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Table 1 Baseline characteristics of the experimental groups and controls

From: An extended 36-week oral esomeprazole improved long-term recurrent peptic ulcer bleeding in patients at high risk of rebleeding

Parameters

Mean ± SD; n (%)

Group D

(n = 60)

Group S

(n = 60)

Group C

(n = 135)

Pa

Mean age (year)

71.0 ± 13.2

69.8 ± 12.9

70.5 ± 13.6

0.88

Female

23 (38.3)

22 (36.7)

50 (37.0)

0.98

Ulcer characteristics

 Gastric ulcer (n)

30 (50.0)

38 (63.3)

79 (58.5)

0.32

 Mean ulcer size (cm)

1.21 ± 0.77

1.36 ± 0.87

1.30 ± 1.03

0.70

Forrest classification, Ia: Ib: IIa: IIb

0: 21 (35):30 (50): 9 (15)

3 (5): 13 (21.7): 36 (60): 8 (13.3)

3 (2.2): 28 (20.7): 81 (60): 23 (17)

0.37

Rockall scores 6: 7: 8: 9: 10

20 (33.3): 33 (55): 5 (8.3): 1 (1.7): 1 (1.7)

24 (40): 15 (25): 14 (23.3): 7 (11.7): 0 (0)

36 (26.7): 48 (35.6): 37 (27.4): 13 (9.6): 1 (0.7)

0.03

ASA physical status classification, class I: II: III: IV

0:10 (16.7):46 (76.7): 4 (6.7)

0:13 (21.7):43 (71.7):4 (6.7)

0:45 (33.3):83 (61.5):7 (5.2)

0.046

Cirrhosis

8 (13.3)

7 (11.7)

23 (17.0)

0.58

End-stage renal disease with maintenance dialysis

8 (13.3)

12 (20.0)

17 (12.6)

0.38

H. pylori infectionb

12/50 (24.0)

18/55 (32.7)

45/117 (38.5)

0.19

Anti-coagulant use after enrollment

5 (8.3)

4 (6.7)

3 (2.2)

0.13

Mean hemoglobin at arrival (g/dL)

8.8 ± 2.6

8.3 ± 2.4

8.8 ± 2.6

0.33

Platelet counts < 50 × 109/L at arrival

1 (1.7)

3 (5.0)

2 (1.5)

0.30

PT prolong ≥ 4 seconds at arrival

8 (13.3)

5 (8.3)

14 (10.4)

0.67

APTT prolong ≥ 1.5-fold at arrival

2 (3.3)

3 (5.0)

2 (1.5)

0.36

Serum albumin < 3.0 g/dL at arrival

17 (28.3)

15 (25.0)

42 (31.1)

0.68

  1. Albumin: normal range 3.0–5.0 g/dL. Hemoglobin: normal range 13.5–17.0 g/dL. Platelet: normal range: 138–353 × 109/L
  2. Abbreviations: APTT activated partial thromboplastin time, ASA American Society of Anesthesiology, H. pylori Helicobacter pylori, PT prothrombin time, SD standard deviation
  3. aThe one-way analysis of variance, Pearson’s chi-square test, or Kruskal-Wallis one-way analysis of variance by ranks
  4. bSome patients did not receive H. pylori infection survey because they were in a critical situation at the primary endoscopy