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  1. Peroxisome proliferators-activated receptor alpha (PPARα) activation modulates cholesterol metabolism and suppresses bile acid synthesis. This study aims to evaluate the effect of short-term administration of ...

    Authors: Mehmet Cindoruk, Mustafa Kerem, Tarkan Karakan, Bulent Salman, Okan Akin, Murat Alper, Ozlem Erdem and Selahattin Ünal
    Citation: BMC Gastroenterology 2007 7:44
  2. Patients with malignant tumours of the upper gastrointestinal tract tumours exhibit important alarm symptoms such as dysphagia that warrant clinical investigations. An endoscopic examination of the upper gastr...

    Authors: Nafees A Qureshi, Michael T Hallissey and John W Fielding
    Citation: BMC Gastroenterology 2007 7:43
  3. Gastroesophageal reflux disease is a common and chronic disorder but long term, prospective studies of the fate of patients seeking medical advice are scarce. This is especially prominent when looking at non-e...

    Authors: Siavosh Nasseri-Moghaddam, Hadi Razjouyan, Seyed Maysam Alimohamadi, Mansoureh Mamarabadi, Mohamad-Hamed Ghotbi, Pardis Mostajabi, Amir-Ali Sohrabpour, Masoud Sotoudeh, Behnoush Abedi, Azadeh Mofid, Mehdi Nouraie, Shahnaz Tofangchiha and Reza Malekzadeh
    Citation: BMC Gastroenterology 2007 7:42
  4. Fatty liver disease is characterized by the accumulation of fat vacuoles inside of the hepatocytes. Non alcoholic fatty liver is associated with obesity, type 2 diabetes, dyslipemia, the intake of certain drug...

    Authors: Llorenç Caballería, Ma Antonia Auladell, Pere Torán, Dolores Miranda, Jesús Aznar, Guillem Pera, Dolors Gil, Laura Muñoz, Jaume Planas, Santiago Canut, Jesús Bernad, Josep Aubà, Gregorio Pizarro, Miren Maite Aizpurua, Anna Altaba and Albert Tibau
    Citation: BMC Gastroenterology 2007 7:41
  5. FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients with chronic hepatitis C (CHC).

    Authors: Thierry Poynard, Rachel Morra, Philippe Halfon, Laurent Castera, Vlad Ratziu, Françoise Imbert-Bismut, Sylvie Naveau, Dominique Thabut, Didier Lebrec, Fabien Zoulim, Marc Bourliere, Patrice Cacoub, Djamila Messous, Mona Munteanu and Victor de Ledinghen
    Citation: BMC Gastroenterology 2007 7:40
  6. Interest in psychological factors in patients with inflammatory bowel disease (IBD) has increased in recent years. It has even been proposed that treating psychological co-morbidities with antidepressants may ...

    Authors: Antonina A Mikocka-Walus, Deborah A Turnbull, Nicole T Moulding, Ian G Wilson, Jane M Andrews and Gerald J Holtmann
    Citation: BMC Gastroenterology 2007 7:38
  7. Colonic diverticular disease is a bothersome condition with an unresolved pathogenesis. It is unknown whether a neuroepithelial dysfunction is present. The aim of the study was two-fold; (1) to investigate col...

    Authors: Philip S Osbak, Niels Bindslev, Steen S Poulsen, Nicolai Kaltoft, Maria C Tilotta and Mark B Hansen
    Citation: BMC Gastroenterology 2007 7:37
  8. The prebiotic potential of lactulose is well established and preclinical studies demonstrated a protective effect of lactulose in murine models of colitis. The aim of the present study was to investigate the c...

    Authors: Anne Hafer, Sigrid Krämer, Swantje Duncker, Martin Krüger, Michael P Manns and Stephan C Bischoff
    Citation: BMC Gastroenterology 2007 7:36
  9. Epidemiological data on characteristics of patients undergoing open or laparoscopic cholecystectomy are limited. In this register study we examined characteristics and mortality of patients who underwent chole...

    Authors: Mats Rosenmüller, Markku M Haapamäki, Pär Nordin, Hans Stenlund and Erik Nilsson
    Citation: BMC Gastroenterology 2007 7:35
  10. Portal vein thrombosis (PVT) is increasingly frequently being diagnosed, but systematic descriptions of the natural history and clinical handling of the condition are sparse. The aim of this retrospective stud...

    Authors: Kirstine K Sogaard, Lone B Astrup, Hendrik Vilstrup and Henning Gronbaek
    Citation: BMC Gastroenterology 2007 7:34
  11. The development of new ultrasound contrast agents (UCAs) has become one of the most promising fields in ultrasound medicine. This paper evaluates a new self-made contrast agent enhancement effect developed to ...

    Authors: Li Zhang, Yun-You Duan, Ji-Kai Yin, Ji-Hong Cui, Yong Zhang and Tie-Sheng Cao
    Citation: BMC Gastroenterology 2007 7:32
  12. Rifabutin has been found to be effective in multi-resistant patients after various treatment cycles for Helicobacter pylori (HP) infection, but it has not been analysed as a second-line treatment. Therefore, w...

    Authors: José M Navarro-Jarabo, Nuria Fernández, Francisca L Sousa, Encarnación Cabrera, Manuel Castro, Luz M Ramírez, Robin Rivera, Esther Ubiña, Francisco Vera, Isabel Méndez, Francisco Rivas-Ruiz, José L Moreno and Emilio Perea-Milla
    Citation: BMC Gastroenterology 2007 7:31
  13. Whilst the public now have access to mortality & morbidity data for cardiothoracic surgeons, such "quality" data for endoscopy are not generally available. We studied endoscopists' attitudes to and the practic...

    Authors: Sarah A Hearnshaw, Helena M Maddock, David Nylander and Martin I Prince
    Citation: BMC Gastroenterology 2007 7:30
  14. Gastrointestinal cancer is the first leading cause of cancer related deaths in men and the second among women in Iran. An investigation was carried out to examine anxiety and depression in this group of patien...

    Authors: Azadeh Tavoli, Mohammad Ali Mohagheghi, Ali Montazeri, Rasool Roshan, Zahra Tavoli and Sepideh Omidvari
    Citation: BMC Gastroenterology 2007 7:28
  15. Anomalous biliary opening especially the presence of the ampulla of Vater in the duodenal bulb is a very rare phenomenon. We report clinical implications, laboratory and ERCP findings and also therapeutic appr...

    Authors: Selcuk Disibeyaz, Erkan Parlak, Bahattin Cicek, Cem Cengiz, Sedef O Kuran, Dilek Oguz, Hakan Güzel and Burhan Sahin
    Citation: BMC Gastroenterology 2007 7:26
  16. Esophageal reflux and Barrett's esophagus represent two major risk factors for the development of esophageal adenocarcinoma. Previous studies have shown that brief exposure of the Barrett's-associated adenocar...

    Authors: Ying Hao, Sumita Sood, George Triadafilopoulos, Jong Hyeok Kim, Zheng Wang, Peyman Sahbaie, M Bishr Omary and Anson W Lowe
    Citation: BMC Gastroenterology 2007 7:24
  17. It is well-known that nonsteroidal anti-inflammatory drugs (NSAIDs) can cause damage to the small bowel associated with disruption of mucosal barrier function. In healthy human volunteers, we showed previously...

    Authors: Martijn JL Bours, Hilde J Bos, Jon B Meddings, Robert-Jan M Brummer, Piet A van den Brandt and Pieter C Dagnelie
    Citation: BMC Gastroenterology 2007 7:23
  18. Portal-mesenteric vein thrombosis, pylephlebitis and liver abscesses are rare complications of inflammatory bowel disease (IBD). The purpose of this case report is to relate an unusual presentation of CD in or...

    Authors: Mariam Aguas, Guillermo Bastida, Pilar Nos, Belen Beltrán, Jose Luis Grueso and Julio Grueso
    Citation: BMC Gastroenterology 2007 7:22
  19. Hepatitis C virus (HCV) infection is associated with high percentage of chronicity which implies the ability of the virus to evade or modulate host cell immune system. Modulation of chemokines, such as RANTES ...

    Authors: Anna Ruggieri, Marina Franco, Ilaria Gatto, Ajit Kumar and Maria Rapicetta
    Citation: BMC Gastroenterology 2007 7:21
  20. Non-adherence to drug therapy is common in Inflammatory Bowel Disease (IBD). Patients' beliefs about treatment have an important influence on adherence. An in-depth understanding of this area is, therefore, im...

    Authors: Nicola J Hall, Gregory P Rubin, APS Hungin and Audrey Dougall
    Citation: BMC Gastroenterology 2007 7:20
  21. Many factors impacting cecal intubation rates have been examined in detail; however, little information exists regarding the effect of the timing of the procedure. We sought to examine any difference in cecal ...

    Authors: Christopher D Wells, Russell I Heigh, Virender K Sharma, Michael D Crowell, Suryakanth R Gurudu, Jonathan A Leighton, Nora Mattek and David E Fleischer
    Citation: BMC Gastroenterology 2007 7:19
  22. Gastrojejunostomy (GJJ) is the most commonly used palliative treatment modality for malignant gastric outlet obstruction. Recently, stent placement has been introduced as an alternative treatment. We reviewed ...

    Authors: Suzanne M Jeurnink, Casper HJ van Eijck, Ewout W Steyerberg, Ernst J Kuipers and Peter D Siersema
    Citation: BMC Gastroenterology 2007 7:18
  23. The role of leptin in the course of liver disease due to chronic viral hepatitis (CVH) remains controversial. Our aims were to investigate the relationship between serum leptin concentrations and the severity ...

    Authors: Spilios Manolakopoulos, Sotirios Bethanis, Charis Liapi, Fotini Stripeli, Pantelis Sklavos, Alexandra Margeli, Aggeliki Christidou, Aggeliki Katsanika, Evangellos Vogiatzakis, Dimitrios Tzourmakliotis and Stamatios Theocharis
    Citation: BMC Gastroenterology 2007 7:17
  24. The aim of this study was to develop and psychometrically test a short, patient-reported questionnaire to be used in clinical practice for patients with Irritable Bowel Syndrome (IBS). The Visual Analogue Scal...

    Authors: Mariette Bengtsson, Bodil Ohlsson and Kerstin Ulander
    Citation: BMC Gastroenterology 2007 7:16
  25. Serum concentration of fetuin A/α2HS-glycoprotein (AHSG) is a good indicator of liver cell function and 1-month mortality in patients with alcoholic liver cirrhosis and liver cancer. We intended to determine w...

    Authors: László Kalabay, László Gráf, Krisztián Vörös, László Jakab, Zsuzsa Benkő, László Telegdy, Béla Fekete, Zoltán Prohászka and George Füst
    Citation: BMC Gastroenterology 2007 7:15
  26. There is consistent evidence that 50% of patients with acute, steroid-resistant flare of ulcerative colitis (UC) may achieve remission and avoid colectomy if treated with cyclosporin (CsA). However, follow-up ...

    Authors: Giovanni C Actis, Maurizio Fadda, Ezio David and Anna Sapino
    Citation: BMC Gastroenterology 2007 7:13
  27. Cystic artery pseudoaneurysm is a rare complication following cholecystitis. Its presentation with upper gastrointestinal hemorrhage (UGIH) is even rarer. Thirteen patients with cystic artery pseudoaneurysm ha...

    Authors: Sundeep S Saluja, Sukanta Ray, Manpreet S Gulati, Sujoy Pal, Peush Sahni and Tushar K Chattopadhyay
    Citation: BMC Gastroenterology 2007 7:12
  28. Few studies have described patients with foregut dysmotility in inflammatory bowel disease. The aim of this case series was to evaluate clinical characteristics of 5 patients with inflammatory bowel disease an...

    Authors: Jón O Kristinsson, Wim PM Hopman, Wim JG Oyen and Joost PH Drenth
    Citation: BMC Gastroenterology 2007 7:11
  29. While the mortality of esophageal surgery has decreased due to technological advancements, there is still a complication rate of about 30%. One of the main complications is the anastomotic leakage associated w...

    Authors: Jens-Gerd Scharf, Giuliano Ramadori, Heinz Becker and Annegret Müller
    Citation: BMC Gastroenterology 2007 7:10
  30. Neonatal hepatitis refers to a heterogeneous group of disorders, caused by many factors including cytomegalovirus infection, revealing similar morphologic changes in the liver of an infant less than 3 months o...

    Authors: Tanju Basarir Ozkan, Resit Mistik, Bunyamin Dikici and Hülya Ozturk Nazlioglu
    Citation: BMC Gastroenterology 2007 7:9
  31. The association between coeliac disease (CD) and neoplasms has been long established, but few data are available about the risk factors. The aim of this paper is to estimate the risk of developing a neoplasm a...

    Authors: Marco Silano, Umberto Volta, Anna Maria Mecchia, Mariarita Dessì, Rita Di Benedetto and Massimo De Vincenzi
    Citation: BMC Gastroenterology 2007 7:8
  32. Glutathione is a tripeptide composed of glutamate, cysteine and glycine, accomplishing a broad range of vital functions. Synthesis of glutathione and cysteine is performed mainly in the liver, whereas most oth...

    Authors: Wilbert HM Peters, Annie van Schaik, Joost H Peters and Harry van Goor
    Citation: BMC Gastroenterology 2007 7:7
  33. Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography and the benefit of its pharmacological treatment is unclear. Although prophylactic use of gabexate for the reductio...

    Authors: Minghua Zheng, Yongping Chen, Xinjun Yang, Ji Li, Youcai Zhang and Qiqiang Zeng
    Citation: BMC Gastroenterology 2007 7:6
  34. The epidemiology of liver disease in patients admitted to emergency rooms is largely unknown. The current study aimed to measure the prevalence of viral hepatitis B and C infection and pathological laboratory ...

    Authors: Stefan Russmann, Emmilia A Dowlatshahi, Gert Printzen, Susanne Habicht, Jürg Reichen and Heinz Zimmermann
    Citation: BMC Gastroenterology 2007 7:5
  35. Bleeding from small bowel neoplasms account for 1–4% of cases of upper gastrointestinal haemorrhage. Renal cell carcinoma constitutes 3% of all adult malignancies and often presents insidiously. Consequently 2...

    Authors: Gareth J Sadler, Mark R Anderson, Mark S Moss and Paul G Wilson
    Citation: BMC Gastroenterology 2007 7:4
  36. Gastroparesis has a number of etiologies. The main ones are secondary to a complication from diabetes mellitus, related to post vagotomy or post gastric surgical resections, or idiopathic when the etiology is ...

    Authors: Savio C Reddymasu, John Bonino and Richard W McCallum
    Citation: BMC Gastroenterology 2007 7:3
  37. Opportunistic invasive fungal infections are increasingly frequent in intensive care patients. Their clinical spectrum goes beyond the patients with malignancies, and for example invasive pulmonary aspergillos...

    Authors: Hélène Prodanovic, Christophe Cracco, Julien Massard, Camille Barrault, Dominique Thabut, Alexandre Duguet, Annick Datry, Jean-Philippe Derenne, Thierry Poynard and Thomas Similowski
    Citation: BMC Gastroenterology 2007 7:2
  38. Sodium retention and ascites are serious clinical problems in cirrhosis. Urodilatin (URO) is a peptide with paracrine effects in decreasing sodium reabsorption in the distal nephron. Our aim was to investigate...

    Authors: Jan Carstens, Henning Grønbæk, Helle K Larsen, Erling B Pedersen and Hendrik Vilstrup
    Citation: BMC Gastroenterology 2007 7:1
  39. One of the rare presentations of superior vena cava syndrome is bleeding of "downhill" esophageal varices (DEV) and different approaches have been used to control it. This is a case report whose DEV was eradic...

    Authors: Hamid Tavakkoli, Mehrnaz Asadi, Mahshid Haghighi and Abbas Esmaeili
    Citation: BMC Gastroenterology 2006 6:43
  40. The genetic basis of tropical calcific pancreatitis (TCP) is different and is explained by mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene. However, mutated SPINK1 does not account for the d...

    Authors: Seema Bhaskar, DN Reddy, Swapna Mahurkar, GV Rao, Lalji Singh and Giriraj R Chandak
    Citation: BMC Gastroenterology 2006 6:42
  41. The urokinase-type (uPA) and tissue-type (tPA) plasminogen activators regulate liver matrix remodelling through the conversion of plasminogen (Plg) to the active protease plasmin. Based on the efficient activa...

    Authors: Kumar Shanmukhappa, Gregg E Sabla, Jay L Degen and Jorge A Bezerra
    Citation: BMC Gastroenterology 2006 6:40

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