Table 1 Clinical characteristics of the affected family members
From: A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers syndrome
ID | II1 | III1 | III2 | I1 |
|---|---|---|---|---|
Gender | Female | Female | Male | Male |
Age (years) | 31 | 6 | 3 | 57 |
Age at onset of mucocutaneous pigmentation (years) | Earlier than 1 year | Earlier than 2 years | Earlier than 2 years | Unknown |
Order of onset of mucocutaneous pigmentation | Lip, followed by fingers, feet, oral mucosa, and face | Lip, followed by fingers and oral mucosa | Lower lip | Unknown |
Age at the first occurrence of intestinal intussusception/obstruction | 21 | No | No | 15 |
Age at the first diagnosis and resection of polyps | 21 | 6 | No | 15 |
Location of polyps | Duodenum, ileocecal region, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum | Ascending colon and rectum | No | Stomach, duodenum, ileocecal region, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum |