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Intestinal disorders

Section edited by Peter Lakatos

This section concerns all clinical and basic science aspects of intestinal disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

Page 1 of 6

  1. Content type: Research article

    Inflammatory Bowel Disease (IBD) with its high incidence and prevalence rates in Canada generates a heavy burden of tests and procedures. The purpose of this study is to gain a better understanding of the tran...

    Authors: Isabelle Noiseux, Sophie Veilleux, Alain Bitton, Rita Kohen, Luc Vachon, Brian White Guay and John D. Rioux

    Citation: BMC Gastroenterology 2019 19:30

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  2. Content type: Research article

    Overweight and metabolic problems now add to the burden of illness in patients with Inflammatory Bowel Disease. We aimed to determine if a program of aerobic and resistance exercise could safely achieve body c...

    Authors: Owen Cronin, Wiley Barton, Carthage Moran, Donal Sheehan, Ronan Whiston, Helena Nugent, Yvonne McCarthy, Catherine B. Molloy, Orla O’Sullivan, Paul D. Cotter, Michael G. Molloy and Fergus Shanahan

    Citation: BMC Gastroenterology 2019 19:29

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  3. Content type: Case report

    Superior mesenteric artery (SMA) syndrome, also known as Wilkie’s syndrome or Benign duodenal stasis, is a rare benign disease. It could threaten the life if the manifestation is severe and the treatment is in...

    Authors: Ying Shi, Guangya Shi, Zhenyu Li, Yanfang Chen, Shaohui Tang and Wei Huang

    Citation: BMC Gastroenterology 2019 19:15

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  4. Content type: Research article

    Health administrative data is increasingly used to conduct population-based health services research. A major limitation of these data for the study of inflammatory bowel diseases is the absence of detailed cl...

    Authors: Sanjay K. Murthy, Tushar Shukla, Lilia Antonova, Marc-Andre Belair, Tim Ramsay, Zane Gallinger, Geoffrey C. Nguyen and Eric I. Benchimol

    Citation: BMC Gastroenterology 2019 19:13

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  5. Content type: Case report

    Encapsulating peritoneal sclerosis (EPS) is a chronic clinical syndrome of acute or subacute gastrointestinal obstruction seen mainly in patients undergoing peritoneal dialysis. Although there are a few report...

    Authors: Yoshimitsu Shimomura, Shinsuke Sakai, Hiroyuki Ueda, Kohei Fujikura, Yukihiro Imai and Takayuki Ishikawa

    Citation: BMC Gastroenterology 2019 19:12

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  6. Content type: Case report

    Mitochondrial neurogastrointestinal encephalopathy (MNGIE), due to mutations in TYMP, often presents with gastrointestinal symptoms. Two sisters, initially managed for Crohn’s disease based upon clinical, imaging...

    Authors: Ravi Patel, Lucia Lee Coulter, Joanna Rimmer, Miles Parkes, Patrick Francis Chinnery and Oscar Swift

    Citation: BMC Gastroenterology 2019 19:11

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  7. Content type: Research article

    Recent studies have found gut microbiota to be closely associated with onset and perpetuation of UC. Currently, studies about gut microbiota have mainly covered samples collected from the intestinal lumen. How...

    Authors: Ling-yan Pei, Yu-shi Ke, Huan-hu Zhao, Lin Wang, Chao Jia, Wei-zhi Liu, Qian-hui Fu, Meng-ni Shi, Jian Cui and Shu-chun Li

    Citation: BMC Gastroenterology 2019 19:10

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  8. Content type: Case report

    Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous disorder that manifests oculocutaneous albinism together with bleeding diatheses that reflect a platelet storage pool deficiency. Ten geneti...

    Authors: Jun Ishihara, Tatsuki Mizuochi, Takashi Uchida, Yugo Takaki, Ken-ichiro Konishi, Masahiko Joo, Yasuhiko Takahashi, Shinichiro Yoshioka, Hironori Kusano, Yoji Sasahara and Yushiro Yamashita

    Citation: BMC Gastroenterology 2019 19:9

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  9. Content type: Research article

    The incidence of Ulcerative colitis (UC) in Asia is increasing but reports on its long-term course are few. The aim of this study was to identify risk factors predictive of extent progression in Asian patients...

    Authors: Yun Qiu, Baili Chen, Yufei Li, Shanshan Xiong, Shenghong Zhang, Yao He, Zhirong Zeng, Shomron Ben-Horin, Minhu Chen and Ren Mao

    Citation: BMC Gastroenterology 2019 19:7

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  10. Content type: Database

    Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these in...

    Authors: Floris Imhann, K. J. Van der Velde, R. Barbieri, R. Alberts, M. D. Voskuil, A. Vich Vila, V. Collij, L. M. Spekhorst, Van der Sloot KWJ, V. Peters, H. M. Van Dullemen, M. C. Visschedijk, Festen EAM, M. A. Swertz, G. Dijkstra and R. K. Weersma

    Citation: BMC Gastroenterology 2019 19:5

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  11. Content type: Research article

    We aimed to investigate how high-dose ecabet sodium affects low-dose aspirin-induced small intestinal mucosal injury in healthy volunteers.

    Authors: Kazuhiro Ota, Toshihisa Takeuchi, Yuichi Kojima, Satoshi Harada, Yuki Hirata, Noriaki Sugawara, Sadaharu Nouda, Kazuki Kakimoto, Takanori Kuramoto and Kazuhide Higuchi

    Citation: BMC Gastroenterology 2019 19:4

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  12. Content type: Research article

    Many reports have documented the increasing impact of Clostridium difficile infection (CDI) in patients with ulcerative colitis (UC). We conducted a retrospective study to determine the incidence, clinical charac...

    Authors: Hui Xu, Hao Tang, Tao Xu, Meng Xiao, Ji Li, Bei Tan, Hong Yang, Hong Lv, Yue Li and Jiaming Qian

    Citation: BMC Gastroenterology 2019 19:3

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  13. Content type: Research article

    Tissue inflammation in inflammatory bowel diseases (IBD) is associated with a decrease in local pH. The gene encoding G-protein-coupled receptor 65 (GPR65) has recently been reported to be a genetic risk facto...

    Authors: Irina V. Tcymbarevich, Jyrki J. Eloranta, Jean-Benoît Rossel, Nicole Obialo, Marianne Spalinger, Jesus Cosin-Roger, Silvia Lang, Gerd A. Kullak-Ublick, Carsten A. Wagner, Michael Scharl, Klaus Seuwen, Pedro A. Ruiz, Gerhard Rogler, Cheryl de Vallière and Benjamin Misselwitz

    Citation: BMC Gastroenterology 2019 19:2

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  14. Content type: Research article

    Intestinal alkaline phosphatase (IAP) plays important role in gut homeostasis. We aimed to evaluate the expression of endogenous IAP and to assess the clinical course according to the expression of endogenous ...

    Authors: Seon-Young Park, Ji-Young Kim, Su-Mi Lee, Jin Ook Chung, Ji-Ho Seo, SunMin Kim, Dong Hyun Kim, Chang-Hwan Park, Jae-Kyun Ju, Young-Eun Joo, Jae-Hyuk Lee, Hyun-Soo Kim, Sung-Kyu Choi and Jong-Sun Rew

    Citation: BMC Gastroenterology 2018 18:188

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  15. Content type: Research article

    Exclusive enteral nutrition (EEN) is as effective as corticosteroids in inducing remission in children with Crohn’s disease (CD). However, over 50% of these children relapse by 12 months of diagnosis. Thiopuri...

    Authors: Christina Ong, Poh Ting Lim, Veena Logarajah, Maria Janelle Liwanag, Bi Xia Ang, Yuqin Cher, Fang Kuan Chiou and Ajmal Kader

    Citation: BMC Gastroenterology 2018 18:185

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  16. Content type: Research article

    Blood loss from the gastrointestinal tract can be an acute and life-threatening event. For the treatment of gastrointestinal bleeding, it is important to accurately detect gastrointestinal bleeding and to loca...

    Authors: Yoichi Otomi, Hideki Otsuka, Kaori Terazawa, Moriaki Yamanaka, Yuki Obama, Maki Arase, Maki Otomo, Saho Irahara, Michiko Kubo, Naoto Uyama, Takashi Abe and Masafumi Harada

    Citation: BMC Gastroenterology 2018 18:183

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  18. Content type: Research article

    The adequacy of pre-procedure preparation is the principal determinant of the quality of colonoscopy in pediatric as in adult patients. There is a lack of consensus, among providers on a standard pre-procedure...

    Authors: Ashwath S. Kumar, Brooke L. Beutler and Thomas M. Attard

    Citation: BMC Gastroenterology 2018 18:170

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  19. Content type: Research article

    Alterations of the small-intestinal permeability (s-IP) might play an essential role in both diarrhoea-predominant IBS (D-IBS) and celiac disease (CD) patients. Our aims were to analyse in D-IBS patients the s...

    Authors: Michele Linsalata, Giuseppe Riezzo, Benedetta D’Attoma, Caterina Clemente, Antonella Orlando and Francesco Russo

    Citation: BMC Gastroenterology 2018 18:167

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  20. Content type: Research article

    Clinical severity and intestinal lesions of Crohn’s disease (CD) usually progress over time and require a step up adjustment of the therapy either to prevent or to treat complications. The aim of the study was...

    Authors: Nadia Pallotta, Giuseppina Vincoli, Patrizio Pezzotti, Maurizio Giovannone, Alessandro Gigliozzi, Danilo Badiali, Piero Vernia and Enrico Stefano Corazziari

    Citation: BMC Gastroenterology 2018 18:164

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  21. Content type: Case report

    The diagnosis of Coeliac disease (CD) requires a combination of sign/symptoms, positivity of specific antibodies and duodenal histological evidence of villous atrophy. Duodenal villous atrophy, despite represe...

    Authors: Vito Domenico Corleto, Vincenza Patrizia Di Marino, Gloria Galli, Giulio Antonelli, Chiara Coluccio, Arcangelo Di Cerbo, Stefania Uccini and Bruno Annibale

    Citation: BMC Gastroenterology 2018 18:162

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  24. Content type: Research article

    Gastrointestinal complications are the main cause of death in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Available treatments often restore biochemical homeostasis, but fail t...

    Authors: Rana Yadak, Max V. Boot, Niek P. van Til, Dominique Cazals-Hatem, Armin Finkenstedt, Elly Bogaerts, Irenaeus F. de Coo and Marianna Bugiani

    Citation: BMC Gastroenterology 2018 18:149

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  25. Content type: Research article

    Vedolizumab is safe and effective in adult patients with Crohn’s disease (CD) and ulcerative colitis (UC); however, data in children with inflammatory bowel disease (IBD) are scarce. Therefore, we evaluated ve...

    Authors: Anna-Maria Schneider, Daniel Weghuber, Benjamin Hetzer, Andreas Entenmann, Thomas Müller, Georg Zimmermann, Sebastian Schütz, Wolf-Dietrich Huber and Judith Pichler

    Citation: BMC Gastroenterology 2018 18:140

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  26. Content type: Case report

    The use of immune-checkpoint inhibitors in cancer treatment has become increasingly common, resulting in an increase in the incidence of related side effects. Diarrhoea and colitis have been previously documen...

    Authors: Ryosuke Yamauchi, Toshihiro Araki, Keiichi Mitsuyama, Takaaki Tokito, Hidenobu Ishii, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Tetsuhiro Yoshimura, Osamu Tsuruta and Takuji Torimura

    Citation: BMC Gastroenterology 2018 18:135

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  27. Content type: Research article

    Alteration of the gut microbiota by repeated antibiotic treatment increases susceptibility to Clostridioides difficile infection. Faecal microbiota transplantation from donors with a normal microbiota effectively...

    Authors: Jillian R.-M. Brown, Burkhardt Flemer, Susan A. Joyce, Akbar Zulquernain, Donal Sheehan, Fergus Shanahan and Paul W. O’Toole

    Citation: BMC Gastroenterology 2018 18:131

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  28. Content type: Research article

    Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance o...

    Authors: Takahiro Shimoyama, Takayuki Yamamoto, Satoru Umegae and Koichi Matsumoto

    Citation: BMC Gastroenterology 2018 18:120

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  29. Content type: Research article

    Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle s...

    Authors: Shi-Cheng Zheng, Hui Gong, Yi-Ping Wang, Qiang Zhang, Li-Li Wang, Xue-Fen Liao, Dai-Wen He and Jing Wu

    Citation: BMC Gastroenterology 2018 18:119

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  30. Content type: Research article

    Graft-versus-host disease (GVHD) is a common complication of allo-hematopoietic stem cell transplantation (allo-HSCT). Endoscopic biopsy can provide a definitive diagnosis, but the optimal endoscopic approach ...

    Authors: Yuusaku Sugihara, Sakiko Hiraoka, Nobuharu Fujii, Shiho Takashima, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Kenji Kuwaki, Keita Harada, Takehiro Tanaka and Hiroyuki Okada

    Citation: BMC Gastroenterology 2018 18:111

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  31. Content type: Case report

    Pneumatosis cystoides intestinalis (PCI) is characterized by gas-filled cysts in the intestinal submucosa and subserosa. There are few reports of PCI occurring in duodenum and rectum. Here we demonstrated four...

    Authors: Yong juan Wang, Yu ming Wang, Yan min Zheng, Hui qing Jiang and Jie Zhang

    Citation: BMC Gastroenterology 2018 18:100

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  32. Content type: Research article

    A high rate of complete colon capsule endoscopy (CCE) investigations is required for a more widespread use of CCE. The objective of this study was to assess if coffee or chewing gum can increase excretion of t...

    Authors: Maria Magdalena Buijs, Morten Kobaek-Larsen, Lasse Kaalby and Gunnar Baatrup

    Citation: BMC Gastroenterology 2018 18:95

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  33. Content type: Research article

    Human rotavirus (HRV) is a major cause of viral gastroenteritis in infants; particularly in developing countries where malnutrition is prevalent. Malnutrition perturbs the infant gut microbiota leading to sub-...

    Authors: Anand Kumar, Anastasia N. Vlasova, Loic Deblais, Huang-Chi Huang, Asela Wijeratne, Sukumar Kandasamy, David D. Fischer, Stephanie N. Langel, Francine Chimelo Paim, Moyasar A. Alhamo, Lulu Shao, Linda J. Saif and Gireesh Rajashekara

    Citation: BMC Gastroenterology 2018 18:93

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  34. Content type: Case report

    Crohn’s Disease (CD) is typically characterized by abdominal symptoms, however, besides gastrointestinal symptoms, CD patients may suffer from extraintestinal manifestations which are far less common and medic...

    Authors: Arne Bokemeyer, Nicolas Tentrop, Peter J. Barth, Frank Lenze, Karin Hengst, Johannes Kleinheinz and Dominik Bettenworth

    Citation: BMC Gastroenterology 2018 18:88

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  35. Content type: Research article

    Endoscopic submucosal dissection (ESD) has been widely accepted for treating superficial esophageal squamous cell carcinoma (SESCC). The aim of this study was to evaluate the efficacy and safety of ESD for SES...

    Authors: Byeong Geun Song, Yang Won Min, Ra Ri Cha, Hyuk Lee, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee and Jae J. Kim

    Citation: BMC Gastroenterology 2018 18:80

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  36. Content type: Case report

    Adenocarcinomas or combined adeno-neuroendocrine carcinomas (MANEC) of small bowel usually have a dismal prognosis with limited systemic therapy options. This is the first description of a patient showing a ge...

    Authors: A. Quaas, D. Waldschmidt, H. Alakus, T. Zander, C. Heydt, T. Goeser, M. Daheim, P. Kasper, P. Plum, C. Bruns, A. Brunn, W. Roth, N. Hartmann, A. Bunck, M. Schmidt, H. Göbel…

    Citation: BMC Gastroenterology 2018 18:75

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  37. Content type: Research article

    Due to finite resources, the clinical decision to subject a patient to colonoscopy needs to be based on the evidence, regardless of its availability, affordability and safety. This study assessed the appropria...

    Authors: Yasara Samarakoon, Nalika Gunawardena, Aloka Pathirana and Sumudu Hewage

    Citation: BMC Gastroenterology 2018 18:72

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  38. Content type: Research article

    Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce the numbers of pathogenic bacteria and help alleviate...

    Authors: Shamsuddin M. Ishaque, S. M. Khosruzzaman, Dewan Saifuddin Ahmed and Mukesh Prasad Sah

    Citation: BMC Gastroenterology 2018 18:71

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  39. Content type: Research article

    Celiac disease (CD) is a common autoimmune disease in Syria which manifesting with inflammation of the small intestine and with various extra intestinal symptoms. The disease is associated with human HLA-DQ ge...

    Authors: Hossam Murad, Batoul Jazairi, Issam Khansaa, Doaa Olabi and Lina Khouri

    Citation: BMC Gastroenterology 2018 18:70

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  40. Content type: Research article

    It is not clear why some patients with coeliac disease (CD) present with severe symptoms and small intestinal mucosal damages while others present with milder symptoms and no frank enteropathy. There is no stu...

    Authors: Mohammad Rostami-Nejad, Seyed Hossein Hejazi, Amado Salvador Peña, Hamid Asadzadeh-Aghdaei, Kamran Rostami, Umberto Volta and Mohammad Reza Zali

    Citation: BMC Gastroenterology 2018 18:66

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  41. Content type: Case report

    A relationship between IgA nephropathy (IgAN) and celiac disease (CD) has been reported. We show the pathogenetic link for the first time.

    Authors: Stefano Costa, Giovanni Currò, Salvatore Pellegrino, Maria Cristina Lucanto, Giovanni Tuccari, Antonio Ieni, Giuseppina Visalli, Giuseppe Magazzù and Domenico Santoro

    Citation: BMC Gastroenterology 2018 18:64

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  43. Content type: Research article

    Rett syndrome (RTT) is a neurological disorder mainly caused by mutations in MeCP2 gene. It has been shown that MeCP2 impairments can lead to cytokine dysregulation due to MeCP2 regulatory role in T-helper and T-...

    Authors: Francesco Strati, Antonio Calabrò, Claudio Donati, Claudio De Felice, Joussef Hayek, Olivier Jousson, Silvia Leoncini, Daniela Renzi, Lisa Rizzetto, Carlotta De Filippo and Duccio Cavalieri

    Citation: BMC Gastroenterology 2018 18:57

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  44. Content type: Research article

    Several pull-through procedures have been described for Hirschsprung disease (HSCR) with varying functional outcomes. The voluntary bowel movement (VBM) and the absence of soiling or constipation after pull-th...

    Authors: Amira Widyasari, Winona Alda Pravitasari, Andi Dwihantoro and Gunadi

    Citation: BMC Gastroenterology 2018 18:56

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    The Correction to this article has been published in BMC Gastroenterology 2018 18:110

  45. Content type: Research article

    Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with...

    Authors: Richelle J. F. Felt-Bersma, Maarten S. Vlietstra, Paul F. Vollebregt, Ingrid J. M. Han-Geurts, Vera Rempe-Sorm, Grietje J. H. Vander Mijnsbrugge and Charlotte B. H. Molenaar

    Citation: BMC Gastroenterology 2018 18:44

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  47. Content type: Research article

    The primary purpose of this study was to compare Rome III and IV evaluation criteria for irritable bowel syndrome (IBS), functional dyspepsia (FD), and an overlap syndrome consisting of both IBS and FD by asse...

    Authors: Trent Edwards, Craig Friesen and Jennifer V. Schurman

    Citation: BMC Gastroenterology 2018 18:41

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  49. Content type: Research article

    The primary function of the intestines is the absorption of water and nutrients. Although our knowledge about these processes on the cellular level is extensive, a number of important intracellular elements re...

    Authors: Satu Oltedal, Ivar Skaland, Jodi Maple-Grødem, Kjersti Tjensvoll, Emiel A. M. Janssen, Bjørnar Gilje, Rune Smaaland, Reino Heikkilä and Oddmund Nordgård

    Citation: BMC Gastroenterology 2018 18:26

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