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  1. There are obviously ethnic differences between the UGT1A1 gene polymorphisms. Due to the difference of genetic background and environment, the treatment with colorectal cancer patients of Guangxi Zhuang should no...

    Authors: Shaojun Chen, Li Hua, Chengjun Feng, Qia Mo, Mengzhuan Wei, Yongqi Shen, Zhan Lin, Guisheng Li, Junyi Xu, Chengxian Guo and Haixin Huang
    Citation: BMC Gastroenterology 2020 20:96
  2. There are conflicting data regarding the risk of hepatocellular carcinoma (HCC) after direct-acting antiviral agent (DAA) treatment. Risk of HCC in HCV genotype-3 infected persons after DAA therapy is not well...

    Authors: Ghias Un Nabi Tayyab, Shafqat Rasool, Bilal Nasir, Ghazala Rubi, Abdul-Badi Abou-Samra and Adeel A. Butt
    Citation: BMC Gastroenterology 2020 20:93
  3. Endoscopic balloon dilation and/or plastic stent placement has been a standard method for treating biliary strictures complicated post living donor liver transplantation (LDLT). The strictures may be refractor...

    Authors: Mitsuhito Koizumi, Teru Kumagi, Taira Kuroda, Yoshiki Imamura, Kozue Kanemitsu, Kohei Ogawa, Yasutsugu Takada and Yoichi Hiasa
    Citation: BMC Gastroenterology 2020 20:92
  4. Liver disease is a leading cause of morbidity and mortality among Human Immunodeficiency virus (HIV) infected patients; however no consensus exists on HIV-related risk factors for it. The aim of this study was...

    Authors: Theodoros Androutsakos, Maria Schina, Abraham Pouliakis, Athanasios Kontos, Nikolaos Sipsas and Gregorios Hatzis
    Citation: BMC Gastroenterology 2020 20:91
  5. Previous reports of foreign-body ingestion focused primarily on accidental ingestion and very few studies focused on intentional ingestion of foreign body (FB) in China. Our study aimed to compare the prevalen...

    Authors: Ye Zong, Haiying Zhao, Can Sun, Ming Ji, Yongdong Wu, Shutian Zhang and Yongjun Wang
    Citation: BMC Gastroenterology 2020 20:90
  6. The Gut and Obesity in Asia (GOASIA) Workgroup was formed to study obesity and gastrointestinal diseases in the Asia Pacific region. We aimed to 1) compare the characteristics of elderly (i.e. age ≥ 60) vs. no...

    Authors: Panyavee Pitisuttithum, Wah Kheong Chan, Panida Piyachaturawat, Kento Imajo, Atsushi Nakajima, Yosuke Seki, Kazunori Kasama, Satoru Kakizaki, Jian Gao Fan, Myeong Jun Song, Seung Kew Yoon, Yock Young Dan, Laurentius Lesmana, Khek Yu Ho, Khean Lee Goh, Vincent Wai Sun Wong…
    Citation: BMC Gastroenterology 2020 20:88
  7. Endoscopic placement of intestinal decompression tubes is a feasible technique for treatment of acute intestinal dilation. Given the heterogeneity of the underlying diseases leading to intestinal obstruction d...

    Authors: Thorsten Book, Martha M. Kirstein, Andrea Schneider, Michael P. Manns and Torsten Voigtländer
    Citation: BMC Gastroenterology 2020 20:87
  8. Rome IV criteria for functional gastrointestinal disorders state that children suspected of having Irritable Bowel Syndrome (IBS) with Constipation (IBS-C) should be preliminarily treated for constipation. We ...

    Authors: Monica Tosto, Paola D’Andrea, Ignazio Salamone, Salvatore Pellegrino, Stefano Costa, Maria Cristina Lucanto, Socrate Pallio, Giuseppe Magazzu’ and Stefano Guandalini
    Citation: BMC Gastroenterology 2020 20:86
  9. Many studies have revealed that mucosal healing improves the long-term prognosis of ulcerative colitis. Frequent colonoscopy is difficult because of its invasiveness and cost. Therefore, in diagnosing and trea...

    Authors: Masaki Wakai, Ryohei Hayashi, Shinji Tanaka, Toshikatsu Naito, Junko Kumada, Motonobu Nomura, Hidehiko Takigawa, Shiro Oka, Yoshitaka Ueno, Masanori Ito and Kazuaki Chayama
    Citation: BMC Gastroenterology 2020 20:85
  10. The incidence of cirrhosis for individuals in Sweden has previously been reported as stable/low among European countries. However, Swedish population-based studies are scarce and none of them included data fro...

    Authors: Juan Vaz, Berne Eriksson, Ulf Strömberg, David Buchebner and Patrik Midlöv
    Citation: BMC Gastroenterology 2020 20:84
  11. Gastroesophageal variceal hemorrhage is the most severe complication of portal hypertension, with a high mortality rate. The current recommendations for gastroesophageal varices include pharmacological treatme...

    Authors: Yujen Tseng, Lili Ma, Minzhi Lv, Tiancheng Luo, Chengfeng Liu, Yichao Wei, Chu Liu, Ji Zhou, Zhiping Yan, Pengju Xu, Guohua Hu, Hong Ding, Yuan Ji, Shiyao Chen and Jian Wang
    Citation: BMC Gastroenterology 2020 20:83
  12. Percutaneous Endoscopic Gastrostomy (PEG) feeding tubes are frequently placed in patients to provide enteral nutrition. We report a case of a complete rupture of a PEG tube intra-abdominally with associated pe...

    Authors: Maan Al Halabi, Wakim Wakim, Hicham Moukaddam and Ahmad Husari
    Citation: BMC Gastroenterology 2020 20:82
  13. Vascular invasion is an important criterion for resectability and deciding the therapeutic strategy for pancreatic ductal adenocarcinoma (PDAC), but imaging diagnosis is currently difficult. Endoscopic ultraso...

    Authors: Kenta Yamada, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Hiroyuki Tanaka, Masanao Nakamura, Ryoji Miyahara, Masatoshi Ishigami, Yoshiki Hirooka and Mitsuhiro Fujishiro
    Citation: BMC Gastroenterology 2020 20:81
  14. The prevalence of malnutrition remains high in hospitals but no “gold standard” has been established to identify nutritional risks adequately. The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global As...

    Authors: Mariana Chávez-Tostado, Gabino Cervantes-Guevara, Sandra Estefanía López-Alvarado, Gabino Cervantes-Pérez, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Diana Mercedes Hernández-Corona, Tonatiuh González-Heredia, Guillermo Alonso Cervantes-Cardona and Alejandro González-Ojeda
    Citation: BMC Gastroenterology 2020 20:79
  15. The database used for the NHS Bowel Cancer Screening Programme (BCSP) derives participant information from primary care records. Combining predictors with FOBTs has shown to improve referral decisions and accu...

    Authors: Jennifer Anne Cooper, Ronan Ryan, Nick Parsons, Chris Stinton, Tom Marshall and Sian Taylor-Phillips
    Citation: BMC Gastroenterology 2020 20:78
  16. There are several studies with varied and mixed results about the possible relationship between H. pylori and diabetes. Therefore, this current meta-analysis performed to determine the association between H. pylo...

    Authors: Kamyar Mansori, Yousef Moradi, Sara Naderpour, Roya Rashti, Ali Baradaran Moghaddam, Lotfolah Saed and Hedyeh Mohammadi
    Citation: BMC Gastroenterology 2020 20:77
  17. Kaposi’s sarcoma (KS) is a rare vascular tumor associated with human herpesvirus (HHV)-8 infection. One of the variants of KS is defined iatrogenic and is overall reported in transplanted patient but also, alt...

    Authors: Valerio Papa, Maria Cristina Giustiniani, Loris Riccardo Lopetuso and Alfredo Papa
    Citation: BMC Gastroenterology 2020 20:76
  18. The intestinal epithelial barrier allows absorption of dietary nutrients and prevents passage of pathogens and toxins into the body. Severe insults have a negative impact on the intestinal environment, which m...

    Authors: Masaaki Motoori, Koji Tanaka, Keijiro Sugimura, Hiroshi Miyata, Takuro Saito, Yasuhiro Miyazaki, Kazumasa Fujitani, Yukiko Kado, Takashi Asahara and Masahiko Yano
    Citation: BMC Gastroenterology 2020 20:74
  19. Short-chain fatty acids (SCFAs) alteration have been reported in irritable bowel syndrome (IBS), but the results are conflicting. Our study aims to explore the alteration of SCFAs in patients with diarrhea-pre...

    Authors: Zhenyi Tian, Xiaojun Zhuang, Mei Luo, Wei Yin and Lishou Xiong
    Citation: BMC Gastroenterology 2020 20:73
  20. Esophageal intramural pseudodiverticulosis is an uncommon, idiopathic disorder characterized by multiple small outpouchings protruding from the esophageal lumen. Esophageal intramural pseudodiverticulosis is a...

    Authors: Osman Ali, Hazel Asumu, Tanisha Kaur, Angelina Mathew and Raymond Kim
    Citation: BMC Gastroenterology 2020 20:72
  21. This study aimed to develop prognostic models for predicting 28- and 90-day mortality rates of hepatitis B virus (HBV)-associated acute-on-chronic liver failure (HBV-ACLF) through artificial neural network (AN...

    Authors: Yixin Hou, Qianqian Zhang, Fangyuan Gao, Dewen Mao, Jun Li, Zuojiong Gong, Xinla Luo, Guoliang Chen, Yong Li, Zhiyun Yang, Kewei Sun and Xianbo Wang
    Citation: BMC Gastroenterology 2020 20:75
  22. Loeys-Dietz syndrome (LDS) is a systemic connective tissue disease (CTD) associated with a predisposition for intestinal inflammation, food allergy, and failure to thrive, often necessitating nutritional suppl...

    Authors: Pamela A. Frischmeyer-Guerrerio, Gretchen MacCarrick, Harry C. Dietz, F. Dylan Stewart and Anthony L. Guerrerio
    Citation: BMC Gastroenterology 2020 20:71
  23. Endoscopic full-thickness resection (EFTR) is difficult to perform in a retroflexed fashion in the gastric fundus. The present study aims at exploring whether direct EFTR can be a simple, effective and safe pr...

    Authors: Jinlong Hu, Nan Ge, Sheng Wang, Jintao Guo, Xiang Liu, Guoxin Wang and Siyu Sun
    Citation: BMC Gastroenterology 2020 20:70
  24. Meckel’s diverticulum is a remnant of the omphalomesenteric duct. It can lead to intestinal perforation, obstruction and gastrointestinal bleeding. While the internal hernia caused by Meckel’s diverticulum is ...

    Authors: Yang Zhang, Yuchen Guo, Yuanlin Sun and Yuechao Xu
    Citation: BMC Gastroenterology 2020 20:69
  25. Although prophylactic clip application before polypectomy may prevent postpolypectomy bleeding (PPB), the usefulness of prophylactic clipping in the treatment of large pedunculated polyps is controversial in s...

    Authors: Jae Seung Soh, Myeongsook Seo and Kyung-Jo Kim
    Citation: BMC Gastroenterology 2020 20:68
  26. Advances in surgical techniques and perioperative care have improved the short- and mid-term postoperative outcomes of patients with Hirschsprung disease (HD). However, the long-term outcomes of these patients...

    Authors: Ying Dai, Yongfang Deng, Yan Lin, Runxian Ouyang and Le Li
    Citation: BMC Gastroenterology 2020 20:67
  27. Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease nowadays. Changes in diet and lifestyle have led to a dramatic increase in the prevalence of NAFLD around t...

    Authors: Shu-ting Wang, Jing Zheng, He-wei Peng, Xiao-lin Cai, Xin-ting Pan, Hui-quan Li, Qi-zhu Hong and Xian-E Peng
    Citation: BMC Gastroenterology 2020 20:66
  28. Ineffective antibiotic therapy increases mortality of acute cholangitis. The choice of antibiotics should reflect local resistance patterns and avoid the overuse of broad-spectrum agents. In this study, we ana...

    Authors: Tassilo Kruis, Sarah Güse-Jaschuck, Britta Siegmund, Thomas Adam and Hans-Jörg Epple
    Citation: BMC Gastroenterology 2020 20:65
  29. Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly performed in the management of pancreatic and biliary disease. Duodenoscopes are specialized endoscopes used to perform ERCP, and inherent to ...

    Authors: Nauzer Forbes, B. Joseph Elmunzer, Thibault Allain, Millie Chau, Hannah F. Koury, Sydney Bass, Paul J. Belletrutti, Martin J. Cole, Emmanuel Gonzalez-Moreno, Ahmed Kayal, Puja Kumar, Rachid Mohamed, Christian Turbide, Andre G. Buret and Steven J. Heitman
    Citation: BMC Gastroenterology 2020 20:64
  30. Pseudoachalasia is a rare disorder which has clinical, radiographic, and manometric findings that are often indistinguishable from primary achalasia. It is usually associated with malignancy. Few reports descr...

    Authors: Marian Dejaeger, Maud Lormans, Eddy Dejaeger and Katleen Fagard
    Citation: BMC Gastroenterology 2020 20:63
  31. Crigler Najjar type 1 is a rare autosomal recessive condition caused by the absence of UDPGT enzyme due to mutations in the UGT1A1 gene. This enzyme is responsible for elimination of unconjugated bilirubin fro...

    Authors: Sailaja Valmiki, Kiran Kumar Mandapati, Leela Krishna Vamsee Miriyala, Chayarani Chandrashekhar Kelgeri, Mohamed Rela, Naresh P. Shanmugam and Durga Rao Vegulada
    Citation: BMC Gastroenterology 2020 20:62
  32. Mucormycosis is rare, life-threatening fungal infection. Frequently observed in those patients having underlying immunosuppression such as, diabetes, organ transplantation, Human immunodeficiency virus (HIV) i...

    Authors: Abdi Bati Wotiye, Poornachandra KS and Biniyam Alemayehu Ayele
    Citation: BMC Gastroenterology 2020 20:61
  33. Endoscopic mucosal resection (EMR) is a minimally invasive procedure used for the treatment of lesions in the gastrointestinal (GI) tract. There is increased usage of hemoclips during EMR for the prevention of...

    Authors: Karen Chang, Brian S. Lee, Timnit Tekeste, Andrew Nguyen, Mopelola Adeyemo, Agathon Girgis, Karl K. Kwok, H. Michael Crowson, Alicia O. Burris, Rajeev Attam, Charles T. Chaya, Theodore E. Durbin, Andrew Q. Giap, Gordon C. Hunt, John Iskander, Kevin T. Kao…
    Citation: BMC Gastroenterology 2020 20:60
  34. The gut microbiota participates in the metabolism of substances and energy, promotes the development and maturation of the immune system, forms the mucosal barrier, and protects the host from pathogen attacks....

    Authors: Qiang Wang, Chenjun Hao, Wenchao Yao, Defu Zhu, Haifeng Lu, Long Li, Biao Ma, Bei Sun, Dongbo Xue and Weihui Zhang
    Citation: BMC Gastroenterology 2020 20:59
  35. Prognostic value or clinical implications of fluid status monitoring in liver cirrhosis are not fully elucidated. Tolvaptan, an orally available, selective vasopressin V2-receptor antagonist approved for hypon...

    Authors: Shunsuke Shiba, Po-sung Chu, Nobuhiro Nakamoto, Karin Yamataka, Nobuhito Taniki, Keisuke Ojiro, Akihiro Yamaguchi, Rei Morikawa, Aya Yoshida, Akihiko Ikura, Hirotoshi Ebinuma, Hidetsugu Saito and Takanori Kanai
    Citation: BMC Gastroenterology 2020 20:53
  36. The implication of microscopic ileitis finding in patients referred for ileocolonoscopy for clinically suspected inflammatory bowel disease (IBD) is not well defined, and its correlation with clinical outcome ...

    Authors: Fadi Abu Baker, Jesus Alonso Z’cruz De La Garza, Smadar Nafrin, Amir Mari, Muhammed Suki, Baruch Ovadia, Oren Gal and Yael Kopelamn
    Citation: BMC Gastroenterology 2020 20:52
  37. Lymph node (LN) metastasis is negligible in early gastric cancer (EGC) within expanded criteria for endoscopic submucosal dissection (ESD). However, regional lymph nodes in abdominal CT scans are sometimes enl...

    Authors: Dong Seok Lee, Jong Kyu Park, Sang Jin Lee and Gab Jin Cheon
    Citation: BMC Gastroenterology 2020 20:51
  38. We investigated real-world effectiveness and safety of sofosbuvir and the nonstructural protein 5A inhibitors in the treatment of patients infected with hepatitis C virus (HCV) genotypes 1, 2, 3, 4, or 6.

    Authors: Phunchai Charatcharoenwitthaya, Virasak Wongpaitoon, Piyawat Komolmit, Wattana Sukeepaisarnjaroen, Pisit Tangkijvanich, Teerha Piratvisuth, Theeranun Sanpajit, Chinnavat Sutthivana, Chalermrat Bunchorntavakul, Abhasnee Sobhonslidsuk, Soonthorn Chonprasertsuk, Chotipong Siripipattanamongkol, Supatsri Sethasine and Tawesak Tanwandee
    Citation: BMC Gastroenterology 2020 20:47
  39. Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in combination with hepatic inflammation and fibro...

    Authors: Atsuko Takai, Kentaro Kikuchi, Mayuko Ichimura, Koichi Tsuneyama, Yuki Moritoki, Kotaro Matsumoto, Hiromichi Tsunashima, Takeshi Onda, Noriyuki Kuniyoshi, Tomoyuki Nariyama, Sho Ohyatsu, Juri Kubota, Kozue Nagumo, Shinpei Sato, Masumi Hara and Hiroshi Miyakawa
    Citation: BMC Gastroenterology 2020 20:46
  40. Gastroesophageal reflux disease (GORD) is a chronic and a common condition worldwide which causes mild to severe symptoms. Private tuition attendees are a group which could have potential risk factors for GORD...

    Authors: Darsha Gunasinghe, Chathurika Gunawardhana, Shakthi Halahakoon, Ali Haneeka, Najiyya Hanim, Chamara Hapuarachchi and Devarajan Rathish
    Citation: BMC Gastroenterology 2020 20:45
  41. Owing to the development of double-balloon enteroscopy (DBE) and video capsule endoscopy (VCE) in recent years, direct visualization of the entire small intestinal mucosa has become possible. Because of the no...

    Authors: Zihan Huang, Xiang Liu, Fei Yang, Guoxin Wang, Nan Ge, Sheng Wang, Jintao Guo and Siyu Sun
    Citation: BMC Gastroenterology 2020 20:42
  42. The level and profiles of blood free carnitine and acylcarnitines, obtained by acylcarnitine analysis using tandem mass spectrometry, reflect various metabolic conditions. We aimed to examine the level of free...

    Authors: Hisamitsu Miyaaki, Hironori Kobayashi, Satoshi Miuma, Masanori Fukusima, Ryu Sasaki, Masafumi Haraguchi and Kazuhiko Nakao
    Citation: BMC Gastroenterology 2020 20:41
  43. Hyperuricemia is a major risk for non-alcoholic fatty liver disease. However, the mechanisms for this phenomenon are not fully understood. This study aimed to investigate whether microRNAs mediated the pathoge...

    Authors: Shenghui Chen, Dan Chen, Hua Yang, Xinyu Wang, Jinghua Wang and Chengfu Xu
    Citation: BMC Gastroenterology 2020 20:39
  44. Following publication of the original article [1], we have been notified that the given name of one of the authors was spelled incorrectly.

    Authors: Pengzi Zhang, Wenhuan Feng, Xuehui Chu, Xitai Sun, Dalong Zhu and Yan Bi
    Citation: BMC Gastroenterology 2020 20:38

    The original article was published in BMC Gastroenterology 2019 19:202

  45. Gastric schwannomas are rare benign tumors originating from the intramuscular plexus of the stomach and account for just 2.6% of gastric mesenchymal tumors. Gastric schwannoma (GS) with a surface ulcer is very...

    Authors: Caihua Tang, Qiyong Pan, Zeqing Xu, Xuan Zhou and Ying Wang
    Citation: BMC Gastroenterology 2020 20:36

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