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Table 4 The sensitivity, specificity, PPV, NPV, and accuracy of different fibrosis markers in the studied group associated with the biopsy findings

From: Accuracy of noninvasive methods for the diagnosis of liver fibrosis in children with chronic viral hepatitis

 

The area under the curve

Best cutoff

P value

Sensitivity

Specificity

PPV

NPV

Accuracy

FibroScan stiffness in kPa

0.7

5.5

0.2

60.5

85.7

96.3

26.1

64

Hyaluronic in ng/ml

0.6

16.5

0.6

60.5

71.4

92.9

22.7

62

APRI

0.6

0.105

0.4

65.1

57.1

90.3

21.1

64

  1. APRI = [(AST/upper limit of normal) / platelet count (10 9/l)] × 100