Table 2 Multivariate analysis of factors affecting exacerbation rate of esophageal varices after BRTO for gastric varices

Age (years)

 < 71 vs. ≥ 71

Sex

Male vs. Female

Etiology

HBV plus HCV vs. others

Albumin (g/dL)

 < 3.5 vs. ≥ 3.5

Total bilirubin (mg/dL)

 < 1.0 vs. ≥ 1.0

Prothrombin activity (%)

 < 81 vs. ≥ 81

Aspartate aminotransferase (IU/L)

 < 37 vs. ≥ 37

Alanine aminotransferase (IU/L)

 < 25 vs. ≥ 25

γ-Glutamyl transpeptidase (IU/L)

 < 64 vs. ≥ 64

Platelet count (× 10³/µL)

 < 102 vs. ≥ 102

Ammonia (µg/dL)

 < 55 vs. ≥ 55

Child–Pugh class

A vs. B or C

Fib-4 index

 < 4.80 vs. ≥ 4.80

Presence of splenomegaly

Yes vs. no

Gastric varices bleeding

Yes vs. no

Co-existence of esophageal varices

Yes vs. no

History of hepatocellular carcinoma

Yes vs. no

Diameter of LGV before BRTO

 < 5 vs. ≥ 5

Liver stiffness measurement (kPa)

 < 30.2 vs. ≥ 30.2

Pre-HVPG (mmHg)

 < 13 vs. ≥ 13

Post-HVPG (mmHg)

 < 13 vs. ≥ 13