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  1. The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) in...

    Authors: Verima Pereira, Philip Abraham, Sivaramaiah Nallapeta and Anjali Shetty
    Citation: BMC Gastroenterology 2018 18:20
    Content type: Research article Published on:

  2. Peripheral neuropathy is one most common, limiting and invalidating neurological symptom in subjects with hepatitis C virus and mixed cryoglobulinemia. Notably, the medical therapy proposed to eradicate HCV, c...

    Authors: Rita Moretti, Paola Caruso, Matteo Dal Ben, Silvia Gazzin and Claudio Tiribelli
    Citation: BMC Gastroenterology 2018 18:19
    Content type: Research article Published on:

  3. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) predict severity in various diseases. In this study, we evaluated the value of NLR and PLR as prognostic factors in acute pancreatiti...

    Authors: Seung Kook Cho, Saehyun Jung, Kyong Joo Lee and Jae Woo Kim
    Citation: BMC Gastroenterology 2018 18:18
    Content type: Research article Published on:

  5. We present the first description of en bloc endoscopic submucosal dissection (ESD) for total circumferential Barrett’s adenocarcinoma, predominantly of the long-segment Barrett’s esophagus (LSBE), with a 2-year f...

    Authors: Miki Kaneko, Akira Mitoro, Motoyuki Yoshida, Masayoshi Sawai, Yasushi Okura, Masanori Furukawa, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Hideto Kawaratani, Mitsuteru Kitade, Kousuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Shinya Sato…
    Citation: BMC Gastroenterology 2018 18:16
    Content type: Case report Published on:

  6. Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treat...

    Authors: Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro
    Citation: BMC Gastroenterology 2018 18:15
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Gastroenterology 2018 18:36

  7. Endoscopic retrograde cholangiography using a short double-balloon endoscope (DB-ERC) is a promising minimally-invasive method for accessing hepaticojejunostomy (HJ) anastomosis in patients with surgically alt...

    Authors: Sho Mizukawa, Koichiro Tsutsumi, Hironari Kato, Shinichiro Muro, Yutaka Akimoto, Daisuke Uchida, Kazuyuki Matsumoto, Takeshi Tomoda, Shigeru Horiguchi and Hiroyuki Okada
    Citation: BMC Gastroenterology 2018 18:14
    Content type: Research article Published on:

  8. Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The...

    Authors: Abdurahaman Seid, Zemenu Tamir and Wondmagegn Demsiss
    Citation: BMC Gastroenterology 2018 18:13
    Content type: Research article Published on:

  9. Slingshot homolog-1 (SSH1) plays an important role in pathological processes, including in the occurrence and development of tumours. The purpose of this study was to determine whether SSH1 is a key biomarker ...

    Authors: Yusufu Maimaiti, Maimaitiaili Maimaitiming, Yiliang Li, Saifuding Aibibula, Azatijiang Ainiwaer, Aikebaier Aili, Zhenzhu Sun and Kelimu Abudureyimu
    Citation: BMC Gastroenterology 2018 18:12
    Content type: Research article Published on:

  10. Nutrition support is a common means for patients with gastric cancer, especially for those undergoing elective surgery. Recently, enteral immunonutrition (EIN) was increasingly found to be more effective than ...

    Authors: Ying Cheng, Junfeng Zhang, Liwei Zhang, Juan Wu and Zhen Zhan
    Citation: BMC Gastroenterology 2018 18:11
    Content type: Research article Published on:

  11. Different clinical behaviour influences the importance of differentiating focal nodular hyperplasia (FNH) from other focal liver lesions (FLLs). The aim of this study was to compare the efficacy of contrast-en...

    Authors: Tomasz K. Nowicki, Karolina Markiet, Ewa Izycka-Swieszewska, Katarzyna Dziadziuszko, Michal Studniarek and Edyta Szurowska
    Citation: BMC Gastroenterology 2018 18:10
    Content type: Research article Published on:

  12. Mesenteric inflammatory veno-occlusive disease (MIVOD) is difficult to diagnose because of its rarity, nonspecific clinical findings, and frequent confusion with other diseases including inflammatory bowel dis...

    Authors: Yosuke Yamada, Ken Sugimoto, Yashiro Yoshizawa, Yoshifumi Arai, Yoshiro Otsuki, Tomio Arai, Yasuyuki Kobayashi, Yoshihiko Sato and Yoshisuke Hosoda
    Citation: BMC Gastroenterology 2018 18:9
    Content type: Case report Published on:

  13. Gastroesophageal reflux disease (GERD) is a factor that has a significant negative impact on the quality of life (QoL). Vertebral fractures and/or spinal malalignment may influence the frequency of GERD. Howev...

    Authors: Tetsuro Ohba, Shigeto Ebata, Kensuke Koyama and Hirotaka Haro
    Citation: BMC Gastroenterology 2018 18:8
    Content type: Research article Published on:

  14. Colonoscopy plays crucial role in the establishment of the diagnosis, management and follow-up of ulcerative colitis (UC). None of the currently widely used endoscopic scores consider disease extent, and there...

    Authors: Anita Bálint, Klaudia Farkas, Zoltán Szepes, Ferenc Nagy, Mónika Szűcs, László Tiszlavicz, Renáta Bor, Ágnes Milassin, Mariann Rutka, Anna Fábián and Tamás Molnár
    Citation: BMC Gastroenterology 2018 18:7
    Content type: Research article Published on:

  15. The risk of Hepatitis B virus (HBV) reactivation in patients with different hematological malignancy except lymphoma were rarely known before.

    Authors: Chien-Yuan Chen, Feng-Ming Tien, Aristine Cheng, Shang-Yi Huang, Wen-Chien Chou, Ming Yao, Jih-Luh Tang, Hwei-Fang Tien and Wang-Huei Sheng
    Citation: BMC Gastroenterology 2018 18:6
    Content type: Research article Published on:

  16. Ramosetron is a potent and selective serotonin type 3 receptor antagonist. This meta-analysis aimed to analyze the efficacy and safety of ramosetron for irritable bowel syndrome with diarrhea (IBS-D).

    Authors: Qingqing Qi, Yan Zhang, Feixue Chen, Xiuli Zuo and Yanqing Li
    Citation: BMC Gastroenterology 2018 18:5
    Content type: Research article Published on:

  17. Unfortunately, the original article [1] contained an error incorporated during production. A duplicated version of Table 1 was published in place of Table 2. Table 2 has been corrected in the original article ...

    Authors: Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, Hiroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo and Shin Maeda
    Citation: BMC Gastroenterology 2018 18:4
    Content type: Correction Published on:

    The original article was published in BMC Gastroenterology 2017 17:145

  18. Pathogenesis in non-alcoholic steatohepatitis (NASH) involves abnormal cholesterol metabolism and hepatic accumulation of toxic free cholesterol. Apical sodium-dependent bile acid transporter (ASBT) inhibition...

    Authors: Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, Nancy Levin, Lisette Acevedo, Bronislava Gedulin, Andre A. van Vliet, Alejandro Dorenbaum and Melissa Palmer
    Citation: BMC Gastroenterology 2018 18:3
    Content type: Research article Published on:

  19. Elevation of the transcription factor HIF-1 is a prominent mediator of not only processes that accompany hypoxia, but also the tumor microenvironment and tissue regeneration. This study uses mediators of “chem...

    Authors: K. M. DiGuilio, M. C. Valenzano, E. Rybakovsky and J. M. Mullin
    Citation: BMC Gastroenterology 2018 18:2
    Content type: Research article Published on:

  21. It is essential to accurately predict Postoperative liver failure (PHLF) which is a life-threatening complication. Liver hardness measurement (LSM) is widely used in non-invasive assessment of liver fibrosis. ...

    Authors: Jie-wen Lei, Xiao-yu Ji, Jun-feng Hong, Wan-bin Li, Yan Chen, Yan Pan and Jia Guo
    Citation: BMC Gastroenterology 2017 17:171
    Content type: Research article Published on:

  22. The burden of disease caused by Streptococcus agalactiae has increased significantly among older adults in the last decades. Group B streptococcus infection can be associated with invasive disease and severe clin...

    Authors: Pietro Achilli, Angelo Guttadauro, Paolo Bonfanti, Sabina Terragni, Luca Fumagalli, Ugo Cioffi, Francesco Gabrielli, Matilde De Simone and Marco Chiarelli
    Citation: BMC Gastroenterology 2017 17:170
    Content type: Case report Published on:

  23. Chemokines/cytokines play important roles in the pathogenesis of chronic hepatitis C (CHC). However, their clinical characteristics and implications in treatment responses to pegylated interferon plus ribaviri...

    Authors: Chia-Chen Lin, Shih-Huan Su, Wen-Juei Jeng, Chien-Hao Huang, Wei Teng, Wei-Ting Chen, Yi-Cheng Chen, Chun-Yen Lin and I-Shyan Sheen
    Citation: BMC Gastroenterology 2017 17:169
    Content type: Research article Published on:

  24. Hepatitis B virus (HBV) chronic infection affects up to 240 million people in the world and it is a common cause of cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) pla...

    Authors: Sonia Alonso, Adriana-René Guerra, Lourdes Carreira, Juan-Ángel Ferrer, María-Luisa Gutiérrez and Conrado M. Fernandez-Rodriguez
    Citation: BMC Gastroenterology 2017 17:168
    Content type: Review Published on:

  25. Extramedullary plasmacytoma is a very rare tumor derived from plasma cells and found outside the bone marrow. Most have been identified in patients with the more aggressive anaplastic form of the disease. Only...

    Authors: Tao Lu, Hong Pu and Gaoping Zhao
    Citation: BMC Gastroenterology 2017 17:167
    Content type: Case report Published on:

  27. Upper gastrointestinal bleeding (UGIB) is a common gastrointestinal emergency, which is potentially fatal. Proper management of UGIB requires risk-stratification of patients which can guide the type and aggres...

    Authors: Sibtain M. Moledina and Ewaldo Komba
    Citation: BMC Gastroenterology 2017 17:165
    Content type: Research article Published on:

  28. The number of bariatric interventions for morbid obesity is increasing worldwide. Rapid weight loss is a major risk factor for gallstone development. Approximately 11 % of patients who underwent Roux-en-Y gast...

    Authors: Thomas C. C. Boerlage, Sylke Haal, L. Maurits de Brauw, Yair I. Z. Acherman, Sjoerd Bruin, Arnold W. J. M. van de Laar, Daan E. Moes, Bart A. van Wagensveld, Claire E. E. de Vries, Ruben van Veen, Ruben Schouten, Marcel G. Dijkgraaf, Paul Fockens, Victor E. A. Gerdes and Rogier P. Voermans
    Citation: BMC Gastroenterology 2017 17:164
    Content type: Study protocol Published on:

    The Update to this article has been published in Trials 2020 21:676

  29. Increasing attention is focused on the relationship of inflammation biomarkers with malignant tumors. The purpose of the present study was to detect whether the preoperative the red distribution width (RDW) an...

    Authors: Shiqing Cheng, Fuyan Han, Yong Wang, Yanqiu Xu, Teng Qu, Ying Ju and Zhiming Lu
    Citation: BMC Gastroenterology 2017 17:163
    Content type: Research article Published on:

  30. In recent years, there has been growing concern about the overuse of colonoscopy (CC). Our objective was to evaluate the incidence rate and cumulative probability of having a potentially inadequate CC (PI-CC, ...

    Authors: Santiago Esteban, Ricardo Ricci, Sergio Terrasa and Karin Kopitowski
    Citation: BMC Gastroenterology 2017 17:162
    Content type: Research article Published on:

  31. To assess the feasibility of noninvasive and quantitative evaluation of hepatic pathophysiological changes in rabbit hepatic warm ischemia-reperfusion injury (WIRI) models by using intravoxel incoherent motion...

    Authors: Qian Ji, Zhi Qiang Chu, Tao Ren, Shi Chao Xu, Long Jiang Zhang, Wen Shen and Guang Ming Lu
    Citation: BMC Gastroenterology 2017 17:161
    Content type: Research article Published on:

  32. Children and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limit...

    Authors: Laura Mählmann, Markus Gerber, Raoul I. Furlano, Corinne Legeret, Nadeem Kalak, Edith Holsboer-Trachsler and Serge Brand
    Citation: BMC Gastroenterology 2017 17:160
    Content type: Research article Published on:

  33. Risk scoring systems are used to evaluate patients with upper gastrointestinal bleeding (UGIB). We compared Glasgow-Blatchford score (GBS), modified GBS (mGBS), and Pre-endoscopy Rockall score (Pre-E RS) for i...

    Authors: Il-Gyu Ko, Sung-Eun Kim, Bok Soon Chang, Min Seob Kwak, Jin Young Yoon, Jae Myung Cha, Hyun Phil Shin, Joung Il Lee, Sang Hyun Kim, Jin Hee Han and Jung Won Jeon
    Citation: BMC Gastroenterology 2017 17:159
    Content type: Research article Published on:

  34. Serrated adenocarcinoma (SAC) is a distinct colorectal carcinoma variant that accounts for approximately 7.5% of all advanced colorectal carcinomas. While its prognosis is worse than conventional carcinoma, it...

    Authors: Daiki Hirano, Shiro Oka, Shinji Tanaka, Kyoku Sumimoto, Yuki Ninomiya, Yuzuru Tamaru, Kenjiro Shigita, Nana Hayashi, Yuji Urabe, Yasuhiko Kitadai, Fumio Shimamoto, Koji Arihiro and Kazuaki Chayama
    Citation: BMC Gastroenterology 2017 17:158
    Content type: Research article Published on:

  35. Gastric cancer (GC) has a poor prognosis with wide variation in survival rates across the world. Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (IM) influence ga...

    Authors: Andrew D. Spence, Chris R. Cardwell, Úna C. McMenamin, Blanaid M. Hicks, Brian T. Johnston, Liam J. Murray and Helen G. Coleman
    Citation: BMC Gastroenterology 2017 17:157
    Content type: Research article Published on:

  36. The only treatment for celiac disease (CeD) is a lifelong gluten-free diet (GFD). The restrictive nature of the GFD makes adherence a challenge. As an integral part of CeD management, multiple professional org...

    Authors: Jacob J. Hughey, Bonnie K. Ray, Anne R. Lee, Kristin N. Voorhees, Ciaran P. Kelly and Detlef Schuppan
    Citation: BMC Gastroenterology 2017 17:156
    Content type: Research article Published on:

  37. Infected pancreatic necrosis (IPN) is a serious local complication of acute pancreatitis, with high mortality. Minimally invasive therapy including percutaneous catheter drainage (PCD) has become the preferred...

    Authors: Pi Liu, Jun Song, Hua-jing Ke, Nong-hua Lv, Yin Zhu, Hao Zeng, Yong Zhu, Liang Xia, Wen-hua He, Ji Li, Xin Huang and Yu-peng Lei
    Citation: BMC Gastroenterology 2017 17:155
    Content type: Technical advance Published on:

  38. The serum gradient of hepatitis B surface antigen (HBsAg) varies over time after cessation of nucleos(t)ide analog (NA) treatment in patients with chronic hepatitis B (CHB). The association between the time-va...

    Authors: Nai-Hsuan Chien, Yen-Tsung Huang, Chun-Ying Wu, Chi-Yang Chang, Ming-Shiang Wu, Jia-Horng Kao, Lein-Ray Mo, Chi-Ming Tai, Chih-Wen Lin, Tzeng-Huey Yang, Jaw-Town Lin and Yao-Chun Hsu
    Citation: BMC Gastroenterology 2017 17:154
    Content type: Research article Published on:

  39. Gallbladder disease (GBD) is a highly prevalent condition; however, little is known about potential differences in risk factors by sex and ethnicity/race. Our aim was to evaluate dietary, reproductive and obes...

    Authors: Jane C. Figueiredo, Christopher Haiman, Jacqueline Porcel, James Buxbaum, Daniel Stram, Neal Tambe, Wendy Cozen, Lynne Wilkens, Loic Le Marchand and Veronica Wendy Setiawan
    Citation: BMC Gastroenterology 2017 17:153
    Content type: Research article Published on:

  40. Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left unt...

    Authors: Flaminia Purchiaroni, Takeshi Nakajima, Taku Sakamoto, Seiichiro Abe and Yutaka Saito
    Citation: BMC Gastroenterology 2017 17:152
    Content type: Case report Published on:

  41. Esophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy ...

    Authors: Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Homma Taku, Moritaka Ohhara, Toshirou Takimoto and Yoshiaki Tanaka
    Citation: BMC Gastroenterology 2017 17:151
    Content type: Case report Published on:

  42. Blue laser imaging (BLI) and linked color imaging (LCI) are the color enhancement features of the LASEREO endoscopic system, which provide a narrow band light observation function and expansion and reduction o...

    Authors: Yoshikazu Yoshifuku, Yoji Sanomura, Shiro Oka, Mio Kurihara, Takeshi Mizumoto, Tomohiro Miwata, Yuji Urabe, Toru Hiyama, Shinji Tanaka and Kazuaki Chayama
    Citation: BMC Gastroenterology 2017 17:150
    Content type: Research article Published on:

  43. Non-alcoholic fatty liver disease (NAFLD) has been recently identified as a risk factor of gastrointestinal tract cancers, especially hepatocellular carcinoma, and colorectal cancer. Whether NAFLD is a risk fa...

    Authors: Nicha Wongjarupong, Buravej Assavapongpaiboon, Paweena Susantitaphong, Wisit Cheungpasitporn, Sombat Treeprasertsuk, Rungsun Rerknimitr and Roongruedee Chaiteerakij
    Citation: BMC Gastroenterology 2017 17:149
    Content type: Research article Published on:

  44. Irritable bowel syndrome (IBS) is a common functional disease of the gastrointestinal tract. The current study aimed to examine the association between visceral hypersensitivity in IBS and cortical activation ...

    Authors: Danping Wang, Xie Zhang, Xuesong Zhang, Zhigang Huang and Yufei Song
    Citation: BMC Gastroenterology 2017 17:148
    Content type: Research article Published on:

  45. Gastric cancer is a frequent malignant tumor worldwide and its early detection is crucial for curing the disease and enhancing patients’ survival rate. This study aimed to assess whether the multi-disciplinary...

    Authors: Lianjun Di, Huichao Wu, Rong Zhu, Youfeng Li, Xinglong Wu, Rui Xie, Hongping Li, Haibo Wang, Hua Zhang, Hong Xiao, Hui Chen, Hong Zhen, Kui Zhao, Xuefeng Yang, Ming Xie and Bigung Tuo
    Citation: BMC Gastroenterology 2017 17:147
    Content type: Research article Published on:

  46. Pancreatic hamartomas are extremely rare and may be misdiagnosed as malignant tumors. We report herein a case of a small, solid-type pancreatic hamartoma.

    Authors: Hiroaki Nagano, Masayuki Nakajo, Yoshihiko Fukukura, Yoriko Kajiya, Atsushi Tani, Sadao Tanaka, Mari Toyota, Toru Niihara, Masaki Kitazono, Toyokuni Suenaga and Takashi Yoshiura
    Citation: BMC Gastroenterology 2017 17:146
    Content type: Case report Published on:

  47. Portal vein embolization is essential for patients with biliary cancer who undergo extended hepatectomy to induce hypertrophy of the future remnant liver. Over 830 patients have undergone the portal vein embol...

    Authors: Chun-Yi Tsai, Motoi Nojiri, Yukihiro Yokoyama, Tomoki Ebata, Takashi Mizuno and Masato Nagino
    Citation: BMC Gastroenterology 2017 17:144
    Content type: Case report Published on:

  48. Pancreatic cancer occurs more frequently in older patients, but these are underrepresented in the phase III clinical studies that established the current treatment standards. This leads to uncertainty regardin...

    Authors: Anne Katrin Berger, Georg Martin Haag, Martin Ehmann, Anne Byl, Dirk Jäger and Christoph Springfeld
    Citation: BMC Gastroenterology 2017 17:143
    Content type: Research article Published on:

  49. Alpha-fetoprotein (AFP) is a biomarker for hepatocellular carcinoma (HCC). The significance of pre-treatment AFP (pt-AFP) in non-viral HCC (nvHCC) is not clear.

    Authors: Siriwardana Rohan Chaminda, Thilakarathne Suchintha, Niriella Madunil Anuk, Dassanayake Anuradha Supun, Gunathilake Mahen Bhagya, Liyanage Chandika Anuruddha Habarakada and De Silva Hithadurage Janaka
    Citation: BMC Gastroenterology 2017 17:142
    Content type: Research article Published on:

  50. The prognosis of a gastrointestinal stromal tumor (GIST) is influenced by its anatomic site; however, few studies on the prognosis of gastric GISTs have been reported. The aims of this study were to evaluate l...

    Authors: Chul Hong Park, Gwang Ha Kim, Bong Eun Lee, Geun Am Song, Do Youn Park, Kyung Un Choi, Dae Hwan Kim and Tae Yong Jeon
    Citation: BMC Gastroenterology 2017 17:141
    Content type: Research article Published on:
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