Table 1 Clinical characteristics for the infants among the two groups
No resection (n = 68) | Bowel resection (n = 96) | p value | |
|---|---|---|---|
Male: female | 37:31 | 52:44 | 0.55 |
Gestational age (week), median (IQR) | 33.6 (30.1–36.7) | 32.9 (29.6–36.9) | 0.13 |
Birth weight (g), median (IQR) | 2492.6 (2015.6–3253.4) | 2411.8 (1989.6–3186.3) | 0.22 |
Age at diagnosis of NEC (days), median (IQR) | 15 (7–46) | 11 (6–28) | 0.025 |
No enteral nutrition before diagnosis, n (%) | 7 (10.3%) | 11 (11.5%) | 0.52 |
APGAR scores at 5 min, median (IQR) | 10 (9–10) | 9 (9–10) | 0.52 |
Vasopressor use at enrollment, n (%) | 11 (16.2%) | 15 (15.6%) | 0.55 |
Ventilator use on day of diagnosis, n (%) | 6 (8.8%) | 9 (9.4%) | 0.57 |
Acidosis, n (%) | 18 (26.5%) | 26 (27.1%) | 0.54 |
Bowel involvement, n (%) | |||
Distal ileum | 65 (95.6) | 96 (100) | 0.07 |
Distal ileum and colon | 16 (23.5) | 31 (32.3) | 0.25 |
Extent of disease, n (%) | |||
Multifocal NEC | 9 (13.2) | 32 (33.3) | 0.003 |
Localized NEC | 57 (83.8) | 17 (17.7) | < 0.001 |
Pan intestinal NEC | 2 (2.9) | 47 (49.0) | < 0.001 |