Table 2 The cumulative between-group recurrent bleeding-free rates during the first year and the second year-and-thereafter

Rebleeding-free rates of peptic ulcer during the first year, N (%)

Group D

(n = 60)

Group S

(n = 60)

Group C

(n = 135)

Relative risk (95% CI)

P^a

Relative risk (95% CI)

P^a

Relative risk (95% CI)

P^a

ITT analysis

60/60 (100)

59/60 (98.3)

119/135 (88.1)

1.13 (1.07–1.21)

0.003

1.12 (1.04–1.20)

0.02

1.02 (0.98–1.05)

> 0.99

PP analysis

44/44 (100)

43/44 (97.7)

113/129 (87.6)

1.14 (1.07–1.22)

0.01

1.12 (1.03–1.21)

0.08

1.02 (0.98–1.07)

> 0.99

Rebleeding-free rates of peptic ulcer during the second year-and-thereafter, N (%)

PPI-on-demand subgroup

(n = 32)

PPI-discontinued subgroup

(n = 77)

Group C

(n = 116)

Relative risk (95% CI)

P^a

Relative risk (95% CI)

P^a

Relative risk (95% CI)

P^a

ITT analysis

30/32 (93.8)

66/77 (85.7)

92/116 (79.3)

1.18 (1.04–1.34)

0.06

1.08 (0.95–1.23)

0.26

1.09 (0.96–1.24)

0.34