Table 2 Anorectal manometry test results
Variable | HSD/hEDS (n = 72) Median (IQR) | No HSD/hEDS (n = 72) Median (IQR) | p-value |
|---|---|---|---|
Mean resting sphincter pressure (mm Hg) | 80.0 (62.5–94.4) | 74.0 (56.3–97.8) | 0.73 |
Max resting sphincter pressure (mm Hg) | 89.3 (72.2–105.0) | 93 (65.8–119.1) | 0.60 |
Max squeeze sphincter pressure (mm Hg) | 166 (122.5–219.7) | 146.5 (111.7–198.5) | 0.13 |
Duration of squeeze (seconds) | 19.1 (10.9–20.4) | 16.7 (10.2–21.6) | 0.96 |
Simulated Defecation | |||
Residual anal pressures (mm Hg) | 73.8 (65.6–94.4) | 63.7 (42.8–87.6) | 0.03 |
% Relaxation during push | 3 (−20–17.5) | 8 (−3.5–27) | 0.04 |
Intra-rectal pressure during push (mm Hg) | 29.9 (13.4–51.1) | 32.8 (20.0–55.4) | 0.10 |
Rectoanal pressure gradient | −40.3 (−62.25- −19.5) | -19 (−52.9–32.9) | < 0.001 |
Sensory levels | |||
First sensation (mL) | 40 (20–60) | 40 (20–70) | 0.10 |
Urge to defecate (mL) | 75 (50–120) | 70 (50–120) | 0.25 |
Maximum tolerated (mL) | 115 (80–180) | 110 (75–160) | 0.38 |
Failed Balloon Expulsion Test, n (%) | 26 (36) | 23 (32) | 0.60 |
Dyssynergic defecation, n (%) | 55 (76) | 49 (68) | 0.26 |
Rectal hyposensitivity, n (%) | 28 (39) | 26 (36) | 0.73 |