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  1. Esophageal fistula and stricture is rare but life-threatening complication for esophageal cancer. The management of esophageal fistula and stricture remains challenging. We aimed to determine the safety, feasi...

    Authors: Yonghua Bi, Mengfei Yi, Zepeng Yu, Xinwei Han and Jianzhuang Ren
    Citation: BMC Gastroenterology 2020 20:248
  2. A gluten-free diet (GFD) is the only effective treatment for celiac patients and assessing adherence to this diet is important. Celiac disease Adherence Test (CDAT) is a valid English-language questionnaire th...

    Authors: Zeinab Nikniaz, Mohammad Asghari Jafarabadi, Saeideh Ghaffarifar, Zahra Saeedi, Zahra Akbari Namvar and Masood Shirmohammadi
    Citation: BMC Gastroenterology 2020 20:247
  3. Gastric cancer develops even in Helicobacter pylori(H. pylori)-uninfected patients and its typical histological feature is signet ring cell carcinoma (SRCC) within the mucosal layer. However, the biological chara...

    Authors: Mariko Kiso, Yuji Urabe, Masanori Ito, Kazuhiko Masuda, Tomoyuki Boda, Takahiro Kotachi, Kosaku Hata, Naoki Yorita, Naoko Nagasaki, Madina Abduwali, Yuich Hiyama, Shiro Oka, Shinji Tanaka and Kazuaki Chayama
    Citation: BMC Gastroenterology 2020 20:243
  4. Cystinosis is a multisystemic disease resulting from cystine accumulation primarily in kidney and many other tissues. We intended to study the evolution of less commonly seen extrarenal complications of cystin...

    Authors: Rezan Topaloglu, Ayşe Gültekingil, Bora Gülhan, Fatih Ozaltin, Hülya Demir, Türkmen Çiftci, Numan Demir, Çağrı Mesut Temucin, Aysel Yuce and Okhan Akhan
    Citation: BMC Gastroenterology 2020 20:242

    The Correction to this article has been published in BMC Gastroenterology 2022 22:166

  5. Tumor pyruvate kinase M2 isoform (tM2-PK), which is an isoform of PK-glycolytic enzyme and appears on the surface of cancerous proliferating cells, has been used as a diagnostic biomarker for colorectal cancer...

    Authors: Farideh Rigi, Aliakbar Jannatabad, Azra Izanloo, Reza Roshanravan, Hamid Reza Hashemian and Mohammad Amin Kerachian
    Citation: BMC Gastroenterology 2020 20:241
  6. Leukocytoclastic vasculitis (LCV) is an immune-complex mediated vasculitis characterized by neutrophilic inflammation and nuclear debris in post capillary venules. LCV is a rare dermatologic manifestation of C...

    Authors: Meredith Buck, Igor Dumic, Wendy McDermott, Charles Nordstrom, Samarth Dawan, Andrew Virata, Scott Martin, Ann Hudson, Tamara Milovanovic and Terri Nordin
    Citation: BMC Gastroenterology 2020 20:240
  7. Pigmented bile salts darken the small-bowel lumen and are present with bile acid, which is involved in the development of bowel habits. The small-bowel water content (SBWC) in the ileum could represent the col...

    Authors: Taiki Aoyama, Akira Fukumoto, Kenjiro Shigita, Naoki Asayama, Shinichi Mukai and Shinji Nagata
    Citation: BMC Gastroenterology 2020 20:237
  8. The induction of chronic inflammation, perforation, and abscess by foreign bodies (FBs) in adults is uncommon. We present a delayed diagnosis case for a patient who had a fishbone stuck in the duodenal bulb, r...

    Authors: Zhihui Wang, Zhiqiang Du, Xiangrong Zhou, Tianming Chen and Chunyan Li
    Citation: BMC Gastroenterology 2020 20:236
  9. NETest, a novel multi-gene liquid biopsy has utility in neuroendocrine tumor (NET) diagnosis and identification of residual disease. We independently assessed utility of the NETest to diagnose gastric neuroend...

    Authors: A. Malczewska, A. Procner, A. Walter, K. Kusnierz, W. Zajecki, H. Aslanian and B. Kos-Kudla
    Citation: BMC Gastroenterology 2020 20:235
  10. Melatonin has been shown with anticancer property and therapeutic potential for tumors. However, there lacks a systematic study on the molecular pathways of melatonin and its antitumor effects in gastrointesti...

    Authors: Lu Ao, Li Li, Huaqin Sun, Huxing Chen, Yawei Li, Haiyan Huang, Xianlong Wang, Zheng Guo and Ruixiang Zhou
    Citation: BMC Gastroenterology 2020 20:233
  11. Gastric cancer after Helicobacter pylori (HP) eradication is a crucial clinical challenge today as HP eradication therapy is widely performed. Detecting gastric cancer after HP eradication tends to be difficult w...

    Authors: Akiko Ohno, Jun Miyoshi, Atsushi Kato, Naohiko Miyamoto, Takahito Yatagai, Yu Hada, Mitsunori Kusuhara, Yoko Jimbo, Yosuke Ida, Kengo Tokunaga, Susumu Okamoto and Tadakazu Hisamatsu
    Citation: BMC Gastroenterology 2020 20:232
  12. A recent study by Digby et al. in BMC Gastroenterology evaluated the faecal haemoglobin, age and sex test (FAST) score in the assessment of patients with lower bowel symptoms attended in primary healthcare. Th...

    Authors: Joaquín Cubiella
    Citation: BMC Gastroenterology 2020 20:231

    The original article was published in BMC Gastroenterology 2019 19:213

  13. Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload leads to increased levels of toxic non-transferrin b...

    Authors: Jessica Seeßle, Hongying Gan-Schreier, Marietta Kirchner, Wolfgang Stremmel, Walee Chamulitrat and Uta Merle
    Citation: BMC Gastroenterology 2020 20:230
  14. The aim of the study was to compare the onset of oral feeding in the first 24 h after hospital admission with usual oral refeeding and determine whether the timing of the onset of oral feeding influences the r...

    Authors: Edgard Efrén Lozada-Hernández, Omar Barrón-González, Santa Vázquez-Romero, Martin Cano-Rosas and Evelia Apolinar-Jimenez
    Citation: BMC Gastroenterology 2020 20:228
  15. Inpatient status has been shown to be a predictor of poor bowel preparation for colonoscopy; however, the optimal bowel preparation regimen for hospitalized patients is unknown. Our aim was to compare the effi...

    Authors: Patricia V. Hernandez, Jennifer L. Horsley-Silva, Diana L. Snyder, Noemi Baffy, Mary Atia, Laura Koepke, Matthew R. Buras, Elisabeth S. Lim, Kevin Ruff, Sarah B. Umar, Sameer Islam and Francisco C. Ramirez
    Citation: BMC Gastroenterology 2020 20:227
  16. Patients co-infected with hepatitis B virus (HBV) and the human immunodeficiency virus (HIV) are at risk of developing hepatocellular carcinoma (HCC). In sub-Saharan Africa, the overlap between high HIV and HB...

    Authors: Tongai Gibson Maponga, Richard H. Glashoff, Hannali Vermeulen, Barbara Robertson, Sean Burmeister, Marc Bernon, Jones Omoshoro-Jones, Paul Ruff, Alfred I. Neugut, Judith S. Jacobson, Wolfgang Preiser and Monique I. Andersson
    Citation: BMC Gastroenterology 2020 20:226
  17. In the recent years two innovative approaches have become available for minimally invasive en bloc resections of large non-pedunculated rectal lesions (polyps and early cancers). One is Transanal Minimally Invasi...

    Authors: Nik Dekkers, Jurjen J. Boonstra, Leon M. G. Moons, Roel Hompes, Barbara A. Bastiaansen, Jurriaan B. Tuynman, Arjun D. Koch, Bas L. A. M. Weusten, Apollo Pronk, Peter A. Neijenhuis, Marinke Westerterp, Wilbert B. van den Hout, Alexandra M. J. Langers, Jolein van der Kraan, Alaa Alkhalaf, Jonathan Y. L. Lai…
    Citation: BMC Gastroenterology 2020 20:225
  18. Studies of microbiota composition of infants with small intestinal ostomy due to various etiologies are limited. Here, we characterized the intestinal microbiota of neonates with ileostomy resulting from disti...

    Authors: Tian Qian, Haitao Zhu, Li Zhu, Chao Chen, Chun Shen and Rong Zhang
    Citation: BMC Gastroenterology 2020 20:224
  19. Intestinal and diffuse gastric adenocarcinomas differ in clinical, epidemiological and molecular features. However, most of the concepts related to the intestinal-type are translated to gastric adenocarcinoma ...

    Authors: Paulo Pimentel Assumpção, Williams Fernandes Barra, Geraldo Ishak, Luiz Gonzaga Vaz Coelho, Felipe José Fernandez Coimbra, Helano Carioca Freitas, Emmanuel Dias-Neto, M. Constanza Camargo and Moyses Szklo
    Citation: BMC Gastroenterology 2020 20:223
  20. Recent studies have shown that bile acids (BAs) are closely related to metabolic and inflammatory diseases. Our study aimed to investigate whether circulating total bile acid (TBA) levels were associated with ...

    Authors: Xiaochun Xie, Jie Dong, Guotao Lu, Kun Gao, Xiaoyao Li, Wenjian Mao, Faxi Chen, Zhihui Tong, Baiqiang Li and Weiqin Li
    Citation: BMC Gastroenterology 2020 20:222
  21. Previous studies of the relationship between dietary factors and risk of diverticulosis have yielded inconsistent results. We therefore sought to investigate the association between consumption of fruit and ve...

    Authors: Benjamin Maxner, Jessica McGoldrick, Danielle Bellavance, Po-Hong Liu, Ramnik J. Xavier, Joseph C. Yarze, Rocco Ricciardi, Kyle Staller, Daniel C. Chung and Hamed Khalili
    Citation: BMC Gastroenterology 2020 20:221
  22. Therapy targeting programmed death-1 or programmed death-1 ligand-1 (PD-1/PD-L1) has been developed for various solid malignant tumors, such as melanoma and non-small-cell lung cancer (NSCLC), but this approac...

    Authors: Miku Obayashi, Yasushi Shibasaki, Toru Koakutsu, Yoshiro Hayashi, Tsuyoshi Shoji, Kazuhisa Hirayama, Masanori Yamazaki, Yasuhiro Takayanagi, Hiroshi Shibata, Masato Nakamura and Hirotoshi Maruo
    Citation: BMC Gastroenterology 2020 20:220
  23. There is no current standard rescue treatment for dual drug-resistant strains of Helicobacter pylori (H. pylori). This aim of this study was to investigate the efficacy of rifabutin-based triple therapy for patie...

    Authors: Chia-Jung Kuo, Cheng-Yu Lin, Puo-Hsien Le, Pi-Yueh Chang, Chih-Ho Lai, Wey-Ran Lin, Ming-Ling Chang, Jun-Te Hsu, Hao-Tsai Cheng, Chi-Nan Tseng, Chun-Jung Lin, Ming-Yao Su, Sen-Yung Hsieh and Cheng-Tang Chiu
    Citation: BMC Gastroenterology 2020 20:218
  24. Nonalcoholic fatty liver disease is characterized by excessive hepatic fat accumulation. Some individuals frequently present elevated gamma-glutamyl transferase (GGT) levels without fatty liver ultrasound imag...

    Authors: Hideki Fujii, Haruna Doi, Tetsuhisa Ko, Taito Fukuma, Toru Kadono, Kohei Asaeda, Reo Kobayashi, Takahiro Nakano, Toshifumi Doi, Yoshikazu Nakatsugawa, Shinya Yamada, Takeshi Nishimura, Naoya Tomatsuri, Hideki Sato, Yusuke Okuyama, Hiroyuki Kimura…
    Citation: BMC Gastroenterology 2020 20:217
  25. Gastroparesis is a recognized complication of diabetes but its pathogenic mechanism incompletely understood. Our aim was to determine whether HIF-1α and VEGF are secreted from gastric tissue is a fundamental f...

    Authors: Xueping Wu, Zhifang Yang, Zhihong Li, Ling Yang, Xinyan Wang, Congrong Wang and Jun Gu
    Citation: BMC Gastroenterology 2020 20:216
  26. Hepatocellular carcinoma (HCC), the most common type of liver cancer, is one of the leading causes of cancer-related death worldwide with an inferior prognosis. In Indonesia, the average life expectancy is les...

    Authors: Chyntia Olivia Maurine Jasirwan, Alessa Fahira, Lianda Siregar and Imelda Loho
    Citation: BMC Gastroenterology 2020 20:215
  27. Periampullary adenocarcinoma is a major clinical problem in high-risk patients including FAP population. A recent modification for visualizing the ampulla of Vater (AV) involves attaching a cap to the tip of t...

    Authors: Leonardo Correa Silva, Rondinelle Martins Arruda, Paula Fortuci Resende Botelho, Leonardo Nogueira Taveira, Kelly Menezio Giardina, Marco Antonio de Oliveira, Julia Dias, Cleyton Zanardo Oliveira, Gilberto Fava and Denise Peixoto Guimarães
    Citation: BMC Gastroenterology 2020 20:214
  28. Although endoscopic resection is safe and effective for gastric epithelial neoplasms, information is limited on its efficacy and safety in extremely elderly patients who have various comorbidities. Further, th...

    Authors: Sunmin Kim, Dong Hyun Kim, Seon-Young Park, Chang Hwan Park, Hyun Soo Kim, Sung Kyu Choi and Jong Sun Rew
    Citation: BMC Gastroenterology 2020 20:213
  29. To evaluate an innovative open necrosectomy strategy with continuous positive drainage and prophylactic diverting loop ileostomy for the management of late infected pancreatic necrosis (LIPN).

    Authors: Dong-Guang Niu, Wei-Qin Li, Qian Huang, Fan Yang, Wei-Liang Tian, Chen Li, Lian-An Ding, Hong-Chun Fang and Yun-Zhao Zhao
    Citation: BMC Gastroenterology 2020 20:212
  30. Real-world comparisons of biologic treatment outcomes for ulcerative colitis (UC) or Crohn’s disease (CD) patients are limited. We sought to evaluate the real-world effectiveness of vedolizumab (VDZ) and anti-...

    Authors: Ulf Helwig, Michael Mross, Stefan Schubert, Heinz Hartmann, Alina Brandes, Dara Stein, Christian Kempf, Jana Knop, Sarah Campbell-Hill and Robert Ehehalt
    Citation: BMC Gastroenterology 2020 20:211
  31. Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. ...

    Authors: Henrik H. Hansen, Helene M. Ægidius, Denise Oró, Simon S. Evers, Sara Heebøll, Peter Lykke Eriksen, Karen Louise Thomsen, Anja Bengtsson, Sanne S. Veidal, Michel Feigh, Malte P. Suppli, Filip K. Knop, Henning Grønbæk, Diego Miranda, James L. Trevaskis, Niels Vrang…
    Citation: BMC Gastroenterology 2020 20:210
  32. Functional dyspepsia (FD), belching disorders (BD) and functional heartburn (FH) are the three most common upper functional gastrointestinal disorders (FGID) in IBS patients. FD is known to exert deleterious e...

    Authors: Xin Yao, Yunsheng Yang, Shutian Zhang, Yu Shi, Qian Zhang and Yongjun Wang
    Citation: BMC Gastroenterology 2020 20:209
  33. Primary hyperoxaluria (PH) is an inherited disease lacking of hepatic oxalic acid metabolic enzymes which could lead to irreverisible renal damage. Currently, liver–kidney transplantation is a curative but hig...

    Authors: Jie Xiang, Zheng Chen, Fangshen Xu, Shengmin Mei, Zhiwei Li, Jie Zhou, Yinlei Dong, Yangjun Gu, Zhichao Huang and Zhenhua Hu
    Citation: BMC Gastroenterology 2020 20:208
  34. Recurrence risk is a major concern after endoscopic resection (ER) of gastric neoplasms. This study was to compare metachronous risk in patients with and without synchronous neoplasms after complete ER.

    Authors: Ga-Yeong Shin, Hye Jin Cho, Jae Myung Park, Chul-Hyun Lim, Yu Kyung Cho and Myung-Gyu Choi
    Citation: BMC Gastroenterology 2020 20:206
  35. Transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and iodine 125 seeds implantation are optional treatments for hepatocellular carcinoma (HCC). The aim of this study is to compare the effi...

    Authors: Lei Chen, Xuefeng Kan, Tao Sun, Yanqiao Ren, Yanyan Cao, Liangliang Yan, Bin Liang, Bin Xiong and Chuansheng Zheng
    Citation: BMC Gastroenterology 2020 20:205
  36. Adult lactase non-persistence (LNP) is due to low lactase expression, resulting in lactose malabsorption (LM). LNP is a genetic trait, but is typically determined by LM markers including breath H2, blood glucose,...

    Authors: Aahana Shrestha, Matthew P. G. Barnett, Jo K. Perry, David Cameron-Smith and Amber M. Milan
    Citation: BMC Gastroenterology 2020 20:204
  37. Tacrolimus (TAC) is a powerful remission-inducing drug for refractory ulcerative colitis (UC). However, it is unclear whether mucosal healing (MH) influences relapse after completion of TAC.We investigated whe...

    Authors: Ayumi Ito, Syun Murasugi, Teppei Omori, Shinichi Nakamura and Katsutoshi Tokushige
    Citation: BMC Gastroenterology 2020 20:203
  38. Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is an extremely uncommon pancreatic neoplasm that comprises less than 1% of all exocrine pancreatic tumors. To date, cases and data from who...

    Authors: Guangjian Yang, Jiangxia Yin, Kai Ou, Qiang Du, Wenhao Ren, Yujing Jin, Liming Peng and Lin Yang
    Citation: BMC Gastroenterology 2020 20:202
  39. Surgical site infection (SSI) is one of the most common complications after pancreaticoduodenectomy (PD). Thus, it is beneficial to preoperatively identify patients at high risk of developing SSI. The primary ...

    Authors: Wikran Suragul, Narongsak Rungsakulkij, Watoo Vassanasiri, Pongsatorn Tangtawee, Paramin Muangkaew, Somkit Mingphruedhi and Suraida Aeesoa
    Citation: BMC Gastroenterology 2020 20:201
  40. To compare the outcomes of modified endoscopic mucosal resection (m-EMR) and endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (NETs) and evaluate the value of endoscopic morphology class...

    Authors: Xiang-Yao Wang, Ning-Li Chai, En-Qiang Linghu, Shao-Tian Qiu, Long-Song Li, Jia-Le Zou, Jing-Yuan Xiang and Xing-Xing Li
    Citation: BMC Gastroenterology 2020 20:200
  41. Bariatric surgery is an effective treatment for severe obesity. It also ameliorates diabetes independently of weight loss through mechanisms that are not fully understood. In this study, we investigated the le...

    Authors: Khalid Al-Regaiey, Suad Alshubrami, Ibrahim Al-Beeshi, Torki Alnasser, Abdulnasser Alwabel, Hassan Al-Beladi, Omar Al-Tujjar, Abdulrahman Alnasser, Assim A. Alfadda and Muhammad Iqbal
    Citation: BMC Gastroenterology 2020 20:199
  42. To investigate the effect of albumin infusion on cirrhotic patients admitted for acute gastrointestinal bleeding.

    Authors: Zhu Wang, Ya-Wen Xie, Qing Lu, Hai-Lin Yan, Xin-Bin Liu, Yi Long, Xian Zhang and Jin-Lin Yang
    Citation: BMC Gastroenterology 2020 20:198
  43. Whipple’s disease is a rare systemic disease caused by a gram-positive bacillus called Tropheryma whipplei. First described in 1907 as an intestinal lipodystrophy with histological finding of vacuoles in the m...

    Authors: Margarita Rey R., Luis Alejandro Orozco, Katherine Marrugo, Rocio López, Erika D. Pérez-Riveros, José De la Hoz-Valle and Fernando Sierra-Arango
    Citation: BMC Gastroenterology 2020 20:197
  44. Placement of nasogastric (NG) tubes is a common procedure for patients especially in intensive care units (ICUs). Thus, it is important to determine the correct placement of the tube to prevent misplacement in...

    Authors: Elahe Heidarzadi, Rostam Jalali, Behzad Hemmatpoor and Nader Salari
    Citation: BMC Gastroenterology 2020 20:196

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