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Epidemiology of gastroenterological disorders

This section aims to publish research on the prevalence and the environmental, behavioral, dietary and occupational correlates of gastrointestinal and hepatobiliary disorders

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  1. Chronic lead poisoning (CLP) is a rare cause of abdominal pain and is common in young children, in whom the incidence is higher than it is in adults. As the symptoms of CLP are nonspecific, misdiagnoses or mis...

    Authors: Yuan Yang, Shujun Li, Hong Wang, Morong Liu, Biguang Tuo, Huichao Wu, Shili Deng and Xuemei Liu

    Citation: BMC Gastroenterology 2020 20:335

    Content type: Case report

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  2. Disaccharides such as lactose and sucrose are sugars commonly found in human diet. They are broken down by mucosal disaccharidases in the duodenum. Previous small studies found no associations between gastroin...

    Authors: Paul Wasuwanich, Hassan Choudry, Thammasin Ingviya, Ann O. Scheimann, Karla J. AuYeung, Christine Karwowski, Susan Billet, Buford L. Nichols and Wikrom Karnsakul

    Citation: BMC Gastroenterology 2020 20:331

    Content type: Research article

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  3. The purpose of this study was to identify common gastrointestinal (GI) symptom groups using the Patient-Reported Outcomes Measurement Information System - GI symptom scales (PROMIS-GI) within a large sample of...

    Authors: Helize Vivier, Emily J. Ross and Jeffrey E. Cassisi

    Citation: BMC Gastroenterology 2020 20:326

    Content type: Research article

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  4. Inflammatory bowel diseases are classic polygenic disorders, with genetic loads that reflect immunopathological processes in response to the intestinal microbiota. Herein we performed the multiomics analysis b...

    Authors: Filip Ambrozkiewicz, Jakub Karczmarski, Maria Kulecka, Agnieszka Paziewska, Magdalena Niemira, Natalia Zeber-Lubecka, Edyta Zagorowicz, Adam Kretowski and Jerzy Ostrowski

    Citation: BMC Gastroenterology 2020 20:307

    Content type: Research article

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  5. Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed to establish a new model combing the inflammatory markers including neutrophil/lymphocyte r...

    Authors: Li Qiang, Jiao Qin, Changfeng Sun, Yunjian Sheng, Wen Chen, Bangdong Qiu, Xin Chen, Yuanfang Chen, Fei Liu and Gang Wu

    Citation: BMC Gastroenterology 2020 20:301

    Content type: Research article

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  6. Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common gastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their ...

    Authors: Mohammad Karimian, Hassan Nourmohammadi, Majid Salamati, Mohammad Reza Hafezi Ahmadi, Fatemeh Kazemi and Milad Azami

    Citation: BMC Gastroenterology 2020 20:297

    Content type: Research article

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  7. Amebiasis is a rare condition in developed countries but epidemiologically growing. Clinical manifestation may range from asymptomatic to invasive disease, amoebic liver abscess being the most common manifesta...

    Authors: Matteo Borro, Giuseppe Murdaca, Monica Greco, Simone Negrini and Maurizio Setti

    Citation: BMC Gastroenterology 2020 20:295

    Content type: Case report

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  8. The prevalence of chronic constipation is increased in females and with age or environmental (low temperature), racial, socioeconomic, and habitual risk factors. The impact of low outside temperature on consti...

    Authors: Hiroshi Mihara, Aiko Murayama, Sohachi Nanjo, Takayuki Ando, Kazuto Tajiri, Haruka Fujinami, Masaaki Yamada and Ichiro Yasuda

    Citation: BMC Gastroenterology 2020 20:284

    Content type: Research article

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  9. Reflux esophagitis (RE) and absence of Helicobacter pylori (non-H. pylori) are considered to be associated with the progression to long-segment Barrett’s esophagus (LSBE). However, it is difficult to assess this ...

    Authors: Genki Usui, Tomohiro Shinozaki, Toyohisa Jinno, Kazutoshi Fujibayashi, Teppei Morikawa, Toshiaki Gunji and Nobuyuki Matsuhashi

    Citation: BMC Gastroenterology 2020 20:270

    Content type: Research article

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  10. Hypereosinophilic syndrome (HES) is a very rare disease and usually treated with corticosteroids. Gastrointestinal (GI) cytomegalovirus (CMV) infection is also rare but frequent in patients with immunocompromi...

    Authors: Bin Luo, Chengxin Deng, Tieying Hou, Fangping Xu, Qianchao Liao, Yong Li and Junjiang Wang

    Citation: BMC Gastroenterology 2020 20:238

    Content type: Case report

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  12. Gastric cancer develops even in Helicobacter pylori(H. pylori)-uninfected patients and its typical histological feature is signet ring cell carcinoma (SRCC) within the mucosal layer. However, the biological chara...

    Authors: Mariko Kiso, Yuji Urabe, Masanori Ito, Kazuhiko Masuda, Tomoyuki Boda, Takahiro Kotachi, Kosaku Hata, Naoki Yorita, Naoko Nagasaki, Madina Abduwali, Yuich Hiyama, Shiro Oka, Shinji Tanaka and Kazuaki Chayama

    Citation: BMC Gastroenterology 2020 20:243

    Content type: Research article

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  13. Inpatient status has been shown to be a predictor of poor bowel preparation for colonoscopy; however, the optimal bowel preparation regimen for hospitalized patients is unknown. Our aim was to compare the effi...

    Authors: Patricia V. Hernandez, Jennifer L. Horsley-Silva, Diana L. Snyder, Noemi Baffy, Mary Atia, Laura Koepke, Matthew R. Buras, Elisabeth S. Lim, Kevin Ruff, Sarah B. Umar, Sameer Islam and Francisco C. Ramirez

    Citation: BMC Gastroenterology 2020 20:227

    Content type: Research article

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  14. Patients co-infected with hepatitis B virus (HBV) and the human immunodeficiency virus (HIV) are at risk of developing hepatocellular carcinoma (HCC). In sub-Saharan Africa, the overlap between high HIV and HB...

    Authors: Tongai Gibson Maponga, Richard H. Glashoff, Hannali Vermeulen, Barbara Robertson, Sean Burmeister, Marc Bernon, Jones Omoshoro-Jones, Paul Ruff, Alfred I. Neugut, Judith S. Jacobson, Wolfgang Preiser and Monique I. Andersson

    Citation: BMC Gastroenterology 2020 20:226

    Content type: Research article

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  15. Intestinal and diffuse gastric adenocarcinomas differ in clinical, epidemiological and molecular features. However, most of the concepts related to the intestinal-type are translated to gastric adenocarcinoma ...

    Authors: Paulo Pimentel Assumpção, Williams Fernandes Barra, Geraldo Ishak, Luiz Gonzaga Vaz Coelho, Felipe José Fernandez Coimbra, Helano Carioca Freitas, Emmanuel Dias-Neto, M. Constanza Camargo and Moyses Szklo

    Citation: BMC Gastroenterology 2020 20:223

    Content type: Debate

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  16. Previous studies of the relationship between dietary factors and risk of diverticulosis have yielded inconsistent results. We therefore sought to investigate the association between consumption of fruit and ve...

    Authors: Benjamin Maxner, Jessica McGoldrick, Danielle Bellavance, Po-Hong Liu, Ramnik J. Xavier, Joseph C. Yarze, Rocco Ricciardi, Kyle Staller, Daniel C. Chung and Hamed Khalili

    Citation: BMC Gastroenterology 2020 20:221

    Content type: Research article

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  17. Whipple’s disease is a rare systemic disease caused by a gram-positive bacillus called Tropheryma whipplei. First described in 1907 as an intestinal lipodystrophy with histological finding of vacuoles in the m...

    Authors: Margarita Rey R., Luis Alejandro Orozco, Katherine Marrugo, Rocio López, Erika D. Pérez-Riveros, José De la Hoz-Valle and Fernando Sierra-Arango

    Citation: BMC Gastroenterology 2020 20:197

    Content type: Case report

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  18. Non Helicobacter pylori gastric Helicobacters (NHPGHs) are associated with a range of upper gastrointestinal symptoms, histologic and endoscopic findings. For the first time in Iran, we performed a cross-sectiona...

    Authors: Shakiba Shafaie, Hami Kaboosi and Fatemeh Peyravii Ghadikolaii

    Citation: BMC Gastroenterology 2020 20:190

    Content type: Research article

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  19. Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disease characterized by multifocal venous malformations. It remains a considerable challenge in treating the gastrointestinal (GI) venous malformat...

    Authors: Yuemei Xu, Yingjie Wu, Zhenzhen Dai, Feizhen Xia and Feng Xu

    Citation: BMC Gastroenterology 2020 20:182

    Content type: Case report

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  20. Abdominal pain in adults represents a wide range of illnesses, often warranting immediate intervention. This study is to fill the gap in the knowledge about incidence, presentation, causes and mortality from a...

    Authors: Kilalo M. Mjema, Hendry R. Sawe, Irene Kulola, Amour S. Mohamed, Erasto Sylvanus, Juma A. Mfinanga and Ellen J. Weber

    Citation: BMC Gastroenterology 2020 20:173

    Content type: Research article

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  21. Diagnosing constipation remains difficult and its treatment continues to be ineffective. The reason may be that the symptom patterns of constipation differ in different demographic groups. We aimed to determin...

    Authors: Sanne J. Verkuijl, Rob J. Meinds, Monika Trzpis and Paul M. A. Broens

    Citation: BMC Gastroenterology 2020 20:168

    Content type: Research article

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  22. Post-infectious Irritable Bowel Syndrome (PI-IBS) is a functional bowel disorder which has significant impacts to a patient’s quality of life. No IBS-specific biomarker or treatment regimen for PI-IBS currentl...

    Authors: Erika Austhof, Kenzie Schaefer, Jaime Faulkner, Laura Bach, Mark Riddle and Kristen Pogreba-Brown

    Citation: BMC Gastroenterology 2020 20:159

    Content type: Research article

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  23. Incidence of ulcerative colitis (UC) in elderly population is increasing because of ageing and because of its minimal impact on life span. Data on natural history, outcomes and therapeutic strategies are limited.

    Authors: Irene Zammarchi, Francesco Lanzarotto, Rosanna Cannatelli, Francesca Munari, Federica Benini, Alessandro Pozzi, Alberto Lanzini and Chiara Ricci

    Citation: BMC Gastroenterology 2020 20:147

    Content type: Research article

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  24. Abdominal pain may be a presenting symptom of lead poisoning and is often difficult to diagnose. This study aimed to determine the prevalence of abdominal pain in patients seen in the Laghman Hakim Hospital ED...

    Authors: Mahtab Shabani, Seyed Kaveh Hadeiy, Parinaz Parhizgar, Nasim Zamani, Hamid Mehrad, Hossein Hassanian-Moghaddam and Scott Phillips

    Citation: BMC Gastroenterology 2020 20:134

    Content type: Research article

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  25. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are considered to reflect the systemic inflammatory response and clinical prognosis. However, the independent prognostic values o...

    Authors: Wei-Long Chang, Wen-Chang Yang, Xiang-Yu Zeng, Cheng-Guo Li, Zhen Xiong, Tao Wang, Rui-Zhi Zhang, Kai-Xiong Tao and Peng Zhang

    Citation: BMC Gastroenterology 2020 20:124

    Content type: Research article

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  26. Esophagogastroduodenoscopy (EGD) provides an indispensable and unambiguous inspection allowing the discovery upper gastrointestinal lesions. However, many patients are anxious about undergoing EGD. Few studies...

    Authors: Masahiro Sogabe, Toshiya Okahisa, Akira Fukuya, Kaizo Kagemoto, Yasuyuki Okada, Yuka Adachi, Takeshi Kurihara, Toru Nii, Satoshi Teramae, Hironori Tanaka, Tetsu Tomonari, Koichi Okamoto, Hiroshi Miyamoto, Masahiko Nakasono and Tetsuji Takayama

    Citation: BMC Gastroenterology 2020 20:122

    Content type: Research article

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  27. The prevalence of gastroesophageal reflux disease (GERD) in Africa is not known but is believed to be increasing because of demographic and epidemiologic transition. The main objectives of this study were to d...

    Authors: Sylvester Chuks Nwokediuko, Olusegun Adekanle, Adegboyega Akere, Abdulfatai Olokoba, Chiedozie Anyanechi, Sabo Mustapha Umar, Abubakar Maiyaki, Uchenna Ijoma, Olive Obienu, Augustine Uhunmwangho and Dennis Ndububa

    Citation: BMC Gastroenterology 2020 20:107

    Content type: Research article

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  28. The Gut and Obesity in Asia (GOASIA) Workgroup was formed to study obesity and gastrointestinal diseases in the Asia Pacific region. We aimed to 1) compare the characteristics of elderly (i.e. age ≥ 60) vs. no...

    Authors: Panyavee Pitisuttithum, Wah Kheong Chan, Panida Piyachaturawat, Kento Imajo, Atsushi Nakajima, Yosuke Seki, Kazunori Kasama, Satoru Kakizaki, Jian Gao Fan, Myeong Jun Song, Seung Kew Yoon, Yock Young Dan, Laurentius Lesmana, Khek Yu Ho, Khean Lee Goh, Vincent Wai Sun Wong…

    Citation: BMC Gastroenterology 2020 20:88

    Content type: Research article

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  29. The incidence of cirrhosis for individuals in Sweden has previously been reported as stable/low among European countries. However, Swedish population-based studies are scarce and none of them included data fro...

    Authors: Juan Vaz, Berne Eriksson, Ulf Strömberg, David Buchebner and Patrik Midlöv

    Citation: BMC Gastroenterology 2020 20:84

    Content type: Research article

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  30. There are several studies with varied and mixed results about the possible relationship between H. pylori and diabetes. Therefore, this current meta-analysis performed to determine the association between H. pylo...

    Authors: Kamyar Mansori, Yousef Moradi, Sara Naderpour, Roya Rashti, Ali Baradaran Moghaddam, Lotfolah Saed and Hedyeh Mohammadi

    Citation: BMC Gastroenterology 2020 20:77

    Content type: Research article

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  31. Advances in surgical techniques and perioperative care have improved the short- and mid-term postoperative outcomes of patients with Hirschsprung disease (HD). However, the long-term outcomes of these patients...

    Authors: Ying Dai, Yongfang Deng, Yan Lin, Runxian Ouyang and Le Li

    Citation: BMC Gastroenterology 2020 20:67

    Content type: Research article

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  32. Gastroesophageal reflux disease (GORD) is a chronic and a common condition worldwide which causes mild to severe symptoms. Private tuition attendees are a group which could have potential risk factors for GORD...

    Authors: Darsha Gunasinghe, Chathurika Gunawardhana, Shakthi Halahakoon, Ali Haneeka, Najiyya Hanim, Chamara Hapuarachchi and Devarajan Rathish

    Citation: BMC Gastroenterology 2020 20:45

    Content type: Research article

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  33. Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. Studies have shown that sleep apnea is associated with NAFLD. However, studies on the association between sleep disord...

    Authors: Yu-Ting Wei, Peng-Yi Lee, Cheng-Yu Lin, Hsuan-Ju Chen, Che-Chen Lin, Jin-Shang Wu, Yin-Fan Chang, Chen-Long Wu and How-Ran Guo

    Citation: BMC Gastroenterology 2020 20:32

    Content type: Research article

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  34. This study aimed to summarize the previously published literature on the role of platelet-to-lymphocyte ratio (PLR) on overall survival (OS) in patients with gastric cancer.

    Authors: Weijuan Cao, Xiaomin Yao, Danwei Cen, Yajun Zhi, Ningwei Zhu and Liyong Xu

    Citation: BMC Gastroenterology 2020 20:16

    Content type: Research article

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  35. The impact of liver cirrhosis on the outcomes of admission to intensive care unit (ICU) is not completely understood. Our purpose is to identify risk factors for mortality in ICU patients with liver cirrhosis.

    Authors: Yu-Feng Huang, Chao-Shun Lin, Yih-Giun Cherng, Chun-Chieh Yeh, Ray-Jade Chen, Ta-Liang Chen and Chien-Chang Liao

    Citation: BMC Gastroenterology 2020 20:15

    Content type: Research article

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  36. Previous studies have indicated that disease activity, psychological symptoms and social support were associated with health-related quality of life (HRQoL) in patients with inflammatory bowel diseases(IBD). H...

    Authors: Hanlin Fu, Atipatsa Chiwanda Kaminga, Yan Peng, Tiejian Feng, Tingting Wang, Xiaobing Wu and Tubao Yang

    Citation: BMC Gastroenterology 2020 20:11

    Content type: Research article

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  37. Little is known about the natural history of serrated polyps (SPs), partly due to the lack of large-scale epidemiologic data. In this study, we examined the validity of SP identification according to SNOMED (S...

    Authors: Soran R. Bozorg, Mingyang Song, Louise Emilsson and Jonas F. Ludvigsson

    Citation: BMC Gastroenterology 2019 20:3

    Content type: Research article

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  38. Upper gastrointestinal bleeding (UGIB) is a common emergency department (ED) presentation with high morbidity and mortality. There is a paucity of data on the profile and outcome of patients who present with U...

    Authors: Shaffin S. Rajan, Hendry R. Sawe, Asha J. Iyullu, Dereck A. Kaale, Nancy A. Olambo, Juma A. Mfinanga and Ellen J. Weber

    Citation: BMC Gastroenterology 2019 19:212

    Content type: Research article

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  39. Irritable bowel syndrome (IBS) is prevalent in patients with morbid obesity. After Roux-en-Y gastric bypass (RYGB) chronic abdominal pain is common, however the etiology is largely unknown. We aimed to study t...

    Authors: Ingvild Kristine Blom-Høgestøl, Martin Aasbrenn, Monica Chahal-Kummen, Cathrine Brunborg, Inger Eribe, Jon Kristinsson, Per G. Farup and Tom Mala

    Citation: BMC Gastroenterology 2019 19:204

    Content type: Research article

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  40. Only a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylor...

    Authors: Wenhai Wang, Wei Jiang, Shengtao Zhu, Xiujing Sun, Peng Li, Kejia Liu, Henghui Liu, Junchao Gu and Shutian Zhang

    Citation: BMC Gastroenterology 2019 19:186

    Content type: Research article

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  41. Studies indicate that gastric cancer (GC) incidence has decreased, whereas signet ring cell carcinoma (SRC) incidence has increased. However, recent trends in GC incidence are unclear. We used our hospital can...

    Authors: Hiroshi Ohyama, Dai Yoshimura, Yosuke Hirotsu, Kenji Amemiya, Hiroyuki Amano, Yuko Miura, Hiroshi Ashizawa, Keiko Nakagomi, Shinya Takaoka, Kenji Hosoda, Yoji Suzuki, Toshio Oyama, Masao Hada, Yuichiro Kojima, Hitoshi Mochizuki and Masao Omata

    Citation: BMC Gastroenterology 2019 19:178

    Content type: Research article

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  43. The pattern and distribution of human rotavirus genotypes in young children in developing countries play an important role in epidemiological studies, as well as providing a strategy for the development of fut...

    Authors: Nazanin Lorestani, Abdolvahhab Moradi, Ali Teimoori, Maha Masodi, Sayyad Khanizadeh, Mina Hassanpour, Naemeh Javid, Abdollah Ardebili, Alijan Tabarraei and Hadi Razavi Nikoo

    Citation: BMC Gastroenterology 2019 19:100

    Content type: Research article

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  44. Children in poor areas show significant growth retardation that does not improve with an adequate supply of energy and nutrients, which may be related to asymptomatic intestinal infection caused by poor sanita...

    Authors: Xiaoyang Sheng, Xueqing Sun, Feng Li, Junli Wang and Jingqiu Ma

    Citation: BMC Gastroenterology 2019 19:96

    Content type: Research article

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  45. Different definitions of constipation have been used to estimate its prevalence in the community but this creates difficulties when comparing results from various studies. This study explores the impact of dif...

    Authors: Barry L. Werth, Kylie A. Williams, Murray J. Fisher and Lisa G. Pont

    Citation: BMC Gastroenterology 2019 19:75

    Content type: Research article

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  46. The global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other developing nations of the world. Development of H. pylori-assoc...

    Authors: Ayodeji Idowu, Asisipho Mzukwa, Ute Harrison, Pia Palamides, Rainer Haas, Melvin Mbao, Razinah Mamdoo, Jonathan Bolon, Tolulope Jolaiya, Stella Smith, Reidwaan Ally, Anna Clarke and Henry Njom

    Citation: BMC Gastroenterology 2019 19:73

    Content type: Research article

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  47. Hepatic steatosis is prevalent in Western countries, but few studies have evaluated whether the frequency and severity of steatosis are greater in the setting of HIV infection. We compared the prevalence and s...

    Authors: Jessie Torgersen, Kaku So-Armah, Matthew S. Freiberg, Matthew B. Goetz, Matthew J. Budoff, Joseph K. Lim, Tamar Taddei, Adeel A. Butt, Maria C. Rodriguez-Barradas, Amy C. Justice, Jay R. Kostman and Vincent Lo Re III

    Citation: BMC Gastroenterology 2019 19:52

    Content type: Research article

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  48. Helicobacter pylori (H.pylori) infections are prevalent and recognized as major cause of gastrointestinal diseases in Ethiopia. However, Studies conducted on the prevalence, risk factors and other clinical forms ...

    Authors: Addisu Melese, Chalachew Genet, Balew Zeleke and Tesfaye Andualem

    Citation: BMC Gastroenterology 2019 19:8

    Content type: Research article

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  49. The long-term natural history of microscopic colitis (MC) (collagenous colitis (CC), lymphocytic colitis (LC)), traditionally considered relapsing but non-progressive diseases, is poorly defined. Whether persi...

    Authors: Alexander Levy, Nienke Z. Borren, Benjamin Maxner, William Tan, Danielle Bellavance, Kyle Staller, Daniel Chung, Hamed Khalili and Ashwin N. Ananthakrishnan

    Citation: BMC Gastroenterology 2019 19:1

    Content type: Research article

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