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  1. Patients with chronic liver disease frequently suffer from malnutrition, together with a decline in their health-related quality of life.

    Authors: María Teresa García-Rodríguez, María del Carmen Piñón-Villar, Beatriz López-Calviño, Alejandra Otero-Ferreiro, Francisco Suárez-López, Manuel Gómez-Gutiérrez and Salvador Pita-Fernández
    Citation: BMC Gastroenterology 2015 15:6
  2. MicroRNA-21 (miR-21) is an oncogenic microRNA that regulates the expression of multiple cancer-related target genes. miR-21 has been associated with progression of some types of cancer. Metastasis-associated p...

    Authors: Won Kyung Kang, Jin Kwon Lee, Seong Taek Oh, Sung Hak Lee and Chan Kwon Jung
    Citation: BMC Gastroenterology 2015 15:2
  3. Activated hepatic stellate cells are the main source of excessive collagen deposition in liver fibrosis. Here we report the inhibitory effects of the combinational treatment of two natural products, astragalus...

    Authors: Jin Zheng, Li-tian Ma, Qin-you Ren, Lu Li, Yi Zhang, Heng-jun Shi, Yi Liu, Cheng-hua Li, Yong-qi Dou, Shao-dan Li, Hui Zhang and Ming-hui Yang
    Citation: BMC Gastroenterology 2014 14:224
  4. Investigations of genetic alterations and correlations with histology or morphology could provide further insights into colorectal carcinogenesis. Nevertheless, such genetic changes were less investigated in a...

    Authors: Li-Chun Chang, Han-Mo Chiu, Chia-Tung Shun, Jin-Tung Liang, Jaw-Town Lin, Chien-Chuan Chen, Yi-Chia Lee and Ming-Shiang Wu
    Citation: BMC Gastroenterology 2014 14:221
  5. Precise diagnostics of inflammatory bowel disease (IBD) and identification of potentially more aggressive phenotypes of Crohn’s disease (CD) is urgently needed. The aim of our prospective study was to assess t...

    Authors: Darina Kohoutova, Marcela Drahosova, Paula Moravkova, Stanislav Rejchrt and Jan Bures
    Citation: BMC Gastroenterology 2014 14:190
  6. Wireless pH-monitoring is an accurate method for diagnosing adults with gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the use of the Bravo capsule on children investigated for G...

    Authors: Michaela Boström, Ola Thorsson, Ervin Toth and Daniel Agardh
    Citation: BMC Gastroenterology 2014 14:9001
  7. Helicobacter pylori chronic infection is associated with chronic gastritis, peptic ulcer, and gastric cancer. Cytotoxin-associated gene A (cagA)-positive H. pylori strains increase the risk of gastric pathology....

    Authors: Fredy Omar Beltrán-Anaya, Tomás Manuel Poblete, Adolfo Román-Román, Salomón Reyes, José de Sampedro, Oscar Peralta-Zaragoza, Miguel Ángel Rodríguez, Oscar del Moral-Hernández, Berenice Illades-Aguiar and Gloria Fernández-Tilapa
    Citation: BMC Gastroenterology 2014 14:223
  8. Faecal immunochemical tests (FITs) are commonly used in colorectal cancer (CRC) screening. Diagnostic accuracy of FIT differs between males and females. This so far unexplained difference could result in a dis...

    Authors: Sietze T van Turenhout, Frank A Oort, René WM van der Hulst, Arjen P Visscher, Jochim S Terhaar sive Droste, Pieter Scholten, Anneke A Bouman, Gerrit A Meijer, Chris JJ Mulder, Leo GM van Rossum and Veerle MH Coupé
    Citation: BMC Gastroenterology 2014 14:217
  9. Non-adherence to aminosalicylates is observed among 30% to 45% of patients with ulcerative colitis and increases the risk of relapse. The Health Belief Model is a theoretical model that could offer a broader p...

    Authors: Aki Kawakami, Makoto Tanaka, Masakazu Nishigaki, Naoki Yoshimura, Ryoichi Suzuki, Shin Maeda, Reiko Kunisaki and Noriko Yamamoto-Mitani
    Citation: BMC Gastroenterology 2014 14:220
  10. Non-invasive models and methods to substitute liver biopsy in chronic hepatitis B (CHB) patients were investigated but their roles as predictors of significant liver histology for diagnosis of HBeAg-negative C...

    Authors: Surat Praneenararat, Naichaya Chamroonkul, Pimsiri Sripongpun, Samornmas Kanngurn, Roongrueng Jarumanokul and Teerha Piratvisuth
    Citation: BMC Gastroenterology 2014 14:218
  11. HBV and HCV reactivation have been widely reported in patients undergoing immunosuppressive therapy (IT); however, few data are available on the risk of reactivation in patients with psoriasis receiving IT. Th...

    Authors: Filomena Morisco, Maria Guarino, Serena La Bella, Luisa Di Costanzo, Nicola Caporaso, Fabio Ayala and Nicola Balato
    Citation: BMC Gastroenterology 2014 14:214
  12. We aimed at assessing the factors that can influence results of the dissemination of an already validated, new generation commercial Point-of-Care Test (POCT) for detecting celiac disease (CD), in the Mediterr...

    Authors: Stefano Costa, Luca Astarita, Mongi Ben-Hariz, Giovanni Currò, Jernej Dolinsek, Aydan Kansu, Giuseppe Magazzu’, Stefania Marvaso, Dusanka Micetic-Turku, Salvatore Pellegrino, Giuseppe Primavera, Pasqualino Rossi, Andrea Smarrazzo, Francesca Tucci, Carmela Arcidiaco and Luigi Greco
    Citation: BMC Gastroenterology 2014 14:219
  13. Functional gastrointestinal disorders (FGID) are defined by a combination of chronic or recurrent gastrointestinal symptoms. Prevalence rates of FGID are high. Symptoms are associated with distress, and suffer...

    Authors: Charlotte Markert, Kerstin Suarez-Hitz, Ulrike Ehlert and Urs M Nater
    Citation: BMC Gastroenterology 2014 14:215
  14. Obesity and related metabolic abnormalities, including excess oxidative stress and chronic inflammation, are associated with colorectal carcinogenesis. Astaxanthin, a xanthophyll carotenoid found in aquatic an...

    Authors: Takahiro Kochi, Masahito Shimizu, Takafumi Sumi, Masaya Kubota, Yohei Shirakami, Takuji Tanaka and Hisataka Moriwaki
    Citation: BMC Gastroenterology 2014 14:212
  15. Early life exposures may modify risk of inflammatory bowel diseases (IBD; Crohn’s disease (CD), ulcerative colitis (UC)). However, the relationship between early life exposures and natural history of IBD has n...

    Authors: Abra Y Guo, Betsy W Stevens, Robin G Wilson, Caitlin N Russell, Melissa A Cohen, Holly C Sturgeon, Anna Thornton, Cosmas Giallourakis, Hamed Khalili, Deanna D Nguyen, Jenny Sauk, Vijay Yajnik, Ramnik J Xavier and Ashwin N Ananthakrishnan
    Citation: BMC Gastroenterology 2014 14:216
  16. Visceral obesity is often accompanied by non-alcoholic fatty liver disease (NAFLD). Activation of NACHT, LRR and PYD domains-containing proteins (NALPs) may contribute to the release of pro-inflammatory cytoki...

    Authors: Rohini Mehta, Arpan Neupane, Lei Wang, Zachary Goodman, Ancha Baranova and Zobair M Younossi
    Citation: BMC Gastroenterology 2014 14:208
  17. Whether non-alcoholic fatty liver disease (NAFLD) is a risk factor for gallstones remains uncertain. Few longitudinal or cohort studies have been used to identify this relationship. The aim of this study was t...

    Authors: Jia Liu, Haiyan Lin, Chengqi Zhang, Lu Wang, Shuo Wu, Dongzhi Zhang, Fang Tang, Fuzhong Xue and Yanxun Liu
    Citation: BMC Gastroenterology 2014 14:213
  18. Women treated with gonadotropin-releasing hormone (GnRH) analogs may develop enteric neuropathy and dysmotility. Administration of a GnRH analog to rats leads to similar degenerative neuropathy and ganglioneur...

    Authors: Elin Sand, Bodil Roth, Björn Weström, Peter Bonn, Eva Ekblad and Bodil Ohlsson
    Citation: BMC Gastroenterology 2014 14:209
  19. Trends in gastroenteritis-associated mortality are changing over time with development of antibiotic resistant strains of certain pathogens, improved diagnostic methods, and changing healthcare. In 1999, ICD-1...

    Authors: Jyotsna S Jagai, Genee S Smith, Judith E Schmid and Timothy J Wade
    Citation: BMC Gastroenterology 2014 14:211
  20. Upper gastrointestinal bleeding (UGIB) remains a common medical problem worldwide that has significant associated morbidity, mortality, and health care resource use. This study outlines the aetiology, clinical...

    Authors: Olusegun I Alatise, Adeniyi S Aderibigbe, Adewale O Adisa, Olusegun Adekanle, Augustine E Agbakwuru and Anthony O Arigbabu
    Citation: BMC Gastroenterology 2014 14:210
  21. Intestinal capillariasis is one of the common causes of malabsorption in the East. Reports emphasizing the roles of clinical, endoscopic and radiologic findings of intestinal capillariasis are limited.

    Authors: Julajak Limsrivilai, Supot Pongprasobchai, Piyaporn Apisarnthanarak and Sathaporn Manatsathit
    Citation: BMC Gastroenterology 2014 14:207
  22. The pathogenesis of inflammatory bowel disease (IBD) involves interactions between the host genetic susceptibility, intestinal microflora and mucosal immune responses through the pattern recognition receptor. ...

    Authors: Nezha Senhaji, Brehima Diakité, Nadia Serbati, Younes Zaid, Wafaa Badre and Sellama Nadifi
    Citation: BMC Gastroenterology 2014 14:206
  23. The aim of this study was to analyse the risk of uncomplicated peptic ulcer disease (PUD) in a cohort of new users of low-dose acetylsalicylic acid (ASA) for secondary prevention of cardiovascular events in a ...

    Authors: Ana Ruigómez, Saga Johansson, Péter Nagy, Mar Martín-Pérez and Luis A García Rodríguez
    Citation: BMC Gastroenterology 2014 14:205
  24. Efforts to identify cell sources and approaches for cell therapy of liver diseases are ongoing, taking into consideration the limits recognized for adult liver tissue and for other forms of stem cells. In the ...

    Authors: Vincenzo Cardinale, Guido Carpino, Raffaele Gentile, Chiara Napoletano, Hassan Rahimi, Antonio Franchitto, Rossella Semeraro, Marianna Nuti, Paolo Onori, Pasquale Bartolomeo Berloco, Massimo Rossi, Daniela Bosco, Roberto Brunelli, Alice Fraveto, Cristina Napoli, Alessia Torrice…
    Citation: BMC Gastroenterology 2014 14:204
  25. The incidence of early-onset (under 50 years of age) colorectal cancer (CRC) in the Vietnamese has been reported to be quite higher than that in the Japanese. To clarify the differences in genetic alterations ...

    Authors: Tomohiro Miwata, Toru Hiyama, Duc Trong Quach, Huy Minh Le, Ha Ngoc Thi Hua, Shiro Oka, Shinji Tanaka, Koji Arihiro and Kazuaki Chayama
    Citation: BMC Gastroenterology 2014 14:203
  26. Serotonin exhibits a vast repertoire of actions including cell proliferation and differentiation. The effect of serotonin, as an incomplete mitogen, on liver regeneration has recently been unveiled and is medi...

    Authors: Konstantinos N Tzirogiannis, Kalliopi T Kourentzi, Sofia Zyga, Vassiliki Papalimneou, Maria Tsironi, Agni D Grypioti, Ioannis Protopsaltis, Dimitrios Panidis and Georgios I Panoutsopoulos
    Citation: BMC Gastroenterology 2014 14:201
  27. Small bowel angioectasia is reported as the most common cause of bleeding in patients with obscure gastrointestinal bleeding. Although the safety and efficacy of endoscopic treatment have been demonstrated, re...

    Authors: Eiji Sakai, Hiroki Endo, Masataka Taguri, Harunobu Kawamura, Leo Taniguchi, Yasuo Hata, Akiko Ezuka, Hajime Nagase, Takaomi Kessoku, Ken Ishii, Jun Arimoto, Eiji Yamada, Hidenori Ohkubo, Takuma Higurashi, Tomoko Koide, Takashi Nonaka…
    Citation: BMC Gastroenterology 2014 14:200
  28. Gastrointestinal graft–versus-host disease (GvHD) is a potentially life-threatening complication after allogeneic stem cell transplantation (SCT). Since therapeutic options are still limited, a prophylactic ap...

    Authors: Renate Schmelz, Martin Bornhäuser, Johannes Schetelig, Alexander Kiani, Uwe Platzbecker, Uta Schwanebeck, Xina Grählert, Lutz Uharek, Daniela Aust, Gustavo Baretton, Rainer Schwerdtfeger, Jochen Hampe, Roland Greinwald, Ralph Mueller, Gerhard Ehninger and Stephan Miehlke
    Citation: BMC Gastroenterology 2014 14:197
  29. We examined the intrinsic hepatic innervation after partial hepatectomy (PH) in rats and the presence and pattern of neural sprouting in regenerating liver.

    Authors: Apostolos N Kandilis, John Koskinas, Ioannis Vlachos, Spyridon Skaltsas, Despina Karandrea, Petros Karakitsos, Alkistis Pantopoulou, Marina Palaiologou, Nikolaos Nikiteas, Dina G Tiniakos and Despina N Perrea
    Citation: BMC Gastroenterology 2014 14:202
  30. The chronic nature of inflammatory bowel disease leads to considerable impairment on the health related quality of life (HRQOL). The aims of the present study are to validate the mainland Chinese translation o...

    Authors: Junjie Xu, Hui Lin, Xu Feng, Minyue Tang, Jun Shen and Zhihua Ran
    Citation: BMC Gastroenterology 2014 14:199
  31. Cirrhosis is a long-term consequence of chronic hepatic injury with fibrosis. No effective therapy is currently available for decompensated cirrhosis except liver transplantation. Hence, we investigated the ef...

    Authors: Yoon Ok Jang, Moon Young Kim, Mee Yon Cho, Soon Koo Baik, Youn Zoo Cho and Sang Ok Kwon
    Citation: BMC Gastroenterology 2014 14:198
  32. Nonalcoholic fatty liver disease (NAFLD) is a risk factor for hepatocellular carcinoma (HCC), but the association between a high-fat diet (HFD) and HCC is not fully understood. In this study, we investigated w...

    Authors: Xiao-Yan Duan, Qin Pan, Shi-Yan Yan, Wen-Jin Ding, Jian-Gao Fan and Liang Qiao
    Citation: BMC Gastroenterology 2014 14:195
  33. Data on the quality of colonoscopies in populations with rising colorectal cancer (CRC) incidence is scarce. We aimed to calculate the adenoma detection rates (ADR), and assess the quality of colonoscopies in ...

    Authors: Alireza Delavari, Faraz Bishehsari, Hamideh Salimzadeh, Pejman Khosravi, Farnaz Delavari, Siavosh Nasseri-Moghaddam, Shahin Merat, Reza Ansari, Homayoon Vahedi, Bijan Shahbazkhani, Mehdi Saberifiroozi, Masoud Sotoudeh and Reza Malekzadeh
    Citation: BMC Gastroenterology 2014 14:196
  34. Celiac disease is a multiform, challenging condition characterized by extremely variable features. Our goal was to define clinical, serological and histopathological findings in a large cohort of celiacs diagn...

    Authors: Umberto Volta, Giacomo Caio, Vincenzo Stanghellini and Roberto De Giorgio
    Citation: BMC Gastroenterology 2014 14:194
  35. Osteopontin (OPN) is a pro-inflammatory cytokine which is expressed in various tissues. It participates in the bone remodeling process and stimulates bone resorption by osteoclasts. It is also a core protein o...

    Authors: Sukhontip Klahan, Chun-Nan Kuo, Shu-Chen Chien, Yea-Wen Lin, Chun-Yi Lin, Chia-Hsien Lin, Wei-Chiao Chang, Ching-I Lin, Kuo-Sheng Hung and Wei-Pin Chang
    Citation: BMC Gastroenterology 2014 14:192
  36. Data are accumulating that emphasize the important role of the intestinal barrier and intestinal permeability for health and disease. However, these terms are poorly defined, their assessment is a matter of de...

    Authors: Stephan C Bischoff, Giovanni Barbara, Wim Buurman, Theo Ockhuizen, Jörg-Dieter Schulzke, Matteo Serino, Herbert Tilg, Alastair Watson and Jerry M Wells
    Citation: BMC Gastroenterology 2014 14:189
  37. The γ-aminobutyric acid type B-receptor agonist lesogaberan (AZD3355) has been developed for use in patients with gastroesophageal reflux disease (GERD) symptoms despite proton pump inhibitor (PPI) therapy (pa...

    Authors: Philip B Miner Jr, Debra G Silberg, Magnus Ruth, Frank Miller and John Pandolfino
    Citation: BMC Gastroenterology 2014 14:188
  38. Autochthonous hepatitis E has been observed with growing incidence in industrialized countries. Hepatitis E virus infection causes an acute hepatitis with spontaneous resolution in the majority of cases. Howev...

    Authors: Marcial Sebode, Sven Pischke, Marc Lütgehetmann, Susanne Polywka, Alexander Quaas, Ansgar W Lohse and Henning Wege
    Citation: BMC Gastroenterology 2014 14:191
  39. The serological diagnosis of celiac disease (CD) often relies on the presence of anti-tissue transglutaminase (tTG) IgA autoantibodies. Patients suffering from selective IgA deficiency (IgAD) are often not awa...

    Authors: Francoise Bienvenu, Silvia I Anghel, Cécile Besson Duvanel, Julien Guillemaud, Lorna Garnier, Florian Renosi, Alain Lachaux and Jacques Bienvenu
    Citation: BMC Gastroenterology 2014 14:186
  40. Metabolic factors have been reported to increase the prevalence of colorectal adenomas, however, whether metabolic factors might also accelerate the recurrence after removal of adenomas has not yet been discus...

    Authors: Leo Taniguchi, Takuma Higurashi, Takashi Uchiyama, Yoshinobu Kondo, Eri Uchida, Shiori Uchiyama, Fumitake Jono, Jun Hamanaka, Hitoshi Kuriyama, Yasuo Hata, Hiroki Endo, Hirokazu Takahashi, Hajime Nagase, Nobuyuki Matsuhashi and Atsushi Nakajima
    Citation: BMC Gastroenterology 2014 14:187
  41. Children with cyclic vomiting syndrome (CVS) have a high degree of maternal inheritance of functional gastrointestinal and neurological disorders. CVS in children is also associated with an increased prevalenc...

    Authors: Thangam Venkatesan, Essam A Zaki, Nilay Kumar, Jyotirmoy Sengupta, Muhammad Ali, Baber Malik, Aniko Szabo, Miranda AL van Tilburg and Richard G Boles
    Citation: BMC Gastroenterology 2014 14:181
  42. Fibromyalgia Syndrome (FMS) is a frequent comorbidity in Irritable Bowel Syndrome (IBS) patients with a higher functional bowel disorder severity index (FBDSI). We tested the possibility that mild to severe IB...

    Authors: Fabrizio Tremolaterra, Serena Gallotta, Yvonne Morra, Ennio Lubrano, Carolina Ciacci and Paola Iovino
    Citation: BMC Gastroenterology 2014 14:9002
  43. Hepatic encephalopathy (HE) represents a significant burden to the healthcare system. The aim of this study was to determine factors influencing the hospital length of stay among patients hospitalized with HE.

    Authors: Valérie Martel-Laferrière, Caitlin Homberger, Kian Bichoupan and Douglas T Dieterich
    Citation: BMC Gastroenterology 2014 14:185
  44. The treatment of iron deficiency anemia in children with inflammatory bowel disease is a particular challenge and often insufficient. Absorption of orally given iron may be impaired by intestinal inflammation ...

    Authors: Martin W Laass, Simon Straub, Suki Chainey, Garth Virgin and Timothy Cushway
    Citation: BMC Gastroenterology 2014 14:184
  45. Despite strong recommendations for colorectal cancer (CRC) screening, participation rates are low. Understanding factors that affect screening choices is essential to developing future screening strategies. Th...

    Authors: Andreas Adler, Sebastian Geiger, Anne Keil, Harald Bias, Philipp Schatz, Theo deVos, Jens Dhein, Mathias Zimmermann, Rudolf Tauber and Bertram Wiedenmann
    Citation: BMC Gastroenterology 2014 14:183
  46. Helicobacter pylori (HP) and Epstein-Barr virus (EBV) have been associated with cancer development. We evaluated the prevalence of HP, HP CagA + and EBV infection in gastric cancer (GC) samples from adults and i...

    Authors: Carolina Rosal Teixeira de Souza, Kátia Soares de Oliveira, Jefferson José Sodré Ferraz, Mariana Ferreira Leal, Danielle Queiroz Calcagno, Aline Damasceno Seabra, André Salim Khayat, Raquel Carvalho Montenegro, Ana Paula Negreiros Nunes Alves, Paulo Pimentel Assumpção, Marília Cardoso Smith and Rommel Rodríguez Burbano
    Citation: BMC Gastroenterology 2014 14:179
  47. Gastroesophageal reflux disease (GERD) is the most common digestive disease, affecting one third of the world’s population. The minimally invasive endoscopic Stretta procedure is being increasingly used as an ...

    Authors: Wei-Tao Liang, Zhong-Gao Wang, Feng Wang, Yue Yang, Zhi-Wei Hu, Jian-Jun Liu, Guang-Chang Zhu, Chao Zhang and Ji-Min Wu
    Citation: BMC Gastroenterology 2014 14:178

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