From: A simplified multiplex methylated DNA testing for early detection of colorectal cancer in stool DNA
Characteristics | Training cohort | Validation cohort | |||||
---|---|---|---|---|---|---|---|
CRC (n = 142) | AA (n = 14) | Control (n = 85) | CRC (n = 102) | AA (n = 20) | SP (n = 64) | Control (n = 102) | |
Sex of patient | |||||||
Male | 80 (56.3%) | 11 (78.6%) | 43 (50.6%) | 56 (54.9%) | 12 (60.0%) | 35 (54.7%) | 43 (42.2%) |
Female | 62 (43.7%) | 3 (21.4%) | 42 (49.4%) | 46 (45.1%) | 8 (40.0%) | 29 (45.3%) | 59 (57.8%) |
Age at diagnosis (years) | |||||||
Median | 63 | 65 | 51 | 61 | 58 | 60 | 45 |
Mean | 61 | 63 | 49 | 61 | 57 | 57 | 46 |
Range | 20–84 | 39–76 | 26–83 | 27–89 | 33–75 | 30–92 | 21–80 |
TNM stage | – | – | – | – | – | ||
0 | 3 | 5 | |||||
I | 19 | 20 | |||||
II | 46 | 26 | |||||
III | 41 | 39 | |||||
IV | 11 | 12 | |||||
Unknown | 22 | - |