Fig. 5

MiRNA-374b-5p overexpression and inhibition affect the differentiation of CD4⁺ T cells. MiRNA-374b-5p mimic or NC was transfected into T cells, followed by Th1, Th2 and Th17 activation and polarization. The proportions IFN-γ A, IL-17A B and IL-10 C in T cells. MiRNA-374b-5p inhibitor or NC was transfected into CD4⁺ T cells, followed by Th1, Th2 and Th17 activation and polarization. The proportions IFN-γ D, IL-17A E and IL-10 F in T cells. (*P < 0.05; **P < 0.01; NS, not significant)