Skip to main content

Gastroesophageal disorders

This section concerns all clinical and basic science aspects of gastroesophageal disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

Page 4 of 8

  1. We present the first description of en bloc endoscopic submucosal dissection (ESD) for total circumferential Barrett’s adenocarcinoma, predominantly of the long-segment Barrett’s esophagus (LSBE), with a 2-year f...

    Authors: Miki Kaneko, Akira Mitoro, Motoyuki Yoshida, Masayoshi Sawai, Yasushi Okura, Masanori Furukawa, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Hideto Kawaratani, Mitsuteru Kitade, Kousuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Shinya Sato…

    Citation: BMC Gastroenterology 2018 18:16

    Content type: Case report

    Published on:

  2. Slingshot homolog-1 (SSH1) plays an important role in pathological processes, including in the occurrence and development of tumours. The purpose of this study was to determine whether SSH1 is a key biomarker ...

    Authors: Yusufu Maimaiti, Maimaitiaili Maimaitiming, Yiliang Li, Saifuding Aibibula, Azatijiang Ainiwaer, Aikebaier Aili, Zhenzhu Sun and Kelimu Abudureyimu

    Citation: BMC Gastroenterology 2018 18:12

    Content type: Research article

    Published on:

  3. Gastroesophageal reflux disease (GERD) is a factor that has a significant negative impact on the quality of life (QoL). Vertebral fractures and/or spinal malalignment may influence the frequency of GERD. Howev...

    Authors: Tetsuro Ohba, Shigeto Ebata, Kensuke Koyama and Hirotaka Haro

    Citation: BMC Gastroenterology 2018 18:8

    Content type: Research article

    Published on:

  4. Upper gastrointestinal bleeding (UGIB) is a common gastrointestinal emergency, which is potentially fatal. Proper management of UGIB requires risk-stratification of patients which can guide the type and aggres...

    Authors: Sibtain M. Moledina and Ewaldo Komba

    Citation: BMC Gastroenterology 2017 17:165

    Content type: Research article

    Published on:

  5. Increasing attention is focused on the relationship of inflammation biomarkers with malignant tumors. The purpose of the present study was to detect whether the preoperative the red distribution width (RDW) an...

    Authors: Shiqing Cheng, Fuyan Han, Yong Wang, Yanqiu Xu, Teng Qu, Ying Ju and Zhiming Lu

    Citation: BMC Gastroenterology 2017 17:163

    Content type: Research article

    Published on:

  6. Risk scoring systems are used to evaluate patients with upper gastrointestinal bleeding (UGIB). We compared Glasgow-Blatchford score (GBS), modified GBS (mGBS), and Pre-endoscopy Rockall score (Pre-E RS) for i...

    Authors: Il-Gyu Ko, Sung-Eun Kim, Bok Soon Chang, Min Seob Kwak, Jin Young Yoon, Jae Myung Cha, Hyun Phil Shin, Joung Il Lee, Sang Hyun Kim, Jin Hee Han and Jung Won Jeon

    Citation: BMC Gastroenterology 2017 17:159

    Content type: Research article

    Published on:

  7. Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left unt...

    Authors: Flaminia Purchiaroni, Takeshi Nakajima, Taku Sakamoto, Seiichiro Abe and Yutaka Saito

    Citation: BMC Gastroenterology 2017 17:152

    Content type: Case report

    Published on:

  8. Esophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy ...

    Authors: Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Homma Taku, Moritaka Ohhara, Toshirou Takimoto and Yoshiaki Tanaka

    Citation: BMC Gastroenterology 2017 17:151

    Content type: Case report

    Published on:

  9. Blue laser imaging (BLI) and linked color imaging (LCI) are the color enhancement features of the LASEREO endoscopic system, which provide a narrow band light observation function and expansion and reduction o...

    Authors: Yoshikazu Yoshifuku, Yoji Sanomura, Shiro Oka, Mio Kurihara, Takeshi Mizumoto, Tomohiro Miwata, Yuji Urabe, Toru Hiyama, Shinji Tanaka and Kazuaki Chayama

    Citation: BMC Gastroenterology 2017 17:150

    Content type: Research article

    Published on:

  10. Gastric cancer is a frequent malignant tumor worldwide and its early detection is crucial for curing the disease and enhancing patients’ survival rate. This study aimed to assess whether the multi-disciplinary...

    Authors: Lianjun Di, Huichao Wu, Rong Zhu, Youfeng Li, Xinglong Wu, Rui Xie, Hongping Li, Haibo Wang, Hua Zhang, Hong Xiao, Hui Chen, Hong Zhen, Kui Zhao, Xuefeng Yang, Ming Xie and Bigung Tuo

    Citation: BMC Gastroenterology 2017 17:147

    Content type: Research article

    Published on:

  11. Although Helicobacter-induced gastric inflammation is the major predisposing factor for gastric carcinogenesis, the precise mechanism by which chronic gastritis causes gastric cancer remains unclear. Intestinal a...

    Authors: Wataru Shibata, Soichiro Sue, Sachiko Tsumura, Yasuaki Ishii, Takeshi Sato, Eri Kameta, Makoto Sugimori, Hiroaki Yamada, Hiroaki Kaneko, Tomohiko Sasaki, Tomohiro Ishii, Toshihide Tamura, Masaaki Kondo and Shin Maeda

    Citation: BMC Gastroenterology 2017 17:145

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Gastroenterology 2018 18:4

  12. The prognosis of a gastrointestinal stromal tumor (GIST) is influenced by its anatomic site; however, few studies on the prognosis of gastric GISTs have been reported. The aims of this study were to evaluate l...

    Authors: Chul Hong Park, Gwang Ha Kim, Bong Eun Lee, Geun Am Song, Do Youn Park, Kyung Un Choi, Dae Hwan Kim and Tae Yong Jeon

    Citation: BMC Gastroenterology 2017 17:141

    Content type: Research article

    Published on:

  13. Gastro-esophageal reflux disease (GERD) is suggested to be associated with some socio-demographic and lifestyle factors. Although the roles of some factors such as obesity are well documented, evidence on the ...

    Authors: Omid Eslami, Mansour Shahraki, Ali Bahari and Touran Shahraki

    Citation: BMC Gastroenterology 2017 17:132

    Content type: Research article

    Published on:

  14. The present study was performed to compare the safety of sedation during endoscopic submucosal dissection (ESD) in the endoscopy room versus operation room.

    Authors: Daisuke Yamaguchi, Naoko Yamaguchi, Yuki Takeuchi, Takahiro Yukimoto, Kei Ikeda, Kosuke Matsumoto, Rikako Kinoshita, Saori Kamachi, Kyosuke Sugiyama, Tomohito Morisaki, Keisuke Ario, Hisako Yoshida, Ryo Katsuki, Seiji Tsunada and Kazuma Fujimoto

    Citation: BMC Gastroenterology 2017 17:127

    Content type: Research article

    Published on:

  15. Functional dyspepsia (FD) is a gastrointestinal disorder characterized by recurrent and diverse symptoms and pathophysiology that remains unexplained following routine clinical investigation. Enzynorm®f is a phar...

    Authors: Kristin Forssmann, Larissa Meier, Bernhard Uehleke, Cornelia Breuer and Rainer Stange

    Citation: BMC Gastroenterology 2017 17:123

    Content type: Research article

    Published on:

  16. The anatomy of esophagogastric junction (EGJ) serves as the anti-reflux barrier. The gastroesophageal flap valve (GEFV) is a component of EGJ. The aim of the current study was to assess its correlation with th...

    Authors: Chenxi Xie, Yuwen Li, Ning Zhang, Lishou Xiong, Minhu Chen and Yinglian Xiao

    Citation: BMC Gastroenterology 2017 17:118

    Content type: Research article

    Published on:

  17. Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms. No longitudinal studies of reflux-associated erosive...

    Authors: Clive H. Wilder-Smith, Andrea Materna, Lukas Martig and Adrian Lussi

    Citation: BMC Gastroenterology 2017 17:113

    Content type: Research article

    Published on:

  18. Globus pharyngeus is common and has a low cure rate. Its etiology is complex and reported to be associated with laryngopharyngeal reflux (LPR). However, some patients with globus do not exhibit any reflux symp...

    Authors: Heyan Ding, Zhijun Duan, Dong Yang, Zhifeng Zhang, Lixia Wang, Xiaoyu Sun, Yiwen Yao, Xue Lin, Hang Yang, Shan Wang and Jiande D. Z. Chen

    Citation: BMC Gastroenterology 2017 17:109

    Content type: Research article

    Published on:

  19. None of current diagnostic methods has been proven to be a reliable tool for gastro-esophageal reflux disease (GERD). Pepsin in saliva has been proposed as a promising diagnostic biomarker for gastro-esophagea...

    Authors: Xing Du, Feng Wang, Zhiwei Hu, Jimin Wu, Zhonggao Wang, Chao Yan, Chao Zhang and Juan Tang

    Citation: BMC Gastroenterology 2017 17:107

    Content type: Research article

    Published on:

  20. “Lichenoid esophagitis” is a descriptive term for a lichenoid pattern of inflammation in the esophagus for which a precise histologic diagnosis cannot be established. The differential diagnosis includes lichen...

    Authors: Andrew Mitchell and Tony Petrella

    Citation: BMC Gastroenterology 2017 17:95

    Content type: Case report

    Published on:

  21. We report a unique case of a superficial esophageal cancer arising in a single diverticulum, diagnosed with magnifying image-enhanced endoscopy and then successfully treated by endoscopic submucosal dissection...

    Authors: Kuangi Fu, Peng Jin, Yuqi He, Masanori Suzuki and Jianqiu Sheng

    Citation: BMC Gastroenterology 2017 17:94

    Content type: Case report

    Published on:

  22. Occurrence of metastatic cancer to the stomach is rare, particularly in patients with prostate cancer. Gastric metastasis generally presents as a solitary and submucosal lesion with a central depression.

    Authors: Chiaki Inagaki, Takuto Suzuki, Yoshiyasu Kitagawa, Taro Hara and Taketo Yamaguchi

    Citation: BMC Gastroenterology 2017 17:93

    Content type: Case report

    Published on:

  23. Dental erosion (DE), one of oral hard tissue diseases, is one of the extraoesophageal symptoms defined as the Montreal Definition and Classification of gastroesophageal reflux disease (GERD). However, no study...

    Authors: Masaaki Watanabe, Eiji Nakatani, Hiroo Yoshikawa, Takahiro Kanno, Yoshiki Nariai, Aya Yoshino, Michael Vieth, Yoshikazu Kinoshita and Joji Sekine

    Citation: BMC Gastroenterology 2017 17:92

    Content type: Research article

    Published on:

  24. Dieulafoy’s lesion (DL) is one of the rare causes of upper gastrointestional bleeding. This disease is characterized by small sub-mucosal arteriole that eroded the stomach mucosa and cause severe upper GI blee...

    Authors: Chen Si, Zhu Xiuli, Xie Li, Jia Yong, Zhou Ying and Zhang Kaiguang

    Citation: BMC Gastroenterology 2017 17:89

    Content type: Case report

    Published on:

  25. The aim of this study is to assess the validity of the measurement of pepsinogen as a screening test for chronic atrophic gastritis (AG) in health check-up populations in China.

    Authors: Yuling Tong, Yulian Wu, Zhenya Song, Yingying Yu and Xinyan Yu

    Citation: BMC Gastroenterology 2017 17:88

    Content type: Research article

    Published on:

  26. The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to 14%. Regarding cases with adenocarcinoma within IP,...

    Authors: Ulrich Peitz, Michael Vieth, Matthias Evert, Jovana Arand, Albert Roessner and Peter Malfertheiner

    Citation: BMC Gastroenterology 2017 17:87

    Content type: Research article

    Published on:

  27. Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) are characterized by an increase of proliferation and a reduction of apoptosis in epithelial cells. The epithelial cell k...

    Authors: R. Rosania, M. Varbanova, T. Wex, C. Langner, J. Bornschein, F. Giorgio, E. Ierardi and P. Malfertheiner

    Citation: BMC Gastroenterology 2017 17:84

    Content type: Research article

    Published on:

  28. Controversies persist regarding the effect of prokinetics for the treatment of functional dyspepsia (FD). This study aimed to assess the comparative efficacy of prokinetic agents for the treatment of FD.

    Authors: Young Joo Yang, Chang Seok Bang, Gwang Ho Baik, Tae Young Park, Suk Pyo Shin, Ki Tae Suk and Dong Joon Kim

    Citation: BMC Gastroenterology 2017 17:83

    Content type: Research article

    Published on:

  29. Obesity is a growing epidemic around the world, and obese patients are generally regarded as high risk for surgery compared with normal weight patients. The purpose of this study was to evaluate the influence ...

    Authors: Ke Chen, Yu Pan, Shu-ting Zhai, Jia-qin Cai, Qi-long Chen, Ding-wei Chen, Yi-ping Zhu, Yu Zhang, Ya-ping Zhang, Hendi Maher and Xian-fa Wang

    Citation: BMC Gastroenterology 2017 17:78

    Content type: Research article

    Published on:

  30. By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflu...

    Authors: Feng Gao, Yan Gao, Xue Chen, Jie Qian and Jie Zhang

    Citation: BMC Gastroenterology 2017 17:67

    Content type: Research article

    Published on:

  31. FBXW7, a component of the Skp-Cullin1-F-box, mediates target protein recognition. It is a tumor suppressor gene that plays a role in the regulation of cell cycle exit and reentry via c-Myc, c-Jun and Notch deg...

    Authors: Mao-Ran Li, Chun-Chao Zhu, Tian-Long Ling, Ye-Qian Zhang, Jia Xu, En-Hao Zhao and Gang Zhao

    Citation: BMC Gastroenterology 2017 17:60

    Content type: Research article

    Published on:

  32. Adding a second endoscopic therapy to epinephrine injection might improve hemostatic efficacy in patients with high-risk bleeding ulcers but the optimum modality remains unknown. We aimed to estimate the compa...

    Authors: Keda Shi, Zeren Shen, Guiqi Zhu, Fansheng Meng, Mengli Gu and Feng Ji

    Citation: BMC Gastroenterology 2017 17:55

    Content type: Research article

    Published on:

  33. Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of th...

    Authors: Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto, Shiro Nakamura, Soji Omuro, Mamoru Watanabe and Toshifumi Hibi

    Citation: BMC Gastroenterology 2017 17:47

    Content type: Research article

    Published on:

  34. To assess the associations of biomarkers of intestinal barrier function and other clinical variables with acute gastrointestinal injury (AGI) grade, and of these clinical variables with mortality in critically...

    Authors: Hongxiang Li, Ying Chen, Feifei Huo, Yushan Wang and Dong Zhang

    Citation: BMC Gastroenterology 2017 17:45

    Content type: Research article

    Published on:

  35. Neoadjuvant chemotherapy has been increasingly practiced on gastric cancer (GC), and histological evaluation to predict outcome is urgent in clinical practice. There are five classic tumor regression grading (...

    Authors: Yuelu Zhu, Yongkun Sun, Shangying Hu, Yong Jiang, Jiangying Yue, Xuemin Xue, Lin Yang and Liyan Xue

    Citation: BMC Gastroenterology 2017 17:41

    Content type: Research article

    Published on:

  36. In type 1 multiple endocrine neoplasia (MEN1), esophageal diseases association with excessive gastrin secretion in Zollinger-Ellison syndrome (ZES) sometimes develop. Here, we reported a case of MEN1/ZES, who ...

    Authors: Hiroyuki Matsubayashi, Noboru Kawata, Naomi Kakushima, Masaki Tanaka, Kohei Takizawa, Yoshimi Kiyozumi, Yasue Horiuchi, Keiko Sasaki, Teiichi Sugiura, Katsuhiko Uesaka and Hiroyuki Ono

    Citation: BMC Gastroenterology 2017 17:37

    Content type: Case report

    Published on:

  37. Claudins are a family of integral membrane proteins and are components of tight junctions (TJs). Many TJ proteins are known to tighten the cell structure and maintain a barrier. Claudin-2 forms gated paracellu...

    Authors: Sohaib Abu-Farsakh, Tongtong Wu, Amy Lalonde, Jun Sun and Zhongren Zhou

    Citation: BMC Gastroenterology 2017 17:33

    Content type: Research article

    Published on:

  38. Helicobacter pylori eradication rates in Portugal are declining, due to increased resistance of this bacterium to antimicrobial agents, especially Clarithromycin. Quadruple Levofloxaci...

    Authors: Diogo Branquinho, Nuno Almeida, Carlos Gregório, José Eduardo Pina Cabral, Adriano Casela, Maria Manuel Donato and Luís Tomé

    Citation: BMC Gastroenterology 2017 17:31

    Content type: Research article

    Published on:

  39. Uridine (Urd), which has been reported as a major component of RNA, plays an important role in various biological process including neuroprotection, biochemical modulation and glycolysis, although its role in ...

    Authors: Ji Eun Kim, Jun Go, Ji Eun Sung, Hyun Ah Lee, Woo Bin Yun, Jin Tae Hong and Dae Youn Hwang

    Citation: BMC Gastroenterology 2017 17:21

    Content type: Research article

    Published on:

  40. The eradication rate of Helicobacter pylori (H. pylori) with triple therapy which was considered as standard first-line treatment has decreased to 70–85%. The aim of this study is to compare 7-day triple therapy ...

    Authors: Ji Young Chang, Ki-Nam Shim, Chung Hyun Tae, Ko Eun Lee, Jihyun Lee, Kang Hoon Lee, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung and Sung-Ae Jung

    Citation: BMC Gastroenterology 2017 17:16

    Content type: Research article

    Published on:

  41. The detectable rate of minimal gastric GISTs has continuously increased. While the surveillance and management of GIST <2 cm have been deemed controversial or lack evidence-based approaches.  The aim of the cu...

    Authors: Zhidong Gao, Chao Wang, Qian Xue, Jingtong Wang, Zhanlong Shen, Kewei Jiang, Kai Shen, Bin Liang, Xiaodong Yang, Qiwei Xie, Shan Wang and Yingjiang Ye

    Citation: BMC Gastroenterology 2017 17:8

    Content type: Research article

    Published on:

  42. Whether gastrointestinal motor and sensory function is primary cause or secondary effect of abnormal body weight is uncertain. Moreover, studies relating continuous postprandial sensations of satiation to meas...

    Authors: Sena Bluemel, Dieter Menne, Gabriella Milos, Oliver Goetze, Michael Fried, Werner Schwizer, Mark Fox and Andreas Steingoetter

    Citation: BMC Gastroenterology 2017 17:4

    Content type: Research article

    Published on:

  43. Individualized therapeutic regimen is a recently intensively pursued approach for targeting diseases, in which the search for biomarkers was considered the first and most important. Thus, the goal of this stud...

    Authors: Yongkuan Cao, Guohu Zhang, Peihong Wang, Jun Zhou, Wei Gan, Yaning Song, Ling Huang, Ya Zhang, Guode Luo, Jiaqing Gong and Lin Zhang

    Citation: BMC Gastroenterology 2017 17:2

    Content type: Research article

    Published on:

  44. Gastric epithelial hyper-proliferation was reported in patients with Helicobacter pylori (H. pylori)–infected gastric mucosa with intestinal metaplasia (IM) changes. In patients with gastric ulcer (GU) and IM, th...

    Authors: Li-Wei Chen, Liang-Che Chang, Chung-Ching Hua, Bor-Jen Hsieh, Shuo-Wei Chen and Rong-Nan Chien

    Citation: BMC Gastroenterology 2017 17:1

    Content type: Research article

    Published on:

  45. Body mass index (BMI), resting energy expenditure (REE) and fasting blood glucose (FBG) are major preoperative assessments of patients’ nutrition and metabolic state. The relations and effects of these indices...

    Authors: Ning Wu, Yongjun Zhu, Dhruba Kadel, Liewen Pang, Gang Chen and Zhiming Chen

    Citation: BMC Gastroenterology 2016 16:142

    Content type: Research article

    Published on:

  46. Proximal or ‘downhill’ esophageal varices are a rare cause of upper gastrointestinal hemorrhage. Unlike the much more common distal esophageal varices, which are most commonly a result of portal hypertension, ...

    Authors: Michael Loudin, Sharon Anderson and Barry Schlansky

    Citation: BMC Gastroenterology 2016 16:134

    Content type: Case report

    Published on:

  47. Gastric foveolar hyperplastic polyps (GFHPs) are common findings in clinical practice. GFHPs commonly arise in a background of chronic atrophic gastritis, including autoimmune gastritis (type A gastritis), and...

    Authors: Kenichi Yamanaka, Hiroyuki Miyatani, Yukio Yoshida, Takehiro Ishii, Shinichi Asabe, Osamu Takada, Mitsuhiro Nokubi and Hirosato Mashima

    Citation: BMC Gastroenterology 2016 16:130

    Content type: Case report

    Published on:

  48. Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5–2 episodes/year/person and an incidence of 5–100 episodes/1000/week according to seasons and age. There i...

    Authors: Francesca Uberti, Claudio Bardelli, Vera Morsanuto, Sabrina Ghirlanda and Claudio Molinari

    Citation: BMC Gastroenterology 2016 16:127

    Content type: Research article

    Published on:

  49. The rate for upper gastrointestinal (UGI) cancers, and especially the rate for gastric cancer, varies from country to country and from region to region within country. In Turkey, the incidence of gastric cance...

    Authors: Albayrak Fatih, Ozturk Yasin, Dursun Hakan and Albayrak Yavuz

    Citation: BMC Gastroenterology 2016 16:120

    Content type: Research article

    Published on:

  50. Helicobacter pylori (H. pylori) infection and eradication therapy have been known to influence gastric ghrelin and leptin secretion, which may lead to weight gain. However, the exact relationship between plasma g...

    Authors: Chika Kasai, Kazushi Sugimoto, Isao Moritani, Junichiro Tanaka, Yumi Oya, Hidekazu Inoue, Masahiko Tameda, Katsuya Shiraki, Masaaki Ito, Yoshiyuki Takei and Kojiro Takase

    Citation: BMC Gastroenterology 2016 16:119

    Content type: Research article

    Published on:

2019 Journal Metrics