Table 1 Sensitivity and specificity of the H-score and the staining intensity compare to the pathologist’s evaluation
|  | Cutoff | Test database (N = 146) | Validation database (N = 177) | ||
|---|---|---|---|---|---|
n/N=Sensitivity [95%CI] | n/N=Specificity [95%CI] | n/N=Sensitivity [95%CI] | n/N=Specificity [95%CI] | ||
H-score | 168 | 37/44 = 84.1% [69.9–93.4%] | 54/102 = 52.9% [42.8–62.9%] | 53/54 = 98.2% [90.1–100%] | 68/123 = 55.3% [46.1–64.3%] |
Minimal staining intensity | 55 | 37/44 = 84.1% [69.9–93.4%] | 54/102 = 52.9% [42.8–62.9%] | 53/54 = 98.2% [90.1–100%] | 72/123 = 58.5% [49.3–67.4%] |