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Table 1 Clinicopathological parameters correlated with lymph node metastasis

From: Poorly differentiated cluster grade-a vital predictor for lymph node metastasis and oncological outcomes in patients with T1 colorectal cancer: a retrospective study

Parameters

LNM

P

Positive (%)

Negative (%)

PDC grade

  

< 0.001

 G 1

1 (5.0)

130 (79.8)

 

 G 2

6 (30.0)

30 (18.4)

 

 G 3

13 (65.0)

3 (1.8)

 

Depth of submucosal invasion

  

< 0.001

 > 1 mm

17 (85.0)

43 (26.4)

 

 ≤ 1 mm

3 (15.0)

120 (73.6)

 

Stratification of submucosal invasion

  

0.535

 SM 1

2 (10.0)

30 (18.4)

 

 SM 2

18 (90.0)

133 (81.6)

 

Tumor size (mm)

  

0.565

 > 20

5 (25.0)

51 (31.3)

 

 ≤ 20

15 (75.0)

112 (68.7)

 

Tumor volume (mm3)

  

0.432

 > 583.96

3 (15.0)

37 (22.7)

 

 ≤ 583.96

17 (85.0)

126 (77.3)

 

TB grade

  

< 0.001

 Bd 1

3 (15.0)

128 (78.5)

 

 Bd 2

8 (40.0)

30 (18.4)

 

 Bd 3

9 (45.0)

5 (3.1)

 

Tumor grade (WHO)

  

0.364

 1

2 (10.0)

30 (18.4)

 

 2

17 (85.0)

111 (68.1)

 

 3

1 (5.0)

22 (13.5)

 

PNI

  

< 0.001

 Absence

13 (65.0)

154 (94.5)

 

 Presence

7 (35.0)

9 (5.5)

 

LVI

  

0.002

 Absence

14 (70.0)

154 (94.5)

 

 Presence

6 (30.0)

9 (5.5)

 

Mucinous composition

  

0.463

 Absence

3 (15.0)

17 (10.4)

 

 Presence

17 (85.0)

146 (89.6)

 

Location

  

0.386

 Right colon

0 (0.0)

15 (9.2)

 

 Left colon

5 (25.0)

32 (19.6)

 

 Rectum

15 (75.0)

116 (71.2)

 

Ulceration

  

0.516

 Absence

16 (80.0)

139 (85.3)

 

 Presence

4 (20.0)

24 (14.7)

 

Number of lesions

  

0.443

 Unifocal

19 (95.0)

159 (97.5)

 

 Multifocal

1 (5.0)

4 (2.5)

 

Operation method

  

0.540

 Laparotomy

8 (40.0)

77 (47.2)

 

 Laparoscopy

12 (60.0)

86 (52.8)

 

Postoperative adjuvant chemotherapy

  

< 0.001

 Absence

1 (5.0)

160 (98.2)

 

 Presence

19 (95.0)

3 (1.8)

 

Age

  

0.229

 ≤ 60

10 (50.0)

104 (63.8)

 

  > 60

10 (50.0)

59 (36.2)

 

Sex

  

0.276

 Male

10 (50.0)

61 (37.4)

 

 Female

10 (50.0)

102 (62.6)

 

BMI

  

0.249

 ≤ 28

18 (90.0)

129 (79.1)

 

 > 28

2 (10.0)

34 (20.9)

 

HP

  

0.657

 Absence

12 (60.0)

106 (65.0)

 

 Presence

8 (40.0)

57 (35.0)

 

DM

  

0.211

 Absence

19 (95.0)

138 (84.7)

 

 Presence

1 (5.0)

25 (15.3)

 

CHD

  

0.294

 Absence

17 (85.0)

150 (92.0)

 

 Presence

3 (15.0)

13 (8.0)

 
  1. LNM lymph node metastasis, PDC poorly differentiated cluster, TB tumor budding, PNI perineural invasion, LVI lymphvascular invasion, BMI body mass index, HP hypertension, DM diabetes mellitus, CHD coronary heart disease