Aberrant cytokeratin 7 expression by hepatocytes can predict the ductopenia grade in primary biliary cholangitis

BMC Gastroenterology

Table 3 Binary logistic regression analysis of risk factors associated with cytokeratin 7-positive hepatocytes among the clinicopathological features

	B	SE	Wald	df	Sig	Exp (B)	95% CI for EXP (B)
	B	SE	Wald	df	Sig	Exp (B)	Lower	Upper
Anti-gp210	1.858	0.790	5.534	1	0.019	6.413	1.363	30.162
Ductopenia grade	1.422	0.399	12.723	1	0.000	4.145	1.898	9.052
Interface activity	1.178	0.375	9.843	1	0.002	3.247	1.556	6.775
Constant	-4.947	1.205	16.842	1	0.000	0.007

The final variables included in the equation were anti-gp210, ductopenia grade, and interface activity, as they were risk factors for CK7⁺Hs. When other factors were fixed, the odds ratios (ORs) (and 95% confidence intervals (CIs)) of CK7⁺Hs according to anti-gp210, ductopenia grade, and interface activity were 6.413 (95% CI 1.363–30.162), 4.145 (95% CI 1.898–9.052) and 3.247 (95% CI 1.556–6.775), respectively (P < 0.05). AMA, AMA-M2, TB, DB, ALP, GGT, TA and fibrosis were not risk factors for CK7⁺Hs

ISSN: 1471-230X