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Table 3 Factors associated with high FIB-4 index

From: Hypertension and diabetes mellitus are associated with high FIB-4 index in a health checkup examination cohort without known liver disease

Variables

Univariate analysis

Multivariate analysis

OR (95%CI)

P value

OR (95%CI)

P value

Sex (Male vs. Female)

0.740 (0.468-1.170)

0.198

  

Smoking

0.318 (0.138-0.734)

0.007

  

Habitual drinking

2.338 (1.381-3.956)

0.002

  

Obesity

1.034 (0.619-1.728)

0.899

  

Large waist circumference

1.456 (0.903-2.347)

0.123

  

Hypertension

8.217 (4.721-14.302)

 < 0.001

9.040 (4.081-20.024)

 < 0.001

Diabetes mellitus

5.935 (3.454-10.200)

 < 0.001

4.251 (1.773-10.193)

0.001

Dyslipidemia

1.354 (0.861-2.131)

0.190

  

Albumin

0.268 (0.087-0.828)

0.022

0.265 (0.083-0.841)

0.024

GGT

1.006 (1.003-1.008)

 < 0.001

  

White blood cell

0.999 (0.999-1.000)

 < 0.001

0.999 (0.999-1.000)

 < 0.001

Hemoglobin

0.919 (0.799-1.058)

0.240

  

Creatinine

1.218 (0.903-1.643)

0.197

  
  1. BMI Body mass index, FIB-4 Fibrosis-4, GGT Gamma-glutamyl transpeptidase