| Univariate | Multivariate | ||
---|---|---|---|---|
 | HR (95% CI) | P value | HR (95% CI) | P value |
Neoplasm histologic grade | Â | Â | Â | Â |
G1 | Reference | Â | Reference | Â |
G2 | 1.07 (0.42–2.70) | 0.886 | 1.38 (0.29–6.50) | 0.681 |
G3 | 0.84 (0.31–2.26) | 0.723 | 2.74 (0.49–15.33) | 0.252 |
G4 | 2.08 (0.57–7.54) | 0.266 | 10.78 (1.30–89.59) | 0.028 |
Child Pugh classification grade | Â | Â | Â | Â |
A | Reference | Â | Reference | Â |
B or C | 1.85 (0.64–5.36) | 0.255 | 10.28 (1.82–57.98) | 0.008 |
BMI | Â | Â | Â | Â |
Normal | Reference | Â | Reference | Â |
High | 1.36 (0.70–2.67) | 0.363 | 0.30 (0.10–0.89) | 0.029 |
Low | 0.00 (0.00-Inf) | 0.997 | 0.00 (0.00-Inf) | 0.998 |
Age | Â | Â | Â | Â |
Age | 1.04 (1.02–1.07) | 0.003 | 1.08 (1.02–1.14) | 0.007 |
Sex | Â | Â | Â | Â |
Female | Reference | Â | Reference | Â |
Male | 0.49 (0.27–0.92) | 0.025 | 0.76 (0.24–2.38) | 0.639 |
Race | Â | Â | Â | Â |
Asia | Reference | Â | Reference | Â |
Black or African American | 5.95 (1.62–21.88) | 0.007 | 25.53 (3.97–164.23) | 0.001 |
White | 3.05 (1.47–6.33) | 0.003 | 3.86 (0.86–17.35) | 0.078 |
TMB | Â | Â | Â | Â |
Low | Reference | Â | Reference | Â |
High | 2.69 (1.10–6.58) | 0.030 | 1.97 (0.30–12.88) | 0.480 |
Fibrosis Ishak score | Â | Â | Â | Â |
0: No fibrosis | Reference | Â | Reference | Â |
1, 2: Portal fibrosis | 1.46 (0.41–5.17) | 0.556 | 1.18 (0.15–9.43) | 0.877 |
3, 4: Fibrous speta | 1.49 (0.43–5.14) | 0.530 | 1.86 (0.44–7.79) | 0.397 |
5, 6: Incomplete or established cirrhosis | 0.79 (0.30–2.07) | 0.634 | 1.89 (0.51–7.08) | 0.344 |