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Epidemiology of gastroenterological disorders

This section aims to publish research on the prevalence and the environmental, behavioral, dietary and occupational correlates of gastrointestinal and hepatobiliary disorders

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  1. Content type: Research article

    Different definitions of constipation have been used to estimate its prevalence in the community but this creates difficulties when comparing results from various studies. This study explores the impact of dif...

    Authors: Barry L. Werth, Kylie A. Williams, Murray J. Fisher and Lisa G. Pont

    Citation: BMC Gastroenterology 2019 19:75

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  2. Content type: Research article

    The global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other developing nations of the world. Development of H. pylori-assoc...

    Authors: Ayodeji Idowu, Asisipho Mzukwa, Ute Harrison, Pia Palamides, Rainer Haas, Melvin Mbao, Razinah Mamdoo, Jonathan Bolon, Tolulope Jolaiya, Stella Smith, Reidwaan Ally, Anna Clarke and Henry Njom

    Citation: BMC Gastroenterology 2019 19:73

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  3. Content type: Research article

    Hepatic steatosis is prevalent in Western countries, but few studies have evaluated whether the frequency and severity of steatosis are greater in the setting of HIV infection. We compared the prevalence and s...

    Authors: Jessie Torgersen, Kaku So-Armah, Matthew S. Freiberg, Matthew B. Goetz, Matthew J. Budoff, Joseph K. Lim, Tamar Taddei, Adeel A. Butt, Maria C. Rodriguez-Barradas, Amy C. Justice, Jay R. Kostman and Vincent Lo Re III

    Citation: BMC Gastroenterology 2019 19:52

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  4. Content type: Research article

    Helicobacter pylori (H.pylori) infections are prevalent and recognized as major cause of gastrointestinal diseases in Ethiopia. However, Studies conducted on the prevalence, risk factors and other clinical forms ...

    Authors: Addisu Melese, Chalachew Genet, Balew Zeleke and Tesfaye Andualem

    Citation: BMC Gastroenterology 2019 19:8

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  5. Content type: Research article

    The long-term natural history of microscopic colitis (MC) (collagenous colitis (CC), lymphocytic colitis (LC)), traditionally considered relapsing but non-progressive diseases, is poorly defined. Whether persi...

    Authors: Alexander Levy, Nienke Z. Borren, Benjamin Maxner, William Tan, Danielle Bellavance, Kyle Staller, Daniel Chung, Hamed Khalili and Ashwin N. Ananthakrishnan

    Citation: BMC Gastroenterology 2019 19:1

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  7. Content type: Research article

    Gallbladder Polyps (GBP) are highly prevalent in China; however, the etiology of GBP has not been clearly defined. This study explored the associations between lifestyle factors and GBP and whether it mediated...

    Authors: Song Leng, Ai Zhao, Qiang Li, Leilei Pei, Wei Zheng, Rui Liang and Hong Yan

    Citation: BMC Gastroenterology 2018 18:159

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  8. Content type: Research article

    The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylor...

    Authors: Huiying Shi, Hanhua Xiong, Wei Qian and Rong Lin

    Citation: BMC Gastroenterology 2018 18:158

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  9. Content type: Research article

    Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk facto...

    Authors: Qianqian Zhu, Xianlong Li, Fang Tan, Yingqing Deng, Chulian Gong, Jingping Hu, Pinjie Huang and Shaoli Zhou

    Citation: BMC Gastroenterology 2018 18:152

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  10. Content type: Research article

    Existing data about the prognostic value of absolute count of blood cells in gastric cancer was limited. Thus, the present study aims to investigate the prognostic value of absolute count of white blood cell (...

    Authors: Fan Feng, Gaozan Zheng, Qiao Wang, Shushang Liu, Zhen Liu, Guanghui Xu, Fei Wang, Man Guo, Xiao Lian and Hongwei Zhang

    Citation: BMC Gastroenterology 2018 18:148

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  11. Content type: Research article

    We aimed to study the epidemiology and risk factors, including exposure to emotional stress, for constipation in Indonesian children and adolescents of 10–17 year age group.

    Authors: Hanifah Oswari, Fatima Safira Alatas, Badriul Hegar, William Cheng, Arnesya Pramadyani, Marc Alexander Benninga and Shaman Rajindrajith

    Citation: BMC Gastroenterology 2018 18:146

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  13. Content type: Research article

    Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from...

    Authors: Danielle C. Sample, N. Jewel Samadder, Lisa M. Pappas, Kenneth M. Boucher, Wade S. Samowitz, Therese Berry, Michelle Westover, Deepika Nathan, Priyanka Kanth, Kathryn R. Byrne, Randall W. Burt and Deborah W. Neklason

    Citation: BMC Gastroenterology 2018 18:115

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  15. Content type: Research article

    This study aims to compare the performance of AIMS65, Glasgow–Blatchford (GBS) and Rockall scores (RS) in predicting the death risk among emergency-hospitalized patients with upper gastrointestinal bleeding (U...

    Authors: Lei Gu, Fei Xu and Jie Yuan

    Citation: BMC Gastroenterology 2018 18:98

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  16. Content type: Research article

    Current available treatments for Helicobacter pylori eradication are chosen according to local clarithromycin and metronidazole resistance prevalence. The aim of this study was to estimate, by means of molecular ...

    Authors: Patricio Gonzalez-Hormazabal, Maher Musleh, Susana Escandar, Hector Valladares, Enrique Lanzarini, V. Gonzalo Castro, Lilian Jara and Zoltan Berger

    Citation: BMC Gastroenterology 2018 18:91

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  17. Content type: Research article

    The epidemiology of inflammatory bowel disease (IBD) varies in different countries. This study aimed to assess phenotype, medications, prevalence and incidence of IBD in the State of Espírito Santo, Brazil.

    Authors: Adalberta Lima Martins, Rhaisa Almeida Volpato and Maria da Penha Zago-Gomes

    Citation: BMC Gastroenterology 2018 18:87

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  18. Content type: Research article

    The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli), particularly E. coli sequence type ST131, is becoming a global concern. Commensal bacteria, an important reservoir of antibiotic resistance g...

    Authors: I-Fei Huang, Wei-Yang Lee, Jiun-Ling Wang, Chih-Hsin Hung, Hong-Hsiang Hu, Wan-Yu Hung, Yun-Ju Hung, Wen-Chi Chen, Ying-Tso Shen and Ming-Fang Cheng

    Citation: BMC Gastroenterology 2018 18:86

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  19. Content type: Research article

    Obesity is a known risk factor for erosive esophagitis (EE) and metabolic unhealthiness has been implicated in EE pathogenesis. However, obesity and metabolic unhealthiness are not synonymous and the associati...

    Authors: Myong Ki Baeg, Sun-Hye Ko, Seung Yeon Ko, Hee Sun Jung and Myung-Gyu Choi

    Citation: BMC Gastroenterology 2018 18:82

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  20. Content type: Research article

    Helicobacter pylori (H. pylori) infection is a worldwide threat to human health with high prevalence. In this study, we analyzed the relationship between latitude, average annual temperature, average daily sunshi...

    Authors: Chao Lu, Ye Yu, Lan Li, Chaohui Yu and Ping Xu

    Citation: BMC Gastroenterology 2018 18:50

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  22. Content type: Research article

    Chronic abdominal pain is a common worldwide problem and known to be associated with psychological problems. This study evaluated the association between abdominal pain-predominant functional gastrointestinal ...

    Authors: Nishadi Ranasinghe, Niranga Manjuri Devanarayana, Shaman Rajindrajith, Madusanka S. Perera, Samudu Nishanthinie, Tania Warnakulasuriya and Piyanjali Thamesha de Zoysa

    Citation: BMC Gastroenterology 2018 18:33

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  23. Content type: Research article

    Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence o...

    Authors: Stian Magnus Staurung Orlien, Nejib Yusuf Ismael, Tekabe Abdosh Ahmed, Nega Berhe, Trine Lauritzen, Borghild Roald, Robert David Goldin, Kathrine Stene-Johansen, Anne Margarita Dyrhol-Riise, Svein Gunnar Gundersen, Marsha Yvonne Morgan and Asgeir Johannessen

    Citation: BMC Gastroenterology 2018 18:27

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  24. Content type: Research article

    Accelerated treatment strategy, including tight disease control and early aggressive therapy with immunosuppressives (IS) and biological agents have become increasingly common in inflammatory bowel disease (IB...

    Authors: Zsuzsanna Kurti, Akos Ilias, Lorant Gonczi, Zsuzsanna Vegh, Petra Fadgyas-Freyler, Gyula Korponay, Petra A. Golovics, Barbara D. Lovasz and Peter L. Lakatos

    Citation: BMC Gastroenterology 2018 18:23

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  25. Content type: Research article

    Although subacute and chronic gastrointestinal symptoms are very common in primary care, epidemiological date are sparse. The aim of the study was to examine and quantify the prevalence of subacute and chronic...

    Authors: Maria Avramidou, Felix Angst, Jules Angst, André Aeschlimann, Wulf Rössler and Ulrich Schnyder

    Citation: BMC Gastroenterology 2018 18:21

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  26. Content type: Research article

    Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The...

    Authors: Abdurahaman Seid, Zemenu Tamir and Wondmagegn Demsiss

    Citation: BMC Gastroenterology 2018 18:13

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  27. Content type: Research article

    Nutrition support is a common means for patients with gastric cancer, especially for those undergoing elective surgery. Recently, enteral immunonutrition (EIN) was increasingly found to be more effective than ...

    Authors: Ying Cheng, Junfeng Zhang, Liwei Zhang, Juan Wu and Zhen Zhan

    Citation: BMC Gastroenterology 2018 18:11

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  28. Content type: Research article

    The risk of Hepatitis B virus (HBV) reactivation in patients with different hematological malignancy except lymphoma were rarely known before.

    Authors: Chien-Yuan Chen, Feng-Ming Tien, Aristine Cheng, Shang-Yi Huang, Wen-Chien Chou, Ming Yao, Jih-Luh Tang, Hwei-Fang Tien and Wang-Huei Sheng

    Citation: BMC Gastroenterology 2018 18:6

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  29. Content type: Research article

    Children and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limit...

    Authors: Laura Mählmann, Markus Gerber, Raoul I. Furlano, Corinne Legeret, Nadeem Kalak, Edith Holsboer-Trachsler and Serge Brand

    Citation: BMC Gastroenterology 2017 17:160

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  30. Content type: Research article

    Gastric cancer (GC) has a poor prognosis with wide variation in survival rates across the world. Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (IM) influence ga...

    Authors: Andrew D. Spence, Chris R. Cardwell, Úna C. McMenamin, Blanaid M. Hicks, Brian T. Johnston, Liam J. Murray and Helen G. Coleman

    Citation: BMC Gastroenterology 2017 17:157

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  31. Content type: Research article

    Gallbladder disease (GBD) is a highly prevalent condition; however, little is known about potential differences in risk factors by sex and ethnicity/race. Our aim was to evaluate dietary, reproductive and obes...

    Authors: Jane C. Figueiredo, Christopher Haiman, Jacqueline Porcel, James Buxbaum, Daniel Stram, Neal Tambe, Wendy Cozen, Lynne Wilkens, Loic Le Marchand and Veronica Wendy Setiawan

    Citation: BMC Gastroenterology 2017 17:153

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  32. Content type: Research article

    Real-life data on inflammatory bowel disease (IBD) prevalence and costs are scarce. The aims of this study were to provide an overview of the prevalence, mortality, health care utilization and costs of IBD pat...

    Authors: Caroline Bähler, Stephan R. Vavricka, Alain M. Schoepfer, Beat Brüngger and Oliver Reich

    Citation: BMC Gastroenterology 2017 17:138

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  33. Content type: Research article

    Very few studies report on the prevalence of irritable bowel syndrome (IBS) and its correlates in the Middle East. This study investigated Irritable Bowel Syndrome (IBS) prevalence in a sample of Lebanese adul...

    Authors: Rajaa Chatila, Mahmoud Merhi, Essa Hariri, Nada Sabbah and Mary E. Deeb

    Citation: BMC Gastroenterology 2017 17:137

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  34. Content type: Research article

    In clinical practice, assessment of constipation depends on reliability, consistency and frequency of several commonly reported or core symptoms. It is not known if frequency patterns of constipation symptoms ...

    Authors: Abdul Wahab Patimah, Yeong Yeh Lee and Mohd Yusoff Dariah

    Citation: BMC Gastroenterology 2017 17:115

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  35. Content type: Research article

    The global burden of liver diseases, such as hepatocellular carcinoma and liver cirrhosis, is substantial. In this study, we estimated utility weights of liver disease-related health states in the general popu...

    Authors: Minsu Ock, So Yun Lim, Hyeon-Jeong Lee, Seon-Ha Kim and Min-Woo Jo

    Citation: BMC Gastroenterology 2017 17:103

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  36. Content type: Research article

    Gastroesophageal reflux disease (GERD), functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common functional gastrointestinal conditions with a significant impact on daily life. The objectives we...

    Authors: Dorte Ejg Jarbøl, Sanne Rasmussen, Kirubakaran Balasubramaniam, Sandra Elnegaard and Peter Fentz Haastrup

    Citation: BMC Gastroenterology 2017 17:65

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  37. Content type: Research article

    Helicobacter pylori (HP) infection is present in about 50% of the global population, and is associated with chronic gastritis, peptic disease and gastric malignancies. HP prevalence in Crohn’s disease (CD) pat...

    Authors: Adi Lahat, Uri Kopylov, Sandra Neuman, Nina Levhar, Doron Yablecovitch, Benjamin Avidan, Batia Weiss, Shomron Ben-Horin and Rami Eliakim

    Citation: BMC Gastroenterology 2017 17:27

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  38. Content type: Research article

    The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).

    Authors: Dorota Koziel, Stanislaw Gluszek, Artur Kowalik and Malgorzata Chlopek

    Citation: BMC Gastroenterology 2017 17:13

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  39. Content type: Research article

    The association between stress and peptic ulcers has been questioned since the discovery of helicobacter pylori. This study examined whether high perceived everyday life stress was associated with an increased ri...

    Authors: Ulrik Deding, Linda Ejlskov, Mads Phillip Kofoed Grabas, Berit Jamie Nielsen, Christian Torp-Pedersen and Henrik Bøggild

    Citation: BMC Gastroenterology 2016 16:140

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  40. Content type: Research article

    Immunoglobulin A (IgA) antibodies to tissue transglutaminase (tTG) are the serologic test of choice for diagnosing celiac disease (CD). Our aim was to determine if elevated IgA anti-tTG were associated with in...

    Authors: Alberto Rubio-Tapia, Jonas F. Ludvigsson, Rok Seon Choung, Tricia L. Brantner, S. Vincent Rajkumar, Ola Landgren and Joseph A. Murray

    Citation: BMC Gastroenterology 2016 16:136

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  41. Content type: Research article

    While mortality in the United States has decreased for most cancers, mortality from combined hepatocellular liver cancer and intrahepatic cholangiocarcinoma (ICC) has increased and ranked 1st in annual percent...

    Authors: Kaelan J. Yao, Salma Jabbour, Niyati Parekh, Yong Lin and Rebecca A. Moss

    Citation: BMC Gastroenterology 2016 16:117

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  42. Content type: Research article

    Gastric cancer is the fourth most common cancer worldwide and more frequently detected in Asian countries including Korea and Japan. The incidence of young-age gastric cancer (GC) is increasing worldwide, but ...

    Authors: Jieun Lee, Myung Ah Lee, In-Ho Kim and Sang-Young Roh

    Citation: BMC Gastroenterology 2016 16:110

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  43. Content type: Research article

    Hepatitis B virus (HBV) genotype and its role in disease progression and patients’ response to antiviral treatment, is not well studied in Pakistan. This comprehensive study was aimed to determine the distribu...

    Authors: Majid Mahmood, Muhammad Asim Anwar, Azra Khanum, Nasib Zaman and Abida Raza

    Citation: BMC Gastroenterology 2016 16:104

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  44. Content type: Research article

    Colorectal cancer and its precursors are highly prevalent in developed countries. Estimates in the available literature for prevalence of right-sided-only lesions vary between 20.5 and 48.1 %, with association...

    Authors: Heather S. Laird-Fick, Gurveen Chahal, Ade Olomu, Joseph Gardiner, James Richard and Nikolay Dimitrov

    Citation: BMC Gastroenterology 2016 16:90

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  45. Content type: Research article

    Evidence supporting the associations between folate metabolizing gene polymorphisms and pancreatic cancer has been inconclusive. We examined their associations in a case-control study of Japanese subjects.

    Authors: Haruhisa Nakao, Kenji Wakai, Norimitsu Ishii, Yuji Kobayashi, Kiyoaki Ito, Masashi Yoneda, Mitsuru Mori, Masanori Nojima, Yasutoshi Kimura, Takao Endo, Masato Matsuyama, Hiroshi Ishii, Makoto Ueno, Sawako Kuruma, Naoto Egawa, Keitaro Matsuo…

    Citation: BMC Gastroenterology 2016 16:83

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  46. Content type: Research article

    Recent studies have implicated that members of the DICKKOPF (DKK) were causally involved in large number of human cancers. This study was designed to investigate the relationship between the genetic variations of...

    Authors: Juan Wu, Junfeng Zhang, Zhen Zhan, Qinhong Cao and Zhong Li

    Citation: BMC Gastroenterology 2016 16:78

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  47. Content type: Research article

    Although heavy drinking is known to lead to liver injury, some recent studies have reported that light alcohol consumption (LAC) may play a protective role against fatty liver in the general population, and ma...

    Authors: Masahiro Sogabe, Toshiya Okahisa, Tadahiko Nakagawa, Hiroshi Fukuno, Masahiko Nakasono, Tetsu Tomonari, Takahiro Tanaka, Hironori Tanaka, Tatsuya Taniguchi, Naoki Muguruma and Tetsuji Takayama

    Citation: BMC Gastroenterology 2016 16:17

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  48. Content type: Research article

    Hereditary transthyretin amyloid (ATTR) amyloidosis is a rare but fatal autosomal dominant condition that is present all over the world. A liver transplantation has been shown to halt the progress of the disea...

    Authors: Jonas Wixner, Torbjörn Sundström, Pontus Karling, Intissar Anan and Ole B Suhr

    Citation: BMC Gastroenterology 2015 15:51

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  49. Content type: Research article

    Nicotinamide phosphoribosyl transferase (Nampt) plays a crucial role in tumorigenesis. The present study examines whether genetic polymorphisms of NAMPT are related to the risk of developing esophageal squamous c...

    Authors: Chuanzhen Zhang, Daojie Yan, Shanshan Wang, Changqing Xu, Wenjun Du, Tao Ning, Changhong Liu, Meijuan Zhang, Ruiping Hou and Ziping Chen

    Citation: BMC Gastroenterology 2015 15:49

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  50. Content type: Research article

    The presence of diabetes mellitus (DM) is associated with increased liver morbidity and mortality risk in patients with chronic hepatitis B (CHB). Aim of this study was to identify factors associated with type...

    Authors: Yi Shen, Jian Zhang, Hui Cai, Jian-Guo Shao, You-Yi Zhang, Yan-Mei Liu, Gang Qin and Yan Qin

    Citation: BMC Gastroenterology 2015 15:32

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