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  1. The reflux of noxious contents of the stomach may cause oesophageal and extra-oesophageal complications either by direct contact of aspirated gastric refluxate with the upper airway or by a vago-vagal reflex. ...

    Authors: Moses Ayodele Akinola, Titus Ayodeji Oyedele, Kolawole Oluseyi Akande, Olukayode Yinka Oluyemi, Omotayo Felicia Salami, Alaba Moses Adesina and Adedeji David Adebajo
    Citation: BMC Gastroenterology 2020 20:160
  2. Post-infectious Irritable Bowel Syndrome (PI-IBS) is a functional bowel disorder which has significant impacts to a patient’s quality of life. No IBS-specific biomarker or treatment regimen for PI-IBS currentl...

    Authors: Erika Austhof, Kenzie Schaefer, Jaime Faulkner, Laura Bach, Mark Riddle and Kristen Pogreba-Brown
    Citation: BMC Gastroenterology 2020 20:159
  3. Endoscopic retrograde cholangiopancreatography (ERCP) is still performed using two-dimensional (2D) X-ray images. The success rate and risk of complications are considered operator-dependent. We explored perfo...

    Authors: Masao Toki, Hidekatsu Tateishi, Tsubasa Yoshida, Koichi Gondo, Shunsuke Watanabe and Tadakazu Hisamatsu
    Citation: BMC Gastroenterology 2020 20:158
  4. Intestinal perforation from peritoneal dialysis is rare, but the resulting complications are serious. Some patients do not necessarily have symptoms, and it can be difficult to differentiate their condition fr...

    Authors: Qiuyuan Shao, Yangyang Xia, Qingyan Zhang and Miao Zhang
    Citation: BMC Gastroenterology 2020 20:157
  5. Gastric cancer (GC) is a malignant tumour originating from the gastric mucosa epithelium that seriously threatens human health. DCLK1, miR-15b and lncRNA SNHG1 play potential roles in the occurrence of GC, but...

    Authors: Zhi-Qi Liu, Wei-Feng He, Yang-Jie Wu, Shun-Li Zhao, Ling Wang, Yan-Yi Ouyang and San-Yuan Tang
    Citation: BMC Gastroenterology 2020 20:156
  6. Many studies have found that large tumor suppressor kinase 1 (LATS1) and LATS2 play important roles in many diseases, but studies have been rare on the relationship between these genes and non-cardia gastric c...

    Authors: Li-cong Ma, Xu-yang Tian, Fang Gao, Wen-jie Dong, Tong Dang and Yan-bin Jia
    Citation: BMC Gastroenterology 2020 20:155
  7. Indigo naturalis is a Chinese herbal medicine that has currently been used to treat various inflammatory diseases, including ulcerative colitis. Recently, there are several reports concerning severe adverse ev...

    Authors: Byungha Cho, Soon Man Yoon, Seung-Myoung Son, Hyoung Woo Kim, Ki Bae Kim and Sei Jin Youn
    Citation: BMC Gastroenterology 2020 20:154
  8. Oesophageal stents have several well-known respiratory complications, including aspiration pneumonia, fistula and airway compression. However, bilateral vocal cord paralysis has rarely been described.

    Authors: Y. Chiche, G. Beltramo, T. Degand, A. Drouillard, C. Foignot, N. Baudouin, P. Bonniaud and M. Georges
    Citation: BMC Gastroenterology 2020 20:153
  9. Gastric cancer (GC) is a world health problem and it is the third leading cause of cancer deaths worldwide. The current practice for prognosis assessment in GC is based on radiological and pathological criteri...

    Authors: Javad Behroozi, Shirin Shahbazi, Mohammad Reza Bakhtiarizadeh and Habibollah Mahmoodzadeh
    Citation: BMC Gastroenterology 2020 20:152
  10. Antibiotic-associated diarrhea (AAD) occurs in 2–25% of nursing home residents, which may lead to dehydration, malnutrition, severe complications and hospitalizations. Research shows that probiotics can be eff...

    Authors: Herman A. van Wietmarschen, Martine Busch, Annemiek van Oostveen, Gerda Pot and Miek C. Jong
    Citation: BMC Gastroenterology 2020 20:151
  11. Polyethylene glycol solution (PEG) is widely used for bowel preparation prior to colonoscopies. However, patients often exhibited adverse events as nausea, vomit and distention due to its uncomfortable tastes ...

    Authors: Zong Hao, Lifeng Gong, Qiang Shen, Huipeng Wang, Shaowen Feng, Xin Wang, Yuankun Cai and Jun Chen
    Citation: BMC Gastroenterology 2020 20:150
  12. Endoscopic retrograde biliary drainage (ERBD) is the most frequently performed procedure for treating benign or malignant biliary obstruction. Although duodenal perforations secondary to the biliary plastic st...

    Authors: Xiaopeng Wang, Junwen Qu and Kewei Li
    Citation: BMC Gastroenterology 2020 20:149
  13. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are widely used techniques for the treatment of gastric epithelial dysplasia. Previous studies have compared the clinical outcome o...

    Authors: Min Kyung Back, Hee Seok Moon, In Sun Kwon, Jae Ho Park, Ju Seok Kim, Sun Hyung Kang, Jae Kyu Sung, Eaum Seok Lee, Seok Hyun Kim, Byung Seok Lee and Hyun Yong Jeong
    Citation: BMC Gastroenterology 2020 20:148
  14. Incidence of ulcerative colitis (UC) in elderly population is increasing because of ageing and because of its minimal impact on life span. Data on natural history, outcomes and therapeutic strategies are limited.

    Authors: Irene Zammarchi, Francesco Lanzarotto, Rosanna Cannatelli, Francesca Munari, Federica Benini, Alessandro Pozzi, Alberto Lanzini and Chiara Ricci
    Citation: BMC Gastroenterology 2020 20:147
  15. The impact of hepatic steatosis (HS) on treatment response following nucleos(t)ide analogue (NA) treatment for chronic hepatitis B (CHB) patients has not been clearly elucidated. We aimed to investigate the di...

    Authors: Yi-Cheng Chen, Wen-Juei Jeng, Chao-Wei Hsu and Chun-Yen Lin
    Citation: BMC Gastroenterology 2020 20:146
  16. ERCP training models are very different in terms of anatomical differences, ethical issues, storage problems, realistic tactile sensation, durability and portability. There is no easy way to select an optimize...

    Authors: Chang-Il Kwon, Yeonsun Shin, Jaeok Hong, Minje Im, Guk Bae Kim, Dong Hee Koh, Tae Jun Song, Won Suk Park, Jong Jin Hyun and Seok Jeong
    Citation: BMC Gastroenterology 2020 20:145
  17. Nausea is a common symptom in youth with chronic abdominal pain. The aims of the current study were to assess: 1) the frequency of nausea in patients with functional dyspepsia (FD) and irritable bowel syndrome...

    Authors: Craig Friesen, Meenal Singh, Vivekanand Singh and Jennifer V. Schurman
    Citation: BMC Gastroenterology 2020 20:144
  18. Type 2 diabetes mellitus (T2DM) increased the risk of developing pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) is the most common neoplastic disease originating from the pancreas. Increasing evide...

    Authors: Ji-bin Yin, Na Li, Ming-ming Cui, Xin Wang and Rui-tao Wang
    Citation: BMC Gastroenterology 2020 20:143
  19. Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive disorder caused by mutations in TYMP gene, encoding nuclear thymidine phosphorylase (TP). MNGIE mainly presents with gas...

    Authors: Parham Habibzadeh, Mohammad Silawi, Hassan Dastsooz, Shima Bahramjahan, Shahrokh Ezzatzadegan Jahromi, Vahid Reza Ostovan, Majid Yavarian, Mohammad Mofatteh and Mohammad Ali Faghihi
    Citation: BMC Gastroenterology 2020 20:142
  20. Histoplasma capsulatum is the most common endemic mycosis in the United States and frequently presents as an opportunistic infection in immunocompromised hosts. Though liver involvement is common in disseminated ...

    Authors: Steven Park, Janice Cheong, Kaitlin Kyi, Jose Aranez, Sohaib Abu-Farsakh, Christa Whitney-Miller, Bandar Al-Judaibi and Marie Laryea
    Citation: BMC Gastroenterology 2020 20:141
  21. Antiviral therapy for chronic hepatitis B (CHB) is effective and can substantially reduce the risk of progressive liver disease and hepatocellular carcinoma but is often administered for an indefinite duration...

    Authors: Nicole L. Allard, Jennifer H. MacLachlan, Anouk Dev, James Dwyer, Geeta Srivatsa, Timothy Spelman, Alexander J. Thompson and Benjamin C. Cowie
    Citation: BMC Gastroenterology 2020 20:140
  22. There is a discrepancy between west and east on the relationship between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). This study aimed to find out the possible reason for this an...

    Authors: Min Zhang, Su Lin, Ming-fang Wang, Jiao-feng Huang, Shi-ying Liu, Su-mei Wu, Hao-yang Zhang, Zi-mu Wu, Wen-Yue Liu, Dong-Chu Zhang, Chuan-ming Hao, Yue-yong Zhu, Ming-Hua Zheng and Xiao-zhong Wang
    Citation: BMC Gastroenterology 2020 20:139
  23. The relationship between metabolic syndrome (MetS) and Barrett’s esophagus (BE) is still a challenging issue, and inconsistent results have been reported in different studies. Therefore, this study was conduct...

    Authors: Mohammad Karimian, Majid Salamati and Milad Azami
    Citation: BMC Gastroenterology 2020 20:138
  24. Pancreatic and peri-pancreatic neoplasms encompass a variety of histotypes characterized by a heterogeneous prognostic impact. miRNAs are considered efficient candidate biomarkers due to their high stability i...

    Authors: Caterina Vicentini, Federica Calore, Giovanni Nigita, Paolo Fadda, Michele Simbolo, Nicola Sperandio, Claudio Luchini, Rita T. Lawlor, Carlo Maria Croce, Vincenzo Corbo, Matteo Fassan and Aldo Scarpa
    Citation: BMC Gastroenterology 2020 20:137
  25. Colonic transendoscopic enteral tubing (TET) refers to colonic transendoscopic tube-delivered enteral therapy. Colonic TET has been successfully used for frequent colonic administration of drugs or multiple fe...

    Authors: Ting Zhang, Chuyan Long, Bota Cui, Heena Buch, Quan Wen, Qianqian Li, Xiao Ding, Guozhong Ji and Faming Zhang
    Citation: BMC Gastroenterology 2020 20:135
  26. Abdominal pain may be a presenting symptom of lead poisoning and is often difficult to diagnose. This study aimed to determine the prevalence of abdominal pain in patients seen in the Laghman Hakim Hospital ED...

    Authors: Mahtab Shabani, Seyed Kaveh Hadeiy, Parinaz Parhizgar, Nasim Zamani, Hamid Mehrad, Hossein Hassanian-Moghaddam and Scott Phillips
    Citation: BMC Gastroenterology 2020 20:134

    The Correction to this article has been published in BMC Gastroenterology 2021 21:411

  27. Second-line (2 L) chemotherapies for advanced or metastatic gastric cancer have shown improved survival but there is no commonly accepted standard of care. This study examines real-world patient characteristic...

    Authors: David Gómez-Ulloa, Mayur Amonkar, Smita Kothari, Winson Y. Cheung, Ian Chau, John R. Zalcberg, Núria Lara Suriñach and Alfredo Falcone
    Citation: BMC Gastroenterology 2020 20:133
  28. Third-space endoscopy is a novel, safe, and effective method for treating different gastrointestinal conditions. However, several failed endoscopic procedures are attributed to incomplete myotomy. Lighting dev...

    Authors: Oscar Víctor Hernández Mondragón, Raúl Zamarripa Mottú, Omar Solórzano Pineda, Raúl Alberto Gutierrez Aguilar and Luís Fernando García Contreras
    Citation: BMC Gastroenterology 2020 20:132
  29. Colorectal cancer (CRC) is the second most common malignant disease and the second most common cause of cancer death in Germany. Official CRC screening starts at age 50. As there is evidence that individuals w...

    Authors: Sabine Hoffmann, Alexander Crispin, Doris Lindoerfer, Gaby Sroczynski, Uwe Siebert, Ulrich Mansmann and FARKOR Consortium
    Citation: BMC Gastroenterology 2020 20:131
  30. The role of the fecal microbiota composition for the postoperative disease course of patients with Crohn’s disease (CD) who have undergone ileocecal resection remains to be established. In this study, we inves...

    Authors: Anna Strömbeck, Anders Lasson, Hans Strid, Johanna Sundin, Per-Ove Stotzer, Magnus Simrén, Maria K. Magnusson and Lena Öhman
    Citation: BMC Gastroenterology 2020 20:130
  31. Hereditary diffuse gastric cancer is a rare condition that accounts for approximately 1–3% of all gastric cancer cases. Due to its rapid and invasive growth pattern, it is associated with a very poor prognosis...

    Authors: Elisabeth Niemeyer, Hamid Mofid, Carsten Zornig, Eike-Christian Burandt, Alexander Stein, Andreas Block and Alexander E. Volk
    Citation: BMC Gastroenterology 2020 20:129
  32. Because of high-risk behaviours, sedentary lifestyle and side effects of medications, psychiatric patients are at risk of viral hepatitis, alcohol-related liver disease and non-alcoholic fatty liver disease. W...

    Authors: Terry Cheuk-Fung Yip, Grace Lai-Hung Wong, Yee-Kit Tse, Becky Wing-Yan Yuen, Hester Wing-Sum Luk, Marco Ho-Bun Lam, Michael Kin-Kong Li, Ching Kong Loo, Owen Tak-Yin Tsang, Steven Woon-Choy Tsang, Henry Lik-Yuen Chan, Yun-Kwok Wing and Vincent Wai-Sun Wong
    Citation: BMC Gastroenterology 2020 20:128
  33. Management of diarrhoea-predominant irritable bowel syndrome (IBS-D) is generally based on patient-reported symptoms; however, limited information on symptom severity exists. The objective of the study was to ...

    Authors: Anton Emmanuel, Richard William Goosey, Gwen Wiseman, Stephen Baker and Hans Törnblom
    Citation: BMC Gastroenterology 2020 20:127
  34. One of the most feared complications of endoscopic retrograde cholangiopancreatography (ERCP), with an incidence of 3.5 to 15%, is post ERCP pancreatitis (PEP). Given the role of statins in the reduction of sy...

    Authors: Yousaf Bashir Hadi, Syeda Fatima Naqvi, Abdelhai Abdelqader, Justin Kupec and John Nasr
    Citation: BMC Gastroenterology 2020 20:125
  35. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are considered to reflect the systemic inflammatory response and clinical prognosis. However, the independent prognostic values o...

    Authors: Wei-Long Chang, Wen-Chang Yang, Xiang-Yu Zeng, Cheng-Guo Li, Zhen Xiong, Tao Wang, Rui-Zhi Zhang, Kai-Xiong Tao and Peng Zhang
    Citation: BMC Gastroenterology 2020 20:124
  36. The association between Helicobacter pylori and reflux esophagitis (RE) remains controversial. This study aimed to prospectively evaluate the effect of H. pylori eradication on RE and gastroesophageal reflux (GER...

    Authors: Hee Kyong Na, Jeong Hoon Lee, Se Jeong Park, Hee Jung Park, Sun Ok Kim, Ji Yong Ahn, Do Hoon Kim, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee and Hwoon-Yong Jung
    Citation: BMC Gastroenterology 2020 20:123
  37. Esophagogastroduodenoscopy (EGD) provides an indispensable and unambiguous inspection allowing the discovery upper gastrointestinal lesions. However, many patients are anxious about undergoing EGD. Few studies...

    Authors: Masahiro Sogabe, Toshiya Okahisa, Akira Fukuya, Kaizo Kagemoto, Yasuyuki Okada, Yuka Adachi, Takeshi Kurihara, Toru Nii, Satoshi Teramae, Hironori Tanaka, Tetsu Tomonari, Koichi Okamoto, Hiroshi Miyamoto, Masahiko Nakasono and Tetsuji Takayama
    Citation: BMC Gastroenterology 2020 20:122
  38. For chronic hepatitis B (CHB) patients without willingness to extend the routine duration of interferon (IFN) therapy, it is important to identify patients who will benefit from treatment cessation. Hepatitis ...

    Authors: Shuai Wu, Wenfan Luo, Yin Wu, Hongjie Chen and Jie Peng
    Citation: BMC Gastroenterology 2020 20:121
  39. Cabozantinib was approved by the European Medicines Agency and the Federal Drug Administration as an option for sorafenib-resistant advanced hepatocellular carcinoma, increasing overall survival and progressio...

    Authors: Maximilian Sieg, Michael Hartmann, Utz Settmacher and Habibollah Arefian
    Citation: BMC Gastroenterology 2020 20:120
  40. The majority of colonic obstructions result from colorectal cancer. However, malignancies of extra-colonic origin can also disrupt colorectal patency, and the efficacy of self-expanding metal stents (SEMS) ins...

    Authors: Eui Joo Kim, Sang Hoon Han, Kyoung Oh Kim, Jun-Won Chung, Dong Kyun Park, Kwang An Kwon and Jung Ho Kim
    Citation: BMC Gastroenterology 2020 20:117
  41. The fecal immunochemical test (FIT) is the second most commonly used colorectal cancer (CRC) screening modality in the United States; yet, follow-up of abnormal FIT results with diagnostic colonoscopy is under...

    Authors: Vivy T. Cusumano, Edgar Corona, Diana Partida, Liu Yang, Christine Yu and Folasade P. May
    Citation: BMC Gastroenterology 2020 20:115
  42. Prostaglandin E-major urinary metabolite (PGE-MUM) may be a novel biomarker for evaluating disease activity in ulcerative colitis (UC). We compared its usefulness to that of the fecal immunochemical occult blo...

    Authors: Natsuki Ishida, Takahiro Miyazu, Ryosuke Takano, Satoshi Tamura, Shinya Tani, Takuma Kagami, Mihoko Yamade, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Takahisa Furuta, Hiroaki Miyajima and Ken Sugimoto
    Citation: BMC Gastroenterology 2020 20:114
  43. Hepatitis B e antigen (HBeAg) seroclearance has been considered as the treatment endpoint in HBeAg-positive patients with chronic hepatitis B (CHB). Although HBeAg seroclearance has been accomplished, some asp...

    Authors: Hyun Woong Lee, Jung Il Lee, Saein Kim, Sora Kim, Hye Young Chang and Kwan Sik Lee
    Citation: BMC Gastroenterology 2020 20:113
  44. Small bowel adenocarcinoma (SBA) is a rare malignancy that primarily occurs in the duodenum. Multiple synchronous SBA is unique rare and difficult to diagnose due to non-specific disease presentation. Protocol...

    Authors: Qiwei Li, Tao Chen, Hexi Cui, Xiao Xiao, Chunqiu Chen, Zhenyu Shen, Fu Ji and Lu Yin
    Citation: BMC Gastroenterology 2020 20:112
  45. It is unknown whether narrow-band imaging (NBI) could be more effective than high-definition white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions > 5 mm not comp...

    Authors: Fausto Riu Pons, Montserrat Andreu, Dolores Naranjo, Marco Antonio Álvarez-González, Agustín Seoane, Josep Maria Dedeu, Luis Barranco and Xavier Bessa
    Citation: BMC Gastroenterology 2020 20:111

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