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Table 3 Plasma level of TNF-α、PAI-1 in different groups

From: Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome

Groups (Survived No.)

TNF-α (pg/ml )

PAI-1 (ng/L )

A (n = 8 )

101.8 ± 11.5

386.4 ± 12.8

B (n = 7 )

373.4 ± 14.1*

813.4 ± 25.9*

C (n = 10 )

258.1 ± 12.4*#

747.6 ± 27.1*#

D (n = 12 )

152.3 ± 17.3*#

512.0 ± 23.4*#

E (n = 13 )

107.6 ± 11.5#

446.7 ± 32.0*#

  1. *Compared to group A, P < 0.05, #Compared to group B, P < 0.05
  2. Group A: control group; Group B: HSOS model group; Group C: low dose LMWH group; Group D: high dose LMWH group; Group E: defibrotide group
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BMC Gastroenterology

ISSN: 1471-230X

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