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Fig. 4 | BMC Gastroenterology

Fig. 4

From: MiRNA-374b-5p and miRNA-106a-5p are related to inflammatory bowel disease via regulating IL-10 and STAT3 signaling pathways

Fig. 4

IL-10 is directly targeted by miRNA-374b-5p. A Sequence alignment of miRNA-374b-5p with reverse complementary IL-10. B DLR assay was performed using pmirGLO vector constructed with WT IL-10 or MUT IL-10 in the presence of miRNA-374b-5p mimic or NC. Decreases in Renilla luciferase were detected (**P < 0.01). C STAT3 is directly targeted by miRNA-106a-5p. Sequence alignment of miRNA-106a-5p with reverse complementary STAT3. D DLR assay was performed using psiCHECK-2 vector constructed with WT STAT3 or MUT STAT3 in the presence of miRNA-106a-5p mimics or NC. Decreases in Renilla luciferase were detected (**P < 0.01)

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BMC Gastroenterology

ISSN: 1471-230X

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