Skip to main content

Table 1 Prevalence of colorectal neoplasia, advanced neoplasia, and colorectal cancer in the cohort according to risk factors

From: A risk scoring system for advanced colorectal neoplasia in high-risk participants to improve current colorectal cancer screening in Tianjin, China

 

All subjects

Colorectal neoplasia*

Advanced neoplasia

Cancer

(n = 29,504)

(n = 14,677)

(n = 2324)

(n = 462)

n (%)

Prevalence (%)

p value

Prevalence (%)

p value

Prevalence (%)

p value

Sex, n (%)

 Female

15,710 (53.2)

6557 (44.7)

 < 0.001

897 (38.6)

 < 0.001

220 (47.6)

0.017

 Male

13,794 (46.8)

8120 (55.3)

1427 (61.4)

242 (52.4)

 Age, y, mean ± SD

63.53 (7.47)

64.55 (7.00)

 < 0.001

66.05 (6.58)

 < 0.001

67.62 (6.19)

 < 0.001

Age groups, y, n (%)

 < 50

1295 (4.4)

379 (2.6)

 < 0.001

30 (1.3)

 < 0.001

2 (0.4)

 < 0.001

 50–60

7087 (24.0)

2985 (20.3)

332 (14.3)

49 (10.6)

60–70

14,690 (49.8)

7691 (52.4)

1241 (53.4)

225 (48.7)

 ≥ 70

6432 (21.8)

3622 (24.7)

721 (31.0)

186 (40.3)

 BMI, kg/m2, mean ± SD

24.95 (3.27)

25.19 (3.26)

 < 0.001

25.28 (3.26)

 < 0.001

25.24 (3.48)

0.052

BMI groups, kg/m2, n (%)

 < 28

24,769 (84.0)

12,084 (82.3)

 < 0.001

1884 (81.1)

 < 0.001

367 (79.4)

0.009

 ≥ 28

4735 (16.0)

2593 (17.7)

440 (18.9)

95 (20.6)

Smoking status, n (%)

 Never

22,305 (75.6)

10,283 (70.1)

 < 0.001

1552 (66.8)

 < 0.001

354 (76.6)

0.644

 Current or past**

7199 (24.4)

4394 (29.9)

772 (33.2)

108 (23.4)

Alcohol intake, n (%)

 Never or occasional

26,170 (88.7)

12,534 (85.4)

 < 0.001

1901 (81.8)

 < 0.001

396 (85.7)

0.049

 Weekly

3334 (11.3)

2143 (14.6)

423 (18.2)

66 (14.3)

Regular activity***, n (%)

 Yes

13,460 (45.6)

7033 (47.9)

 < 0.001

1190 (51.2)

 < 0.001

260 (56.3)

 < 0.001

 No

16,044 (54.4)

7644 (52.1)

1134 (48.8)

202 (43.7)

Educational level, n (%)

 Low

6671 (22.6)

3254 (22.2)

0.199

466 (20.1)

0.007

86 (18.6)

0.1

 Intermediate

19,535 (66.2)

9771 (66.6)

1581 (68.0)

318 (68.8)

 High

3298 (11.2)

1652 (11.3)

277 (11.9)

58 (12.6)

Marital status, n (%)

 Married or living with significant other

28,215 (95.6)

14,047 (95.7)

0.541

2222 (95.6)

1

441 (95.5)

0.942

 Living alone

1289 (4.4)

630 (4.3)

102 (4.4)

21 (4.5)

FIT test (%)

 Negative

9205 (31.2)

4392 (29.9)

 < 0.001

466 (20.1)

 < 0.001

104 (22.5)

 < 0.001

 Positive

20,299 (68.8)

10,285 (70.1)

1858 (79.9)

358 (77.5)

HRFQ (%)

 Negative

16,044 (54.4)

8141 (55.5)

 < 0.001

1503 (64.7)

 < 0.001

281 (60.8)

0.006

 Positive

13,460 (45.6)

6536 (44.5)

821 (35.3)

181 (39.2)

  1. BMI Body mass index, FIT Faecal immunochemical test
  2. * Colorectal neoplasia includes adenoma, advanced neoplasia and cancer. Advanced neoplasia includes colorectal cancer, any colorectal adenoma that has a size of ≥ 10 mm in diameter, high-grade dysplasia, villous or tubulovillous histologic characteristics, or any combination thereof
  3. **Current smoking denotes ≥ 1 pack of cigarettes/week
  4. ***Regular activity denotes at least 30 min of exercise more than once weekly over the last year
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us