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Intestinal disorders

This section concerns all clinical and basic science aspects of intestinal disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

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  1. There is increasing evidence for the role of microscopic inflammation in patients with IBS. We aimed to examine the prevalence of microscopic colitis and inflammation in Malaysian IBS patients with diarrhoea (...

    Authors: Ida Hilmi, Juanda Leo Hartono, Jayalakshmi Pailoor, Sanjiv Mahadeva and Khean-Lee Goh

    Citation: BMC Gastroenterology 2013 13:80

    Content type: Research article

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  2. Some studies have shown that endoscopist specialty is associated with colorectal cancers missed by colonoscopy. We sought to examine the relationship between endoscopist specialty and polypectomy rate, a colon...

    Authors: Mengzhu Jiang, Maida J Sewitch, Alan N Barkun, Lawrence Joseph and Robert J Hilsden

    Citation: BMC Gastroenterology 2013 13:78

    Content type: Research article

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  3. Influence of genetic variants in the NOD2 gene may play a more important role in disease activity, behaviour and treatment of pediatric- than adult-onset Crohn’s disease (CD).

    Authors: Carsten Posovszky, Veronika Pfalzer, Georgia Lahr, Jan Hendrik Niess, Jochen Klaus, Benjamin Mayer, Klaus-Michael Debatin and Georg BT von Boyen

    Citation: BMC Gastroenterology 2013 13:77

    Content type: Research article

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  4. Intra-abdominal infections are one of the most common infections encountered by a general surgeon. However, despite this prevalence, standardized guidelines outlining the proper use of antibiotic therapy are p...

    Authors: Fausto Catena, Carlo Vallicelli, Luca Ansaloni, Massimo Sartelli, Salomone Di Saverio, Riccardo Schiavina, Eddi Pasqualini, Annalisa Amaduzzi, Federico Coccolini, Michele Cucchi, Daniel Lazzareschi, Gian Luca Baiocchi and Antonio D Pinna

    Citation: BMC Gastroenterology 2013 13:76

    Content type: Research article

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  5. Evidence suggests that many coeliac disease patients suffer from persistent clinical symptoms and reduced health-related quality of life despite a strict gluten-free diet. We aimed to find predictors for these...

    Authors: Pilvi Paarlahti, Kalle Kurppa, Anniina Ukkola, Pekka Collin, Heini Huhtala, Markku Mäki and Katri Kaukinen

    Citation: BMC Gastroenterology 2013 13:75

    Content type: Research article

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  6. Chronic diarrhea in adults is a common symptom with a wide range of underlying etiologies. Although various strategies have been proposed for evaluation, there are still cases with undetermined origins even af...

    Authors: Chen Wang, Yue Li, Yali Jin, Weixun Zhou, Yanlin Zhu, Fang Yao and Jiaming Qian

    Citation: BMC Gastroenterology 2013 13:71

    Content type: Case report

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  7. Intestinal ischemia-reperfusion injury (IRI) can occur in clinical scenarios such as organ transplantation, trauma and cardio-pulmonary bypass, as well as in neonatal necrotizing enterocolitis or persistent du...

    Authors: Steven SC Cho, Ina Rudloff, Philip J Berger, Michael G Irwin, Marcel F Nold, Wei Cheng and Claudia A Nold-Petry

    Citation: BMC Gastroenterology 2013 13:69

    Content type: Research article

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  8. Many patients with IBS suffer on-going symptoms. The evidence base is poor for IBS drugs but they are widely prescribed and advised in Guidelines. Cognitive Behavioural Therapy (CBT) can be helpful, but availa...

    Authors: Hazel Everitt, Rona Moss-Morris, Alice Sibelli, Laura Tapp, Nicholas Coleman, Lucy Yardley, Peter Smith and Paul Little

    Citation: BMC Gastroenterology 2013 13:68

    Content type: Research article

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  9. This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or...

    Authors: Magdalena Pilarczyk-Zurek, Agnieszka Chmielarczyk, Tomasz Gosiewski, Anna Tomusiak, Pawel Adamski, Malgorzata Zwolinska-Wcislo, Tomasz Mach, Piotr B Heczko and Magdalena Strus

    Citation: BMC Gastroenterology 2013 13:61

    Content type: Research article

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  10. Orbital myositis is a rare extra-intestinal manifestation of inflammatory bowel disease. Seventeen cases of Crohn’s disease associated orbital myositis and 3 cases of ulcerative colitis associated orbital myos...

    Authors: Sanam Verma, Karen I Kroeker and Richard N Fedorak

    Citation: BMC Gastroenterology 2013 13:59

    Content type: Case report

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  11. Inflammatory bowel diseases (IBD) are chronic diseases of unknown etiology and pathogenesis in which genetic factors contribute to development of disease. MDR1/ABCB1 is an interesting candidate gene for IBD. The ...

    Authors: Marko Brinar, Silvija Cukovic-Cavka, Nada Bozina, Katja Grubelic Ravic, Pave Markos, Agata Ladic, Marijana Cota, Zeljko Krznaric and Boris Vucelic

    Citation: BMC Gastroenterology 2013 13:57

    Content type: Research article

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  12. Constipation is one of the most common gastrointestinal complaints with a highly prevalent and often chronic functional gastrointestinal disorder affecting health-related quality of life. The aim of the presen...

    Authors: Mengyi Zhou, Ping Jia, Jinping Chen, Aihui Xiu, Yue Zhao, Yibei Zhan, Peng Chen and Jianfa Zhang

    Citation: BMC Gastroenterology 2013 13:52

    Content type: Research article

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  13. The US CDC estimates over 2 million foodborne illnesses are annually caused by 4 major enteropathogens: non-typhoid Salmonella spp., Campylobacter spp., Shigella spp. and Yersinia enterocoltica. While data sugges...

    Authors: Chad K Porter, Daniel Choi, Brooks Cash, Mark Pimentel, Joseph Murray, Larissa May and Mark S Riddle

    Citation: BMC Gastroenterology 2013 13:46

    Content type: Research article

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  14. Irritable Bowel Syndrome (IBS) is a common condition characterised by pain, distension and altered bowel habit. Evidence suggests functional foods containing probiotics improve gastrointestinal transit, howeve...

    Authors: Lesley M Roberts, Deborah McCahon, Roger Holder, Sue Wilson and FD Richard Hobbs

    Citation: BMC Gastroenterology 2013 13:45

    Content type: Research article

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  15. Microscopic polyangiitis is characterized by pauci-immune, necrotizing small-vessel vasculitis and an anti-neutrophil cytoplasmic antibody-associated vasculitis. Although gastrointestinal involvement in micros...

    Authors: Masashi Fukushima, Satoko Inoue, Yuichiro Ono, Yoshitaka Tamaki, Hajime Yoshimura, Yukihiro Imai and Tetsuro Inokuma

    Citation: BMC Gastroenterology 2013 13:42

    Content type: Case report

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  16. Patients with ulcerative colitis (UC) are treated with prednisolone (PSL), which causes adverse side effects. Extracorporeal granulocyte/monocyte adsorption (GMA) with an Adacolumn depletes elevated/activated ...

    Authors: Keiichi Tominaga, Masakazu Nakano, Mina Hoshino, Kazunari Kanke and Hideyuki Hiraishi

    Citation: BMC Gastroenterology 2013 13:41

    Content type: Research article

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  17. Patients with persistent symptoms and/or villous atrophy despite strict adherence to a gluten-free diet (GFD) have non-responsive celiac disease (NRCD). A subset of these patients has refractory celiac disease...

    Authors: Justin R Hollon, Pamela A Cureton, Margaret L Martin, Elaine L Leonard Puppa and Alessio Fasano

    Citation: BMC Gastroenterology 2013 13:40

    Content type: Research article

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  18. A high prevalence of chronic fatigue has previously been reported following giardiasis after a large waterborne outbreak in Bergen, Norway in 2004. The aim of this study was to describe and evaluate differenti...

    Authors: Kristine Mørch, Kurt Hanevik, Ann C Rivenes, Jørn E Bødtker, Halvor Næss, Bjarte Stubhaug, Knut-Arne Wensaas, Guri Rortveit, Geir E Eide, Trygve Hausken and Nina Langeland

    Citation: BMC Gastroenterology 2013 13:28

    Content type: Research article

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  19. Adsorptive granulocyte and monocyte apheresis (GMA) with an Adacolumn in patients with ulcerative colitis (UC) has been applied as a non-pharmacological treatment strategy, but the efficacy has been encouragin...

    Authors: Yoko Yokoyama, Mikio Kawai, Ken Fukunaga, Koji Kamikozuru, Kazuko Nagase, Koji Nogami, Tomoaki Kono, Yoshio Ohda, Masaki Iimuro, Nobuyuki Hida, Shiro Nakamura, Hiroto Miwa and Takayuki Matsumoto

    Citation: BMC Gastroenterology 2013 13:27

    Content type: Research article

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  20. The cavitating mesenteric lymph node syndrome (CMLNS) is a rare manifestation of celiac disease, with an estimated mortality rate of 50%. Specific infections and malignant lymphoma may complicate its clinical ...

    Authors: Cristina Pojoga, Lidia Ciobanu, Alexandru Florin Badea, Emil Boţan, Cosmin Caraiani, Claudia Hagiu, Grigore Băciuţ and Radu Badea

    Citation: BMC Gastroenterology 2013 13:26

    Content type: Case report

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  21. Although high non-adherence to medication has been noticed for ulcerative colitis (UC), little is known about adherence to mesalamine treatments and determinants that can predict adherence. The objective of th...

    Authors: Jean Lachaine, Linnette Yen, Catherine Beauchemin and Paul Hodgkins

    Citation: BMC Gastroenterology 2013 13:23

    Content type: Research article

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  22. Alterations in the fecal bacterial flora occur in inflammatory bowel disease (IBD). We examined the abundance and diversity of Clostridium leptum group, an important group of carbohydrate-fermenting bacteria, in ...

    Authors: Jayakanthan Kabeerdoss, Vijayalakshmi Sankaran, Srinivasan Pugazhendhi and Balakrishnan S Ramakrishna

    Citation: BMC Gastroenterology 2013 13:20

    Content type: Research article

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  23. Internet websites are a resource for patients seeking information about probiotics. We examined a sample of 71 websites presenting probiotic information. We found that descriptions of benefits far outnumbered ...

    Authors: Margaret A Brinich, Mary Beth Mercer and Richard R Sharp

    Citation: BMC Gastroenterology 2013 13:5

    Content type: Correspondence

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  24. There is lack of data on prevalence of celiac disease (CD) in children with type 1 diabetes (T1D) in Arabs in the Middle East. The present investigation aims to study the prevalence rate and clinical character...

    Authors: Abdulrahman Al-Hussaini, Nimer Sulaiman, Musa Al-Zahrani, Ahmed Alenizi and Imad El Haj

    Citation: BMC Gastroenterology 2012 12:180

    Content type: Research article

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  25. Gastrointestinal dysmotility may be involved in the development of bacterial translocation and infection in patients with liver cirrhosis. The aim of the present study was to describe gastric, small intestinal...

    Authors: Stine Karlsen, Lotte Fynne, Henning Grønbæk and Klaus Krogh

    Citation: BMC Gastroenterology 2012 12:176

    Content type: Research article

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  26. Patients with Crohn’s disease (CD) have been shown to present dyspeptic symptoms more frequently than the general population. Some of these symptoms could be related to motility disorders to some degree. Then,...

    Authors: Ana Carolina Mello Nóbrega, Bruno Roberto Silva Ferreira, Graciela Josué Oliveira, Kamila Maria Oliveira Sales, Armênio Aguiar Santos, Miguel Ângelo Nobre e Souza, Lúcia Libanês Bessa Campelo Braga, Luizde Almeida Ernesto de Almeida Troncon and Marcellus Henrique Loiola Ponte Souza

    Citation: BMC Gastroenterology 2012 12:175

    Content type: Research article

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  27. Induced regulatory T (iTreg) lymphocytes show promise for application in the treatment of allergic, autoimmune and inflammatory disorders. iTreg cells demonstrate advantages over natural Treg (nTreg) cells in ...

    Authors: Anna Majowicz, Sander van der Marel, Anje A te Velde, Sybren L Meijer, Harald Petry, Sander J van Deventer and Valerie Ferreira

    Citation: BMC Gastroenterology 2012 12:172

    Content type: Research article

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  28. Patients with Irritable Bowel Syndrome (IBS) often relate their symptoms to the intake of food and modify their diet. IgE-mediated food allergy is uncommon in IBS, but the role of IgG-mediated food hypersensit...

    Authors: Solveig C Ligaarden, Stian Lydersen and Per G Farup

    Citation: BMC Gastroenterology 2012 12:166

    Content type: Research article

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  29. To compare the characteristics between 22-channel water-perfusion manometry (WPM) and solid-state manometry (SSM) with 36 sensors of the pressure measurements, as well as patients’ discomfort indices in nose a...

    Authors: Kun Wang, Li-ping Duan, Ying Ge, Zhi-wei Xia and Zhi-jie Xu

    Citation: BMC Gastroenterology 2012 12:157

    Content type: Research article

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  30. Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE1) used for chronic constipation. The best known action of lubiprostone is simulation of Cl- dependent fluid secretion. In a mous...

    Authors: Robert C De Lisle

    Citation: BMC Gastroenterology 2012 12:156

    Content type: Research article

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  31. Pancreatic Stone Protein (PSP) is a protein naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that blood PSP levels rise in the presence of inflamma...

    Authors: Christoph Tschuor, Dimitri Aristotle Raptis, Përparim Limani, Thomas Bächler, Christian Eugen Oberkofler, Stefan Breitenstein and Rolf Graf

    Citation: BMC Gastroenterology 2012 12:154

    Content type: Study protocol

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  32. Sleep disturbances are increasingly recognized as a common problem for children and adolescents with chronic pain conditions, but little is known about the prevalence, type, and impact of sleep problems in ped...

    Authors: Jennifer Verrill Schurman, Craig A Friesen, Hongying Dai, Caroline Elder Danda, Paul E Hyman and Jose T Cocjin

    Citation: BMC Gastroenterology 2012 12:142

    Content type: Research article

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  33. Observational cohort study to assess the association between adherence to oral 5-aminosalicylates (5-ASAs) and all-cause costs and health care utilization among patients with active ulcerative colitis (UC) in ...

    Authors: Debanjali Mitra, Paul Hodgkins, Linnette Yen, Keith L Davis and Russell D Cohen

    Citation: BMC Gastroenterology 2012 12:132

    Content type: Research article

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  34. Short bowel syndrome (SBS) may induce a plethora of clinical symptoms ranging from underweight to nutrient-, vitamin- and electrolyte deficiencies. The objective of this case report is to illustrate how demand...

    Authors: Markus Hahn, Martin Raithel, Alexander Hagel, Teresa Biermann and Bernhard Manger

    Citation: BMC Gastroenterology 2012 12:129

    Content type: Case report

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  35. Patients with irritable bowel syndrome (IBS) seen by a gastroenterologist often utilize medications that may alter intestinal homeostasis. The question arises whether exposure to these drugs is associated with...

    Authors: Daniel Keszthelyi, Gwen H Dackus, Gwen M Masclee, Joanna W Kruimel and Ad AM Masclee

    Citation: BMC Gastroenterology 2012 12:121

    Content type: Research article

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  36. The instrument channels of gastrointestinal (GI) endoscopes may be heavily contaminated with bacteria even after high-level disinfection (HLD). The British Society of Gastroenterology guidelines emphasize the ...

    Authors: King-Wah Chiu, Ming-Chao Tsai, Keng-Liang Wu, Yi-Chun Chiu, Ming-Tzung Lin and Tsung-Hui Hu

    Citation: BMC Gastroenterology 2012 12:120

    Content type: Research article

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  37. Mice lacking Foxp3+ regulatory T (Treg) cells develop severe tissue inflammation in lung, skin, and liver with premature death, whereas the intestine remains uninflamed. This study aims to demonstrate the importa...

    Authors: Franziska Boehm, Maria Martin, Rebecca Kesselring, Gabriela Schiechl, Edward K Geissler, Hans-Jürgen Schlitt and Stefan Fichtner-Feigl

    Citation: BMC Gastroenterology 2012 12:97

    Content type: Research article

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  38. Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mecha...

    Authors: Martin Steinkamp, Heike Gundel, Nadine Schulte, Ulrike Spaniol, Carolin Pflueger, Eugen Zizer and Georg BT von Boyen

    Citation: BMC Gastroenterology 2012 12:6

    Content type: Research article

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  39. The evaluation of patients with abdominal discomfort is challenging and patient selection for endoscopy based on symptoms is not reliable. We evaluated the diagnostic value of fecal calprotectin in patients wi...

    Authors: Michael Manz, Emanuel Burri, Claude Rothen, Nuschin Tchanguizi, Christian Niederberger, Livio Rossi, Christoph Beglinger and Frank Serge Lehmann

    Citation: BMC Gastroenterology 2012 12:5

    Content type: Research article

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  40. The utility of serologic screening for celiac disease is still debatable. Evidence suggests that the disorder remains undetected even in the older population. It remains obscure whether screening makes good or...

    Authors: Anitta Vilppula, Katri Kaukinen, Liisa Luostarinen, Ilkka Krekelä, Heikki Patrikainen, Raisa Valve, Markku Luostarinen, Kaija Laurila, Markku Mäki and Pekka Collin

    Citation: BMC Gastroenterology 2011 11:136

    Content type: Research article

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  41. Irritable bowel syndrome (IBS) and gastrointestinal (GI) dysmotility disorders have a similar clinical picture, although dysmotility disorders require the attention of a specialist. Patients with primary Sjögr...

    Authors: Mariette Bengtsson, Oskar Hammar, Thomas Mandl and Bodil Ohlsson

    Citation: BMC Gastroenterology 2011 11:122

    Content type: Research article

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  42. Constipation severity is often defined by symptoms including feelings of complete evacuation, straining, stool frequency and consistency. These descriptors are mostly obtained in the absence of laxative use. F...

    Authors: Phil G Dinning, Linda Hunt, David Z Lubowski, Jamshid S Kalantar, Ian J Cook and Mike P Jones

    Citation: BMC Gastroenterology 2011 11:121

    Content type: Research article

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  43. Several techniques have been described for the management of fistula-in-ano, but all carry their own risks of recurrence and incontinence. We conducted a prospective study to assess type of presentation, treat...

    Authors: Pierpaolo Sileri, Federica Cadeddu, Stefano D'Ugo, Luana Franceschilli, Giovanna Del Vecchio Blanco, Elisabetta De Luca, Emma Calabrese, Sara Mara Capperucci, Valeria Fiaschetti, Giovanni Milito and Achille Lucio Gaspari

    Citation: BMC Gastroenterology 2011 11:120

    Content type: Research article

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  44. To determine how the delay in diagnosing celiac disease (CD) has developed during recent decades and how this affects the burden of disease in terms of health-related quality of life (HRQoL), and also to consi...

    Authors: Fredrik Norström, Lars Lindholm, Olof Sandström, Katrina Nordyke and Anneli Ivarsson

    Citation: BMC Gastroenterology 2011 11:118

    Content type: Research article

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  45. Using standard diagnostic algorithms it is not always possible to establish the correct phenotype of inflammatory bowel disease which is essential for therapeutical decisions. Endoscopic ultrasound elastograph...

    Authors: Nadan Rustemovic, Silvija Cukovic-Cavka, Marko Brinar, Davor Radić, Milorad Opacic, Rajko Ostojic and Boris Vucelic

    Citation: BMC Gastroenterology 2011 11:113

    Content type: Research article

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  46. Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarr...

    Authors: Rainer Noth, Julia Lange-Grumfeld, Eckhard Stüber, Marie-Luise Kruse, Mark Ellrichmann, Robert Häsler, Jochen Hampe, Burkhard Bewig, Philip Rosenstiel, Stefan Schreiber and Alexander Arlt

    Citation: BMC Gastroenterology 2011 11:109

    Content type: Research article

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  47. Irritable bowel syndrome (IBS) is a chronic functional bowel disorder. The frequency of microscopic colitis and focal active colitis in the colonic mucosa has been investigated in IBS patients.

    Authors: Kamil Ozdil, Abdurrahman Sahin, Turan Calhan, Resul Kahraman, Adil Nigdelioglu, Umit Akyuz and Hacı M Sokmen

    Citation: BMC Gastroenterology 2011 11:96

    Content type: Research article

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  48. Methotrexate treatment has been associated to intestinal epithelial damage. Studies have suggested an important role of nitric oxide in such injury. The aim of this study was to investigate the role of nitric ...

    Authors: Renata FC Leitão, Gerly AC Brito, Reinaldo B Oriá, Manuel B Braga-Neto, Emmanuelle AL Bellaguarda, Johann V Silva, Antoniella S Gomes, Roberto CP Lima-Júnior, Francisco JWS Siqueira, Rosemeyre S Freire, Mariana L Vale and Ronaldo A Ribeiro

    Citation: BMC Gastroenterology 2011 11:90

    Content type: Research article

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  49. Ileal intubation is the gold standard for a complete colonoscopy. However, despite evidence of clinical benefit ileoscopy is not always attempted due to perceived technical difficulty. Our aim was to compare t...

    Authors: Arjuna P De Silva, Ravindu S Kumarasena, Suramya D Perera Keragala, Udaya Kalubowila, Madunil Niriella, Anuradha S Dassanayake, Arunasalam Pathmeswaran and H Janaka de Silva

    Citation: BMC Gastroenterology 2011 11:89

    Content type: Research article

    Published on:

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BMC Gastroenterology

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