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  1. A Phase 2a, open-label study (NCT01724086) was conducted to assess the efficacy and safety of a once-daily, 2-direct-acting-antiviral-agent (2-DAA) combination of simeprevir + TMC647055/ritonavir ± ribavirin a...

    Authors: Stefan Bourgeois, Hans Van Vlierberghe, Christophe Moreno, Hans Orlent, Frederik Nevens, Keikawus Arastéh, Yves Horsmans, Jörn M. Schattenberg, Peter Buggisch, Sven Francque, Leen Vijgen, Thomas N. Kakuda, Eva Hoeben, Donghan Luo, An Vandebosch, Bert Jacquemyn…
    Citation: BMC Gastroenterology 2017 17:26
  2. Little is known about the prognostic impact of cirrhosis on long-term survival of patients with combined hepatocellular-cholangiocarcinoma (cHCC-CC) after hepatic resection. The aim of this study was to elucid...

    Authors: Yan-Ming Zhou, Cheng-Jun Sui, Xiao-Feng Zhang, Bin Li and Jia-Mei Yang
    Citation: BMC Gastroenterology 2017 17:25
  3. Diagnosis of cancer invasion depth is crucial for selecting the optimal treatment strategy in patients with gastrointestinal cancers. We conducted a meta-analysis to determine the utilities of different endosc...

    Authors: Ryu Ishihara, Noriko Matsuura, Noboru Hanaoka, Sachiko Yamamoto, Tomofumi Akasaka, Yoji Takeuchi, Koji Higashino, Noriya Uedo and Hiroyasu Iishi
    Citation: BMC Gastroenterology 2017 17:24
  4. We evaluated the impact of different case definition algorithms on the prevalence of paediatric inflammatory bowel disease (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) and to compare the occurrence ...

    Authors: J. F. Ludvigsson, K. Büsch, O. Olén, J. Askling, K. E. Smedby, A. Ekbom, E. Lindberg and M. Neovius
    Citation: BMC Gastroenterology 2017 17:23
  5. The change of estimated glomerular filtration rate (eGFR) with off-treatment nucleos(t)ide analogues (NA) in chronic hepatitis B patients (CHB) is unclear. This study is aimed to evaluate the off-treatment eGF...

    Authors: Yang-Sheng Lin, Shou-Chuan Shih, Horng-Yuan Wang, Ching-Chung Lin, Chen-Wang Chang and Ming-Jen Chen
    Citation: BMC Gastroenterology 2017 17:22
  6. Uridine (Urd), which has been reported as a major component of RNA, plays an important role in various biological process including neuroprotection, biochemical modulation and glycolysis, although its role in ...

    Authors: Ji Eun Kim, Jun Go, Ji Eun Sung, Hyun Ah Lee, Woo Bin Yun, Jin Tae Hong and Dae Youn Hwang
    Citation: BMC Gastroenterology 2017 17:21
  7. Histological confirmation is needed when the pancreatic lesions is uncertain for neoplastic or nonneoplastic. Current case with multicentric pancreatic carcinomas showing indefinite clinical images was success...

    Authors: Yoshihiro Kishida, Hiroyuki Matsubayashi, Keiko Sasaki, Shinsaku Honda, Sunao Uemura, Katsuhiko Uesaka, Akiko Todaka and Hiroyuki Ono
    Citation: BMC Gastroenterology 2017 17:20
  8. Delayed gastric emptying and bile reflux are common concerns in long-term survivors after Whipple surgery. The study was designed to assess modified retro colic retro gastric gastrojejunostomy in reducing macr...

    Authors: Rohan Chaminda Siriwardana, Rajapaksha Walimuni Mudiyanselage Anuradha Lokubandara, Shivanthi Janaki De Silva Hewavisenthi, Saumya Kumuduni Liyanage, Dona Subani Priyangika Jayatunge and Chandika Anuradha Habarakada Liyanage
    Citation: BMC Gastroenterology 2017 17:19
  9. The Egyptian government introduced the first directly acting antivirals (DAAs) into Egypt through the government funded National Treatment Program. As yet, there has been no investigation into the effects of t...

    Authors: Naglaa F. A. Youssef, Mohamed El Kassas, Amany Farag and Ashley Shepherd
    Citation: BMC Gastroenterology 2017 17:18
  10. We assessed how the diagnosis of Celiac Disease (CD) is made and how the new ESPGHAN guidelines can be applied in children from countries with different resources.

    Authors: Andrea Smarrazzo, Zrinjka Misak, Stefano Costa, Dušanka Mičetić-Turk, Mona Abu-Zekry, Aydan Kansu, Abdelhak Abkari, Karim Bouziane-Nedjadi, Mongi Ben Hariz, Eleftheria Roma, Virtut Velmishi, Maria Legarda Tamara, Thomas Attard, Veselinka Djurisic, Luigi Greco and Giuseppe Magazzù
    Citation: BMC Gastroenterology 2017 17:17
  11. The eradication rate of Helicobacter pylori (H. pylori) with triple therapy which was considered as standard first-line treatment has decreased to 70–85%. The aim of this study is to compare 7-day triple therapy ...

    Authors: Ji Young Chang, Ki-Nam Shim, Chung Hyun Tae, Ko Eun Lee, Jihyun Lee, Kang Hoon Lee, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung and Sung-Ae Jung
    Citation: BMC Gastroenterology 2017 17:16
  12. Telbivudine has been suggested to induce hepatitis B surface antigen (HBsAg) decline to the similar degree as pegylated interferon. We aimed to investigate whether telbivudine could further decrease HBsAg tite...

    Authors: Jihyun An, Young-Suk Lim, Gi-Ae Kim, Seong-bong Han, Wonhee Jeong, Danbi Lee, Ju Hyun Shim, Han Chu Lee and Yung Sang Lee
    Citation: BMC Gastroenterology 2017 17:15
  13. Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of ...

    Authors: Vaios Svolos, Konstantinos Gerasimidis, Elaine Buchanan, Lee Curtis, Vikki Garrick, Jacqueline Hay, Susan Laird, Joanna Munro, Daniel R. Gaya, Richard K. Russell and Richard Hansen
    Citation: BMC Gastroenterology 2017 17:14
  14. The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).

    Authors: Dorota Koziel, Stanislaw Gluszek, Artur Kowalik and Malgorzata Chlopek
    Citation: BMC Gastroenterology 2017 17:13
  15. Activated hepatic stellate cell (HSC) is the main fibrogenic cell type in the injured liver. miRNA plays an important role in activation and proliferation of HSC.

    Authors: Bensong Duan, Jiangfeng Hu, Tongyangzi Zhang, Xu Luo, Yi Zhou, Shun Liu, Liang Zhu, Cheng Wu, Wenxiang Liu, Chao Chen and Hengjun Gao
    Citation: BMC Gastroenterology 2017 17:12
  16. According to Rome criteria, chronic constipation (CC) includes functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C). Some patients do not meet these criteria (No Rome Constipatio...

    Authors: Massimo Bellini, Paolo Usai-Satta, Antonio Bove, Renato Bocchini, Francesca Galeazzi, Edda Battaglia, Pietro Alduini, Elisabetta Buscarini and Gabrio Bassotti
    Citation: BMC Gastroenterology 2017 17:11
  17. Patients with biliary obstruction are at high risk to develop septic complications after endoscopic retrograde cholangiography (ERC). We evaluated the benefits of local application of antimicrobial agents into...

    Authors: Hella Wobser, Agnetha Gunesch and Frank Klebl
    Citation: BMC Gastroenterology 2017 17:10
  18. Liver injury and regeneration involve complicated processes and are affected by various physio-pathological conditions. Surgically, severe liver injury after surgical resection often leads to fatal liver failu...

    Authors: Sanae Haga, Yimin and Michitaka Ozaki
    Citation: BMC Gastroenterology 2017 17:9
  19. The detectable rate of minimal gastric GISTs has continuously increased. While the surveillance and management of GIST <2 cm have been deemed controversial or lack evidence-based approaches.  The aim of the cu...

    Authors: Zhidong Gao, Chao Wang, Qian Xue, Jingtong Wang, Zhanlong Shen, Kewei Jiang, Kai Shen, Bin Liang, Xiaodong Yang, Qiwei Xie, Shan Wang and Yingjiang Ye
    Citation: BMC Gastroenterology 2017 17:8
  20. Limited data are available for advanced colorectal neoplasm in asymptomatic individuals aged 40–49 years. We aimed to identify risk factors and develop a simple prediction model for advanced colorectal neoplas...

    Authors: Yoo Mi Park, Hee Sun Kim, Jae Jun Park, Su Jung Baik, Young Hoon Youn, Jie-Hyun Kim and Hyojin Park
    Citation: BMC Gastroenterology 2017 17:7
  21. Studies have revealed that resistin plays a role as an intrahepatic cytokine with proinflammatory activities. This study investigated the association between serum resistin and fibrosis severity and the possib...

    Authors: Zhongji Meng, Yonghong Zhang, Zhiqiang Wei, Ping Liu, Jian Kang, Yinhua Zhang, Deqiang Ma, Changzheng Ke, Yue Chen, Jie Luo and Zuojiong Gong
    Citation: BMC Gastroenterology 2017 17:6
  22. Risk adjustment is essential for valid comparison of patients’ health outcomes or performances of health care providers. Several risk adjustment methods for liver diseases are commonly used but the optimal app...

    Authors: Yuan Xu, Ning Li, Mingshan Lu, Elijah Dixon, Robert P. Myers, Rachel J. Jolley and Hude Quan
    Citation: BMC Gastroenterology 2017 17:5
  23. Whether gastrointestinal motor and sensory function is primary cause or secondary effect of abnormal body weight is uncertain. Moreover, studies relating continuous postprandial sensations of satiation to meas...

    Authors: Sena Bluemel, Dieter Menne, Gabriella Milos, Oliver Goetze, Michael Fried, Werner Schwizer, Mark Fox and Andreas Steingoetter
    Citation: BMC Gastroenterology 2017 17:4
  24. We aimed to examine the burden of intrahepatic cholangiocarcinoma (ICC) in Thailand and identify the prognostic factors for all-causes of death.

    Authors: Sombat Treeprasertsuk, Kittiyod Poovorawan, Ngamphol Soonthornworasiri, Roongruedee Chaiteerakij, Kessarin Thanapirom, Pisaln Mairiang, Kookwan Sawadpanich, Kanokwan Sonsiri, Varocha Mahachai and Kamthorn Phaosawasdi
    Citation: BMC Gastroenterology 2017 17:3
  25. Individualized therapeutic regimen is a recently intensively pursued approach for targeting diseases, in which the search for biomarkers was considered the first and most important. Thus, the goal of this stud...

    Authors: Yongkuan Cao, Guohu Zhang, Peihong Wang, Jun Zhou, Wei Gan, Yaning Song, Ling Huang, Ya Zhang, Guode Luo, Jiaqing Gong and Lin Zhang
    Citation: BMC Gastroenterology 2017 17:2
  26. Gastric epithelial hyper-proliferation was reported in patients with Helicobacter pylori (H. pylori)–infected gastric mucosa with intestinal metaplasia (IM) changes. In patients with gastric ulcer (GU) and IM, th...

    Authors: Li-Wei Chen, Liang-Che Chang, Chung-Ching Hua, Bor-Jen Hsieh, Shuo-Wei Chen and Rong-Nan Chien
    Citation: BMC Gastroenterology 2017 17:1
  27. Studies examining the association between smoking and the need for surgery in patients with Crohn’s disease and ulcerative colitis have reached inconsistent conclusions. These studies often do not differentiat...

    Authors: M. Ellen Kuenzig, Sang Min Lee, Bertus Eksteen, Cynthia H. Seow, Cheryl Barnabe, Remo Panaccione and Gilaad G. Kaplan
    Citation: BMC Gastroenterology 2016 16:143
  28. Body mass index (BMI), resting energy expenditure (REE) and fasting blood glucose (FBG) are major preoperative assessments of patients’ nutrition and metabolic state. The relations and effects of these indices...

    Authors: Ning Wu, Yongjun Zhu, Dhruba Kadel, Liewen Pang, Gang Chen and Zhiming Chen
    Citation: BMC Gastroenterology 2016 16:142
  29. The association between circulating microRNA-122 (miR-122) and histopathological features of nonalcoholic fatty liver disease (NAFLD) remains unclear.

    Authors: Norio Akuta, Yusuke Kawamura, Fumitaka Suzuki, Satoshi Saitoh, Yasuji Arase, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Yoshiyuki Suzuki, Mariko Kobayashi, Kenji Ikeda and Hiromitsu Kumada
    Citation: BMC Gastroenterology 2016 16:141
  30. The association between stress and peptic ulcers has been questioned since the discovery of helicobacter pylori. This study examined whether high perceived everyday life stress was associated with an increased ri...

    Authors: Ulrik Deding, Linda Ejlskov, Mads Phillip Kofoed Grabas, Berit Jamie Nielsen, Christian Torp-Pedersen and Henrik Bøggild
    Citation: BMC Gastroenterology 2016 16:140
  31. Irritable bowel syndrome (IBS) is more common in patients with ulcerative colitis (UC) than expected. The prevalence of IBS in patients with UC with longstanding disease is not known. We investigated the preva...

    Authors: D. Lundgren, J. Rutegård, V. Eklöf, R. Palmqvist and P. Karling
    Citation: BMC Gastroenterology 2016 16:139
  32. Lactobacilli are non-spore forming, lactic acid producing, gram-positive rods. They are a part of the normal gastrointestinal and genitourinary microbiota and have rarely been reported to be the cause of infec...

    Authors: Muhammed Sherid, Salih Samo, Samian Sulaiman, Husein Husein, Humberto Sifuentes and Subbaramiah Sridhar
    Citation: BMC Gastroenterology 2016 16:138
  33. The use of HCV-positive livers for HCV-positive recipients is becoming more common. Our aim is to evaluate long-term outcomes in liver transplant recipients transplanted with HCV antibody-positive organs.

    Authors: Maria Stepanova, Mehmet Sayiner, Leyla de Avila, Zahra Younoszai, Andrei Racila and Zobair M. Younossi
    Citation: BMC Gastroenterology 2016 16:137
  34. Immunoglobulin A (IgA) antibodies to tissue transglutaminase (tTG) are the serologic test of choice for diagnosing celiac disease (CD). Our aim was to determine if elevated IgA anti-tTG were associated with in...

    Authors: Alberto Rubio-Tapia, Jonas F. Ludvigsson, Rok Seon Choung, Tricia L. Brantner, S. Vincent Rajkumar, Ola Landgren and Joseph A. Murray
    Citation: BMC Gastroenterology 2016 16:136
  35. Toxic liver diseases are mainly caused by drug-induced liver injury (DILI). We assessed incidences and outcomes of DILI including associated factors for mortality.

    Authors: Abhasnee Sobhonslidsuk, Kittiyod Poovorawan, Ngamphol Soonthornworasiri, Wirichada Pan-ngum and Kamthorn Phaosawasdi
    Citation: BMC Gastroenterology 2016 16:135
  36. Proximal or ‘downhill’ esophageal varices are a rare cause of upper gastrointestinal hemorrhage. Unlike the much more common distal esophageal varices, which are most commonly a result of portal hypertension, ...

    Authors: Michael Loudin, Sharon Anderson and Barry Schlansky
    Citation: BMC Gastroenterology 2016 16:134
  37. Adequate bowel preparation is an essential prerequisite for complete mucosal visualization during colonoscopy. Polyethylene glycol (PEG) solutions are commonly used. However the large volume of the solution is...

    Authors: Rupa Banerjee, Hrushikesh Chaudhari, Nirish Shah, Arjunan Saravanan, Manu Tandan and D. Nageshwar Reddy
    Citation: BMC Gastroenterology 2016 16:133
  38. Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites c...

    Authors: Sang Soo Lee, Hyun Ju Min, Ja Yun Choi, Hyun Chin Cho, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Chang Yoon Ha, Hyun Jin Kim, Tae Hyo Kim, Jin Hyun Kim and Ok-Jae Lee
    Citation: BMC Gastroenterology 2016 16:132
  39. A multicentre cohort study was held in Morocco, designed to evaluate the quality of life of cancer patients. The aim of this paper is to report the assessment of the quality of life of early colorectal cancer ...

    Authors: Hind Mrabti, Mounia Amziren, Ibrahim ElGhissassi, Youssef Bensouda, Narjiss Berrada, Halima Abahssain, Saber Boutayeb, Samira El Fakir, Chakib Nejjari, Abdellatif Benider, Nawfel Mellas, Omar El Mesbahi, Maria Bennani, Rachid Bekkali, Ahmed Zidouh and Hassan Errihani
    Citation: BMC Gastroenterology 2016 16:131
  40. Gastric foveolar hyperplastic polyps (GFHPs) are common findings in clinical practice. GFHPs commonly arise in a background of chronic atrophic gastritis, including autoimmune gastritis (type A gastritis), and...

    Authors: Kenichi Yamanaka, Hiroyuki Miyatani, Yukio Yoshida, Takehiro Ishii, Shinichi Asabe, Osamu Takada, Mitsuhiro Nokubi and Hirosato Mashima
    Citation: BMC Gastroenterology 2016 16:130
  41. Alcoholic Hepatitis (AH) is major source of alcohol-related mortality and health care expenditures in the United States. There is insufficient information regarding the role of race and ethnicity on healthcare...

    Authors: Folasade P. May, Vineet S. Rolston, Elliot B. Tapper, Ashwini Lakshmanan, Sammy Saab and Vinay Sundaram
    Citation: BMC Gastroenterology 2016 16:129
  42. This study examines the dual role of Escherichia coli in the course of ulcerative colitis (UC). The intestinal microbiota is considered to play an important role in UC pathogenesis, but how E. coli contributes to...

    Authors: Magdalena Pilarczyk-Zurek, Magdalena Strus, Pawel Adamski and Piotr B. Heczko
    Citation: BMC Gastroenterology 2016 16:128
  43. Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5–2 episodes/year/person and an incidence of 5–100 episodes/1000/week according to seasons and age. There i...

    Authors: Francesca Uberti, Claudio Bardelli, Vera Morsanuto, Sabrina Ghirlanda and Claudio Molinari
    Citation: BMC Gastroenterology 2016 16:127
  44. Faecal calprotectin (FC) is one of the most widely used non-invasive tests for the diagnosis and assessment of Crohn’s disease (CD) activity. Despite this, factors other than disease activity which affect leve...

    Authors: Michael A. Mendall, Derek Chan, Roshani Patel and Devinder Kumar
    Citation: BMC Gastroenterology 2016 16:126
  45. The frequency and clinically important characteristics of incidental (18)F-fluorodeoxyglucose ([18 F]FDG) positron emission tomography (PET) uptake in the gastrointestinal tract (GIT) on PET/CT imaging in adul...

    Authors: Eugenia Shmidt, Vandana Nehra, Val Lowe and Amy S. Oxentenko
    Citation: BMC Gastroenterology 2016 16:125
  46. Cronkhite-Canada syndrome (CCS) is a rare non-inherited disorder, characterized by gastrointestinal polyposis and ectodermal changes. The pathophysiology remains unclear. Treatment with corticosteroids is cons...

    Authors: Kohei Yamakawa, Takuya Yoshino, Kotaro Watanabe, Koichiro Kawano, Akira Kurita, Naomi Matsuzaki, Yoshiaki Yuba and Shujiro Yazumi
    Citation: BMC Gastroenterology 2016 16:123
  47. Authors: Michelle Shui Yee Lau, Peter D. Mooney, William L. White, Victoria Appleby, Sulleman Moreea, Ismail Haythem, Joshua E. Elias, Kiran Bundhoo, Gareth D. Corbett, Liam Wong, Her Hsin Tsai, Simon S. Cross, John M. Hebden, Sami Hoque and David S. Sanders
    Citation: BMC Gastroenterology 2016 16:122

    The original article was published in BMC Gastroenterology 2016 16:115

  48. The rate for upper gastrointestinal (UGI) cancers, and especially the rate for gastric cancer, varies from country to country and from region to region within country. In Turkey, the incidence of gastric cance...

    Authors: Albayrak Fatih, Ozturk Yasin, Dursun Hakan and Albayrak Yavuz
    Citation: BMC Gastroenterology 2016 16:120
  49. Helicobacter pylori (H. pylori) infection and eradication therapy have been known to influence gastric ghrelin and leptin secretion, which may lead to weight gain. However, the exact relationship between plasma g...

    Authors: Chika Kasai, Kazushi Sugimoto, Isao Moritani, Junichiro Tanaka, Yumi Oya, Hidekazu Inoue, Masahiko Tameda, Katsuya Shiraki, Masaaki Ito, Yoshiyuki Takei and Kojiro Takase
    Citation: BMC Gastroenterology 2016 16:119

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