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Table 1 Severity of liver injury assessed by DeLeve score (n (%))

From: Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome

Group (Survived No.)

No

Mild

Moderate

Severe

A (n = 8)

8 (100%)

0 (0)

0 (0)

0 (0)

B (n = 7)

0 (0)

0 (0)

1 (14.3)

6 (85.7)

C (n = 10)

0 (0)

0 (0)

6 (60.0)

4 (40.0)

D (n = 12)

0 (0)

2 (16.7)

7 (58.3)

3 (25.0)

E (n = 13)

0 (0)

1 (7.7)

11 (84.6)

1 (7.7)

  1. The DeLeve score of group C, D, and E were all significantly lower than group B (all P<0.001). The DeLeve score of group E were significantly lower than group C and D (both P<0.001)
  2. Group A: control group; Group B: HSOS model group; Group C: low dose LMWH group; Group D: high dose LMWH group; Group E: defibrotide group