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BMC Gastroenterology

Gastroesophageal disorders

Section edited by Yeong Yeh Lee and Jan Bornschein

This section concerns all clinical and basic science aspects of gastroesophageal disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

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  1. Content type: Research article

    Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms. No longitudinal studies of reflux-associated erosive...

    Authors: Clive H. Wilder-Smith, Andrea Materna, Lukas Martig and Adrian Lussi

    Citation: BMC Gastroenterology 2017 17:113

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  2. Content type: Research article

    Globus pharyngeus is common and has a low cure rate. Its etiology is complex and reported to be associated with laryngopharyngeal reflux (LPR). However, some patients with globus do not exhibit any reflux symp...

    Authors: Heyan Ding, Zhijun Duan, Dong Yang, Zhifeng Zhang, Lixia Wang, Xiaoyu Sun, Yiwen Yao, Xue Lin, Hang Yang, Shan Wang and Jiande D. Z. Chen

    Citation: BMC Gastroenterology 2017 17:109

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  3. Content type: Research article

    None of current diagnostic methods has been proven to be a reliable tool for gastro-esophageal reflux disease (GERD). Pepsin in saliva has been proposed as a promising diagnostic biomarker for gastro-esophagea...

    Authors: Xing Du, Feng Wang, Zhiwei Hu, Jimin Wu, Zhonggao Wang, Chao Yan, Chao Zhang and Juan Tang

    Citation: BMC Gastroenterology 2017 17:107

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  4. Content type: Case report

    “Lichenoid esophagitis” is a descriptive term for a lichenoid pattern of inflammation in the esophagus for which a precise histologic diagnosis cannot be established. The differential diagnosis includes lichen...

    Authors: Andrew Mitchell and Tony Petrella

    Citation: BMC Gastroenterology 2017 17:95

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  5. Content type: Research article

    Dental erosion (DE), one of oral hard tissue diseases, is one of the extraoesophageal symptoms defined as the Montreal Definition and Classification of gastroesophageal reflux disease (GERD). However, no study...

    Authors: Masaaki Watanabe, Eiji Nakatani, Hiroo Yoshikawa, Takahiro Kanno, Yoshiki Nariai, Aya Yoshino, Michael Vieth, Yoshikazu Kinoshita and Joji Sekine

    Citation: BMC Gastroenterology 2017 17:92

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  6. Content type: Case report

    Occurrence of metastatic cancer to the stomach is rare, particularly in patients with prostate cancer. Gastric metastasis generally presents as a solitary and submucosal lesion with a central depression.

    Authors: Chiaki Inagaki, Takuto Suzuki, Yoshiyasu Kitagawa, Taro Hara and Taketo Yamaguchi

    Citation: BMC Gastroenterology 2017 17:93

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  7. Content type: Case report

    We report a unique case of a superficial esophageal cancer arising in a single diverticulum, diagnosed with magnifying image-enhanced endoscopy and then successfully treated by endoscopic submucosal dissection...

    Authors: Kuangi Fu, Peng Jin, Yuqi He, Masanori Suzuki and Jianqiu Sheng

    Citation: BMC Gastroenterology 2017 17:94

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  8. Content type: Case report

    Dieulafoy’s lesion (DL) is one of the rare causes of upper gastrointestional bleeding. This disease is characterized by small sub-mucosal arteriole that eroded the stomach mucosa and cause severe upper GI blee...

    Authors: Chen Si, Zhu Xiuli, Xie Li, Jia Yong, Zhou Ying and Zhang Kaiguang

    Citation: BMC Gastroenterology 2017 17:89

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  9. Content type: Research article

    The aim of this study is to assess the validity of the measurement of pepsinogen as a screening test for chronic atrophic gastritis (AG) in health check-up populations in China.

    Authors: Yuling Tong, Yulian Wu, Zhenya Song, Yingying Yu and Xinyan Yu

    Citation: BMC Gastroenterology 2017 17:88

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  10. Content type: Research article

    The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to 14%. Regarding cases with adenocarcinoma within IP,...

    Authors: Ulrich Peitz, Michael Vieth, Matthias Evert, Jovana Arand, Albert Roessner and Peter Malfertheiner

    Citation: BMC Gastroenterology 2017 17:87

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  11. Content type: Research article

    Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) are characterized by an increase of proliferation and a reduction of apoptosis in epithelial cells. The epithelial cell k...

    Authors: R. Rosania, M. Varbanova, T. Wex, C. Langner, J. Bornschein, F. Giorgio, E. Ierardi and P. Malfertheiner

    Citation: BMC Gastroenterology 2017 17:84

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  12. Content type: Research article

    Controversies persist regarding the effect of prokinetics for the treatment of functional dyspepsia (FD). This study aimed to assess the comparative efficacy of prokinetic agents for the treatment of FD.

    Authors: Young Joo Yang, Chang Seok Bang, Gwang Ho Baik, Tae Young Park, Suk Pyo Shin, Ki Tae Suk and Dong Joon Kim

    Citation: BMC Gastroenterology 2017 17:83

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  13. Content type: Research article

    Obesity is a growing epidemic around the world, and obese patients are generally regarded as high risk for surgery compared with normal weight patients. The purpose of this study was to evaluate the influence ...

    Authors: Ke Chen, Yu Pan, Shu-ting Zhai, Jia-qin Cai, Qi-long Chen, Ding-wei Chen, Yi-ping Zhu, Yu Zhang, Ya-ping Zhang, Hendi Maher and Xian-fa Wang

    Citation: BMC Gastroenterology 2017 17:78

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  14. Content type: Research article

    By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflu...

    Authors: Feng Gao, Yan Gao, Xue Chen, Jie Qian and Jie Zhang

    Citation: BMC Gastroenterology 2017 17:67

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  15. Content type: Research article

    FBXW7, a component of the Skp-Cullin1-F-box, mediates target protein recognition. It is a tumor suppressor gene that plays a role in the regulation of cell cycle exit and reentry via c-Myc, c-Jun and Notch deg...

    Authors: Mao-Ran Li, Chun-Chao Zhu, Tian-Long Ling, Ye-Qian Zhang, Jia Xu, En-Hao Zhao and Gang Zhao

    Citation: BMC Gastroenterology 2017 17:60

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  16. Content type: Research article

    Adding a second endoscopic therapy to epinephrine injection might improve hemostatic efficacy in patients with high-risk bleeding ulcers but the optimum modality remains unknown. We aimed to estimate the compa...

    Authors: Keda Shi, Zeren Shen, Guiqi Zhu, Fansheng Meng, Mengli Gu and Feng Ji

    Citation: BMC Gastroenterology 2017 17:55

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  17. Content type: Research article

    Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of th...

    Authors: Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto, Shiro Nakamura, Soji Omuro, Mamoru Watanabe and Toshifumi Hibi

    Citation: BMC Gastroenterology 2017 17:47

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  18. Content type: Research article

    To assess the associations of biomarkers of intestinal barrier function and other clinical variables with acute gastrointestinal injury (AGI) grade, and of these clinical variables with mortality in critically...

    Authors: Hongxiang Li, Ying Chen, Feifei Huo, Yushan Wang and Dong Zhang

    Citation: BMC Gastroenterology 2017 17:45

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  19. Content type: Research article

    Neoadjuvant chemotherapy has been increasingly practiced on gastric cancer (GC), and histological evaluation to predict outcome is urgent in clinical practice. There are five classic tumor regression grading (...

    Authors: Yuelu Zhu, Yongkun Sun, Shangying Hu, Yong Jiang, Jiangying Yue, Xuemin Xue, Lin Yang and Liyan Xue

    Citation: BMC Gastroenterology 2017 17:41

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  20. Content type: Case report

    In type 1 multiple endocrine neoplasia (MEN1), esophageal diseases association with excessive gastrin secretion in Zollinger-Ellison syndrome (ZES) sometimes develop. Here, we reported a case of MEN1/ZES, who ...

    Authors: Hiroyuki Matsubayashi, Noboru Kawata, Naomi Kakushima, Masaki Tanaka, Kohei Takizawa, Yoshimi Kiyozumi, Yasue Horiuchi, Keiko Sasaki, Teiichi Sugiura, Katsuhiko Uesaka and Hiroyuki Ono

    Citation: BMC Gastroenterology 2017 17:37

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