Table 4 Changes in anthropometric, biochemical, lipid profiles, and liver function parameters before and three months after treatment to eradicate H. pylori infection based on response to treatment

Anthropometric parameters

 Weight, Kg

  Before treatment

73.18 ± 14.67 (48–135)

73.74 ± 15.53 (45–110)

  After treatment

71.46 ± 12.86 (33–125)

73.44 ± 15.10 (45–110)

0.011**

0.568**

 BMI, Kg/m ²

  Before treatment

25.62 ± 4.33 (18.2–43)

27.13 ± 6.32 (16.5–42.97)

  After treatment

25.54 ± 4.41 (18.2–45)

26.9 ± 6.16 (16.5–42.97)

0.074**

0.172**

Biochemical parameters

 Hb, g/dl

  Before treatment

12.73 ± 2.05 (8.5–17.5)

13.10 ± 1.96 (8.9–16.0)

  After treatment

13.4 ± 3.39 (8.5–17.5)

12.97 ± 2.03 (8.6–17)

0.086**

0.083**

 PLT, µL 10³

  Before treatment

295.37 ± 84.21 (121–584)

284.48 ± 82.47 (150–468)

  After treatment

292.05 ± 81.75(120–484)

283.90 ± 73.85 (150–391)

0.937**

0.016**

 MCV, fL

  Before treatment

83.61 ± 5.00 (66–98)

83.86 ± 5.12 (74–98)

  After treatment

83.96 ± 5.51 (58–98)

83.53 ± 4.79 (71–95)

0.935**

0.278**

 FBS, mg/dl

  Before treatment

96.17 ± 23.12 (63–302)

97.14 ± 15.53 (68–141)

  After treatment

94.22 ± 15.12 (61–170)

97.60 ± 14.13 (71–140)

0.759**

0.346**

 BUN, mmol/L

  Before treatment

15.34 ± 6.06 (2.0–38.0)

17.04 ± 5.94 (7.0–30)

  After treatment

16.59 ± 8.70 (1.6–84)

17.91 ± 6.47 (7.0–30)

0.073**

0.782**

 Cr, mg/dL

  Before treatment

1.77 ± 1.78 (0.2–8.0)

1.56 ± 1.30 (0.6–6.0)

  After treatment

1.76 ± 1.73 (0.2–8.0)

1.51 ± 1.35 (0.6–6.5)

0.522**

0.428**

 Calcium, mg/dL

  Before treatment

8.61 ± 0.83 (5.7–10.5)

9.01 ± 0.64 (7.20–9.80)

  After treatment

8.79 ± (7.5–10.5)

9.15 ± 0.57 (8.10–10.10)

0.549**

0.634**

 TSH, mIU/L

  Before treatment

2.62 ± 1.34 (0.4–8.5)

2.29 ± 1.12 (0.3–5.50)

  After treatment

2.47 ± 1.09 (0.6–6.1)

2.25 ± 1.25 (0.3–5.75)

0.299**

0.549**

 25-OH-VitD, ng/mL

  Before treatment

26.80 ± 27.34 (6.0–65.0)

28.56 ± 13.48 (13–60)

  After treatment

29.02 ± 9.84 (3.7–56.0)

30.93 ± 12.76 (16–56)

0.210**

0.057**

Lipid profiles

 TC, mg/dL

  Before treatment

163.85 ± 37.68 (77–275)

175.14 ± 38.37 (91–265)

  After treatment

166.37 ± 35.75 (80–289)

173.51 ± 38.83 (115–279)

0.837**

0.754**

 TG, mg/dL

  Before treatment

155.65 ± 56.20 (56–253)

152.09 ± 51.06 (96.5–253.5)

  After treatment

150.94 ± 48.90 (39–271)

150.26 ± 43.41 (85–280)

< 0.0001**

0.468**

 HDL-C, mg/dL

  Before treatment

39.58 ± 17.98 (18–131)

44.41 ± 12.75 (23–80)

  After treatment

40.85 ± 11.57 (18–97)

45.35 ± 11.89 (27–74)

0.121**

0.624**

 LDL-C, mg/dL

  Before treatment

87.67 ± 29.81 (25–195)

103.65 ± 35.51 (20–165)

  After treatment

86.82 ± 28.71 (25–167)

103.85 ± 35.75 (24–185)

0.457**

0.449**

 VLDL-C, mg/dL

  Before treatment

43.34 ± 12.94 (11 − 85)

42.46 ± 17.71 (11–95)

  After treatment

39.52 ± 10.27 (7–61)

40.71 ± 15.9 (15–68)

0.265**

0.116**

Liver function parameters

 AST, U/L

  Before treatment

27.02 ± 10.09 (12–68)

26.80 ± 16.36 (9–90)

  After treatment

28.10 ± 12.62 (12–99)

26.46 ± 10.93 (10–71)

0.194**

0.059**

 ALT, U/L

  Before treatment

30.59 ± 12.65 (10–69)

30.0 ± 16.96 (10–79)

  After treatment

31.21 ± 12.74 (10–88)

31.23 ± 13.36 (11–74)

0.502**

0.096**

 ALP, IU/L

  Before treatment

210.39 ± 80.92 (61–420)

207.51 ± 68.63 (61–357)

  After treatment

214.10 ± 72.42 (61–488)

195.86 ± 64.51 (61–401)

0.804**

0.026**

 Total bilirubin, mg/dL

  Before treatment

0.97 ± 1.28 (0.1–14.0)

0.81 ± 0.52 (0.2–2.50)

  After treatment

0.94 ± 1.39 (0.1–6.0)

0.83 ± 0.51 (0.2–2.5)

0.051**

0.566**

 Direct bilirubin, mg/dL

  Before treatment

0.95 ± 1.39 (0.1–14.0)

  After treatment

0.37 ± 0.69 (0.1–6.0)

0.25 ± 0.23 (0.1–1.10)

0.24 ± 0.22 (0.1–1.10)

0.891**

0.979**