Skip to main content

Table 4 Univariate and multivariate Cox regression analysis results of OS in patients with lung-only metastasis

From: Survival nomograms for colorectal carcinoma patients with lung metastasis and lung-only metastasis, based on the SEER database and a single-center external validation cohort

Characteristic

No. of CRC patients with lung-only metastasis (N = 1065) (%)

Univariable

Multivariable

OR

95%CI

p value

OR

95%CI

p value

Age

   

< 0.001

  

< 0.001

 < 65

479(45.0)

1

  

1

  

 ≥ 65

586(55.0)

1.994

1.709–2.327

 

1.555

1.320–1.833

 

AJCC T stage

   

< 0.001

  

< 0.001

 T0

3(0.3)

1

  

1

  

 T1

125(11.7)

0.726

0.178–2.950

0.654

0.954

0.233–3.906

0.947

 T2

37(3.5)

0.435

0.102–1.862

0.262

1.005

0.231–4.370

0.994

 T3

492(46.2)

0.481

0.120–1.932

0.302

1.102

0.271–4.489

0.892

 T4

242(22.7)

0.750

0.186–3.023

0.685

1.805

0.443–7.356

0.410

 TX

166(15.6)

1.064

0.263–4.034

0.930

1.220

0.300–4.963

0.781

Marital status

   

< 0.001

  

< 0.001

 Single

521(48.9)

1

  

1

  

 Married

489(45.9)

0.639

0.548–0.747

< 0.001

0.723

0.617–0.849

< 0.001

 Other

55(5.2)

0.904

0.657–1.244

0.536

0.768

0.557–1.059

0.107

Chemotherapy

   

< 0.001

  

< 0.001

 Yes

730(68.5)

1

  

1

  

 No/Unknown

335(31.5)

3.382

2.900–3.943

 

2.904

2.463–3.423

 

Surgery

   

< 0.001

  

< 0.001

 No

479(45.0)

1

  

1

  

 Yes

586(55.0)

0.445

0.382–0.519

< 0.001

0.477

0.393–0.578

< 0.001

Grade

   

< 0.001

  

0.016

 Grade I

51(4.8)

1

  

1

  

 Grade II

626(58.8)

0.872

0.611–1.245

0.452

0.903

0.631–1.292

0.576

 Grade III

140(13.1)

1.166

0.785–1.733

0.446

1.267

0.850–1.889

0.245

 Grade IV

23(2.2)

1.198

0.659–2.177

0.553

1.214

0.665–2.216

0.529

 Unknown

225(21.1)

1.709

1.178–2.480

0.005

1.153

0.785–1.693

0.467

Radiotherapy

   

< 0.001

  

–

 Yes

267(25.1)

1

     

 No/Unknown

798(74.9)

1.467

1.228–1.752

    

AJCC N stage

   

< 0.001

  

–

 N0

471(44.2)

1

  

1

  

 N1

394(37.0)

0.705

0.597–0.833

< 0.001

   

 N2

200(18.8)

0.751

0.612–0.922

0.006

   

Site

   

< 0.001

  

–

 Right-sided colon

304(28.5)

1

  

1

  

 Left-sided colon

219(20.6)

0.698

0.564–0.864

0.001

   

 Rectosigmoid

111(10.4)

0.662

0.500–0.875

0.004

   

 Rectum

431(40.5)

0.735

0.616–0.877

0.001

   

Race

   

0.231

  

–

 White

798(74.9)

–

  

1

  

 Black

159(14.9)

  

0.682

   

 Others

108(10.0)

  

0.113

   

Gender

   

0.280

   

 Female

518(48.6)

–

  

1

 

–

 Male

547(51.4)

      

Insurance status

   

0.306

  

–

 Uninsured

45(4.2)

–

  

1

  

 Insured

1006(94.5)

  

0.182

   

 Unknown

14(1.3)

  

0.201

   
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us