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  1. Most complications after pancreaticoduodenectomy (PD) were relation to pancreaticoenterostomy. We improved a new method of pancreaticoenterostomy that included the continuous suturing of the jejunum and the st...

    Authors: Guoliang Yao, Yonggang Fan and Jingming Zhai
    Citation: BMC Gastroenterology 2016 16:69
  2. Current knowledge suggests that small intestinal overgrowth participates in the pathogenesis of irritable bowel syndrome. It is questionable if this association is modulated by intake of proton pump inhibitors...

    Authors: Evangelos J. Giamarellos-Bourboulis, Emmanouel Pyleris, Charalambos Barbatzas, Aikaterini Pistiki and Mark Pimentel
    Citation: BMC Gastroenterology 2016 16:67
  3. Ulcerative colitis is a lifelong, immunologically mediated disease. Direct-acting antivirals (DAAs) are now available for the treatment of chronic hepatitis C virus (HCV) infection. An interferon-free regimen ...

    Authors: Yuki Ohta, Tatsuo Kanda, Tatsuro Katsuno, Shin Yasui, Yuki Haga, Reina Sasaki, Masato Nakamura, Shuang Wu, Shingo Nakamoto, Makoto Arai and Osamu Yokosuka
    Citation: BMC Gastroenterology 2016 16:66
  4. Obstructive jaundice has been reported to influence liver elasticity, independent of liver fibrosis. The aim of our prospective study was to evaluate the changes in liver elasticity, before and after biliary d...

    Authors: Kimitoshi Kubo, Hiroshi Kawakami, Masaki Kuwatani, Mutsumi Nishida, Kazumichi Kawakubo, Shuhei Kawahata, Yoko Taya, Yoshimasa Kubota, Toraji Amano, Hiroki Shirato and Naoya Sakamoto
    Citation: BMC Gastroenterology 2016 16:65

    The Erratum to this article has been published in BMC Gastroenterology 2016 16:116

  5. High-quality bowel preparation is necessary for colonoscopy. A few studies have been conducted to investigate improvement in bowel preparation quality through patient education. However, the effect of patient ...

    Authors: Jin-Seok Park, Min Su Kim, HyungKil Kim, Shin Il Kim, Chun Ho Shin, Hyun Jung Lee, Won Seop Lee and Soyoung Moon
    Citation: BMC Gastroenterology 2016 16:64
  6. Colorectal cancer (CRC) is the fourth leading cause of cancer-related death in Europe and the United States. Detecting the disease at an early stage improves outcomes. Risk prediction models which combine mult...

    Authors: Tom G. S. Williams, Joaquín Cubiella, Simon J. Griffin, Fiona M. Walter and Juliet A. Usher-Smith
    Citation: BMC Gastroenterology 2016 16:63
  7. Irritable bowel syndrome (IBS) is one of the most common functional gastroenterological diseases, affecting 11.2 % of people worldwide. Previous studies have shown that probiotic treatment may benefit IBS pati...

    Authors: Yan Zhang, Lixiang Li, Chuanguo Guo, Dan Mu, Bingcheng Feng, Xiuli Zuo and Yanqing Li
    Citation: BMC Gastroenterology 2016 16:62
  8. The incidence of hepatocellular carcinoma with nonalcoholic steatohepatitis is increasing, and its clinicopathological features are well established. Several animal models of nonalcoholic steatohepatitis have ...

    Authors: Norihiro Kishida, Sachiko Matsuda, Osamu Itano, Masahiro Shinoda, Minoru Kitago, Hiroshi Yagi, Yuta Abe, Taizo Hibi, Yohei Masugi, Koichi Aiura, Michiie Sakamoto and Yuko Kitagawa
    Citation: BMC Gastroenterology 2016 16:61
  9. Since the biological function of c-Jun N-terminal kinase (JNK) in gastric cancer remains unclear, we investigated the clinical significance of JNK activation and its association with FOXO1 activation.

    Authors: Youngsun Choi, Jinju Park, Yiseul Choi, Young San Ko, Da-Ae Yu, Younghoon Kim, Jung-Soo Pyo, Bo Gun Jang, Min A. Kim, Woo Ho Kim and Byung Lan Lee
    Citation: BMC Gastroenterology 2016 16:59
  10. Rebamipide is a gastroprotective agent with promising results against gastric damage induced by non-steroidal anti-inflammatory drugs. The present study evaluated if rebamipide protects against naproxen-induce...

    Authors: Thiago Gagliano-Jucá, Ronilson A. Moreno, Tiago Zaminelli, Mauro Napolitano, Antônio Frederico N. Magalhães, Aloísio Carvalhaes, Miriam S. Trevisan, John L. Wallace and Gilberto De Nucci
    Citation: BMC Gastroenterology 2016 16:58
  11. Hexokinase-2 (HK2) and Beta2-adrenergic receptor (Beta2AR) are overexpressed in hepatocellular carcinoma (HCC) tissues and associated with poor prognosis. However, the synergistic effect of HK2 and Beta2AR in ...

    Authors: Zhi-Feng Zhang, Xiao-Sha Feng, He Chen, Zhi-Jun Duan, Li-Xia Wang, Dong Yang, Pi-Xu Liu, Qiu-Ping Zhang, Yan-Ling Jin, Zhi-Gang Sun and Han Liu
    Citation: BMC Gastroenterology 2016 16:57
  12. Endoscopic mucosal resection (EMR) is currently the most used technique for resection of large distal colorectal polyps. However, in large lesions EMR can often only be performed in a piecemeal fashion resulti...

    Authors: Y. Backes, L. M. G. Moons, J. D. van Bergeijk, L. Berk, F. ter Borg, P. C. J. ter Borg, S. G. Elias, J. M. J. Geesing, J. N. Groen, M. Hadithi, J. C. H. Hardwick, M. Kerkhof, M. J. J. Mangen, J. W. A. Straathof, R. Schröder, M. P. Schwartz…
    Citation: BMC Gastroenterology 2016 16:56
  13. Authors: Laxmi Yeruva, Nicole E. Spencer, Manish K. Saraf, Leah Hennings, Anne K. Bowlin, Mario A. Cleves, Kelly Mercer, Sree V. Chintapalli, Kartik Shankar, Roger G. Rank, Thomas M. Badger and Martin J. J. Ronis
    Citation: BMC Gastroenterology 2016 16:55

    The original article was published in BMC Gastroenterology 2016 16:40

  14. Anastomotic stricture is a complex and substantial complication following Roux-en-Y hepaticojejunostomy. Initially, endoscopic and percutaneous approaches are often attempted, but the gold standard remains sur...

    Authors: Yu-long Yang, Cheng Zhang, Ping Wu, Yue-feng Ma, Jing-yi Li, Hong-wei Zhang, Li-jun Shi, Mei-ju Lin and Ying Yu
    Citation: BMC Gastroenterology 2016 16:54
  15. Clinical practice guidelines (CPGs) are formally developed statements that assist users to provide proper health care for a kind of disease and play a significant contribution in healthcare system. This study ...

    Authors: Hongliang Tian, Chao Ding, Jianfeng Gong, Xiaolong Ge, Lynne V. McFarland, Lili Gu, Qiyi Chen, Chunlian Ma, Weiming Zhu, Jieshou Li and Ning Li
    Citation: BMC Gastroenterology 2016 16:52
  16. Transarterial chemoembolization (TACE) and sorafenib are the therapeutic standard for intermediate and advanced stage hepatocellular carcinoma (HCC) patients respectively. High costs with adverse events (AE) o...

    Authors: Wang-De Hsiao, Cheng-Yuan Peng, Po-Heng Chuang, Hsueh-Chou Lai, Ken-Sheng Cheng, Jen-Wei Chou, Yang-Yuan Chen, Cheng-Ju Yu, Chun-Lung Feng, Wen-Pang Su, Sheng-Hung Chen and Jung-Ta Kao
    Citation: BMC Gastroenterology 2016 16:50
  17. Pain and discomfort related to endoscopy sessions can be alleviated by sedation, which minimizes anxiety and allows safe examination. For outpatient endoscopy, reliable short-term sedation without secondary ef...

    Authors: Qiongzhen Li, Qinghe Zhou, Wangpin Xiao and Hongmei Zhou
    Citation: BMC Gastroenterology 2016 16:49
  18. Most patients with gastroesophageal reflux disease experience symptomatic relapse after stopping acid-suppressive medication. The aim of this study was to compare willingness to continue treatment with esomepr...

    Authors: Ekkehard Bayerdörffer, Marc-Andre Bigard, Werner Weiss, Fermín Mearin, Luis Rodrigo, Juan Enrique Dominguez Muñoz, Hennie Grundling, Tore Persson, Lars-Erik Svedberg, Nanna Keeling and Stefan Eklund
    Citation: BMC Gastroenterology 2016 16:48
  19. The relationship between fecal calprotectin (FC) and disease extent in ulcerative colitis (UC) has not been fully elucidated. The aim of this study was to clarify the correlation of FC with disease extent and ...

    Authors: Kousaku Kawashima, Shunji Ishihara, Takafumi Yuki, Nobuhiko Fukuba, Naoki Oshima, Hideaki Kazumori, Hiroki Sonoyama, Noritsugu Yamashita, Yasumasa Tada, Ryusaku Kusunoki, Akihiko Oka, Yoshiyuki Mishima, Ichiro Moriyama and Yoshikazu Kinoshita
    Citation: BMC Gastroenterology 2016 16:47
  20. Incidence of anal carcinoma (AC) is increasing and timely diagnosis is critical for efficient therapy. However, there is a paucity of recent studies addressing clinical symptoms and physical findings of anal c...

    Authors: Matthias Sauter, Georg Keilholz, Helmut Kranzbühler, Norbert Lombriser, Meher Prakash, Stephan R. Vavricka and Benjamin Misselwitz
    Citation: BMC Gastroenterology 2016 16:46
  21. Estimates suggest that only 20 % of HCV-infected patients have been identified and <10 % treated. However, baby boomers (1945-1965) are identified as having a higher prevalence of HCV which has led the Centers...

    Authors: Zobair M. Younossi, Louis L. LaLuna, John J. Santoro, Flavia Mendes, Victor Araya, Natarajan Ravendhran, Lisa Pedicone, Idania Lio, Fatema Nader, Sharon Hunt, Andrei Racila and Maria Stepanova
    Citation: BMC Gastroenterology 2016 16:45
  22. Hepatic artery pseudoaneurysm (HAP) and Hepatic artery dissection are rare vascular complications after living donor liver transplantation (LDLT), which may lead to graft loss and death of the recipients. Conv...

    Authors: Lin Ma, Kefei Chen, Qiang Lu, Wenwu Ling and Yan Luo
    Citation: BMC Gastroenterology 2016 16:44
  23. The routine use of preoperative biliary drainage before pancreaticoduodenectomy (PD) remains controversial. This observational retrospective study compared stented and non-stented patients undergoing PD to ass...

    Authors: Francesca Gavazzi, Cristina Ridolfi, Giovanni Capretti, Maria Rachele Angiolini, Paola Morelli, Erminia Casari, Marco Montorsi and Alessandro Zerbi
    Citation: BMC Gastroenterology 2016 16:43
  24. Polyethylene glycol is commonly used to manage constipation and is available with or without electrolytes. The addition of electrolytes dates back to its initial development as lavage solutions in preparation ...

    Authors: Peter Katelaris, Vasi Naganathan, Ken Liu, George Krassas and John Gullotta
    Citation: BMC Gastroenterology 2016 16:42
  25. Carrageenan is a traditional ingredient that has been widely used in the food industry. In the present study, we propose a hypothesis that carrageenan is a conditional inflammatory agent. When the intestinal t...

    Authors: Wei Wu, Feng Wang, Xin Gao, Tingting Niu, Xiaojuan Zhu, Xiaojun Yan and Haimin Chen
    Citation: BMC Gastroenterology 2016 16:41
  26. Breastfeeding is associated with a variety of positive health outcomes in children and is recommended exclusively for the first 6 months of life; however, 50–70 % of infants in the US are formula-fed. To test ...

    Authors: Laxmi Yeruva, Nicole E. Spencer, Manish K. Saraf, Leah Hennings, Anne K. Bowlin, Mario A. Cleves, Kelly Mercer, Sree V. Chintapalli, Kartik Shankar, Roger G. Rank, Thomas M. Badger and Martin J. J. Ronis
    Citation: BMC Gastroenterology 2016 16:40

    The Erratum to this article has been published in BMC Gastroenterology 2016 16:55

  27. Food sIgG and sIgG4 are highly individually versatile. We put a hypothesis that one of the responsible factors is the presence of gastrointestinal inflammatory diseases. The objectives were: 1. An analysis of whe...

    Authors: Grażyna Czaja-Bulsa, Michał Bulsa and Aneta Gębala
    Citation: BMC Gastroenterology 2016 16:39
  28. Off-treatment durability of nucleoside analogue (NA) therapy in patients with chronic hepatitis B has not been well investigated. In this study we monitored antiviral effect of NA therapy and evaluated off-tre...

    Authors: Naruhiko Nagata, Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Kota Tsuruya, Kazuya Anzai, Koichi Shiraishi and Tetsuya Mine
    Citation: BMC Gastroenterology 2016 16:38
  29. In surgical trials, complex variables such as equipment development and surgeons’ learning curve are involved. The evidence obtained in these trials can thus fluctuate over time. We explored the stability of t...

    Authors: Tomohiko Ukai, Satoru Shikata, Hiromu Takeda, Lauren Dawes, Yoshinori Noguchi, Takeo Nakayama and Yousuke C. Takemura
    Citation: BMC Gastroenterology 2016 16:37
  30. The prevalence of gastro-esophageal reflux disease (GERD) varies widely around the world. This study aimed to investigate the prevalence and risk factors of GERD in a general population of southern India.

    Authors: Hai-Yun Wang, Kondarapassery Balakumaran Leena, Amelie Plymoth, Maria-Pia Hergens, Li Yin, Kotacherry Trivikrama Shenoy and Weimin Ye
    Citation: BMC Gastroenterology 2016 16:36
  31. Most children with Inflammatory Bowel Disease (IBD) are diagnosed between 11 and 16 years of age, commonly presenting with features of typical IBD. Children with onset of gut inflammation under 5 years of age ...

    Authors: Marco Gasparetto, Graziella Guariso, Laura Visona’ Dalla Pozza, Alexander Ross, Robert Heuschkel and Matthias Zilbauer
    Citation: BMC Gastroenterology 2016 16:35
  32. To investigate the efficacy of different probiotic strains, their combinations and forms (alive or lyophilized) in nonalcoholic fatty liver disease (NAFLD) prevention.

    Authors: Nazarii Kobyliak, Tetyana Falalyeyeva, Oleksandr Virchenko, Galyna Mykhalchyshyn, Petro Bodnar, Mykola Spivak, Dmytro Yankovsky, Tetyana Beregova and Lyudmyla Ostapchenko
    Citation: BMC Gastroenterology 2016 16:34
  33. Crigler-Najjar syndrome (CN) is a very rare genetic disorder characterized by an inability to conjugate bilirubin. Contrary to CN type I, patients with CN II exhibit residual capacity to conjugate bilirubin an...

    Authors: Samuel Raimundo Fernandes, Carlos Miguel Moura, Beatriz Rodrigues, Luís Araújo Correia, Helena Cortez-Pinto and José Velosa
    Citation: BMC Gastroenterology 2016 16:33
  34. Hepatitis C virus (HCV) is a common chronic infection that is widely associated with symptoms of fatigue and abdominal pain. The aim of the present study was to determine the prevalence of functional dyspepsia...

    Authors: Hala I. Mohamed, Hamdy A. Mokarib, Zienab M. Saad and Wael M. Abd El Ghany
    Citation: BMC Gastroenterology 2016 16:32
  35. Intestinal bacteria are thought to play a role in the pathogenesis of human inflammatory bowel disease (IBD). We investigated whether oral inoculation with specific intestinal bacteria increased colon inflamma...

    Authors: Matthew P. G. Barnett, Yvonne E. M. Dommels, Christine A. Butts, Shuotun Zhu, Warren C. McNabb and Nicole C. Roy
    Citation: BMC Gastroenterology 2016 16:31
  36. Approximately 2.7 million Americans are chronically infected with hepatitis C virus (HCV). HCV patients with cirrhosis form the largest group of persons at high risk for hepatocellular carcinoma (HCC). Increas...

    Authors: Yachana Kataria, Ryan J. Deaton, Erika Enk, Ming Jin, Milita Petrauskaite, Linlin Dong, Joseph R. Goldenberg, Scott J. Cotler, Donald M. Jensen, Richard B. van Breemen and Peter H. Gann
    Citation: BMC Gastroenterology 2016 16:30
  37. Esophageal variceal bleeding (EVB) is a serious and common complication of cirrhosis. Diabetes mellitus (DM) and chronic kidney disease (CKD) increase mortality in patients with cirrhosis. However, whether coe...

    Authors: Chia-Chi Lung, Zhi-Hong Jian, Jing-Yang Huang and Oswald Ndi Nfor
    Citation: BMC Gastroenterology 2016 16:29
  38. Intestinal microbiota play an important role in maintaining the homeostasis of the host immune system. To analyze the alteration of the intestinal microbial community structure in Korean Crohn’s disease (CD) p...

    Authors: Chang Soo Eun, Min-Jung Kwak, Dong Soo Han, A. Reum Lee, Dong Il Park, Suk-Kyun Yang, Yong Seok Kim and Jihyun F. Kim
    Citation: BMC Gastroenterology 2016 16:28
  39. Non-alcoholic and alcoholic fatty liver disease (NAFLD and AFLD, respectively) are major health problems, as patients with either condition can progress to hepatitis, fibrosis, and cirrhosis. Although histolog...

    Authors: Karuna Rasineni, Daniel D. Penrice, Sathish Kumar Natarajan, Mark A. McNiven, Benita L. McVicker, Kusum K. Kharbanda, Carol A. Casey and Edward N. Harris
    Citation: BMC Gastroenterology 2016 16:27
  40. Approximately 0.2–1 % of children suffers from abdominal migraine (AM). Pathophysiology of AM has not been adequately studied. This study evaluated gastric motility in children with AM.

    Authors: Niranga Manjuri Devanarayana, Shaman Rajindrajith and Marc A. Benninga
    Citation: BMC Gastroenterology 2016 16:26
  41. Hepatocellular carcinoma (HCC) is one of most common and aggressive human malignancies in the world, especially, in eastern Asia, and its mortality is very high at any phase. We want to investigate mechanism o...

    Authors: Shunyan Weng, Liang Zhou, Qing Deng, Jiaxian Wang, Yan Yu, Jianwei Zhu and Yunsheng Yuan
    Citation: BMC Gastroenterology 2016 16:25
  42. Cronkhite-Canada Syndrome (CCS) is a rare non-inherited disease characterized by gastrointestinal polyposis and ectodermal abnormalities, the estimated incidence is about one per million. Recognizing and curin...

    Authors: Ruifeng Zhao, Mely Huang, Omar Banafea, Jinfang Zhao, Ling Cheng, Kaifang Zou and Liangru Zhu
    Citation: BMC Gastroenterology 2016 16:23
  43. L-thyroxine (L-T4) malabsorption is a potential concern in patients with autoimmune atrophic gastritis.

    Authors: Poupak Fallahi, Silvia Martina Ferrari, Ilaria Ruffilli and Alessando Antonelli
    Citation: BMC Gastroenterology 2016 16:22
  44. Actual differences of long term outcome of extrahepatic cholangiocarcinoma according to the location of the tumor have not yet been studied. The aim of this study was to evaluate the prognosis and optimal surg...

    Authors: Keun Soo Ahn, Koo Jeong Kang, Yu Na Kang, Yong Hoon Kim and Tae-Seok Kim
    Citation: BMC Gastroenterology 2016 16:21
  45. Optimal phosphorous control is an important aspect of the care of patients with end-stage renal disease, and phosphate binders are usually needed.

    Authors: Christina Tieu, Roger K. Moreira, Louis M. Wong Kee Song, Shounak Majumder, Konstantinos A. Papadakis and Marie C. Hogan
    Citation: BMC Gastroenterology 2016 16:20

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