Table 2 Clinicopathological parameters correlated with poorly differentiated cluster grade
Parameters | PDC grade | P | ||
|---|---|---|---|---|
G 1 (%) | G 2 (%) | G 3 (%) | ||
Depth of submucosal invasion |  |  |  | < 0.001 |
 > 1 mm | 25 (19.1) | 20 (55.6) | 15 (93.8) |  |
 ≤ 1 mm | 106 (80.9) | 16 (44.4) | 1 (6.3) |  |
Stratification of submucosal invasion | Â | Â | Â | 0.008 |
 SM 1 | 30(22.9) | 2 (5.6) | 0 (0.0) |  |
 SM 2 | 101 (77.1) | 34 (94.4) | 16 (100.0) |  |
Tumor size (mm) | Â | Â | Â | 0.470 |
 > 20 | 37 (28.2) | 14 (38.9) | 5 (31.3) |  |
 ≤ 20 | 94 (71.8) | 22 (61.1) | 11 (68.8) |  |
Tumor volume (mm3) | Â | Â | Â | 0.596 |
 > 583.96 | 29 (22.1) | 9 (25.0) | 2 (12.5) |  |
 ≤ 583.96 | 102 (77.9) | 27 (75.0) | 14 (87.5) |  |
TB grade |  |  |  | < 0.001 |
 Bd 1 | 114 (87.0) | 16 (44.4) | 1 (6.3) |  |
 Bd 2 | 15 (11.5) | 15 (41.7) | 8 (50.0) |  |
 Bd 3 | 2 (1.5) | 5 (13.9) | 7 (43.8) |  |
Tumor grade (WHO) | Â | Â | Â | 0.457 |
 1 | 25 (19.1) | 5 (13.9) | 2 (12.5) |  |
 2 | 89 (67.9) | 25 (69.4) | 14 (87.5) |  |
 3 | 17 (13.0) | 6 (16.7) | 0 (0.0) |  |
PNI | Â | Â | Â | 0.003 |
 Absence | 125 (95.4) | 30 (83.3) | 12 (75.0) |  |
 Presence | 6 (4.6) | 6 (16.7) | 4 (25.0) |  |
LVI | Â | Â | Â | 0.001 |
 Absence | 126 (96.2) | 30 (83.3) | 12 (75.0) |  |
 Presence | 5 (3.8) | 6 (16.7) | 4 (25.0) |  |
Mucinous composition | Â | Â | Â | 0.015 |
 Absence | 9 (6.9) | 8 (22.2) | 3 (18.8) |  |
 Presence | 122 (93.1) | 28 (77.8) | 13 (81.3) |  |
Location | Â | Â | Â | 0.149 |
 Right colon | 14 (10.7) | 1 (2.8) | 0 (0.0) |  |
 Left colon | 26 (19.8) | 5 (13.9) | 6 (37.5) |  |
 Rectum | 91 (69.5) | 30 (83.3) | 10 (62.5) |  |
Ulceration | Â | Â | Â | 0.101 |
 Absence | 115 (87.8) | 7 (19.4) | 5 (31.3) |  |
 Presence | 16 (12.2) | 29 (80.6) | 11 (68.8) |  |
Number of lesions | Â | Â | Â | 0.413 |
 Unifocal | 128 (97.7) | 35 (97.2) | 15 (93.8) |  |
 Multifocal | 3 (2.3) | 1 (2.8) | 1 (6.3) |  |
Operation method | Â | Â | Â | 0.402 |
 Laparotomy | 59 (45.0) | 20 (55.6) | 6 (37.5) |  |
 Laparoscopy | 72 (55.0) | 16 (44.4) | 10 (62.5) |  |
Postoperative adjuvant chemotherapy |  |  |  | < 0.001 |
 Absence | 130 (99.2) | 29 (80.6) | 2 (12.5) |  |
 Presence | 1 (0.8) | 7 (19.4) | 14 (87.5) |  |
Age | Â | Â | Â | 0.568 |
 ≤ 60 | 48 (36.6) | 13 (36.1) | 8 (50.0) |  |
 > 60 | 83 (63.4) | 23 (63.9) | 8 (50.0) |  |
Sex | Â | Â | Â | 0.052 |
 Male | 87 (66.4) | 16 (44.4) | 9 (56.3) |  |
 Female | 44 (33.6) | 20 (55.6) | 7 (43.8) |  |
BMI | Â | Â | Â | 0.097 |
 ≤ 28 | 107 (81.7) | 25 (69.4) | 15 (93.8) |  |
  > 28 | 24 (18.3) | 11 (30.6) | 1 (6.3) |  |
HP | Â | Â | Â | 0.671 |
 Absence | 86 (65.6) | 21 (58.3) | 11 (68.8) |  |
 Presence | 45 (34.4) | 15 (41.7) | 5 (31.3) |  |
DM | Â | Â | Â | 0.802 |
 Absence | 111 (84.7) | 32 (88.9) | 14 (87.5) |  |
 Presence | 20 (15.3) | 4 (11.1) | 2 (12.5) |  |
CHD | Â | Â | Â | 0.119 |
 Absence | 123 (93.9) | 30 (83.3) | 14 (87.5) |  |
 Presence | 8 (6.1) | 6 (16.7) | 2 (12.5) |  |