Table 2 Univariate and multivariate analyses of PFS in post-operation CRC patients
Independent factor (DFS) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Hazard ratio (95%CI) | P-value | Hazard ratio (95%CI) | P-value | |
Age (< 65/≥ 65, years) | 0.97 (0.56–1.69) | 0.899 | ||
Gender (male/female) | 1.01 (0.61–1.69) | 0.961 | ||
Type of surgery (palliative surgery/radical surgery) | 6.18 (3.74–10.22) | < 0.001 | 3.52 (1.98–6.24) | < 0.001 |
Histological type (nonspecific adenocarcinoma/specific adenocarcinoma or mixed types) | 0.56 (0.29–1.06) | 0.075 | ||
pTNM stage (III–IV/I–II) | 5.36 (2.81–10.23) | < 0.001 | 3.39 (1.69–6.80) | 0.001 |
Preoperative CA199 (> 37/≤ 37, ug/L) | 1.29 (0.71–2.35) | 0.401 | ||
Preoperative CEA (> 5/≤ 5, ug/L) | 2.11 (1.28–3.50) | 0.004 | 1.25 (0.74–2.13) | 0.407 |
Number of CTC (> 6/≤ 6) | 1.35 (0.83–2.18) | 0.224 | ||
Group (CTC-WBC/CTC) | 2.10 (1.17–3.79) | 0.013 | 1.89 (1.02–3.51) | 0.042 |