Table 1 Clinical features of the study population
All(n = 250) | HBV DNA-positive(n = 77) | HBV DNA-negative (n = 173) | P | HBsAg-positive(n = 200) | HBsAg-negative(n = 50) | P | ||
|---|---|---|---|---|---|---|---|---|
Male sex | 183,73.2 | 63,81.8 | 120,69.4 | 0.040 | 145,72.5 | 38,76.0 | 0.617 | |
Age(y) | 53.90 ± 11.73 | 54.13 ± 11.76 | 53.80 ± 11.75 | 0.837 | 53.01 ± 11.35 | 57.46 ± 11.65 | 0.016 | |
Hypertension | 36,14.4 | 12,15.6 | 24,13.9 | 0.722 | 25,12.5 | 11,22.0 | 0.087 | |
Diabetes | 48,19.2 | 14,18.2 | 34,19.7 | 0.785 | 40,20.0 | 8,16.0 | 0.521 | |
CTP | A | 38,15.2 | 8,10.4 | 30,17.3 | 0.158 | 25,12.5 | 13,26.0 | 0.017 |
B/C | 212, 84.8 | 69,89.6 | 143,82.7 | 175,87.5 | 37,74.0 | |||
HBeAg-positive | 137,54.8 | 23,29.9 | 114,65.9 | < 0.001 | 107,53.5 | 30,60.0 | 0.409 | |
HBsAg-positive | 200, 80% | 70,90.9% | 130,75.1 | 0.004 | - | - | - | |
HBV DNA-positive | - | - | - | - | 70,35.0 | 7,14.0 | 0.004 | |
MELD | 13.17 ± 6.13 | 13.71 ± 5.89 | 12.92 ± 6.23 | 0.348 | 13.33 ± 6.32 | 12.52 ± 5.30 | 0.404 | |
APRI | 1.98(1.07, 3.27) | 2.58(1.27, 3.57) | 1.84(0.95,2.78) | 0.005 | 2.10(1.17,3.27) | 1.23(0.66, 2.37) | 0.002 | |
FIB-4 | 6.69(3.86, 9.91) | 7.93(4.89, 10.85) | 6.14(3.55,9.71) | 0.044 | 7.42(4.45,9.79) | 4.59(2.91,10.94) | 0.050 | |
TBIL(umol/L) | 29.07(19.82,64.74) | 30.90(20.94, 57.04) | 29.00(16.66, 58.07) | 0.301 | 28.85(17.78, 64.10) | 29.71(21.58, 43.52) | 0.942 | |
ALB(g/L) | 29.75(26.38,34.80) | 29.58(26.65, 33.00) | 30.19(25.66, 35.10) | 0.495 | 29.58(26.24,34.18) | 30.44(26.30,36.73) | 0.084 | |
SCr(umol/L) | 62.00(51.22,77.00) | 65.00(53.50,78.00) | 61.00(49.00,74.83) | 0.177 | 61.07(50.10,74.05) | 64.38(52.98,81.02) | 0.315 | |
ALT(U/L) | 33.43(21.65,66.12) | 38.74(26.43, 75.73) | 31.20(19.91, 56.32) | 0.018 | 35.07(21.97,63.35) | 27.95(17.62,45.29) | 0.044 | |
AST(U/L) | 50.74(32.50,95.80) | 62.40(35.49, 96.47) | 46.00(30.15, 82.75) | 0.071 | 53.33(35.03,92.50) | 36.85(27.09,77.23) | 0.051 | |
GGT(U/L) | 49.00(25.30,92.57) | 55.00(32.73, 99.11) | 46.00(23.39, 100.68) | 0.214 | 49.15(26.65,91.09) | 42.60(22.10,147.35) | 0.765 | |
ALP(U/L) | 97.00(72.00,150.30) | 109.10(76.60, 154.86) | 93.00(70.52, 141.75) | 0.108 | 100.36(76.20,147.65) | 80.37(58.98, 156.78) | 0.151 | |
INR | 1.35(1.15,1.55) | 1.37(1.19,1.60) | 1.33(1.15,1.58) | 0.191 | 1.37(1.15,1.62) | 1.28(1.13,1.45) | 0.090 | |
PLT(10^9/L) | 68.00(46.00,113.50) | 61(42.50,111.50) | 72(46.00,123.00) | 0.079 | 67.50(45.00,113.00) | 80.50(49.50,139.25) | 0.086 | |