotein related to hypoxia. Increased CA9 expression has been associated with decreased survival and cancer progression and has been targeted as a potential ...

    Authors: Aaron R. Huber, Dongfeng Tan, Jun Sun, David Dean, Tongtong Wu and Zhongren Zhou
    Citation: BMC Gastroenterology 2015 15:80
  22. Hepatitis B virus (HBV) genotypes can influence treatment outcome in HBV-monoinfected and human immunodeficiency virus (HIV)/HBV-coinfected patients. Tenofovir disoproxil fumarate (TDF) plays a pivotal role in...

    Authors: Florian Bihl, Gladys Martinetti, Gilles Wandeler, Rainer Weber, Bruno Ledergeber, Alexandra Calmy, Manuel Battegay, Matthias Cavassini, Pietro Vernazza, Anna-Paola Caminada, Martin Rickenbach and Enos Bernasconi
    Citation: BMC Gastroenterology 2015 15:79
  23. Pancreas divisum, the most common congenital anomaly of the pancreas, is caused by failure of the fusion of the ventral and dorsal pancreatic duct systems during embryological development. Although various pan...

    Authors: Takeshi Nishi, Yasunari Kawabata, Noriyoshi Ishikawa, Asuka Araki, Seiji Yano, Riruke Maruyama and Yoshitsugu Tajima
    Citation: BMC Gastroenterology 2015 15:78
  24. Intestinal barrier dysfunction is not only the consequence of liver cirrhosis, but also an active participant in the development of liver cirrhosis. Previous studies showed that external administration of insu...

    Authors: Tian-Yu Zhao, Li-Ping Su, Chun-Ye Ma, Xiao-Han Zhai, Zhi-Jun Duan, Ying Zhu, Gang Zhao, Chun-Yan Li, Li-Xia Wang and Dong Yang
    Citation: BMC Gastroenterology 2015 15:77
  25. The treatment of colon cancer located in splenic flexure is not standardized. Laparoscopic approach is still considered a challenging procedure. This study reviews two Institutions experience in laparoscopic t...

    Authors: Andrea Pisani Ceretti, Nirvana Maroni, Matteo Sacchi, Stefano Bona, Maria Rachele Angiolini, Paolo Bianchi, Enrico Opocher and Marco Montorsi
    Citation: BMC Gastroenterology 2015 15:76
  26. Abnormal handling of E. coli by lamina propria (LP) macrophages may contribute to Crohn’s disease (CD) pathogenesis. We aimed to determine LP macrophage phenotypes in CD, ulcerative colitis (UC) and healthy contr...

    Authors: Timothy R. Elliott, Neil B. Rayment, Barry N. Hudspith, Rebecca E. Hands, Kirstin Taylor, Gareth C. Parkes, Natalie J. Prescott, Liljana Petrovska, John Hermon-Taylor, Jonathan Brostoff, Alex Boussioutas, Christopher G. Mathew, Stephen A. Bustin and Jeremy D. Sanderson
    Citation: BMC Gastroenterology 2015 15:75
  27. Cholesterol metabolism may be involved in pediatric gallstone disease. We aimed to reveal cholesterol metabolites and phytosterols and their relation to stone composition of sterols in children having black pi...

    Authors: Antti Koivusalo, Mikko Pakarinen, Helena Gylling and Markku J. Nissinen
    Citation: BMC Gastroenterology 2015 15:74
  28. Implementation of surveillance programs for at-risk populations and identification of biomarkers for early hepatocellular carcinoma (HCC) detection are a major public health goal. Recently, osteopontin (OPN) h...

    Authors: Adélia Simão, João Madaleno, Nuno Silva, Fernando Rodrigues, Paula Caseiro, José Nascimento Costa and Armando Carvalho
    Citation: BMC Gastroenterology 2015 15:73
  29. Saturated fatty acids are toxic to liver cells and are believed to play a central role in the pathogenesis of non-alcoholic steatohepatitis. In experimental steatohepatitis induced by feeding mice a methionine...

    Authors: Andrew A. Pierce, Michael K. Pickens, Kevin Siao, James P. Grenert and Jacquelyn J. Maher
    Citation: BMC Gastroenterology 2015 15:72
  30. Fibromuscular dysplasia (FMD) is a nonatheromatous, noninflammatory arterial disorder of unknown etiology resulting in vessel stenosis and/or aneurysm formation. The renal and cephalocervical (mainly carotid a...

    Authors: Andrew Mitchell, Véronique Caty and Yves Bendavid
    Citation: BMC Gastroenterology 2015 15:71
  31. Explanation of the ultimate causes of acute and chronic pancreatitis is challenging. Hence, it is necessary to seek various etiological factors, including genetic mutations that may be of importance in trigger...

    Authors: Dorota Koziel, Stanislaw Gluszek, Artur Kowalik, Malgorzata Chlopek and Liliana Pieciak
    Citation: BMC Gastroenterology 2015 15:70
  32. Delayed gastric emptying (DGE) is one of the most frequent complications after pancreaticoduodenectomy (PD). This meta-analysis aimed to evaluate the effect of antecolic versus retrocolic reconstruction of gas...

    Authors: Yanming Zhou, Jincan Lin, Lupeng Wu, Bin Li and Hua Li
    Citation: BMC Gastroenterology 2015 15:68
  33. Intrahepatic biliary mucinous cystic neoplasms are rare hepatic tumors and account for less than 5% of intrahepatic cystic lesions. Accurate preoperative diagnosis is difficult and the outcome differs among va...

    Authors: Chao-Wei Lee, Hsin-I Tsai, Yann-Sheng Lin, Tsung-Han Wu, Ming-Chin Yu and Miin-Fu Chen
    Citation: BMC Gastroenterology 2015 15:67
  34. To investigate in a cohort with previous gastrointestinal infection and a control group the prevalence of overactive bladder syndrome (OAB), and how it was associated with three other functional disorders; irr...

    Authors: Robert Persson, Knut-Arne Wensaas, Kurt Hanevik, Geir Egil Eide, Nina Langeland and Guri Rortveit
    Citation: BMC Gastroenterology 2015 15:66
  35. Ascites is the most common complication of cirrhosis. It may lead to the consequence of poor prognosis and the deterioration of quality of life. Asopressin V2 receptor antagonists is a kind of vaptans, and it ...

    Authors: Long Yan, Feng Xie, Jiongjiong Lu, Qingqiang Ni, Changying Shi, Caixi Tang and Jiamei Yang
    Citation: BMC Gastroenterology 2015 15:65
  36. Laterally spreading tumors (LSTs) are generally defined as lesions >10 mm in diameter, are characterized by lateral expansion along the luminal wall with a low vertical axis. In contrast to other forms of tumo...

    Authors: Shoko Minemura, Takeshi Tanaka, Makoto Arai, Kenichiro Okimoto, Arata Oyamada, Keiko Saito, Daisuke Maruoka, Tomoaki Matsumura, Tomoo Nakagawa, Tatsuro Katsuno, Takashi Kishimoto and Osamu Yokosuka
    Citation: BMC Gastroenterology 2015 15:64
  37. Although sarcoidosis and celiac disease are both chronic immunologic disorders involving multiple organ systems, reports about association of diseases in individual patients are sparse. While sarcoidosis is a ...

    Authors: Tassilo Kruis, Korinna Jöhrens, Verena Moos, Imke Puls, Britta Siegmund, Severin Daum and Michael Schumann
    Citation: BMC Gastroenterology 2015 15:62
  38. Infections in cirrhotic patients with upper gastrointestinal bleeding are a common event causing severe complication and mortality. This study aimed to identify risk factors that may predict rebleeding, bacter...

    Authors: Ming-Te Kuo, Shih-Cheng Yang, Lung-Sheng Lu, Chien-Ning Hsu, Yuan-Hung Kuo, Chung-Huang Kuo, Chih-Ming Liang, Chung-Mou Kuo, Cheng-Kun Wu, Wei-Chen Tai and Seng-Kee Chuah
    Citation: BMC Gastroenterology 2015 15:61
  39. Continuous use of anabolic androgenic steroid in high-doses is associated with substantial health risks, including hepatocellular adenoma. Malignant transformation from hepatocellular adenoma to hepatocellular...

    Authors: Philipp Solbach, Andrej Potthoff, Hans-Jürgen Raatschen, Bisharah Soudah, Ulrich Lehmann, Andrea Schneider, Michael J. Gebel, Michael P. Manns and Arndt Vogel
    Citation: BMC Gastroenterology 2015 15:60
  40. Endoscopic sphincterotomy (EST) is currently recognized as the primary endoscopic treatment for common bile duct stones. However, it is difficult to remove multiple (≥3) or large (≥15 mm) common bile duct ston...

    Authors: Kouhei Tsuchida, Mari Iwasaki, Misako Tsubouchi, Tsunehiro Suzuki, Chieko Tsuchida, Naoto Yoshitake, Takako Sasai and Hideyuki Hiraishi
    Citation: BMC Gastroenterology 2015 15:59
  41. Several association studies with small sample sizes of two SNPs in IL28BB (rs12979860 and rs8099917) showed inconsistent results, so in this study, we aim to evaluate the association between the two SNPs and i...

    Authors: Jing Chen, Wei Wang, Xiaoguang Li and Jie Xu
    Citation: BMC Gastroenterology 2015 15:58
  42. Reasons underlying the variability of physicians’ preferences for non-selective beta-blockers (BBs) and endoscopic variceal ligation (EVL) to prevent a first variceal bleed have not been empirically studied. O...

    Authors: Kathleen Yan, John FP Bridges, Salvador Augustin, Loren Laine, Guadalupe Garcia-Tsao and Liana Fraenkel
    Citation: BMC Gastroenterology 2015 15:55
  43. Studies have demonstrated usefulness of cognitive-behavioural therapy (CBT) in managing distress in inflammatory bowel disease (IBD); however, few have focused on IBD course. The present trial aimed to investi...

    Authors: Antonina Mikocka-Walus, Peter Bampton, David Hetzel, Patrick Hughes, Adrian Esterman and Jane M Andrews
    Citation: BMC Gastroenterology 2015 15:54
  44. Oral tacrolimus therapy is effective for refractory ulcerative colitis (UC), but dose adjustment according to the trough concentrations which varies largely among individuals, is required. This study aimed to ...

    Authors: Sakiko Hiraoka, Jun Kato, Yuki Moritou, Daisuke Takei, Toshihiro Inokuchi, Asuka Nakarai, Sakuma Takahashi, Keita Harada, Hiroyuki Okada and Kazuhide Yamamoto
    Citation: BMC Gastroenterology 2015 15:53

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