Table 2 Histological features of early colorectal cancer treated with endoscopic submucosal dissection
Variables | Total enrolled patients (n = 450) | Intramucosal cancer (n = 352) | SM1 cancer (n = 98) | P value |
|---|---|---|---|---|
Histologic type, n (%) | 0.789 | |||
Well | 343 (76.2) | 267 (75.8) | 76 (77.6) | |
Moderate | 107 (23.8) | 85 (24.1) | 22 (22.4) | |
Lymphatic invasion, n (%) | 0.004* | |||
Negative | 441 (98.0) | 349 (99.1) | 92 (93.9) | |
Positive | 9 (2.0) | 3 (0.9) | 6 (6.1) | |
Vascular invasion, n (%) | 0.009* | |||
Negative | 445 (98.9) | 351 (99.7) | 94 (95.2) | |
Positive | 5 (1.1) | 1 (0.3) | 4 (4.8) | |
Tumor budding, n (%) | 0.049* | |||
Low | 448 (99.6) | 352 (100.0) | 96 (98.0) | |
Intermediate | 2 (0.4) | 0 (0.0) | 2 (2.0) | |
Histological depth, n (%) | ||||
Intramucosa | 352 (78.2) | 352 (100.0) | ||
SM1 (< 1000 µm) | 98 (21.8) | 98 (100.0) | ||
Resection margin, n (%) | ||||
Clear resection margin | 351 (78.0) | 275 (61.1) | 77 (78.6) | 0.925 |
Positive resection margin | 99 (22.0) | 77 (21.9) | 21 (21.4) | |
Curative resection, n (%) | 342 (76.0) | 272 (77.3) | 70 (71.4) | 0.231 |