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Nutrition and metabolism

This section concerns the involvement of the gastrointestinal tract in regulating metabolism as well as the involvement of nutrition in gastroenterological disorders.

  1. Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload leads to increased levels of toxic non-transferrin b...

    Authors: Jessica Seeßle, Hongying Gan-Schreier, Marietta Kirchner, Wolfgang Stremmel, Walee Chamulitrat and Uta Merle

    Citation: BMC Gastroenterology 2020 20:230

    Content type: Research article

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  2. Adult lactase non-persistence (LNP) is due to low lactase expression, resulting in lactose malabsorption (LM). LNP is a genetic trait, but is typically determined by LM markers including breath H2, blood glucose,...

    Authors: Aahana Shrestha, Matthew P. G. Barnett, Jo K. Perry, David Cameron-Smith and Amber M. Milan

    Citation: BMC Gastroenterology 2020 20:204

    Content type: Research article

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  3. Antibiotic-associated diarrhea (AAD) occurs in 2–25% of nursing home residents, which may lead to dehydration, malnutrition, severe complications and hospitalizations. Research shows that probiotics can be eff...

    Authors: Herman A. van Wietmarschen, Martine Busch, Annemiek van Oostveen, Gerda Pot and Miek C. Jong

    Citation: BMC Gastroenterology 2020 20:151

    Content type: Research article

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  4. The relationship between metabolic syndrome (MetS) and Barrett’s esophagus (BE) is still a challenging issue, and inconsistent results have been reported in different studies. Therefore, this study was conduct...

    Authors: Mohammad Karimian, Majid Salamati and Milad Azami

    Citation: BMC Gastroenterology 2020 20:138

    Content type: Research article

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  5. The prevalence of malnutrition remains high in hospitals but no “gold standard” has been established to identify nutritional risks adequately. The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global As...

    Authors: Mariana Chávez-Tostado, Gabino Cervantes-Guevara, Sandra Estefanía López-Alvarado, Gabino Cervantes-Pérez, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Diana Mercedes Hernández-Corona, Tonatiuh González-Heredia, Guillermo Alonso Cervantes-Cardona and Alejandro González-Ojeda

    Citation: BMC Gastroenterology 2020 20:79

    Content type: Research article

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  6. The intestinal epithelial barrier allows absorption of dietary nutrients and prevents passage of pathogens and toxins into the body. Severe insults have a negative impact on the intestinal environment, which m...

    Authors: Masaaki Motoori, Koji Tanaka, Keijiro Sugimura, Hiroshi Miyata, Takuro Saito, Yasuhiro Miyazaki, Kazumasa Fujitani, Yukiko Kado, Takashi Asahara and Masahiko Yano

    Citation: BMC Gastroenterology 2020 20:74

    Content type: Research article

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  7. Hyperuricemia is a major risk for non-alcoholic fatty liver disease. However, the mechanisms for this phenomenon are not fully understood. This study aimed to investigate whether microRNAs mediated the pathoge...

    Authors: Shenghui Chen, Dan Chen, Hua Yang, Xinyu Wang, Jinghua Wang and Chengfu Xu

    Citation: BMC Gastroenterology 2020 20:39

    Content type: Research article

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  8. Enteral nutrition should be implemented as early as possible in patients with moderate or severe acute pancreatitis. This study was designed to evaluate the feasibility and Deffectiveness of ultrasound-guided ...

    Authors: Zhijun Liu, Jintao Guo, Weidong Ren, Shaoshan Tang, Ying Huang, Liping Huang, Siyu Sun and Lianjie Lin

    Citation: BMC Gastroenterology 2020 20:21

    Content type: Research article

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  9. Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathol...

    Authors: Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth, Mary Erickson, Luciano Adorini and Jacob Jelsing

    Citation: BMC Gastroenterology 2019 19:228

    Content type: Research article

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  10. Malnutrition is a common problem among children with chronic liver diseases (CLD). We aimed to assess the nutritional status of children with CLD and to correlate the anthropometric indices with the severity o...

    Authors: Nehal El Koofy, Eman Mohamed Ibraheim Moawad, Mona Fahmy, Mona Anwar Mohamed, Hany Fathy Ahmed Mohamed, Ehab Mohamed Eid, Moushira Errfan Zaki and Rokaya Mohamed El-Sayed

    Citation: BMC Gastroenterology 2019 19:223

    Content type: Research article

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  11. Alternate-day fasting (ADF) is a novel diet therapy that may achieve reduction in body weight and improvement of dyslipidaemia, but the impact of this diet on patients with non-alcoholic fatty liver disease (N...

    Authors: Hua Cai, Yue-Lan Qin, Ze-Ya Shi, Jin-Hui Chen, Min-Jie Zeng, Wei Zhou, Ru-Qun Chen and Zhi-Yuan Chen

    Citation: BMC Gastroenterology 2019 19:219

    Content type: Research article

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  12. The pathways and mechanism by which associations between the gut microbiome and the brain, termed the microbiome-gut-brain axis (MGBA), are manifest but remain to be fully elucidated. This study aims to use bi...

    Authors: Sa’ed H. Zyoud, Simon Smale, W. Stephen Waring, Waleed M. Sweileh and Samah W. Al-Jabi

    Citation: BMC Gastroenterology 2019 19:158

    Content type: Research article

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  13. The aim of the present study was to evaluate the effects of curcumin supplementation on inflammatory indices, and hepatic features in patients with non-alcoholic fatty liver disease (NAFLD).

    Authors: Saeede Saadati, Amir Sadeghi, Asieh Mansour, Zahra Yari, Hossein Poustchi, Mehdi Hedayati, Behzad Hatami and Azita Hekmatdoost

    Citation: BMC Gastroenterology 2019 19:133

    Content type: Research article

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  14. The assessment of residual gastric volume is common practice in critical care units. However, the effects and safety of discarding or returning gastric aspirates remain uncertain. Therefore, we aimed to evalua...

    Authors: Zunjia Wen, Ailing Xie, Mingqi Peng, Lanzheng Bian, Li Wei and Mei Li

    Citation: BMC Gastroenterology 2019 19:113

    Content type: Research article

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  15. Chronic autoimmune atrophic gastritis (CAAG) is an autoimmune disease characterized by hypo/achlorhydria. A role of CAAG in the pathogenesis of nutritional deficiencies has been reported, therefore we hypothes...

    Authors: Sara Massironi, Federica Cavalcoli, Alessandra Zilli, Alessandro Del Gobbo, Clorinda Ciafardini, Susanna Bernasconi, Irene Felicetta, Dario Conte and Maddalena Peracchi

    Citation: BMC Gastroenterology 2018 18:172

    Content type: Research article

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  16. Antibiotic-associated diarrhea (AAD) is a side-effect frequently associated with the use of broad spectrum antibiotics. Although a number of clinical studies show that co-administration of specific probiotics ...

    Authors: Valeria Agamennone, Cyrille A. M. Krul, Ger Rijkers and Remco Kort

    Citation: BMC Gastroenterology 2018 18:103

    Content type: Research article

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  17. Obesity is a global problem leading to reduced life expectancy, cardiovascular diseases, diabetes and many types of cancer. Even people willing to accept treatment only achieve a mean weight loss of about 5 kg...

    Authors: Marcus Hollenbach, Christiane Prettin, Felix Gundling, Wolfgang Schepp, Jochen Seufert, Jürgen Stein, Thomas Rösch, Jens Aberle, Jürgen Feisthammel, David Petroff and Albrecht Hoffmeister

    Citation: BMC Gastroenterology 2018 18:118

    Content type: Study protocol

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  18. Non-alcoholic fatty liver disease (NAFLD) comprises non-progressive steatosis and non-alcoholic steatohepatitis (NASH), the latter of which may cause cirrhosis and hepatocellular carcinoma (HCC). As NAFLD dete...

    Authors: Tilman Kühn, Tobias Nonnenmacher, Disorn Sookthai, Ruth Schübel, Daniel Antonio Quintana Pacheco, Oyunbileg von Stackelberg, Mirja E. Graf, Theron Johnson, Christopher L. Schlett, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor and Johanna Nattenmüller

    Citation: BMC Gastroenterology 2018 18:113

    Content type: Research article

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  19. Probiotics have been shown to be useful for the treatment of many disease conditions. These beneficial effects are believed to be mediated by change in the composition of gut microbiota and modulation of the h...

    Authors: Ankita Singh, Aditya N. Sarangi, Amit Goel, Rajni Srivastava, Rajat Bhargava, Priyanka Gaur, Amita Aggarwal and Rakesh Aggarwal

    Citation: BMC Gastroenterology 2018 18:85

    Content type: Research article

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  20. Non-alcoholic fatty liver disease (NAFLD) is common both in obese and overweight patients. Fibroblast growth factor 19 (FGF19), an intestinal hormone, could play a role in the complex pathogenesis of NAFLD. Th...

    Authors: Dana Friedrich, Hanns-Ulrich Marschall and Frank Lammert

    Citation: BMC Gastroenterology 2018 18:76

    Content type: Research article

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  21. Serum IgG and IgA food antibodies have been used for dietary advice to subjects with gastrointestinal symptoms and perceived food intolerance, but the role of these antibodies in mediating intolerance is contr...

    Authors: Anne Stine Kvehaugen, Dag Tveiten and Per G. Farup

    Citation: BMC Gastroenterology 2018 18:22

    Content type: Research article

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  22. Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treat...

    Authors: Maraci Rodrigues, Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro

    Citation: BMC Gastroenterology 2018 18:15

    Content type: Research article

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    The Correction to this article has been published in BMC Gastroenterology 2018 18:36

  23. Patients with gastrointestinal food allergy are characterised by increased production of mast cell derived mediators upon allergen contact and present often with unspecific symptoms. The aim of this study was ...

    Authors: Martin Raithel, Alexander Hagel, Heinz Albrecht, Yurdaguel Zopf, Andreas Naegel, Hanns-Wolf Baenkler, Fred Buchwald, Hans-Wolfgang Schultis, Juergen Kressel, Eckhart Georg Hahn and Peter Konturek

    Citation: BMC Gastroenterology 2015 15:41

    Content type: Research article

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  24. The prevalence of obesity has increased at alarming rates, particularly because of the increased consumption of high-fat diets (HFDs). The influence of HFDs on intrinsic innervation and the intestinal wall has...

    Authors: Angelica Soares, Evandro José Beraldi, Paulo Emílio Botura Ferreira, Roberto Barbosa Bazotte and Nilza Cristina Buttow

    Citation: BMC Gastroenterology 2015 15:3

    Content type: Research article

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  25. Semi-solidification by gelation or increased viscosity could slow the influx of liquid enteral nutrition (EN) into the small intestine. A liquid EN formula containing pectin that gels under acidic conditions s...

    Authors: Ippei Yamaoka, Takeshi Kikuchi, Naoyuki Endo and Goro Ebisu

    Citation: BMC Gastroenterology 2014 14:168

    Content type: Research article

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  26. WHO guidelines recommend zinc supplementation as a key adjunct therapy for childhood diarrhea in developing countries, however zinc’s anti-diarrheal effects remain only partially understood. Recently, it has b...

    Authors: Camila AA de Queiroz, Said Gonçalves C Fonseca, Priscila B Frota, Ítalo L Figueiredo, Karoline S Aragão, Carlos Emanuel C Magalhães, Cibele BM de Carvalho, Aldo Ângelo M Lima, Ronaldo A Ribeiro, Richard L Guerrant, Sean R Moore and Reinaldo B Oriá

    Citation: BMC Gastroenterology 2014 14:136

    Content type: Research article

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  27. The consequences of subclinical coeliac disease (CD) in Type 1 diabetes mellitus (T1DM) remain unclear. We looked at growth, anthropometry and disease management in children with dual diagnosis (T1DM + CD) bef...

    Authors: Mary Mackinder, Gavin Allison, Vaios Svolos, Elaine Buchanan, Alison Johnston, Tracey Cardigan, Nicola Laird, Hazel Duncan, Karen Fraser, Christine A Edwards, Ian Craigie, Paraic McGrogan and Konstantinos Gerasimidis

    Citation: BMC Gastroenterology 2014 14:99

    Content type: Research article

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  28. Fibre intake among North Americans is currently less than half the recommended amount. Consumers are interested in food products that could promote weight loss and improve health. Consequently, evaluation of u...

    Authors: Jennifer E Lambert, Jill A Parnell, Jay Han, Troy Sturzenegger, Heather A Paul, Hans J Vogel and Raylene A Reimer

    Citation: BMC Gastroenterology 2014 14:69

    Content type: Study protocol

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  29. A limited body of research suggests that ongoing maintenance enteral nutrition (MEN) can be beneficial in maintaining disease remission in Crohn’s Disease (CD). We aimed to assess how achievable MEN is and whe...

    Authors: Hazel Duncan, Elaine Buchanan, Tracey Cardigan, Vikki Garrick, Lee Curtis, Paraic McGrogan, Andrew Barclay and Richard K Russell

    Citation: BMC Gastroenterology 2014 14:50

    Content type: Research article

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  30. Recently, the relationship between gut microbiota and obesity has been highlighted. The present randomized, double-blind, placebo-controlled study aimed to evaluate the efficacy of transglucosidase (TGD) in mo...

    Authors: Makoto Sasaki, Naotaka Ogasawara, Yasushi Funaki, Mari Mizuno, Akihito Iida, Chiho Goto, Satoshi Koikeda, Kunio Kasugai and Takashi Joh

    Citation: BMC Gastroenterology 2013 13:81

    Content type: Research article

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  31. Due to the restrictive nature of a gluten-free diet, celiac patients are looking for alternative therapies. While drug-development programs include gluten challenges, knowledge regarding the duration of gluten...

    Authors: Marja-Leena Lähdeaho, Markku Mäki, Kaija Laurila, Heini Huhtala and Katri Kaukinen

    Citation: BMC Gastroenterology 2011 11:129

    Content type: Research article

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