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Table 2 The results of laboratory tests on admission according to the acute pancreatitis severity

From: Serum soluble T cell immunoglobulin mucin domain-3 as an early predictive marker for severity of acute pancreatitis; a retrospective analysis

Variable

MAP(n = 42)

MSAP(n = 35)

SAP(n = 17)

P-value

White blood cell count, × 109/L

9.830 ± 4.188

12.028 ± 4.320&

16.350 ± 4.527$#

< 0.001

Red blood cell count, × 1012/L

4.647 ± 0.593

4.802 ± 0.667

5.374 ± 0.828$#

0.001

Hematocrit, %

43.752 ± 13.922

45.197 ± 17.827

48.635 ± 6.860

0.513

Platelet count, × 1012/L

191.881 ± 62.304

225.086 ± 84.156

243.235 ± 82.945#

0.034

CRP, mg/L

54.088 ± 67.037

92.224 ± 75.537

194.541 ± 152.605$#

< 0.001

ALT, U/L

54.333 ± 152.244

93.870 ± 168.934

252.682 ± 602.560#

0.063

AST, U/L

73.595 ± 133.175

86.691 ± 197.879

228.735 ± 600.135

0.168

Total bilirubin, μmol/L

22.000 (14.500, 33.850)

23.400 (18.100, 39.900)

38.000 (15.65, 126.6)

0.196

Direct bilirubin, μmol/L

7.800 (3.075, 12.200)

10.900 (5.900,1 6.200)

28.000 (10.000,103.500)$#

0.001

Triglyceride, mmol/L

4.238 ± 5.253

10.244 ± 28.837

8.136 ± 7.407

0.350

Creatinine, μmol/L

41.064 ± 29.968

51.709 ± 30.791

82.206 ± 43.672$#

< 0.001

Urea, mmol/L

7.514 ± 16.428

4.809 ± 2.258

5.724 ± 2.599

0.563

Procalcitonin, ng/ml

0.188 ± 0.285

1.026 ± 2.305

5.040 ± 11.073$#

0.003

Amylase, U/L

727.219 ± 981.935

924.914 ± 853.368

895.653 ± 790.804

0.602

sTIM-3, pg/ml

911.615 ± 565.535

1462.801 ± 688.925&

2152.698 ± 632.143$#

< 0.001

IL-6, pg/ml

42.902 ± 28.821

119.501 ± 74.666&

323.593 ± 62.933$#

< 0.001

IL-10, pg/ml

1206.080 ± 566.251

964.443 ± 603.482

760.253 ± 200.418#

0.012

APACHE II score, points

3.619 ± 2.230

5.743 ± 3.119&

12.647 ± 8.177$#

< 0.001

BISAP score, points

1.214 ± 0.606

2.400 ± 0.847&

3.529 ± 0.717$#

< 0.001

MCTSI score, points

1.190 ± 0.994

4.057 ± 1.413&

4.235 ± 1.562#

< 0.001

  1. Abbreviations: MAP Mild acute pancreatitis, MSAP Moderately severe acute pancreatitis, SAP Severe acute pancreatitis, CRP C-reactive protein, ALT Alanine aminotransferases, AST Aspartate aminotransferases, IL-6 Interleukin-6, IL-10 Interleukin-10, APACHE II Acute physiology and chronic health evaluation II, BISAP Bedside index for severity in acute pancreatitis, MCTSI Modified computed tomography severity index
  2. P < 0.05 was considered statistically significant. &P < 0.05, MAP versus MSAP; #P < 0.05, MAP versus SAP; $P < 0.05, MSAP versus SAP