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Colorectal cancer

Section edited by Arndt Vogel

This section concerns all aspects of colorectal cancer including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, pathophysiology, and epidemiology.

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  1. Content type: Research article

    Colorectal cancer (CRC) is third most commonly diagnosed cancer worldwide. The aim of the prospective study was to evaluate mitosis and apoptosis of epithelial cells at each stage of colorectal neoplasia.

    Authors: Darina Kohoutova, Jaroslav Pejchal and Jan Bures

    Citation: BMC Gastroenterology 2018 18:65

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  2. Content type: Research article

    Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile...

    Authors: Thorbjørn Søren Rønn Jensen, Badar Mahmood, Morten Bach Damm, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Mark Berner Hansen and Niels Bindslev

    Citation: BMC Gastroenterology 2018 18:31

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  3. Content type: Research article

    In recent years, there has been growing concern about the overuse of colonoscopy (CC). Our objective was to evaluate the incidence rate and cumulative probability of having a potentially inadequate CC (PI-CC, ...

    Authors: Santiago Esteban, Ricardo Ricci, Sergio Terrasa and Karin Kopitowski

    Citation: BMC Gastroenterology 2017 17:162

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  4. Content type: Research article

    Genetics plays an important role in the susceptibility to sporadic colorectal cancer (CRC). In the last 10 years genome-wide association studies (GWAS) have identified over 40 independent low penetrance polymo...

    Authors: Jonathan Barontini, Marco Antinucci, Sergio Tofanelli, Maurizio Cammalleri, Massimo Dal Monte, Federica Gemignani, Pavel Vodicka, Roberto Marangoni, Ludmila Vodickova, Juozas Kupcinskas, Veronika Vymetalkova, Asta Forsti, Federico Canzian, Angelika Stein, Victor Moreno, Nicola Mastrodonato…

    Citation: BMC Gastroenterology 2017 17:104

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  5. Content type: Research article

    The risk of colorectal cancer (CRC) varies around the world and between females and males. We aimed to compare the risk of CRC among immigrants to Ontario, Canada, to its general population.

    Authors: Lawrence Paszat, Rinku Sutradhar, Ying Liu, Nancy N. Baxter, Jill Tinmouth and Linda Rabeneck

    Citation: BMC Gastroenterology 2017 17:85

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  6. Content type: Research article

    Colorectal cancer (CRC) diagnosed at <50 years is predominantly located in the distal colon and rectum. Little is known about which lesion subtypes may serve as CRC precursors in young adults. The aim of this ...

    Authors: Stephanie Wong, Ilmars Lidums, Christophe Rosty, Andrew Ruszkiewicz, Susan Parry, Aung Ko Win, Yoko Tomita, Sina Vatandoust, Amanda Townsend, Dainik Patel, Jennifer E. Hardingham, David Roder, Eric Smith, Paul Drew, Julie Marker, Wendy Uylaki…

    Citation: BMC Gastroenterology 2017 17:56

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  7. Content type: Research article

    Limited data are available for advanced colorectal neoplasm in asymptomatic individuals aged 40–49 years. We aimed to identify risk factors and develop a simple prediction model for advanced colorectal neoplas...

    Authors: Yoo Mi Park, Hee Sun Kim, Jae Jun Park, Su Jung Baik, Young Hoon Youn, Jie-Hyun Kim and Hyojin Park

    Citation: BMC Gastroenterology 2017 17:7

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  8. Content type: Research article

    A multicentre cohort study was held in Morocco, designed to evaluate the quality of life of cancer patients. The aim of this paper is to report the assessment of the quality of life of early colorectal cancer ...

    Authors: Hind Mrabti, Mounia Amziren, Ibrahim ElGhissassi, Youssef Bensouda, Narjiss Berrada, Halima Abahssain, Saber Boutayeb, Samira El Fakir, Chakib Nejjari, Abdellatif Benider, Nawfel Mellas, Omar El Mesbahi, Maria Bennani, Rachid Bekkali, Ahmed Zidouh and Hassan Errihani

    Citation: BMC Gastroenterology 2016 16:131

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  9. Content type: Research article

    The frequency and clinically important characteristics of incidental (18)F-fluorodeoxyglucose ([18 F]FDG) positron emission tomography (PET) uptake in the gastrointestinal tract (GIT) on PET/CT imaging in adul...

    Authors: Eugenia Shmidt, Vandana Nehra, Val Lowe and Amy S. Oxentenko

    Citation: BMC Gastroenterology 2016 16:125

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  10. Content type: Research article

    To assess public preferences for colorectal cancer (CRC) surveillance tests for intermediate-risk adenomas, using a hypothetical scenario.

    Authors: Bernardette Bonello, Alex Ghanouni, Harriet L. Bowyer, Eilidh MacRae, Wendy Atkin, Stephen P. Halloran, Jane Wardle and Christian von Wagner

    Citation: BMC Gastroenterology 2016 16:113

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  11. Content type: Research article

    Increasing morbidity and mortality from colorectal cancer is evident in recent years in the developing Asian nations. Particularly in Thailand and most neighbouring low-income countries, screening colonoscopy ...

    Authors: Bunchorn Siripongpreeda, Chulabhorn Mahidol, Navara Dusitanond, Tassanee Sriprayoon, Bunlung Muyphuag, Thaniya Sricharunrat, Narongchai Teerayatanakul, Watanya Chaiwong, Wipra Worasawate, Prassanee Sattayarungsee, Juthamas Sangthongdee, Jirapa Prarom, Gaidganok Sornsamdang, Kamonwan Soonklang, Kasiruck Wittayasak and Chirayu U. Auewarakul

    Citation: BMC Gastroenterology 2016 16:101

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  12. Content type: Study protocol

    Molecular studies suggest inhibition of colorectal mucosal polyamines (PAs) may be a promising approach to prevent colorectal cancer (CRC). Inhibition of ornithine decarboxylase (ODC) using low-dose eflornithi...

    Authors: Carol A. Burke, Evelien Dekker, N. Jewel Samadder, Elena Stoffel and Alfred Cohen

    Citation: BMC Gastroenterology 2016 16:87

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  13. Content type: Research article

    High-quality bowel preparation is necessary for colonoscopy. A few studies have been conducted to investigate improvement in bowel preparation quality through patient education. However, the effect of patient ...

    Authors: Jin-Seok Park, Min Su Kim, HyungKil Kim, Shin Il Kim, Chun Ho Shin, Hyun Jung Lee, Won Seop Lee and Soyoung Moon

    Citation: BMC Gastroenterology 2016 16:64

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  14. Content type: Research article

    Colorectal cancer (CRC) is the fourth leading cause of cancer-related death in Europe and the United States. Detecting the disease at an early stage improves outcomes. Risk prediction models which combine mult...

    Authors: Tom G. S. Williams, Joaquín Cubiella, Simon J. Griffin, Fiona M. Walter and Juliet A. Usher-Smith

    Citation: BMC Gastroenterology 2016 16:63

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  15. Content type: Study protocol

    Endoscopic mucosal resection (EMR) is currently the most used technique for resection of large distal colorectal polyps. However, in large lesions EMR can often only be performed in a piecemeal fashion resulti...

    Authors: Y. Backes, L. M. G. Moons, J. D. van Bergeijk, L. Berk, F. ter Borg, P. C. J. ter Borg, S. G. Elias, J. M. J. Geesing, J. N. Groen, M. Hadithi, J. C. H. Hardwick, M. Kerkhof, M. J. J. Mangen, J. W. A. Straathof, R. Schröder, M. P. Schwartz…

    Citation: BMC Gastroenterology 2016 16:56

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  16. Content type: Research article

    Incidence of anal carcinoma (AC) is increasing and timely diagnosis is critical for efficient therapy. However, there is a paucity of recent studies addressing clinical symptoms and physical findings of anal c...

    Authors: Matthias Sauter, Georg Keilholz, Helmut Kranzbühler, Norbert Lombriser, Meher Prakash, Stephan R. Vavricka and Benjamin Misselwitz

    Citation: BMC Gastroenterology 2016 16:46

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  17. Content type: Research article

    A clinical risk index employing age, sex, family history of colorectal cancer (CRC), smoking history and body mass index (BMI) may be useful for prioritizing screening with colonoscopy. The aim of this study w...

    Authors: Arlinda Ruco, David Stock, Robert J. Hilsden, S. Elizabeth McGregor, Lawrence F. Paszat, Refik Saskin and Linda Rabeneck

    Citation: BMC Gastroenterology 2015 15:162

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  18. Content type: Research article

    The aim of the present retrospective study was to analyze clinical outcome and risk factors associated with treatment outcomes according to KRAS status in patient with metastatic colorectal cancer (mCRC) treat...

    Authors: Beatrix Bencsikova, Zbynek Bortlicek, Jana Halamkova, Lenka Ostrizkova, Igor Kiss, Bohuslav Melichar, Tomas Pavlik, Ladislav Dusek, Dalibor Valik, Rostislav Vyzula and Lenka Zdrazilova-Dubska

    Citation: BMC Gastroenterology 2015 15:37

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  19. Content type: Research article

    Colonoscopy offers limited protection against right-sided colon cancer, a significant proportion of which arise from the serrated pathway of carcinogenesis. The aim of this study was to compare cap-assisted co...

    Authors: Fadi Rzouq, Neil Gupta, Sachin Wani, Prateek Sharma, Ajay Bansal and Amit Rastogi

    Citation: BMC Gastroenterology 2015 15:11

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