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  1. Aberrant regulation of glycogen synthase kinase-3β (GSK-3β) has been implicated in several human cancers; however, it has not been reported in the gastric cancer tissues to date. The present study was performe...

    Authors: Yu Jin Cho, Ji Hun Kim, Jiyeon Yoon, Sung Jin Cho, Young San Ko, Jong-Wan Park, Hye Seung Lee, Hee Eun Lee, Woo Ho Kim and Byung Lan Lee
    Citation: BMC Gastroenterology 2010 10:91
  2. Protease inhibitors (PI's) and reverse transcriptase drugs are important components of highly active antiretroviral therapy (HAART) for treating human acquired immunodeficiency syndrome (AIDS). Long-term clini...

    Authors: Manuel B Braga Neto, Carolina V Aguiar, Jamilly G Maciel, Bruna MC Oliveira, Jesus E Sevilleja, Reinaldo B Oriá, Gerly AC Brito, Cirle A Warren, Richard L Guerrant and Aldo AM Lima
    Citation: BMC Gastroenterology 2010 10:90
  3. Irritable bowel syndrome (IBS) is commonly regarded as a functional disorder, and is hypothesized to be associated with anxiety and depression. This evidence mainly rests on population-based studies utilising ...

    Authors: Arnstein Mykletun, Felice Jacka, Lana Williams, Julie Pasco, Margaret Henry, Geoffrey C Nicholson, Mark A Kotowicz and Michael Berk
    Citation: BMC Gastroenterology 2010 10:88
  4. The high frequency of local recurrence occurring after endoscopic piecemeal resection (EPMR) for large colorectal tumors is a serious problem. However, almost all of these cases of local recurrence can be dete...

    Authors: Takayoshi Kishino, Takahisa Matsuda, Taku Sakamoto, Takeshi Nakajima, Hirokazu Taniguchi, Seiichiro Yamamoto and Yutaka Saito
    Citation: BMC Gastroenterology 2010 10:87
  5. Glyceryl trinitrate (GTN) has been shown to be able to relax the sphincter of Oddi (SO) both in animals and humans. Theoretically, the use of these compounds during and after endoscopic retrograde cholangiopan...

    Authors: Bin Chen, Tao Fan and Chun-hui Wang
    Citation: BMC Gastroenterology 2010 10:85
  6. We describe a rare case of diffuse macroscopic discoloration and chemical gastritis due to chronic bromazepam intake. The chemical composition of pharmaceuticals has to be considered at endoscopy and it is evi...

    Authors: Oliver Kirschberg, Thomas Saers, Bernd Krakamp and Michael Brockmann
    Citation: BMC Gastroenterology 2010 10:84
  7. The fact that prognoses remain poor in patients with advanced hepatocellular carcinoma highlights the demand for suitable animal models to facilitate the development of anti-cancer medications. This study empl...

    Authors: Hoi-Hung Chan, Tian-Huei Chu, Hsin-Fan Chien, Cheuk-Kwan Sun, E-Ming Wang, Huay-Ben Pan, Hsiao-Mei Kuo, Tsung-Hui Hu, Kwok-Hung Lai, Jiin-Tsuey Cheng and Ming-Hong Tai
    Citation: BMC Gastroenterology 2010 10:83
  8. We have previously found that TLR4-deficient (TLR4-/-) mice demonstrate decreased expression of mucosal PGE 2 and are protected against colitis-associated neoplasia. However, it is still unclear whether PGE 2 is ...

    Authors: Yasmin Hernandez, John Sotolongo, Keith Breglio, Daisy Conduah, Anli Chen, Ruliang Xu, David Hsu, Ryan Ungaro, Lory A Hayes, Cristhine Pastorini, Maria T Abreu and Masayuki Fukata
    Citation: BMC Gastroenterology 2010 10:82
  9. Hemobilia is a rare but lethal biliary tract complication. There are several causes of hemobilia which might be classified as traumatic or nontraumatic. Hemobilia caused by pseudoaneurysm might result from hep...

    Authors: Yueh-Tsung Lee, Ho Lin, Kuan-Yung Chen, Hurng-Sheng Wu, Min-Ho Hwang and Sheng-Lei Yan
    Citation: BMC Gastroenterology 2010 10:81
  10. In the setting of chronic liver injury in humans, epidermal growth factor (EGF) and EGF receptor (EGFR) are up-regulated and have been proposed to have vital roles in both liver regeneration and development of...

    Authors: Tsutomu Fujii, Bryan C Fuchs, Suguru Yamada, Gregory Y Lauwers, Yakup Kulu, Jonathan M Goodwin, Michael Lanuti and Kenneth K Tanabe
    Citation: BMC Gastroenterology 2010 10:79
  11. There is no clear consensus on the better therapy [radiofrequency ablation (RFA) versus hepatic resection (HR)] for small hepatocellular carcinoma (HCC) eligible for surgical treatments. This study is a meta-a...

    Authors: Yanming Zhou, Yanfang Zhao, Bin Li, Donghui Xu, Zhengfeng Yin, Feng Xie and Jiamei Yang
    Citation: BMC Gastroenterology 2010 10:78
  12. The reprocessing of medical endoscopes is carried out using automatic cleaning and disinfection machines. The documentation and archiving of records of properly conducted reprocessing procedures is the last an...

    Authors: Bernd Krakamp, Oliver Kirschberg, Andreas Scheding, Dieter Emmerich, Stefanie Klein and Thomas Saers
    Citation: BMC Gastroenterology 2010 10:76
  13. Hemobilia is a rare cause of upper GI bleeding and the reasons for the majority of the cases are iatrogenic. It is also one of the rarest vascular complication following laparoscopic cholecystectomy but acute ...

    Authors: Halil Alis, Mehmet A Bozkurt, Osman Z Oner, Kemal Dolay, Ahmet N Turhan, Adem Uçar, Ercan Inci and Ersan Aygun
    Citation: BMC Gastroenterology 2010 10:75
  14. Patients with IBD and chronic inflammation refractory to conventional therapy often demonstrate higher risk of serious complications. Combinations of immunosuppression and biological treatment as well as surgi...

    Authors: Annelie Lindberg, Michael Eberhardson, Mats Karlsson and Per Karlén
    Citation: BMC Gastroenterology 2010 10:73
  15. Although micronutrient supplementation can reduce morbidity and mortality due to diarrhoea, nutritional influences on intestinal host defence are poorly understood. We tested the hypothesis that micronutrient ...

    Authors: Paul Kelly, Tamara Shawa, Stayner Mwanamakondo, Rose Soko, Geoff Smith, G Robin Barclay and Ian R Sanderson
    Citation: BMC Gastroenterology 2010 10:72
  16. Hepatitis B immune globulins (HBIG) in combination with nucleos(t)ide analogues (NA) are effectively used for the prevention of hepatitis B virus (HBV) recurrence after liver transplantation (LT). However, ass...

    Authors: Florian Bihl, Stefan Russmann, Vanina Gurtner, Loriana Di Giammarino, Loredana Pizzi-Bosman, Martine Michel, Andreas Cerny, Antoine Hadengue, Pietro Majno, Emiliano Giostra, Damiano Castelli and Gilles Mentha
    Citation: BMC Gastroenterology 2010 10:71
  17. Intra-organ and intra-vascular pressures can be used to estimate intra-abdominal pressure. The aim of this prospective, interventional study was to assess the effect of PEEP on the accuracy of pressure estimat...

    Authors: Stephan M Jakob, Rafael Knuesel, Jyrki J Tenhunen, Richard Pradl and Jukka Takala
    Citation: BMC Gastroenterology 2010 10:70
  18. Recurrence and severity of Crohn's disease mucosal lesions after "curative" ileal resection is assessed at endoscopy. Intramural lesions can be detected as increased wall thickness at Small Intestine Contrast ...

    Authors: Nadia Pallotta, Maurizio Giovannone, Patrizio Pezzotti, Alessandro Gigliozzi, Fausto Barberani, Daria Piacentino, Naima Abdulkadir Hassan, Giuseppina Vincoli, Mauro Tosoni, Alfredo Covotta, Adriana Marcheggiano, Mauro Di Camillo and Enrico Corazziari
    Citation: BMC Gastroenterology 2010 10:69
  19. Pancreatic cancer has significant morbidity and mortality worldwide. Good prognosis relies on an early diagnosis. The purpose of this study was to develop techniques for identifying cancer biomarkers in the se...

    Authors: Yefei Rong, Dayong Jin, Chenrui Hou, Jianwen Hu, Wenchuan Wu, Xiaolin Ni, Dansong Wang and Wenhui Lou
    Citation: BMC Gastroenterology 2010 10:68
  20. Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver diseases, ranging from pure steatosis to nonalcoholic steatohepatitis (NASH), and eventually to liver cirrhosis with its complications...

    Authors: Joanna Raszeja-Wyszomirska, Barbara Szymanik, Małgorzata Ławniczak, Maciej Kajor, Alina Chwist, Piotr Milkiewicz and Marek Hartleb
    Citation: BMC Gastroenterology 2010 10:67
  21. Doublecortin and calcium/calmodulin-dependent protein kinase-like-1 (DCAMKL1) is a candidate marker for progenitor cells in the gastrointestinal mucosa. Lineage cells in the gastric mucosa are derived from pro...

    Authors: Miho Kikuchi, Hiroshi Nagata, Norihito Watanabe, Hiromitsu Watanabe, Masayuki Tatemichi and Toshifumi Hibi
    Citation: BMC Gastroenterology 2010 10:65
  22. Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host. Therefore, polymorphisms in genes i...

    Authors: Yvana C Jorge, Marcia C Duarte and Ana E Silva
    Citation: BMC Gastroenterology 2010 10:64
  23. There is insufficient evidence on the effectiveness of acupuncture for irritable bowel syndrome (IBS) for conclusions to be drawn. Given the current interest in acupuncture by patients, it is in the public int...

    Authors: Hugh MacPherson, Martin Bland, Karen Bloor, Helen Cox, David Geddes, Arthur Kang'ombe, Julie Reynolds, Eugena Stamuli, Tracey Stuardi, Helen Tilbrook, David Torgerson and Peter Whorwell
    Citation: BMC Gastroenterology 2010 10:63
  24. Helicobacter pylori is one of the most common causes of bacterial infection in human beings. Studies have showed a high prevalence of Helicobacter pylori among people in low-income countries and colonization ear...

    Authors: Elin Hestvik, Thorkild Tylleskar, Deogratias H Kaddu-Mulindwa, Grace Ndeezi, Lena Grahnquist, Edda Olafsdottir and James K Tumwine
    Citation: BMC Gastroenterology 2010 10:62
  25. Clinical management of rectal cancer patients relies on pre-operative staging. Studies however continue to report moderate degrees of over/understaging as well as inter-observer variability. The aim of this st...

    Authors: Inti Zlobec, Parham Minoo, Eva Karamitopoulou, George Peros, Efstratios S Patsouris, Frank Lehmann and Alessandro Lugli
    Citation: BMC Gastroenterology 2010 10:61
  26. Peroxisome proliferator-activated receptor γ (PPAR γ) is a nuclear receptor whose activation has been shown to modulate macrophage and T cell-mediated inflammation. The objective of this study was to investiga...

    Authors: Amir J Guri, Saroj K Mohapatra, William T Horne II, Raquel Hontecillas and Josep Bassaganya-Riera
    Citation: BMC Gastroenterology 2010 10:60
  27. Visceral artery aneurysms (VAA), although uncommon, are increasingly being detected. We describe a case of spontaneous retroperitoneal hemorrhage from a ruptured IMA aneurysm associated with stenosis of the su...

    Authors: P Pérez-Vallecillos, R Conde-Muíño, I Segura-Jiménez, N Maldonado-Fernández, JA Ferrón, V García-Róspide and P Palma
    Citation: BMC Gastroenterology 2010 10:59
  28. Mannoproteins are yeast cell wall componend, and rich in mannose. The use of foods rich in mannose as carbohydrate, could have a bioprotective effect against entrobacteria intestinal infection. Nothing is know...

    Authors: Sinforiano J Posadas, Victor Caz, Isabel Caballero, Emilio Cendejas, Immaculada Quilez, Carlota Largo, Marcos Elvira and Enrique De Miguel
    Citation: BMC Gastroenterology 2010 10:58
  29. Gilbert syndrome is caused by defects in bilirubin UDP-glucuronosyltransferase (UGT1A1). The most common variation believed to be involved is A(TA)7TAA. Although several polymorphisms have been found to link w...

    Authors: Katsuyuki Matsui, Yoshihiro Maruo, Hiroshi Sato and Yoshihiro Takeuchi
    Citation: BMC Gastroenterology 2010 10:57
  30. Fatty liver is known to be linked with insulin resistance, alcohol intake, diabetes and obesity. Biopsy and even scan-assessed fatty liver are not always feasible in clinical practice. This report evaluates th...

    Authors: Beverley Balkau, Celine Lange, Sylviane Vol, Frederic Fumeron and Fabrice Bonnet
    Citation: BMC Gastroenterology 2010 10:56
  31. Abnormalities of cell cycle regulators are common features in human cancers, and several of these factors are associated with the early development of gastric cancers. However, recent studies have shown that g...

    Authors: Tamotsu Sugai, Mitsunori Tsukahara, Masaki Endoh, Yoshihiro Shioi, Noriko Takebe, Yoshiharu Mue, Hiroo Matsushita, Minoru Toyota and Kazuyuki Suzuki
    Citation: BMC Gastroenterology 2010 10:55
  32. Reflux esophagitis (RE) is increasing in prevalence in China. There are very few studies on the prevalence and factors related to RE in patients with chronic liver diseases. The aims of this study were to dete...

    Authors: Bing Li, Bin Zhang, Jun Wei Ma, Peng Li, Lei Li, Yun Ming Song and Hui Guo Ding
    Citation: BMC Gastroenterology 2010 10:54
  33. Non invasive approaches will likely be increasing utilized to assess liver fibrosis. This work provides a new non invasive index to predict liver fibrosis induced in mice.

    Authors: Mohamed H Hessien, Ismaiel M El-Sharkawi, Ahmed A El-Barbary, Doha M El-Beltagy and Ned Snyder
    Citation: BMC Gastroenterology 2010 10:53
  34. Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH). Another member of the toll-like receptor family, TLR...

    Authors: Chantal A Rivera, LaTausha Gaskin, Monique Allman, Jia Pang, Kristen Brady, Patrick Adegboyega and Kevin Pruitt
    Citation: BMC Gastroenterology 2010 10:52
  35. Metabolic syndrome (MetS) is composed of cardiovascular risk factors including insulin resistance, obesity, dyslipidemia, and hypertension. Most of the components of MetS have been linked to the development of...

    Authors: Chiu-Shong Liu, Hua-Shui Hsu, Chia-Ing Li, Chia-Ing Jan, Tsai-Chung Li, Wen-Yuan Lin, Tsann Lin, Ya-Chien Chen, Cheng-Chun Lee and Cheng-Chieh Lin
    Citation: BMC Gastroenterology 2010 10:51
  36. Antibodies against gonadotropin-releasing hormone (GnRH) and gastrointestinal dysmotility have been found after treatment with GnRH analogues. The aim of this study was to examine the presence of such antibodi...

    Authors: Bodil Ohlsson, Eva Ekblad, Béla Veress, Agneta Montgomery and Sabina Janciauskiene
    Citation: BMC Gastroenterology 2010 10:48
  37. Colorectal cancer (CRC) is the second most prevalent type of cancer in Europe. Early detection and removal of CRC or its precursor lesions by population screening can reduce mortality. Colonoscopy and computed...

    Authors: Thomas R de Wijkerslooth, Margriet C de Haan, Esther M Stoop, Marije Deutekom, Paul Fockens, Patrick MM Bossuyt, Maarten Thomeer, Marjolein van Ballegooijen, Marie-Louise Essink-Bot, Monique E van Leerdam, Ernst J Kuipers, Evelien Dekker and Jaap Stoker
    Citation: BMC Gastroenterology 2010 10:47
  38. We previously reported a highly sensitive method for serum human telomerase reverse transcriptase (hTERT) mRNA for hepatocellular carcinoma (HCC). α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) are go...

    Authors: Norimasa Miura, Yukio Osaki, Miki Nagashima, Michimori Kohno, Kensho Yorozu, Kohei Shomori, Takamasa Kanbe, Kenji Oyama, Yukihiro Kishimoto, Shigeo Maruyama, Eijiro Noma, Yutaka Horie, Masatoshi Kudo, Seigo Sakaguchi, Yasuaki Hirooka, Hisao Ito…
    Citation: BMC Gastroenterology 2010 10:46
  39. Since population screening has the potential to reduce mortality from rectal cancer (RC), novel methods with improved cost-effectiveness warrant consideration. In a previous pilot study, we found that the rapi...

    Authors: Alberto Vannelli, Luigi Battaglia, Elia Poiasina and Ermanno Leo
    Citation: BMC Gastroenterology 2010 10:45
  40. Gene transfer to the gastrointestinal (GI) mucosa is a therapeutic strategy which could prove particularly advantageous for treatment of various hereditary and acquired intestinal disorders, including inflamma...

    Authors: Hiroshi Matsumoto, Takahiro Kimura, Kazunori Haga, Noriyuki Kasahara, Peter Anton and Ian McGowan
    Citation: BMC Gastroenterology 2010 10:44
  41. Liver injury due to dengue viral infection is not uncommon. Acute liver injury is a severe complicating factor in dengue, predisposing to life-threatening hemorrhage, Disseminated Intravascular Coagulation (DI...

    Authors: Om Parkash, Aysha Almas, SM Wasim Jafri, Saeed Hamid, Jaweed Akhtar and Hasnain Alishah
    Citation: BMC Gastroenterology 2010 10:43
  42. Hepatic ischemia-reperfusion injury (I/Ri) is a serious complication occurring during liver surgery that may lead to liver failure. Hepatic I/Ri induces formation of reactive oxygen species, hepatocyte apoptos...

    Authors: Yunwei Wei, Ping Chen, Marco de Bruyn, Weihui Zhang, Edwin Bremer and Wijnand Helfrich
    Citation: BMC Gastroenterology 2010 10:42

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