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Intestinal disorders

Section edited by Peter Lakatos

This section concerns all clinical and basic science aspects of intestinal disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

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  1. Alterations in the fecal bacterial flora occur in inflammatory bowel disease (IBD). We examined the abundance and diversity of Clostridium leptum group, an important group of carbohydrate-fermenting bacteria, in ...

    Authors: Jayakanthan Kabeerdoss, Vijayalakshmi Sankaran, Srinivasan Pugazhendhi and Balakrishnan S Ramakrishna

    Citation: BMC Gastroenterology 2013 13:20

    Content type: Research article

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  2. Internet websites are a resource for patients seeking information about probiotics. We examined a sample of 71 websites presenting probiotic information. We found that descriptions of benefits far outnumbered ...

    Authors: Margaret A Brinich, Mary Beth Mercer and Richard R Sharp

    Citation: BMC Gastroenterology 2013 13:5

    Content type: Correspondence

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  3. There is lack of data on prevalence of celiac disease (CD) in children with type 1 diabetes (T1D) in Arabs in the Middle East. The present investigation aims to study the prevalence rate and clinical character...

    Authors: Abdulrahman Al-Hussaini, Nimer Sulaiman, Musa Al-Zahrani, Ahmed Alenizi and Imad El Haj

    Citation: BMC Gastroenterology 2012 12:180

    Content type: Research article

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  4. Gastrointestinal dysmotility may be involved in the development of bacterial translocation and infection in patients with liver cirrhosis. The aim of the present study was to describe gastric, small intestinal...

    Authors: Stine Karlsen, Lotte Fynne, Henning Grønbæk and Klaus Krogh

    Citation: BMC Gastroenterology 2012 12:176

    Content type: Research article

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  5. Patients with Crohn’s disease (CD) have been shown to present dyspeptic symptoms more frequently than the general population. Some of these symptoms could be related to motility disorders to some degree. Then,...

    Authors: Ana Carolina Mello Nóbrega, Bruno Roberto Silva Ferreira, Graciela Josué Oliveira, Kamila Maria Oliveira Sales, Armênio Aguiar Santos, Miguel Ângelo Nobre e Souza, Lúcia Libanês Bessa Campelo Braga, Luizde Almeida Ernesto de Almeida Troncon and Marcellus Henrique Loiola Ponte Souza

    Citation: BMC Gastroenterology 2012 12:175

    Content type: Research article

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  6. Induced regulatory T (iTreg) lymphocytes show promise for application in the treatment of allergic, autoimmune and inflammatory disorders. iTreg cells demonstrate advantages over natural Treg (nTreg) cells in ...

    Authors: Anna Majowicz, Sander van der Marel, Anje A te Velde, Sybren L Meijer, Harald Petry, Sander J van Deventer and Valerie Ferreira

    Citation: BMC Gastroenterology 2012 12:172

    Content type: Research article

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  7. Patients with Irritable Bowel Syndrome (IBS) often relate their symptoms to the intake of food and modify their diet. IgE-mediated food allergy is uncommon in IBS, but the role of IgG-mediated food hypersensit...

    Authors: Solveig C Ligaarden, Stian Lydersen and Per G Farup

    Citation: BMC Gastroenterology 2012 12:166

    Content type: Research article

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  8. To compare the characteristics between 22-channel water-perfusion manometry (WPM) and solid-state manometry (SSM) with 36 sensors of the pressure measurements, as well as patients’ discomfort indices in nose a...

    Authors: Kun Wang, Li-ping Duan, Ying Ge, Zhi-wei Xia and Zhi-jie Xu

    Citation: BMC Gastroenterology 2012 12:157

    Content type: Research article

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  9. Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE1) used for chronic constipation. The best known action of lubiprostone is simulation of Cl- dependent fluid secretion. In a mous...

    Authors: Robert C De Lisle

    Citation: BMC Gastroenterology 2012 12:156

    Content type: Research article

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  10. Pancreatic Stone Protein (PSP) is a protein naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that blood PSP levels rise in the presence of inflamma...

    Authors: Christoph Tschuor, Dimitri Aristotle Raptis, Përparim Limani, Thomas Bächler, Christian Eugen Oberkofler, Stefan Breitenstein and Rolf Graf

    Citation: BMC Gastroenterology 2012 12:154

    Content type: Study protocol

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  11. Sleep disturbances are increasingly recognized as a common problem for children and adolescents with chronic pain conditions, but little is known about the prevalence, type, and impact of sleep problems in ped...

    Authors: Jennifer Verrill Schurman, Craig A Friesen, Hongying Dai, Caroline Elder Danda, Paul E Hyman and Jose T Cocjin

    Citation: BMC Gastroenterology 2012 12:142

    Content type: Research article

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  12. Observational cohort study to assess the association between adherence to oral 5-aminosalicylates (5-ASAs) and all-cause costs and health care utilization among patients with active ulcerative colitis (UC) in ...

    Authors: Debanjali Mitra, Paul Hodgkins, Linnette Yen, Keith L Davis and Russell D Cohen

    Citation: BMC Gastroenterology 2012 12:132

    Content type: Research article

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  13. Short bowel syndrome (SBS) may induce a plethora of clinical symptoms ranging from underweight to nutrient-, vitamin- and electrolyte deficiencies. The objective of this case report is to illustrate how demand...

    Authors: Markus Hahn, Martin Raithel, Alexander Hagel, Teresa Biermann and Bernhard Manger

    Citation: BMC Gastroenterology 2012 12:129

    Content type: Case report

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  14. Patients with irritable bowel syndrome (IBS) seen by a gastroenterologist often utilize medications that may alter intestinal homeostasis. The question arises whether exposure to these drugs is associated with...

    Authors: Daniel Keszthelyi, Gwen H Dackus, Gwen M Masclee, Joanna W Kruimel and Ad AM Masclee

    Citation: BMC Gastroenterology 2012 12:121

    Content type: Research article

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  15. The instrument channels of gastrointestinal (GI) endoscopes may be heavily contaminated with bacteria even after high-level disinfection (HLD). The British Society of Gastroenterology guidelines emphasize the ...

    Authors: King-Wah Chiu, Ming-Chao Tsai, Keng-Liang Wu, Yi-Chun Chiu, Ming-Tzung Lin and Tsung-Hui Hu

    Citation: BMC Gastroenterology 2012 12:120

    Content type: Research article

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  16. Mice lacking Foxp3+ regulatory T (Treg) cells develop severe tissue inflammation in lung, skin, and liver with premature death, whereas the intestine remains uninflamed. This study aims to demonstrate the importa...

    Authors: Franziska Boehm, Maria Martin, Rebecca Kesselring, Gabriela Schiechl, Edward K Geissler, Hans-Jürgen Schlitt and Stefan Fichtner-Feigl

    Citation: BMC Gastroenterology 2012 12:97

    Content type: Research article

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  17. Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mecha...

    Authors: Martin Steinkamp, Heike Gundel, Nadine Schulte, Ulrike Spaniol, Carolin Pflueger, Eugen Zizer and Georg BT von Boyen

    Citation: BMC Gastroenterology 2012 12:6

    Content type: Research article

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  18. The evaluation of patients with abdominal discomfort is challenging and patient selection for endoscopy based on symptoms is not reliable. We evaluated the diagnostic value of fecal calprotectin in patients wi...

    Authors: Michael Manz, Emanuel Burri, Claude Rothen, Nuschin Tchanguizi, Christian Niederberger, Livio Rossi, Christoph Beglinger and Frank Serge Lehmann

    Citation: BMC Gastroenterology 2012 12:5

    Content type: Research article

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  19. The utility of serologic screening for celiac disease is still debatable. Evidence suggests that the disorder remains undetected even in the older population. It remains obscure whether screening makes good or...

    Authors: Anitta Vilppula, Katri Kaukinen, Liisa Luostarinen, Ilkka Krekelä, Heikki Patrikainen, Raisa Valve, Markku Luostarinen, Kaija Laurila, Markku Mäki and Pekka Collin

    Citation: BMC Gastroenterology 2011 11:136

    Content type: Research article

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  20. Irritable bowel syndrome (IBS) and gastrointestinal (GI) dysmotility disorders have a similar clinical picture, although dysmotility disorders require the attention of a specialist. Patients with primary Sjögr...

    Authors: Mariette Bengtsson, Oskar Hammar, Thomas Mandl and Bodil Ohlsson

    Citation: BMC Gastroenterology 2011 11:122

    Content type: Research article

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  21. Constipation severity is often defined by symptoms including feelings of complete evacuation, straining, stool frequency and consistency. These descriptors are mostly obtained in the absence of laxative use. F...

    Authors: Phil G Dinning, Linda Hunt, David Z Lubowski, Jamshid S Kalantar, Ian J Cook and Mike P Jones

    Citation: BMC Gastroenterology 2011 11:121

    Content type: Research article

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  22. Several techniques have been described for the management of fistula-in-ano, but all carry their own risks of recurrence and incontinence. We conducted a prospective study to assess type of presentation, treat...

    Authors: Pierpaolo Sileri, Federica Cadeddu, Stefano D'Ugo, Luana Franceschilli, Giovanna Del Vecchio Blanco, Elisabetta De Luca, Emma Calabrese, Sara Mara Capperucci, Valeria Fiaschetti, Giovanni Milito and Achille Lucio Gaspari

    Citation: BMC Gastroenterology 2011 11:120

    Content type: Research article

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  23. To determine how the delay in diagnosing celiac disease (CD) has developed during recent decades and how this affects the burden of disease in terms of health-related quality of life (HRQoL), and also to consi...

    Authors: Fredrik Norström, Lars Lindholm, Olof Sandström, Katrina Nordyke and Anneli Ivarsson

    Citation: BMC Gastroenterology 2011 11:118

    Content type: Research article

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  24. Using standard diagnostic algorithms it is not always possible to establish the correct phenotype of inflammatory bowel disease which is essential for therapeutical decisions. Endoscopic ultrasound elastograph...

    Authors: Nadan Rustemovic, Silvija Cukovic-Cavka, Marko Brinar, Davor Radić, Milorad Opacic, Rajko Ostojic and Boris Vucelic

    Citation: BMC Gastroenterology 2011 11:113

    Content type: Research article

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  25. Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarr...

    Authors: Rainer Noth, Julia Lange-Grumfeld, Eckhard Stüber, Marie-Luise Kruse, Mark Ellrichmann, Robert Häsler, Jochen Hampe, Burkhard Bewig, Philip Rosenstiel, Stefan Schreiber and Alexander Arlt

    Citation: BMC Gastroenterology 2011 11:109

    Content type: Research article

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  26. Irritable bowel syndrome (IBS) is a chronic functional bowel disorder. The frequency of microscopic colitis and focal active colitis in the colonic mucosa has been investigated in IBS patients.

    Authors: Kamil Ozdil, Abdurrahman Sahin, Turan Calhan, Resul Kahraman, Adil Nigdelioglu, Umit Akyuz and Hacı M Sokmen

    Citation: BMC Gastroenterology 2011 11:96

    Content type: Research article

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  27. Methotrexate treatment has been associated to intestinal epithelial damage. Studies have suggested an important role of nitric oxide in such injury. The aim of this study was to investigate the role of nitric ...

    Authors: Renata FC Leitão, Gerly AC Brito, Reinaldo B Oriá, Manuel B Braga-Neto, Emmanuelle AL Bellaguarda, Johann V Silva, Antoniella S Gomes, Roberto CP Lima-Júnior, Francisco JWS Siqueira, Rosemeyre S Freire, Mariana L Vale and Ronaldo A Ribeiro

    Citation: BMC Gastroenterology 2011 11:90

    Content type: Research article

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  28. Ileal intubation is the gold standard for a complete colonoscopy. However, despite evidence of clinical benefit ileoscopy is not always attempted due to perceived technical difficulty. Our aim was to compare t...

    Authors: Arjuna P De Silva, Ravindu S Kumarasena, Suramya D Perera Keragala, Udaya Kalubowila, Madunil Niriella, Anuradha S Dassanayake, Arunasalam Pathmeswaran and H Janaka de Silva

    Citation: BMC Gastroenterology 2011 11:89

    Content type: Research article

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