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Epidemiology of gastroenterological disorders

This section aims to publish research on the prevalence and the environmental, behavioral, dietary and occupational correlates of gastrointestinal and hepatobiliary disorders

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  1. We previously reported on the trends in the etiologies of hepatocellular carcinoma (HCC) diagnosed in patients between 1995 and 2009. The aims of our updated study were to evaluate the incidence, nonhepatitis...

    Authors: Yuko Nagaoki, Hideyuki Hyogo, Yuwa Ando, Yumi Kosaka, Shinsuke Uchikawa, Yuno Nishida, Yuji Teraoka, Kei Morio, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Wataru Okamoto, Tomokazu Kawaoka, Masataka Tsuge…

    Citation: BMC Gastroenterology 2021 21:306

    Content type: Research article

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  2. Telephone therapist delivered CBT (TCBT) and web-based CBT (WCBT) have been shown to be significantly more clinically effective than treatment as usual (TAU) at reducing IBS symptom severity and impact at 12 m...

    Authors: Paul McCrone, Hazel Everitt, Sabine Landau, Paul Little, Felicity L. Bishop, Gilly O’Reilly, Alice Sibelli, Rachel Holland, Stephanie Hughes, Sula Windgassen, Kim Goldsmith, Nicholas Coleman, Robert Logan, Trudie Chalder and Rona Moss-Morris

    Citation: BMC Gastroenterology 2021 21:276

    Content type: Research article

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  3. Synthetic cannabinoids (SC) are chemical substances which activate cannabinoid receptors similarly to tetrahydrocannabinol, but with a higher efficacy. These substances are used as illicit recreational drugs, ...

    Authors: David Hakimian, Ariel A. Benson, Tawfik Khoury, Muhammad Massarwa, Sarah Israel, Shaden Salameh, Yonatan Gershinsky, Barak Shapira and Mordechai Muszkat

    Citation: BMC Gastroenterology 2021 21:274

    Content type: Research article

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  4. Anemia is a common extraintestinal manifestation of Inflammatory Bowel Disease (IBD) affecting negatively the patients’ quality of life. The aim of this study was to determine the frequency and real-life manag...

    Authors: Kalliopi Foteinogiannopoulou, Konstantinos Karmiris, Georgios Axiaris, Magdalini Velegraki, Antonios Gklavas, Christina Kapizioni, Charalabos Karageorgos, Christina Kateri, Anastasia Katsoula, Georgios Kokkotis, Evgenia Koureta, Charikleia Lamouri, Panagiotis Markopoulos, Maria Palatianou, Ploutarchos Pastras, Konstantinos Fasoulas…

    Citation: BMC Gastroenterology 2021 21:269

    Content type: Research article

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    The Correction to this article has been published in BMC Gastroenterology 2021 21:301

  5. Metabolic associated fatty liver disease (MAFLD) is a new definition for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and ...

    Authors: Yu-ling Chen, Hao Li, Shu Li, Zhou Xu, Shen Tian, Juan Wu, Xin-yu Liang, Xin Li, Zi-li Liu, Jun Xiao, Jia-ying Wei, Chen-yu Ma, Kai-nan Wu, Liang Ran and Ling-quan Kong

    Citation: BMC Gastroenterology 2021 21:212

    Content type: Research article

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  6. The prevalence of inflammatory bowel disease (IBD) is increasing globally, and the disease is frequently managed surgically. The aim of this study was to investigate the time trends and geographic distribution...

    Authors: Flávia Gonçalves Musauer Palacio, Lucila Marieta Perrotta de Souza, Jéssica Pronestino de Lima Moreira, Ronir Raggio Luiz, Heitor Siffert Pereira de Souza and Cyrla Zaltman

    Citation: BMC Gastroenterology 2021 21:192

    Content type: Research article

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  7. The SARS-CoV-2 pandemic is a considerable public health problem, which has caused a burden on health systems in many countries. Despite the existence of multiple studies on the different digestive symptoms and...

    Authors: Fernando Sierra-Arango, Cathalina Vergara-Cabra, Mariana Vásquez-Roldan and Erika D. Pérez-Riveros

    Citation: BMC Gastroenterology 2021 21:187

    Content type: Case report

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  8. Living with undiagnosed symptomatic coeliac disease is connected with deteriorated health, and persons with coeliac disease often wait a long time for their diagnosis. A mass screening would lower the delay, b...

    Authors: Fredrik Norström, Anna Myléus, Katrina Nordyke, Annelie Carlsson, Lotta Högberg, Olof Sandström, Lars Stenhammar, Anneli Ivarsson and Lars Lindholm

    Citation: BMC Gastroenterology 2021 21:159

    Content type: Research article

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  9. Our knowledge of the incidence and prevalence of inflammatory bowel disease (IBD) is uncertain. Recent studies reported an increase in prevalence. However, they excluded a high proportion of ambiguous cases fr...

    Authors: Karoline Freeman, Ronan Ryan, Nicholas Parsons, Sian Taylor-Phillips, Brian H. Willis and Aileen Clarke

    Citation: BMC Gastroenterology 2021 21:139

    Content type: Research article

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  10. The application of measurement instruments is a strategy to evaluate the patient's knowledge about the disease. This study aims to build an instrument that evaluates the patient's knowledge about liver cirrhosis.

    Authors: Mariana Stelmach, Kayo Augusto de Almeida Medeiros, Bárbara Justo Carvalho, Leonardo Zumerkorn Pipek, Gustavo Heluani Antunes de Mesquita, Fernanda Nii, Diego Ramos Martines, Leandro Ryuchi Iuamoto, Luiz Augusto Carneiro D’Albuquerque, Alberto Meyer and Wellington Andraus

    Citation: BMC Gastroenterology 2021 21:83

    Content type: Research article

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  11. Inflammatory bowel disease (IBD) is increasing in the Asia-Pacific region, with changes in disease phenotype and course. We aimed to assess the changing phenotypes of IBD over ten years, describe the early cli...

    Authors: M. A. Niriella, I. K. Liyanage, S. K. Kodisinghe, A. P. De Silva, A. V. G. A. M. Jayatissa, N. M. M. Navarathne, R. K. Peiris, U. P. Kalubovila, S. R. Kumarasena, R. W. Jayasekara and H. J. de Silva

    Citation: BMC Gastroenterology 2021 21:71

    Content type: Research article

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  12. We aimed to determine the prevalence of elevated alanine aminotransferase (eALT) in employees of a German chemical company, and analyze its association with sociodemographic, work- and lifestyle-related factors.

    Authors: Matthias Claus, Christoph Antoni and Bernd Hofmann

    Citation: BMC Gastroenterology 2021 21:25

    Content type: Research article

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  14. We initiated the first multi-center cluster randomized trial of endoscopic screening for esophageal cancer and gastric cancer in China. The objective of the study was to report the baseline screening findings ...

    Authors: Hongmei Zeng, Kexin Sun, Maomao Cao, Rongshou Zheng, Xibin Sun, Shuzheng Liu, Zhiyi Zhang, Yuqin Liu, Guizhou Guo, Guohui Song, Yigong Zhu, Xianghong Wu, Bingbing Song, Xianzhen Liao, Yanfang Chen, Mingyang Song…

    Citation: BMC Gastroenterology 2020 20:398

    Content type: Research article

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  15. Mucosal healing (MH) has been indicated as the therapeutic goal for ulcerative colitis (UC). Platelet count is known as an inflammation evaluation. However, the association between platelet count and MH among ...

    Authors: Shinya Furukawa, Sen Yagi, Kana Shiraishi, Kenichirou Mori, Tomoyuki Ninomiya, Keitarou Kawasaki, Yuji Mizukami, Seiyuu Suzuki, Masayoshi Uraoka, Naozumi Shibata, Sanae Nakamura, Satoshi Imamine, Hidehiro Murakami, Katsuhisa Ohashi, Masamoto Torisu, Aki Hasebe…

    Citation: BMC Gastroenterology 2020 20:384

    Content type: Research article

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  16. Development of gastrointestinal (GI) complications is adversely associated with prognosis in the critically ill. However, little is known about their impact on the outcome of non-critically ill patients. In th...

    Authors: Chun-Ta Huang, Chun-Ming Hong, Yi-Ju Tsai, Wang-Huei Sheng and Chong-Jen Yu

    Citation: BMC Gastroenterology 2020 20:383

    Content type: Research article

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  17. Nasogastric intubation (NGI) is usually challenging in patients under general anesthesia, with reported success rate at the first attempt to be less than 50%. The aim of this study was to investigate whether a...

    Authors: Ting-Yang Huang, Jr-Rung Lin and Yung-Tai Chung

    Citation: BMC Gastroenterology 2020 20:365

    Content type: Research article

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  18. The prison population is considered at high risk of acquiring infectious diseases due to confined conditions, behavioral factors, injection drug use, unprotected sexual activity, non-professional tattooing and...

    Authors: Ifeyinwa M. Okafor, Solomon O. Ugwu and Henshaw U. Okoroiwu

    Citation: BMC Gastroenterology 2020 20:360

    Content type: Research article

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  19. Chronic lead poisoning (CLP) is a rare cause of abdominal pain and is common in young children, in whom the incidence is higher than it is in adults. As the symptoms of CLP are nonspecific, misdiagnoses or mis...

    Authors: Yuan Yang, Shujun Li, Hong Wang, Morong Liu, Biguang Tuo, Huichao Wu, Shili Deng and Xuemei Liu

    Citation: BMC Gastroenterology 2020 20:335

    Content type: Case report

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  20. Disaccharides such as lactose and sucrose are sugars commonly found in human diet. They are broken down by mucosal disaccharidases in the duodenum. Previous small studies found no associations between gastroin...

    Authors: Paul Wasuwanich, Hassan Choudry, Thammasin Ingviya, Ann O. Scheimann, Karla J. AuYeung, Christine Karwowski, Susan Billet, Buford L. Nichols and Wikrom Karnsakul

    Citation: BMC Gastroenterology 2020 20:331

    Content type: Research article

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  21. The purpose of this study was to identify common gastrointestinal (GI) symptom groups using the Patient-Reported Outcomes Measurement Information System - GI symptom scales (PROMIS-GI) within a large sample of...

    Authors: Helize Vivier, Emily J. Ross and Jeffrey E. Cassisi

    Citation: BMC Gastroenterology 2020 20:326

    Content type: Research article

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  22. Inflammatory bowel diseases are classic polygenic disorders, with genetic loads that reflect immunopathological processes in response to the intestinal microbiota. Herein we performed the multiomics analysis b...

    Authors: Filip Ambrozkiewicz, Jakub Karczmarski, Maria Kulecka, Agnieszka Paziewska, Magdalena Niemira, Natalia Zeber-Lubecka, Edyta Zagorowicz, Adam Kretowski and Jerzy Ostrowski

    Citation: BMC Gastroenterology 2020 20:307

    Content type: Research article

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  23. Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed to establish a new model combing the inflammatory markers including neutrophil/lymphocyte r...

    Authors: Li Qiang, Jiao Qin, Changfeng Sun, Yunjian Sheng, Wen Chen, Bangdong Qiu, Xin Chen, Yuanfang Chen, Fei Liu and Gang Wu

    Citation: BMC Gastroenterology 2020 20:301

    Content type: Research article

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  24. Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common gastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their ...

    Authors: Mohammad Karimian, Hassan Nourmohammadi, Majid Salamati, Mohammad Reza Hafezi Ahmadi, Fatemeh Kazemi and Milad Azami

    Citation: BMC Gastroenterology 2020 20:297

    Content type: Research article

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  25. Amebiasis is a rare condition in developed countries but epidemiologically growing. Clinical manifestation may range from asymptomatic to invasive disease, amoebic liver abscess being the most common manifesta...

    Authors: Matteo Borro, Giuseppe Murdaca, Monica Greco, Simone Negrini and Maurizio Setti

    Citation: BMC Gastroenterology 2020 20:295

    Content type: Case report

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  26. The prevalence of chronic constipation is increased in females and with age or environmental (low temperature), racial, socioeconomic, and habitual risk factors. The impact of low outside temperature on consti...

    Authors: Hiroshi Mihara, Aiko Murayama, Sohachi Nanjo, Takayuki Ando, Kazuto Tajiri, Haruka Fujinami, Masaaki Yamada and Ichiro Yasuda

    Citation: BMC Gastroenterology 2020 20:284

    Content type: Research article

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  27. Reflux esophagitis (RE) and absence of Helicobacter pylori (non-H. pylori) are considered to be associated with the progression to long-segment Barrett’s esophagus (LSBE). However, it is difficult to assess this ...

    Authors: Genki Usui, Tomohiro Shinozaki, Toyohisa Jinno, Kazutoshi Fujibayashi, Teppei Morikawa, Toshiaki Gunji and Nobuyuki Matsuhashi

    Citation: BMC Gastroenterology 2020 20:270

    Content type: Research article

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  28. Hypereosinophilic syndrome (HES) is a very rare disease and usually treated with corticosteroids. Gastrointestinal (GI) cytomegalovirus (CMV) infection is also rare but frequent in patients with immunocompromi...

    Authors: Bin Luo, Chengxin Deng, Tieying Hou, Fangping Xu, Qianchao Liao, Yong Li and Junjiang Wang

    Citation: BMC Gastroenterology 2020 20:238

    Content type: Case report

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  30. Gastric cancer develops even in Helicobacter pylori(H. pylori)-uninfected patients and its typical histological feature is signet ring cell carcinoma (SRCC) within the mucosal layer. However, the biological chara...

    Authors: Mariko Kiso, Yuji Urabe, Masanori Ito, Kazuhiko Masuda, Tomoyuki Boda, Takahiro Kotachi, Kosaku Hata, Naoki Yorita, Naoko Nagasaki, Madina Abduwali, Yuich Hiyama, Shiro Oka, Shinji Tanaka and Kazuaki Chayama

    Citation: BMC Gastroenterology 2020 20:243

    Content type: Research article

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  31. Inpatient status has been shown to be a predictor of poor bowel preparation for colonoscopy; however, the optimal bowel preparation regimen for hospitalized patients is unknown. Our aim was to compare the effi...

    Authors: Patricia V. Hernandez, Jennifer L. Horsley-Silva, Diana L. Snyder, Noemi Baffy, Mary Atia, Laura Koepke, Matthew R. Buras, Elisabeth S. Lim, Kevin Ruff, Sarah B. Umar, Sameer Islam and Francisco C. Ramirez

    Citation: BMC Gastroenterology 2020 20:227

    Content type: Research article

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  32. Patients co-infected with hepatitis B virus (HBV) and the human immunodeficiency virus (HIV) are at risk of developing hepatocellular carcinoma (HCC). In sub-Saharan Africa, the overlap between high HIV and HB...

    Authors: Tongai Gibson Maponga, Richard H. Glashoff, Hannali Vermeulen, Barbara Robertson, Sean Burmeister, Marc Bernon, Jones Omoshoro-Jones, Paul Ruff, Alfred I. Neugut, Judith S. Jacobson, Wolfgang Preiser and Monique I. Andersson

    Citation: BMC Gastroenterology 2020 20:226

    Content type: Research article

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  33. Intestinal and diffuse gastric adenocarcinomas differ in clinical, epidemiological and molecular features. However, most of the concepts related to the intestinal-type are translated to gastric adenocarcinoma ...

    Authors: Paulo Pimentel Assumpção, Williams Fernandes Barra, Geraldo Ishak, Luiz Gonzaga Vaz Coelho, Felipe José Fernandez Coimbra, Helano Carioca Freitas, Emmanuel Dias-Neto, M. Constanza Camargo and Moyses Szklo

    Citation: BMC Gastroenterology 2020 20:223

    Content type: Debate

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  34. Previous studies of the relationship between dietary factors and risk of diverticulosis have yielded inconsistent results. We therefore sought to investigate the association between consumption of fruit and ve...

    Authors: Benjamin Maxner, Jessica McGoldrick, Danielle Bellavance, Po-Hong Liu, Ramnik J. Xavier, Joseph C. Yarze, Rocco Ricciardi, Kyle Staller, Daniel C. Chung and Hamed Khalili

    Citation: BMC Gastroenterology 2020 20:221

    Content type: Research article

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  35. Whipple’s disease is a rare systemic disease caused by a gram-positive bacillus called Tropheryma whipplei. First described in 1907 as an intestinal lipodystrophy with histological finding of vacuoles in the m...

    Authors: Margarita Rey R., Luis Alejandro Orozco, Katherine Marrugo, Rocio López, Erika D. Pérez-Riveros, José De la Hoz-Valle and Fernando Sierra-Arango

    Citation: BMC Gastroenterology 2020 20:197

    Content type: Case report

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  36. Non Helicobacter pylori gastric Helicobacters (NHPGHs) are associated with a range of upper gastrointestinal symptoms, histologic and endoscopic findings. For the first time in Iran, we performed a cross-sectiona...

    Authors: Shakiba Shafaie, Hami Kaboosi and Fatemeh Peyravii Ghadikolaii

    Citation: BMC Gastroenterology 2020 20:190

    Content type: Research article

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  37. Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disease characterized by multifocal venous malformations. It remains a considerable challenge in treating the gastrointestinal (GI) venous malformat...

    Authors: Yuemei Xu, Yingjie Wu, Zhenzhen Dai, Feizhen Xia and Feng Xu

    Citation: BMC Gastroenterology 2020 20:182

    Content type: Case report

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  38. Abdominal pain in adults represents a wide range of illnesses, often warranting immediate intervention. This study is to fill the gap in the knowledge about incidence, presentation, causes and mortality from a...

    Authors: Kilalo M. Mjema, Hendry R. Sawe, Irene Kulola, Amour S. Mohamed, Erasto Sylvanus, Juma A. Mfinanga and Ellen J. Weber

    Citation: BMC Gastroenterology 2020 20:173

    Content type: Research article

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  39. Diagnosing constipation remains difficult and its treatment continues to be ineffective. The reason may be that the symptom patterns of constipation differ in different demographic groups. We aimed to determin...

    Authors: Sanne J. Verkuijl, Rob J. Meinds, Monika Trzpis and Paul M. A. Broens

    Citation: BMC Gastroenterology 2020 20:168

    Content type: Research article

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  40. Post-infectious Irritable Bowel Syndrome (PI-IBS) is a functional bowel disorder which has significant impacts to a patient’s quality of life. No IBS-specific biomarker or treatment regimen for PI-IBS currentl...

    Authors: Erika Austhof, Kenzie Schaefer, Jaime Faulkner, Laura Bach, Mark Riddle and Kristen Pogreba-Brown

    Citation: BMC Gastroenterology 2020 20:159

    Content type: Research article

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  41. Incidence of ulcerative colitis (UC) in elderly population is increasing because of ageing and because of its minimal impact on life span. Data on natural history, outcomes and therapeutic strategies are limited.

    Authors: Irene Zammarchi, Francesco Lanzarotto, Rosanna Cannatelli, Francesca Munari, Federica Benini, Alessandro Pozzi, Alberto Lanzini and Chiara Ricci

    Citation: BMC Gastroenterology 2020 20:147

    Content type: Research article

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  42. Abdominal pain may be a presenting symptom of lead poisoning and is often difficult to diagnose. This study aimed to determine the prevalence of abdominal pain in patients seen in the Laghman Hakim Hospital ED...

    Authors: Mahtab Shabani, Seyed Kaveh Hadeiy, Parinaz Parhizgar, Nasim Zamani, Hamid Mehrad, Hossein Hassanian-Moghaddam and Scott Phillips

    Citation: BMC Gastroenterology 2020 20:134

    Content type: Research article

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  43. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are considered to reflect the systemic inflammatory response and clinical prognosis. However, the independent prognostic values o...

    Authors: Wei-Long Chang, Wen-Chang Yang, Xiang-Yu Zeng, Cheng-Guo Li, Zhen Xiong, Tao Wang, Rui-Zhi Zhang, Kai-Xiong Tao and Peng Zhang

    Citation: BMC Gastroenterology 2020 20:124

    Content type: Research article

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  44. Esophagogastroduodenoscopy (EGD) provides an indispensable and unambiguous inspection allowing the discovery upper gastrointestinal lesions. However, many patients are anxious about undergoing EGD. Few studies...

    Authors: Masahiro Sogabe, Toshiya Okahisa, Akira Fukuya, Kaizo Kagemoto, Yasuyuki Okada, Yuka Adachi, Takeshi Kurihara, Toru Nii, Satoshi Teramae, Hironori Tanaka, Tetsu Tomonari, Koichi Okamoto, Hiroshi Miyamoto, Masahiko Nakasono and Tetsuji Takayama

    Citation: BMC Gastroenterology 2020 20:122

    Content type: Research article

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  45. The prevalence of gastroesophageal reflux disease (GERD) in Africa is not known but is believed to be increasing because of demographic and epidemiologic transition. The main objectives of this study were to d...

    Authors: Sylvester Chuks Nwokediuko, Olusegun Adekanle, Adegboyega Akere, Abdulfatai Olokoba, Chiedozie Anyanechi, Sabo Mustapha Umar, Abubakar Maiyaki, Uchenna Ijoma, Olive Obienu, Augustine Uhunmwangho and Dennis Ndububa

    Citation: BMC Gastroenterology 2020 20:107

    Content type: Research article

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  46. The Gut and Obesity in Asia (GOASIA) Workgroup was formed to study obesity and gastrointestinal diseases in the Asia Pacific region. We aimed to 1) compare the characteristics of elderly (i.e. age ≥ 60) vs. no...

    Authors: Panyavee Pitisuttithum, Wah Kheong Chan, Panida Piyachaturawat, Kento Imajo, Atsushi Nakajima, Yosuke Seki, Kazunori Kasama, Satoru Kakizaki, Jian Gao Fan, Myeong Jun Song, Seung Kew Yoon, Yock Young Dan, Laurentius Lesmana, Khek Yu Ho, Khean Lee Goh, Vincent Wai Sun Wong…

    Citation: BMC Gastroenterology 2020 20:88

    Content type: Research article

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  47. The incidence of cirrhosis for individuals in Sweden has previously been reported as stable/low among European countries. However, Swedish population-based studies are scarce and none of them included data fro...

    Authors: Juan Vaz, Berne Eriksson, Ulf Strömberg, David Buchebner and Patrik Midlöv

    Citation: BMC Gastroenterology 2020 20:84

    Content type: Research article

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  48. There are several studies with varied and mixed results about the possible relationship between H. pylori and diabetes. Therefore, this current meta-analysis performed to determine the association between H. pylo...

    Authors: Kamyar Mansori, Yousef Moradi, Sara Naderpour, Roya Rashti, Ali Baradaran Moghaddam, Lotfolah Saed and Hedyeh Mohammadi

    Citation: BMC Gastroenterology 2020 20:77

    Content type: Research article

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  49. Advances in surgical techniques and perioperative care have improved the short- and mid-term postoperative outcomes of patients with Hirschsprung disease (HD). However, the long-term outcomes of these patients...

    Authors: Ying Dai, Yongfang Deng, Yan Lin, Runxian Ouyang and Le Li

    Citation: BMC Gastroenterology 2020 20:67

    Content type: Research article

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  50. Gastroesophageal reflux disease (GORD) is a chronic and a common condition worldwide which causes mild to severe symptoms. Private tuition attendees are a group which could have potential risk factors for GORD...

    Authors: Darsha Gunasinghe, Chathurika Gunawardhana, Shakthi Halahakoon, Ali Haneeka, Najiyya Hanim, Chamara Hapuarachchi and Devarajan Rathish

    Citation: BMC Gastroenterology 2020 20:45

    Content type: Research article

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