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Table 5 Multivariate analysis of clinicopathological, mutational and transcriptional factors on patient prognosis

From: Mutational and transcriptional alterations and clinicopathological factors predict the prognosis of stage I hepatocellular carcinoma

 

Multivariate

HR (95% CI)

P value

Sex

  

Female

Reference

 

Male

0.32 (0.11–0.96)

0.041

Race

  

Asia

Reference

 

Black or African American

15.92 (3.10–81.68)

0.001

White

3.22 (1.09–9.53)

0.034

TMB

  

Low

Reference

 

High

7.81 (2.24–27.24)

0.001

Neoplasm histologic grade

  

G1

Reference

 

G2

1.56 (0.37–6.50)

0.542

G3

3.07 (0.63–15.03)

0.166

G4

14.01 (1.98–99.03)

0.008

Child Pugh grade B or C

  

A

Reference

 

B or C

4.11 (1.11–15.21)

0.034

MMRN1_exp

1.35 (1.00–1.83)

0.050

OXT_exp

0.77 (0.62–0.96)

0.019

COX6A2_exp

1.19 (1.03–1.39)

0.023

  1. P < 0.05 for bold P values
  2. HR, hazard ratio; CI, confidence interval; TMB, tumor mutational burden; G, grade; exp, expression
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BMC Gastroenterology

ISSN: 1471-230X

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